Difference between revisions of "Phosphatase Family OCA"

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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_Cys-based_I|Superfamily Cys-based I]]:  [[Phosphatase_Family_OCA|OCA]]
 
[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_Cys-based_I|Superfamily Cys-based I]]:  [[Phosphatase_Family_OCA|OCA]]
  
OCA is found in most if not all of fungi, plants, protists (chromalveolata, excavata), as well as monosiga and sponge. The family is named after yeast phosphatases OCA1, OCA2, [[Gene_OCA3|OCA3]], OCA4, OCA6. OCA is short for Oxidant-induced Cell-cycle Arrest. They have been shown involved in telomere capping and uncapping <cite>lydall08</cite>. It is also called as plant and fungi atypical (PFA)-DSPs <cite>Pulido07 Pulido11</cite>.
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OCA family is named after the five member genes in yeast. OCA stands for Oxidant-induced Cell-cycle Arrest. The physiological substrates of OCAs are still unclear. But, [[Gene_OCA3|OCA3]] has been shown to control intracellular localization of Gln3 (a phosphorylated transcriptional activator), in cooperation with Npr1 kinase <cite>Harashima08</cite>. OCAs also have been shown to be involved in telomere capping and uncapping <cite>lydall08</cite>.  
  
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It is found in most if not all of eukaryotes except eumetazoan (i.e. fungi, plants, protists, monosiga, and sponge).
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The family is also called as plant and fungi atypical (PFA)-DSPs <cite>Pulido07 Pulido11</cite>.
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===== Reference =====
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<biblio>
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#Harashima08 pmid=18166280
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</biblio>
 
=== Reference ===
 
=== Reference ===
 
<biblio>
 
<biblio>
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#Pulido11 pmid=21409566
 
#Pulido11 pmid=21409566
 
#lydall08 pmid=18845848
 
#lydall08 pmid=18845848
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#Harashima08 pmid=18166280
 
</biblio>
 
</biblio>

Revision as of 21:28, 28 May 2014

Phosphatase Classification: Superfamily Cys-based I: OCA

OCA family is named after the five member genes in yeast. OCA stands for Oxidant-induced Cell-cycle Arrest. The physiological substrates of OCAs are still unclear. But, OCA3 has been shown to control intracellular localization of Gln3 (a phosphorylated transcriptional activator), in cooperation with Npr1 kinase [1]. OCAs also have been shown to be involved in telomere capping and uncapping [2].

It is found in most if not all of eukaryotes except eumetazoan (i.e. fungi, plants, protists, monosiga, and sponge).

The family is also called as plant and fungi atypical (PFA)-DSPs [3, 4].

Reference
  1. Hirasaki M, Kaneko Y, and Harashima S. Protein phosphatase Siw14 controls intracellular localization of Gln3 in cooperation with Npr1 kinase in Saccharomyces cerevisiae. Gene. 2008 Feb 15;409(1-2):34-43. DOI:10.1016/j.gene.2007.11.005 | PubMed ID:18166280 | HubMed [Harashima08]

Reference

Error fetching PMID 17976645:
Error fetching PMID 21409566:
Error fetching PMID 18845848:
Error fetching PMID 18166280:
  1. Error fetching PMID 18166280: [Harashima08]
  2. Error fetching PMID 18845848: [lydall08]
  3. Error fetching PMID 17976645: [Pulido07]
  4. Error fetching PMID 21409566: [Pulido11]
All Medline abstracts: PubMed | HubMed