Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA ------------------------------------------------------------
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA ------------------------------------------------------------
Ddis_cnrN.AA ------------------------------------------------------------
Ddis_DDB_G0285967.AA ------------------------------------------------------------
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA MAAAGGEEALPVAPADMSDSLRLLEDAIDHYRHRHEACLAQSAGGEADPSAITVNVHPDV
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA ------------------------------------------------------------
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA ------------------------------------------------------------
Ddis_cnrN.AA ------------------------------------------------------------
Ddis_DDB_G0285967.AA ------------------------------------------------------------
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA QVQLNREDESTVRLANGTVIQHRYACLDRRVSFPTVLLLLSLYRIDCSSRIVNLASTRQS
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA ------------------------------------------------------------
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA ------------------------------------------------------------
Ddis_cnrN.AA ------------------------------------------------------------
Ddis_DDB_G0285967.AA ------------------------------------------------------------
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA LSHRSLPSSFNGTKIVSLPDGTVVEILLDGTRYIRNARTGTILTETADGAQSVSNPAQTP
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA ----------------------------------------------MVTPPPDVPSTSTR
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA ------------------------------------------------------------
Ddis_cnrN.AA ------------------------------------------------------------
Ddis_DDB_G0285967.AA ------------------------------------------------------------
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA LHKPEKRVGFGSLAPLLEKQQMYASTTNNAEHTGTAQSPALDSTTNASASPSPSPSKGTT
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ------------MREEGSELEMEKGFLKWKP-----------------------------
Ddis_DDB_G0275865.AA --MDFLKKLNQDLIKKSNELGEEINKQVNST-----------------------------
Cele_daf-18.AA SMARDLQENPNRQPGEPRVSEPYHNSIVERI-----------------------------
Ddis_DDB_G0292920.AA -------------------------MSDGSG-----------------------------
Ddis_DDB_G0289979.AA --------------------------MYNSI-----------------------------
Ddis_cnrN.AA --------------------------MNQVF-----------------------------
Ddis_DDB_G0285967.AA ------------------------------------------------------------
Dmel_Pten.AA -----------------------MANTISLM-----------------------------
Mbre_mbre_PTEN-A.AA ASASAMDRSAVEEPDEDQDASLDEPDSEDDVDSSSDEEEIDRKPSLPDAASAASVVEHDN
Ddis_pten.AA ------------------------------M-----------------------------
Mbre_mbre_PTEN-B.AA ------------------------------M-----------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA -----------------------------MA-----------------------------
Hsap_PTEN.AA ------------------------------M-----------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA ------------------------------------------------------------
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA ------------------------------------------------------------
Ddis_cnrN.AA ------------------------------------------------------------
Ddis_DDB_G0285967.AA ------------------------------------------------------------
