Difference between revisions of "Phosphatase Family OCA"
From PhosphataseWiki
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_Cys-based_I|Superfamily Cys-based I]]: [[Phosphatase_Family_OCA|OCA]] | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_Cys-based_I|Superfamily Cys-based I]]: [[Phosphatase_Family_OCA|OCA]] | ||
| − | OCA | + | OCA family is named after the five member genes in yeast. OCA stands for Oxidant-induced Cell-cycle Arrest. The physiological substrates of OCAs are still unclear. But, [[Gene_OCA3|OCA3]] has been shown to control intracellular localization of Gln3 (a phosphorylated transcriptional activator), in cooperation with Npr1 kinase <cite>Harashima08</cite>. OCAs also have been shown to be involved in telomere capping and uncapping <cite>lydall08</cite>. |
| + | It is found in most if not all of eukaryotes except eumetazoan (i.e. fungi, plants, protists, monosiga, and sponge). | ||
| + | |||
| + | The family is also called as plant and fungi atypical (PFA)-DSPs <cite>Pulido07 Pulido11</cite>. | ||
| + | |||
| + | ===== Reference ===== | ||
| + | <biblio> | ||
| + | #Harashima08 pmid=18166280 | ||
| + | </biblio> | ||
=== Reference === | === Reference === | ||
<biblio> | <biblio> | ||
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#Pulido11 pmid=21409566 | #Pulido11 pmid=21409566 | ||
#lydall08 pmid=18845848 | #lydall08 pmid=18845848 | ||
| + | #Harashima08 pmid=18166280 | ||
</biblio> | </biblio> | ||
Revision as of 21:28, 28 May 2014
Phosphatase Classification: Superfamily Cys-based I: OCA
OCA family is named after the five member genes in yeast. OCA stands for Oxidant-induced Cell-cycle Arrest. The physiological substrates of OCAs are still unclear. But, OCA3 has been shown to control intracellular localization of Gln3 (a phosphorylated transcriptional activator), in cooperation with Npr1 kinase [1]. OCAs also have been shown to be involved in telomere capping and uncapping [2].
It is found in most if not all of eukaryotes except eumetazoan (i.e. fungi, plants, protists, monosiga, and sponge).
The family is also called as plant and fungi atypical (PFA)-DSPs [3, 4].
Reference
- Hirasaki M, Kaneko Y, and Harashima S. Protein phosphatase Siw14 controls intracellular localization of Gln3 in cooperation with Npr1 kinase in Saccharomyces cerevisiae. Gene. 2008 Feb 15;409(1-2):34-43. DOI:10.1016/j.gene.2007.11.005 |
Reference
Error fetching PMID 17976645:
Error fetching PMID 21409566:
Error fetching PMID 18845848:
Error fetching PMID 18166280:
Error fetching PMID 21409566:
Error fetching PMID 18845848:
Error fetching PMID 18166280:
- Error fetching PMID 18166280:
- Error fetching PMID 18845848:
- Error fetching PMID 17976645:
- Error fetching PMID 21409566: