Difference between revisions of "Phosphatase Family LMWPTP"
From PhosphataseWiki
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== Function == | == Function == | ||
| − | In eukaryotes, LMWPTP | + | In eukaryotes, LMWPTP dephosphorylates many receptor tyrosine kinases, such as platelet-derived growth factor receptor (PDGFR), insulin receptor (InsR), or ephrin receptor (Eph) <cite>Kikawa02</cite>. |
In prokaryotes, the molecular function is not fully understood. It is involved in the syntheisis and translocation of exopolysaccharides (EPS) and capsular polysaccharides (CPS) in E. coli. | In prokaryotes, the molecular function is not fully understood. It is involved in the syntheisis and translocation of exopolysaccharides (EPS) and capsular polysaccharides (CPS) in E. coli. | ||
Revision as of 03:30, 1 May 2014
Phosphatase Classification: Superfamily Cys-based III: Family LMWPTP
Function
In eukaryotes, LMWPTP dephosphorylates many receptor tyrosine kinases, such as platelet-derived growth factor receptor (PDGFR), insulin receptor (InsR), or ephrin receptor (Eph) [1].
In prokaryotes, the molecular function is not fully understood. It is involved in the syntheisis and translocation of exopolysaccharides (EPS) and capsular polysaccharides (CPS) in E. coli.
Evolution
The LMWPTP is present not only in eukaryotes but also prokaryotes. In eukaryotes, it is generally absent from alveolates, trypanosoma, leishmania.