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA VIHQGWLFKEGGQIRSWRRRYFVLQSNGLLVYFPDAPQASGRNSTPINAIDVVGAEVTQS
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA ------------------------------------------------------------
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA ------------------------------------------------------------
Ddis_cnrN.AA ------------------------------------------------------------
Ddis_DDB_G0285967.AA ------------------------------------------------------------
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA TSSKRPHGFIVASDQSAKRRSSATNKREKYVLAGSSDADRDAWMARIRYCAALDSQSLDG
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA -----------------------VNLMKKILSLPM--KKTKND-IGLRLDISYILVNLIV
Ddis_DDB_G0275865.AA -----------------------VLKIRTQVSENNTTIRFKDG--EFDLDLSYITERIIA
Cele_daf-18.AA -----------------------RHIFRTAVSSNR--CRTEYQ--NIDLDCAYITDRIIA
Ddis_DDB_G0292920.AA -----------------------FDYFRTIVSGRK--KRFIQD--GFNLDLSYITERILA
Ddis_DDB_G0289979.AA -----------------------VKAVRKTISADK--NRYENE--EYDLDLTYITERVIA
Ddis_cnrN.AA -----------------------FSKIRSLVSADR--HRFKSKEMDLDLDLSYITDNILA
Ddis_DDB_G0285967.AA -----------------------MDLVRKMVSKKK--RRFEMY--NFDLDLSYITDRVIA
Dmel_Pten.AA -----------------------SNVIRNVVSKKR--IRYKEK--GYDLDLTYINDNIIA
Mbre_mbre_PTEN-A.AA TILPVAQHSLASRFTNFARGINASNKVRQLVSKQK--IRFQKD--GFDLDLTYITPNIVA
Ddis_pten.AA -----------------------SNLLRVAVSKQK--RRYQKN--GYDLDLAYITDNIVA
Mbre_mbre_PTEN-B.AA -----------------------ATIAKHLVSKKK--RRFMDE--GFDLDLTFITRNIVA
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA -----------------------MSYFKQLVSKKK--RRFQED--GFDLDLTYIKPNIVA
Aque_aque_PTEN.AA -----------------------TNKFRHLVSKRK--RRFIAD--GFDLDMTFIKPNIVA
Hsap_PTEN.AA -----------------------TAIIKEIVSRNK--RRYQED--GFDLDLTYIYPNIIA
Spur_spur_PTEN-B.AA -----------------------------MVSKKK--RRFIDK--GFDLDLSYIYPNIIA
Scer_TEP1.AA CSYPVNTYP--KLLYRNSLDDLILFLTVYHGKGNFRIFNFRGEKEDSDYKDNDLIGIAAK
Ddis_DDB_G0275865.AA MSFPSEDTVINSTWYRNSRVDVKKMLDKYH-RDHYLIINL-TEK---------------S
Cele_daf-18.AA IGYPA-TGI--EANFRNSKVQTQQFLTRRHGKGNVKVFNLRGGY---------------Y
Ddis_DDB_G0292920.AA MGYPA-DSI--HKAFRNDINEVYNFFEKYH-SAHWKILNVAMEI---------------S
Ddis_DDB_G0289979.AA MSFPA-DGV--ESAYRNSIYDVSKLLNTSH-KDHYLIYNL-SER---------------K
Ddis_cnrN.AA MGFPG-TGL--EASWRNSIDDVCELLKQKH-HGKYMIWNL-SER---------------V
Ddis_DDB_G0285967.AA MGFPS-ESL--EGLYRNRMRDVQRFFNTLH-ADHYKVYNLCSER---------------K
Dmel_Pten.AA MGYPAPDKL--EGLFRNRLEDVFKLLEENH-AQHYKIYNLCSER---------------S
Mbre_mbre_PTEN-A.AA MGYPA-EGT--EAVYRNRYEDTLRFLEERH-PGAYRVYNLCSER---------------A
Ddis_pten.AA MGFPS-EKV--EGVFRNPMKDVQRFLDQYH-KDHFKVYNLCSER---------------V
Mbre_mbre_PTEN-B.AA MGFPA-EGR--EGIYRNHMRDVKRFFDYRC-KDHYRVYNLCSER---------------D
Spur_spur_PTEN-A.AA MGFPA-ESL--ERMYRNDMEHVVKFLNSHH-QDHYKVYNLCSER---------------N
Nvec_nvec_PTEN.AA MGFPS-EKL--EGVYRNHMDEVYRFLEQKH-KDSYKVYNLCSER---------------Q
Aque_aque_PTEN.AA MGFPS-EKL--EGVYRNKMSDVQRYFDTHY-TDHYKVYNLCSER---------------F
Hsap_PTEN.AA MGFPA-ERL--EGVYRNNIDDVVRFLDSKH-KNHYKIYNLCAER---------------H
Spur_spur_PTEN-B.AA MGFPA-ESL--EGVYRNKLEVVVKFFNEKH-GERYKVYNLCSER---------------N
.:* :** : : *.
Scer_TEP1.AA FESKDFEIQELRSTLINDGKIPIS-PIDLETRTLVEEETNNVICERIGWLDHFPPPFELL
Ddis_DDB_G0275865.AA YDSSFF-----------GGRVHHI-GCV----------------------DNHSPSLGLL
Cele_daf-18.AA YDADNF-----------DGNVICF-DMT----------------------DHHPPSLELM
Ddis_DDB_G0292920.AA YSTTKV-----------GGNVIVM-GFE----------------------DHTPPPFLLL
Ddis_DDB_G0289979.AA YDYSLF-----------NGMVLDWCGFP----------------------DHHAPPLGLL
