Difference between revisions of "Phosphatase Fold HP"

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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_PGM|Fold PGM]]
 
[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_PGM|Fold PGM]]
  
PGM is short for Phosphoglycerate mutase. It can be classified as below <cite>jedrzejas00, rigden01</cite>:
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PGM is short for PhosphoGlycerate Mutase.  
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It can be classified as below <cite>jedrzejas00, rigden01</cite>:
  
 
* Monophosphoglycerate mutase (mPGM) - catalyzes the interconversion of 3-phosphoglycerate (3PGA) and 2-phosphoglycerate (2PGA)
 
* Monophosphoglycerate mutase (mPGM) - catalyzes the interconversion of 3-phosphoglycerate (3PGA) and 2-phosphoglycerate (2PGA)
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* Bisphosphoglycerate mutase (bPGM) - catalyzes primarily the interconversion of 1,3-phosphoglycerate (13PGA) and 23PGA
 
* Bisphosphoglycerate mutase (bPGM) - catalyzes primarily the interconversion of 1,3-phosphoglycerate (13PGA) and 23PGA
  
dPGM is also known as [[Phosphatase_Superfamily_HP|histidine phosphatase]].
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According to SCOP database, the fold contains single superfamily, which include the families below:
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* c.60.1.1: Cofactor-dependent phosphoglycerate mutase
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* c.60.1.2: Histidine acid phosphatase
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* c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain
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According to Pfam database,
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dPGM is also known as [[Phosphatase_Superfamily_HP1|histidine phosphatase, branch 1]].
  
 
=== References ===
 
=== References ===

Revision as of 18:33, 1 January 2015

Phosphatase Classification: Fold PGM

PGM is short for PhosphoGlycerate Mutase.

It can be classified as below [1, 2]:

  • Monophosphoglycerate mutase (mPGM) - catalyzes the interconversion of 3-phosphoglycerate (3PGA) and 2-phosphoglycerate (2PGA)
    • dependent on 23PGA as a cofactor (dPGM) - found in animal, fungi, and bacteria
    • independent of 23PGA as a cofactor (iPGM) - found in plants, and bacteria
  • Bisphosphoglycerate mutase (bPGM) - catalyzes primarily the interconversion of 1,3-phosphoglycerate (13PGA) and 23PGA

According to SCOP database, the fold contains single superfamily, which include the families below:

  • c.60.1.1: Cofactor-dependent phosphoglycerate mutase
  • c.60.1.2: Histidine acid phosphatase
  • c.60.1.4: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain

According to Pfam database,

dPGM is also known as histidine phosphatase, branch 1.

References

Error fetching PMID 10958932:
Error fetching PMID 11514674:
  1. Error fetching PMID 10958932: [jedrzejas00]
  2. Error fetching PMID 11514674: [rigden01]
All Medline abstracts: PubMed | HubMed