Difference between revisions of "Phosphatase Family MDP1"
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Group_HAD|Superfamily HAD]]: [[Phosphatase_Family_MDP1|Family MDP1]] | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Group_HAD|Superfamily HAD]]: [[Phosphatase_Family_MDP1|Family MDP1]] | ||
| − | MDP1 | + | This family typically has one member in unikonts (MDP1 in human), though it is lost from Drosophila and C. elegant. It has been reported as a putative tyrosine phosphatase <cite>Peisach04</cite>. However, a later study reported that it is a protein-fructosamine-6-phosphatase potentially involved in glycation repair <cite>Fortpied06</cite>. This activity was 100-fold higher than it's tyrosine phosphatase activity, and MDP1 has not been shown to have activity on phosphopeptides <cite>Selengut</cite>. |
== References == | == References == | ||
| − | |||
<biblio> | <biblio> | ||
#Peisach04 pmid=15461449 | #Peisach04 pmid=15461449 | ||
| + | #Selengut pmid=10889041 | ||
#Fortpied06 pmid=16670083 | #Fortpied06 pmid=16670083 | ||
</biblio> | </biblio> | ||
Revision as of 23:55, 26 May 2014
Phosphatase Classification: Superfamily HAD: Family MDP1
This family typically has one member in unikonts (MDP1 in human), though it is lost from Drosophila and C. elegant. It has been reported as a putative tyrosine phosphatase [1]. However, a later study reported that it is a protein-fructosamine-6-phosphatase potentially involved in glycation repair [2]. This activity was 100-fold higher than it's tyrosine phosphatase activity, and MDP1 has not been shown to have activity on phosphopeptides [3].
References
Error fetching PMID 15461449:
Error fetching PMID 10889041:
Error fetching PMID 16670083:
Error fetching PMID 10889041:
Error fetching PMID 16670083:
- Error fetching PMID 15461449:
- Error fetching PMID 16670083:
- Error fetching PMID 10889041:
