Difference between revisions of "Phosphatase Subfamily PPP1C"

Revision as of 21:38, 17 December 2014

Phosphatase Classification: Fold MTDP: Superfamily PPP: Family PPP: Subfamily PPP1C

Evolution

The PPP1Cs have many lineage-specific gene duplications. In particular, 10 PPP1Cs are found in fruit fly, while 3 in human, 3 in C. elegans, and 4 in yeast.

Functions

PPP1C also called PP1 is the catalytic subunit binding to regulatory subunits to achieve diverse functions [1]. Over 50 different regulatory subunits are known in human and at least 20 in yeast. These different complexes play key roles in various cellular processes from cell cycle progression [2] to glycogen metabolism.

References

1. Error fetching PMID 22360570: [heroes13]
2. Error fetching PMID 25487150: [grallert14]