Difference between revisions of "Phosphatase Family OCA"
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]]: [[Phosphatase_Family_OCA|OCA]] | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]]: [[Phosphatase_Family_OCA|OCA]] | ||
| − | OCA family is named after the five member genes in yeast | + | The OCA family is named after the five member genes in yeast (OCA1-5 = Oxidant-induced Cell-cycle Arrest). Yeast OCA members are involved in cell cycle arrest in response to oxidative damage<cite>Alic</cite>, in telomere capping <cite>lydall08</cite>, in actin organization <cite>Care</cite>. [[Gene_OCA3|OCA3]] has been shown to control intracellular localization of Gln3 (a phosphorylated transcriptional activator), in cooperation with Npr1 kinase <cite>Harashima08</cite>. |
| − | It is found in most | + | It is found in most eukaryotes other than eumetazoa. We have seen it in fungi, plants, protists, monosiga, and sponge. |
| − | The family is also called | + | The family is also called '''plant and fungi atypical (PFA)-DSPs''' <cite>Pulido07 Pulido11</cite>. |
===== Reference ===== | ===== Reference ===== | ||
<biblio> | <biblio> | ||
| + | #Alic pmid=11408586 | ||
| + | #Care pmid=15020461 | ||
#Pulido07 pmid=17976645 | #Pulido07 pmid=17976645 | ||
#Pulido11 pmid=21409566 | #Pulido11 pmid=21409566 | ||
Revision as of 21:02, 6 December 2014
Phosphatase Classification: Superfamily CC1: OCA
The OCA family is named after the five member genes in yeast (OCA1-5 = Oxidant-induced Cell-cycle Arrest). Yeast OCA members are involved in cell cycle arrest in response to oxidative damage[1], in telomere capping [2], in actin organization [3]. OCA3 has been shown to control intracellular localization of Gln3 (a phosphorylated transcriptional activator), in cooperation with Npr1 kinase [4].
It is found in most eukaryotes other than eumetazoa. We have seen it in fungi, plants, protists, monosiga, and sponge.
The family is also called plant and fungi atypical (PFA)-DSPs [5, 6].
Reference
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- Error fetching PMID 18845848:
- Error fetching PMID 15020461:
- Error fetching PMID 18166280:
- Error fetching PMID 17976645:
- Error fetching PMID 21409566: