Phosphatase Subfamily PGAM

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Phosphatase Classification: Fold HP: Superfamily HP (histidine phosphatase): HP, branch1 family: Subfamily PGAM


Evolution

Human has four members:

  • BPGM: 2,3-bisphosphoglycerate mutase [1, 2]
  • PGAM1: phosphoglycerate mutase 1 (brain)
  • PGAM2: phosphoglycerate mutase 2 (muscle)
  • PGAM4: phosphoglycerate mutase family member 4

Domain

PGAM has single domain, phosphatase domain of HP1 family.