Difference between revisions of "Phosphatase Superfamily CC1"

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Fungi, plants and many protists also have the [[Phosphatase_Family_OCA|OCA]] family.  
 
Fungi, plants and many protists also have the [[Phosphatase_Family_OCA|OCA]] family.  
  
It shares a Cys-based catalytic motif, CX5R with another two superfamilies [[Phosphatase_Superfamily_Cys-based_II| Cys-based I]] and [[Phosphatase_Superfamily_Cys-based_II|Cys-based III]], but it has distinct structure from them.
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It shares a Cys-based catalytic motif, CX5R with another two superfamilies [[Phosphatase_Superfamily_CC2I| CC2]] and [[Phosphatase_Superfamily_CC3|CC3]], but it has distinct structure from them.

Revision as of 20:32, 6 December 2014

Phosphatase classification: Superfamily CC1

CC1 (or Cysteine-based, group 1) is the largest phosphatase superfamily. It consists of three families in human:

- Classic PTP (Protein Tyrosine Phosphatase; generally tyrosine specific)

- DSP and PTEN (Dual Specificity Phosphatases; tyr/ser/thr specific)

- Myotubularin (lipid specific).

Fungi, plants and many protists also have the OCA family.

It shares a Cys-based catalytic motif, CX5R with another two superfamilies CC2 and CC3, but it has distinct structure from them.