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| − | __NOTOC__
| + | ==Deprecated== |
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| − | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_Cys-based_III|Superfamily Cys-based III]]
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| − | The superfamily consists of two member families present in human [[Phosphatase_Family_LMWPTP|low molecular weight PTP (LWMPTP)]] and [[Phosphatase_Family_SSU72|SSU72]]. Although human LMWPTP and SSU72 exhibit low sequence identity (15%), the overall folds are very close to each other. The rmsd (root mean square deviation) of 1.7 Å when superimposing SSU72 (PDB ID: 3OMW) with LMWPTP (PDB ID: 1XWW) <cite>zhangy11</cite>.
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| − | The subfamily has an additional member only present in prokaryotes, arsenate reductase (ArsC). It has low sequence identity with LMWPTP and SSU72, 19% between Golden Staph ArsC (PDB ID: 1LJL) and mouse LMWPTP (PDB ID: 2P4U), 16% between Golden Staph ArsC and fruit fly SSU72 (PDB ID: 3FMV). But, ArsC has very similar structure with LMWPTP as shown in [[http://scop.berkeley.edu/sunid=52789 SCOP database]].
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| − | == Reference == | + | |
| − | <biblio>
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| − | #zhangy11 pmid=21204787
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| − | </biblio>
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