Difference between revisions of "Phosphatase Family OCA"
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_Cys-based_I|Superfamily Cys-based I]]: [[Phosphatase_Family_OCA|OCA]] | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_Cys-based_I|Superfamily Cys-based I]]: [[Phosphatase_Family_OCA|OCA]] | ||
| − | OCA is found in most if not all of fungi, plants, protists (chromalveolata, excavata), as well as monosiga and sponge. The family is named after yeast phosphatases OCA1, OCA2, OCA3, OCA4, OCA6. OCA is short for Oxidant-induced Cell-cycle Arrest. They have been shown involved in telomere capping and uncapping <cite>lydall08</cite>. It is also called as plant and fungi atypical (PFA)-DSPs <cite>Pulido07 Pulido11</cite>. | + | OCA is found in most if not all of fungi, plants, protists (chromalveolata, excavata), as well as monosiga and sponge. The family is named after yeast phosphatases OCA1, OCA2, [[Gene_OCA3|OCA3]], OCA4, OCA6. OCA is short for Oxidant-induced Cell-cycle Arrest. They have been shown involved in telomere capping and uncapping <cite>lydall08</cite>. It is also called as plant and fungi atypical (PFA)-DSPs <cite>Pulido07 Pulido11</cite>. |
=== Reference === | === Reference === | ||
Revision as of 19:13, 27 May 2014
Phosphatase Classification: Superfamily Cys-based I: OCA
OCA is found in most if not all of fungi, plants, protists (chromalveolata, excavata), as well as monosiga and sponge. The family is named after yeast phosphatases OCA1, OCA2, OCA3, OCA4, OCA6. OCA is short for Oxidant-induced Cell-cycle Arrest. They have been shown involved in telomere capping and uncapping [1]. It is also called as plant and fungi atypical (PFA)-DSPs [2, 3].
Reference
- Addinall SG, Downey M, Yu M, Zubko MK, Dewar J, Leake A, Hallinan J, Shaw O, James K, Wilkinson DJ, Wipat A, Durocher D, and Lydall D. A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae. Genetics. 2008 Dec;180(4):2251-66. DOI:10.1534/genetics.108.092577 |
- Romá-Mateo C, Ríos P, Tabernero L, Attwood TK, and Pulido R. A novel phosphatase family, structurally related to dual-specificity phosphatases, that displays unique amino acid sequence and substrate specificity. J Mol Biol. 2007 Dec 7;374(4):899-909. DOI:10.1016/j.jmb.2007.10.008 |
- Romá-Mateo C, Sacristán-Reviriego A, Beresford NJ, Caparrós-Martín JA, Culiáñez-Macià FA, Martín H, Molina M, Tabernero L, and Pulido R. Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms. Mol Genet Genomics. 2011 Apr;285(4):341-54. DOI:10.1007/s00438-011-0611-6 |
