Difference between revisions of "Phosphatase Superfamily HP"

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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Superfamily_HP|HP superfamily]] (histidine phosphatase)
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_PGM|Fold PGM]]: [[Phosphatase_Superfamily_HP|Superfamily HP]] (histidine phosphatase)
  
 
Histidine phosphatase does '''not''' dephosphorylate pHis. It  is named for the catalytic histidine which is phosphorylated during catalysis <cite>Rigden</cite>. In fact, the superfamily is a large functionally diverse group of proteins. For a complete of functions characterized members in the superfamily, see Table 1 and Table S1 in <cite>Rigden</cite>). The superfamily contains two branches sharing very limited sequence similarity. The superfamily is corresponding to His_phosphatase in PFAM database, Pfam ID [http://pfam.xfam.org/clan/cl0071 CL0071]).
 
Histidine phosphatase does '''not''' dephosphorylate pHis. It  is named for the catalytic histidine which is phosphorylated during catalysis <cite>Rigden</cite>. In fact, the superfamily is a large functionally diverse group of proteins. For a complete of functions characterized members in the superfamily, see Table 1 and Table S1 in <cite>Rigden</cite>). The superfamily contains two branches sharing very limited sequence similarity. The superfamily is corresponding to His_phosphatase in PFAM database, Pfam ID [http://pfam.xfam.org/clan/cl0071 CL0071]).

Revision as of 21:06, 30 December 2014

Phosphatase Classification: Fold PGM: Superfamily HP (histidine phosphatase)

Histidine phosphatase does not dephosphorylate pHis. It is named for the catalytic histidine which is phosphorylated during catalysis [1]. In fact, the superfamily is a large functionally diverse group of proteins. For a complete of functions characterized members in the superfamily, see Table 1 and Table S1 in [1]). The superfamily contains two branches sharing very limited sequence similarity. The superfamily is corresponding to His_phosphatase in PFAM database, Pfam ID CL0071).


  1. Rigden DJ. The histidine phosphatase superfamily: structure and function. Biochem J. 2008 Jan 15;409(2):333-48. DOI:10.1042/BJ20071097 | PubMed ID:18092946 | HubMed [Rigden]