Difference between revisions of "Phosphatase Superfamily CC1"

Revision as of 20:16, 6 December 2014

CC1 (or Cysteine-based, group 1) is the largest phosphatase superfamily. It consists of three families in human:

- Classic PTP (Protein Tyrosine Phosphatase; generally tyrosine specific)

- DSP and PTEN (Dual Specificity Phosphatases; tyr/ser/thr specific)

- Myotubularin (lipid specific).

Fungi, plants and many protists also have the OCA family.

It shares a Cys-based catalytic motif, CX5R with another two superfamilies Cys-based I and Cys-based III, but it has distinct structure from them.

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 [[Phosphatase classification]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]]
-CC1 (or Cysteine-based, group 1) is the largest phosphatase superfamily. It consists of three families in human: [[Phosphatase_Family_HMWPTP|Classic PTP]] (Protein Tyrosine Phosphatase; generally tyrosine specific), [[Phosphatase_Family_DSP_PTEN|DSP and PTEN]] (Dual Specificity Phosphatases; tyr/ser/thr specific) and [[Phosphatase_Family_Myotubularin|Myotubularin]] (lipid specific). Fungi, plants and many protists also have the [[Phosphatase_Family_OCA|OCA]] family.
+CC1 (or Cysteine-based, group 1) is the largest phosphatase superfamily. It consists of three families in human:
+- [[Phosphatase_Family_HMWPTP|Classic PTP]] (Protein Tyrosine Phosphatase; generally tyrosine specific)
+- [[Phosphatase_Family_DSP_PTEN|DSP and PTEN]] (Dual Specificity Phosphatases; tyr/ser/thr specific)
+- [[Phosphatase_Family_Myotubularin|Myotubularin]] (lipid specific).
+Fungi, plants and many protists also have the [[Phosphatase_Family_OCA|OCA]] family.
 It shares a Cys-based catalytic motif, CX5R with another two superfamilies [[Phosphatase_Superfamily_Cys-based_II| Cys-based I]] and [[Phosphatase_Superfamily_Cys-based_II|Cys-based III]], but it has distinct structure from them.