Difference between revisions of "Phosphatase Superfamily CC1"

From PhosphataseWiki
Jump to: navigation, search
Line 5: Line 5:
 
- [[Phosphatase_Family_PTP|Classic PTP]] (Protein Tyrosine Phosphatase; generally tyrosine specific)
 
- [[Phosphatase_Family_PTP|Classic PTP]] (Protein Tyrosine Phosphatase; generally tyrosine specific)
  
- [[Phosphatase_Family_DSP_PTEN|DSP and PTEN]] (Dual Specificity Phosphatases; tyr/ser/thr specific)
+
- [[Phosphatase_Family_DSP|DSP]] (Dual Specificity Phosphatases; tyr/ser/thr specific)
 +
 
 +
- [[Phosphatase_Family_PTEN|PTEN]] Lipid phosphatases closely related to DSPs.
  
 
- [[Phosphatase_Family_Myotubularin|Myotubularin]] (lipid specific).
 
- [[Phosphatase_Family_Myotubularin|Myotubularin]] (lipid specific).

Revision as of 01:29, 28 December 2014

Phosphatase classification: Superfamily CC1

CC1 (or Cysteine-based, group 1) is the largest phosphatase superfamily. It consists of three families in human:

- Classic PTP (Protein Tyrosine Phosphatase; generally tyrosine specific)

- DSP (Dual Specificity Phosphatases; tyr/ser/thr specific)

- PTEN Lipid phosphatases closely related to DSPs.

- Myotubularin (lipid specific).

Fungi, plants and many protists also have the OCA family.

It shares a Cys-based catalytic motif, CX5R with another two superfamilies CC2 and CC3, but it has distinct structure from them.