Difference between revisions of "Phosphatase Subfamily CTDSPL2"
From PhosphataseWiki
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| − | + | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Family_FCP|FCP]]: [[Phosphatase_Subfamily_HSPC129|HSPC129]] | |
| + | __NOTOC__ | ||
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HSPC129 is also known as HSPC058, and CTDSPL2 (CTD small phosphatase like 2). It has not been well characterized, though in vitro assay showed its phosphatase activity toward CTD. <cite>qian</cite>. | HSPC129 is also known as HSPC058, and CTDSPL2 (CTD small phosphatase like 2). It has not been well characterized, though in vitro assay showed its phosphatase activity toward CTD. <cite>qian</cite>. | ||
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See [[CTD_Phosphorylation|Phosphorylation of RNA polymerase II C-terminal domain]]. | See [[CTD_Phosphorylation|Phosphorylation of RNA polymerase II C-terminal domain]]. | ||
| − | == | + | ===Evolution=== |
HSPC129 is conserved from Monosiga to human but lost in fruit fly. | HSPC129 is conserved from Monosiga to human but lost in fruit fly. | ||
| − | == Domain | + | ===Domain Structure=== |
| − | == Catalytic activity == | + | ===Catalytic activity=== |
| − | == Curation notes == | + | ===Curation notes=== |
| − | == References == | + | ===References=== |
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<biblio> | <biblio> | ||
#qian pmid=17487459 | #qian pmid=17487459 | ||
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| − | == Links == | + | ===Links=== |
[http://www.ncbi.nlm.nih.gov/gene/51496 Human HSPC129] from NCBI Gene | [http://www.ncbi.nlm.nih.gov/gene/51496 Human HSPC129] from NCBI Gene | ||
Revision as of 05:24, 29 December 2014
Phosphatase Classification: FCP: HSPC129
HSPC129 is also known as HSPC058, and CTDSPL2 (CTD small phosphatase like 2). It has not been well characterized, though in vitro assay showed its phosphatase activity toward CTD. [1].
Related Kinases
See Phosphorylation of RNA polymerase II C-terminal domain.
Evolution
HSPC129 is conserved from Monosiga to human but lost in fruit fly.
Domain Structure
Catalytic activity
Curation notes
References
- Qian H, Ji C, Zhao S, Chen J, Jiang M, Zhang Y, Yan M, Zheng D, Sun Y, Xie Y, and Mao Y. Expression and characterization of HSPC129, a RNA polymerase II C-terminal domain phosphatase. Mol Cell Biochem. 2007 Sep;303(1-2):183-8. DOI:10.1007/s11010-007-9472-z |
Links
Human HSPC129 from NCBI Gene
