Difference between revisions of "Disease"
From PhosphataseWiki
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| − | == [[Disease|Phosphatases and Diseases]] | + | == [[Disease|Phosphatases and Diseases]] == |
== Cancer == | == Cancer == | ||
Revision as of 21:33, 2 June 2014
Phosphatases and Diseases
Cancer
PPM1D
PPM1D as a frequent target of somatic mutation and as a potential therapeutic target in brainstem gliomas [1].
References
- Zhang L, Chen LH, Wan H, Yang R, Wang Z, Feng J, Yang S, Jones S, Wang S, Zhou W, Zhu H, Killela PJ, Zhang J, Wu Z, Li G, Hao S, Wang Y, Webb JB, Friedman HS, Friedman AH, McLendon RE, He Y, Reitman ZJ, Bigner DD, and Yan H. Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas. Nat Genet. 2014 Jul;46(7):726-30. DOI:10.1038/ng.2995 |
