Signaling Pathway And Proteins

Adaptors

p130Cas/BCAR1

p130Cas/BCAR1 is an adaptor protein that regulates multiple signaling pathways leading to cell adhesion, migration, invasion, apoptosis, hypoxia and mechanical forces. p130Cas/BCAR1 plays a role in cell transformation and cancer progression and alterations of p130Cas/BCAR1 expression and the resulting activation of selective signalling are determinants for the occurrence of different types of human tumors.