Phosphatase Subfamily PGAM
From PhosphataseWiki
Phosphatase Classification: Fold HP: Superfamily HP (histidine phosphatase): HP, branch1 family: Subfamily PGAM
Evolution
Domain
PGAM has single domain, phosphatase domain of HP1 family.
Catalytic activity
Human has four members:
- BPGM: 2,3-bisphosphoglycerate mutase. Bisphosphoglycerate mutase is an erythrocyte-specific en- zyme catalyzing a series of intermolecular phosphoryl group transfer reactions. Its main function is to synthesize 2,3- bisphosphoglycerate [1, 2].
- PGAM1: phosphoglycerate mutase 1 (brain)
- PGAM2: phosphoglycerate mutase 2 (muscle)
- PGAM4 (aka PGAM3): phosphoglycerate mutase family member 4