Ddis_cnrN.AA YDYSKL-----------NNQILEF-PFL----------------------DHHPPPLSLL
Ddis_DDB_G0285967.AA YEHCRF-----------EDRVSEY-PFD----------------------DHCPPTLNII
Dmel_Pten.AA YDVAKF-----------RGRVAVY-PFD----------------------DHNPPTIELI
Mbre_mbre_PTEN-A.AA YPPSRF-----------HNRVGVY-PFD----------------------DHNPAPLPLV
Ddis_pten.AA YDHSKF-----------YGRVGYY-PFD----------------------DHNAPQFEMI
Mbre_mbre_PTEN-B.AA YDPQKF-----------YGRVAKY-PFD----------------------DHNAPPFLLM
Spur_spur_PTEN-A.AA YDTSRF-----------DHRVAHY-PFD----------------------DHNPPRIELI
Nvec_nvec_PTEN.AA YDPMRF-----------HNRVATY-PFD----------------------DHNAPPFELI
Aque_aque_PTEN.AA YDPKKF-----------H-KVTVY-PFD----------------------DHNPPPFELI
Hsap_PTEN.AA YDTAKF-----------NCRVAQY-PFE----------------------DHNPPQLELI
Spur_spur_PTEN-B.AA YDTTKF-----------YNRVAHY-PFD----------------------DHNPPRLELI
: . : *: .. : ::
Scer_TEP1.AA EEIVDGIENYLSVSKN-RVAVLHCRMGKGRSGMITVAYLMKYLQCPLGE----------A
Ddis_DDB_G0275865.AA LYAVQVIHKWLSEDPK-NVVAIHCLAGLGRSGTLIVAYLLTSLYEGRKE----------E
Cele_daf-18.AA APFCREAKEWLEADDK-HVIAVHCKAGKGRTGVMICALLIYINFYPSPR----------Q
Ddis_DDB_G0292920.AA LDIIETMNKWLDSDEQ-NVIAVHCKAGKGRTGTVISSYLINQMKRTTPDLFYSSDTILYN
Ddis_DDB_G0289979.AA FKIVMTIYSWLEKDPM-NVVVVHCMAGKGRTGTVISALLQYGGLFEGAS----------D
Ddis_cnrN.AA FEIVNSLSNWLKADAE-NVAVVHCKGGKGRTGTIICCYLYYSCQFEIMD----------D
Ddis_DDB_G0285967.AA SEFCNDMEMWLDQNPE-NVVAVHCKAGKGRTGTMLACWLLYNKQCQTGS----------E
Dmel_Pten.AA QRFCSDVDMWLKEDSS-NVVAVHCKAGKGRTGTMICAYLVFSGIKKSAD----------E
Mbre_mbre_PTEN-A.AA LACCADIHAWLAANPERNVAAIHCKAGKGRTGLIISCYLMYAGICPDPD----------S
Ddis_pten.AA DAFCRDVDAWMKEDSK-NIAVIHCKAGKGRTGLMICCWLMYCGMWKNTE----------D
Mbre_mbre_PTEN-B.AA QPFCEDVHQYLSEDSR-NVAVIHCKAGKGRTGVMISAYLMHCGLFEKTE----------E
Spur_spur_PTEN-A.AA RPFCEDVMQWLAEDKD-NVAAIHCKAGKGRTGVMICALLLHQGRCLTAA----------E
Nvec_nvec_PTEN.AA KPFCDDVDEWLKASNL-NVAIIHCKAGKGRTGVMICAYLLHNGHFKDTK----------E
Aque_aque_PTEN.AA QPFCEDVDGWLKEDNR-NVAVIHCKAGKGRTGVMICSYLLHDRLFDTVK----------D
Hsap_PTEN.AA KPFCEDLDQWLSEDDN-HVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQ----------E
Spur_spur_PTEN-B.AA KPFCEDLDNWLGADGQ-NVAAIHCKAGKGRTGVMICAYMLHRRLYQTAS----------E
:: . .: :** * **:* : . :
Scer_TEP1.AA RLIFMQARFKYGMTNGVTIPSQLRYLRYHEFFIT--HEKAAQE---GISNEAVKFKF---
Ddis_DDB_G0275865.AA ALQLFASQ-RTTSKVGVKVPSQLRYIDYVHQLVTSQRPVDVVQNPMKLRLNAIMIKPSP-
Cele_daf-18.AA ILDYYSII-RTKNNKGVTIPSQRRYIYYYHKLRE--RELNYLP-L-RMQLIGVYVERPPK
Ddis_DDB_G0292920.AA TISFFNQM-RANNSECVTVPSQKRYVGYYIQYLR--DQVTHASLLSPAQFKILNIDVIG-
Ddis_DDB_G0289979.AA AMRYFAVK-RSNNNYGITGPSQIRYTQYFSDIYF--GGKELNP-G-PVFLKSISMVTLP-
Ddis_cnrN.AA AKNHFAEK-RSKMKKGVTQPSQQRYINYFKEIVS--GSHMVEE-F-VLTFRSIELGPLTK
Ddis_DDB_G0285967.AA SMRLFANK-RTHNSKGVTIPSQIRYVRYFEALLQYGKPIPKPPSI-TKVLSMIKMNSLP-
Dmel_Pten.AA ALAWYDEK-RTKDRKGVTIPSQRRYVQYFSKLVC--SSVPYSK-V-SLNVCEIRFSESS-
Mbre_mbre_PTEN-A.AA AMTMFGAK-RTHNGKGVTIPSQRRYIRYFHTMLQ--GDRTVPPAT-PLTLTGIRLHGVP-
Ddis_pten.AA SLRFYAAL-RTYNQKGVTIPSQIRYVGYFGRSIR--ESIKYVP-R-NVTLKKIVLRPLPK
Mbre_mbre_PTEN-B.AA ALEFYGHA-RTMNGKGVTIPSQVRYVHYYGRYVR--EQREFEP-I-PLIMKRIILHGIP-
Spur_spur_PTEN-A.AA SMEYYGKI-RTTDGKGVTIPSQRRYVQYYGELVK--RNTLYKT-Q-TVLLKRVQLYTIP-
Nvec_nvec_PTEN.AA AMEYYGNA-RTRNAKGVTIPSQRRYVEYYGYLLR--NCLTYVP-T-MVLLRGFEIITIP-
Aque_aque_PTEN.AA ALQFYGEA-RTQNAKGVTIPSQRRYVQYYGHLIR--NNLQYSP-R-TILLHAIRLEGIP-
Hsap_PTEN.AA ALDFYGEV-RTRDKKGVTIPSQRRYVYYYSYLLK--NHLDYRP-V-ALLFHKMMFETIP-
Spur_spur_PTEN-B.AA ALDFYASK-RTKNRKGVTIPSQRRYVEYYGNLIV--RELEYKP-T-TLLLTRIDLETVP-
. :. *** ** * . .
