Difference between revisions of "Phosphatase Subfamily CDC25"
From PhosphataseWiki
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=== Catalytic activity and functions === | === Catalytic activity and functions === | ||
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== References == | == References == | ||
Revision as of 23:41, 31 December 2014
Phosphatase Classification: Fold CC3 (Rhondanese): Superfamily CC3 (Rhondanese): Family CDC25: Subfamily CDC25
Evolution
CDC25 subfamily is found in a broad of eukaryotes, but absent from most if not all of plants. It has multiple copies in some if not many genomes. For example, human, fruit fly and C elegans have 3, 2, 4, respectively, and they do not fall into 1:1 orthologous relationship.
Domain
Human CDC25s have N-terminal regulatory domain and phosphatase domain. Due to alternative splicing, the isoforms of human CDC25s have different sequences at regulatory domain region.
