Protein Domain GRAM

PH: GRAM

Technical notes

Profile

The GRAM domain in MTMR2 is from 74 to 185 as shown in crystal structure [1]. However, its profile in Pfam and SMART is much shorter.

References

1. Begley MJ, Taylor GS, Kim SA, Veine DM, Dixon JE, and Stuckey JA. Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome. Mol Cell. 2003 Dec;12(6):1391-402. DOI:10.1016/s1097-2765(03)00486-6 |