Difference between revisions of "Phosphatase Family OCA"

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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]]:  [[Phosphatase_Family_OCA|OCA]]
 
[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]]:  [[Phosphatase_Family_OCA|OCA]]
  
OCA family is named after the five member genes in yeast. OCA stands for Oxidant-induced Cell-cycle Arrest. The physiological substrates of OCAs are still unclear. But, [[Gene_OCA3|OCA3]] has been shown to control intracellular localization of Gln3 (a phosphorylated transcriptional activator), in cooperation with Npr1 kinase <cite>Harashima08</cite>. OCAs also have been shown to be involved in telomere capping and uncapping <cite>lydall08</cite>.  
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The OCA family is named after the five member genes in yeast (OCA1-5 = Oxidant-induced Cell-cycle Arrest). Yeast OCA members are involved in cell cycle arrest in response to oxidative damage<cite>Alic</cite>, in telomere capping <cite>lydall08</cite>, in actin organization <cite>Care</cite>. [[Gene_OCA3|OCA3]] has been shown to control intracellular localization of Gln3 (a phosphorylated transcriptional activator), in cooperation with Npr1 kinase <cite>Harashima08</cite>.
  
It is found in most if not all of eukaryotes except eumetazoan (i.e. fungi, plants, protists, monosiga, and sponge).
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It is found in most eukaryotes other than eumetazoa. We have seen it in fungi, plants, protists, monosiga, and sponge.
  
The family is also called as plant and fungi atypical (PFA)-DSPs <cite>Pulido07 Pulido11</cite>.
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The family is also called '''plant and fungi atypical (PFA)-DSPs''' <cite>Pulido07 Pulido11</cite>.
  
  
 
===== Reference =====
 
===== Reference =====
 
<biblio>
 
<biblio>
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#Alic pmid=11408586
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#Care pmid=15020461
 
#Pulido07 pmid=17976645
 
#Pulido07 pmid=17976645
 
#Pulido11 pmid=21409566
 
#Pulido11 pmid=21409566

Revision as of 21:02, 6 December 2014

Phosphatase Classification: Superfamily CC1: OCA

The OCA family is named after the five member genes in yeast (OCA1-5 = Oxidant-induced Cell-cycle Arrest). Yeast OCA members are involved in cell cycle arrest in response to oxidative damage[1], in telomere capping [2], in actin organization [3]. OCA3 has been shown to control intracellular localization of Gln3 (a phosphorylated transcriptional activator), in cooperation with Npr1 kinase [4].

It is found in most eukaryotes other than eumetazoa. We have seen it in fungi, plants, protists, monosiga, and sponge.

The family is also called plant and fungi atypical (PFA)-DSPs [5, 6].


Reference
Error fetching PMID 11408586:
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Error fetching PMID 17976645:
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Error fetching PMID 18845848:
Error fetching PMID 18166280:
  1. Error fetching PMID 11408586: [Alic]
  2. Error fetching PMID 18845848: [lydall08]
  3. Error fetching PMID 15020461: [Care]
  4. Error fetching PMID 18166280: [Harashima08]
  5. Error fetching PMID 17976645: [Pulido07]
  6. Error fetching PMID 21409566: [Pulido11]
All Medline abstracts: PubMed | HubMed