Difference between revisions of "Phosphatase Subfamily CDC25"
From PhosphataseWiki
(→Domain) |
(→Evolution) |
||
| Line 3: | Line 3: | ||
=== Evolution === | === Evolution === | ||
| − | CDC25 subfamily is found in a broad of eukaryotes, but absent from most if not all of plants. | + | CDC25 subfamily is found in a broad of eukaryotes, but absent from most if not all of plants. It has multiple copies in some if not many genomes. For example, human, fruit fly and C elegans have 3, 2, 4, respectively, and they do not fall into 1:1 orthologous relationship. |
=== Domain === | === Domain === | ||
Revision as of 23:37, 31 December 2014
Phosphatase Classification: Fold CC3 (Rhondanese): Superfamily CC3 (Rhondanese): Family CDC25: Subfamily CDC25
Evolution
CDC25 subfamily is found in a broad of eukaryotes, but absent from most if not all of plants. It has multiple copies in some if not many genomes. For example, human, fruit fly and C elegans have 3, 2, 4, respectively, and they do not fall into 1:1 orthologous relationship.
Domain
Human CDC25s have N-terminal regulatory domain and phosphatase domain. Due to alternative splicing, the isoforms of human CDC25s have different sequences at regulatory domain region.