Scer_TEP1.AA ---------KFRLA----KMTFLRPSSLITSESAIVT--TKIQHYNDDRNALLTRKVVYS
Ddis_DDB_G0275865.AA ---------VVS------GKSGQVWKPTIEI-FNVMKPLEPHLLFSTKDLDGPFNKNQ--
Cele_daf-18.AA TWGGGSKI-KVEVGN---GSTILFKPDPLIISKSNHQ--RERATWLNNCDTPNEFDTGEQ
Ddis_DDB_G0292920.AA ---------LYT------STQTPHFNIEIHLNYNPKI--RNLPIIIRGSNTGIVF-----
Ddis_DDB_G0289979.AA ---------KFFLGPLKQGVCPVLNI------YSATQ--KGVRIFTSAPIEGDTKETRTY
Ddis_cnrN.AA DQANSLSFEIFEHA----KEPILN--------FASSSNSIQIVPINNDNSESNNNNNNNN
Ddis_DDB_G0285967.AA ---------NFNIG----GGCEPY--------LSIVQ--QGKSVFYSKPVKLKK------
Dmel_Pten.AA --------------------CVQN--------LGMVE--CSISVLHDSATENAKPDRLKT
Mbre_mbre_PTEN-A.AA ---------NYDFS----GGCQPY--------YQVYQ--EGVLIFSSKPAELRQLQAYK-
Ddis_pten.AA EINLSEVQFNIS-V----GKNCVFNSKEHNMNVVISK--KKKTVVDKNKKDPKKKLTKEN
Mbre_mbre_PTEN-B.AA ---------DFK-D----GTCVPQ--------FTLRHGPQHVLTFKSGWYEGISR-----
Spur_spur_PTEN-A.AA ---------MMS-S----GTCCPF--------FTVHQ--HKVKIHTQEAVKGVKK-----
Nvec_nvec_PTEN.AA ---------NMQ-G----GNCCPF--------YIIWQ--YKVKIHTSKLIESSKK-----
Aque_aque_PTEN.AA ---------NFS-G----GTCAPF--------FIVRK--HKVVLYTSKVYESIRR-----
Hsap_PTEN.AA ---------MFS-G----GTCNPQ--------FVVCQ--LKVKIYSSNSGPTRR------
Spur_spur_PTEN-B.AA ---------MFN-G----GSCAPA--------FVIYQ--QKVKIFSSQPYEVAK------
Scer_TEP1.AA DIMAHE------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA KYHGFVS-----------------------------------------------------
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA ------------------------------------------------------------
Ddis_cnrN.AA NNNNNNNNQ---------------------------------------------------
Ddis_DDB_G0285967.AA ------------------------------------------------------------
Dmel_Pten.AA LPIDF-------------------------------------------------------
Mbre_mbre_PTEN-A.AA ------------------------------------------------------------
Ddis_pten.AA SEKNIDSQQQQQSQSSLSQSQQGQSSPNMQSLSASGTISSGSNVGTVNGNTLHQLGGSQF
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ------------CGGNMT-----FIFGRDYLTLENDCRIEFTLG----------TSKSKA
Ddis_DDB_G0275865.AA ------------NDAFCKVQGDVVIIETQSLVLQGDVLVKIYHGFSDILSKEVLNVIMDK
Cele_daf-18.AA ------------KRAYCF-----MVPEDAPVFVEGDVRIDIREI---------GFLKKFS
Ddis_DDB_G0292920.AA ------------YQDFYS-----YILREKGIIAKGDTLIKFNSL--------------DS
Ddis_DDB_G0289979.AA ------------QSGNAT-----IVFEV-RKIVRGDILLVFSHI-----TPFYRVEQICR
Ddis_cnrN.AA ------------QQQLYK-----IIILI-QKKVQNDVLIRVYRG-----DTGKGKGKMKK
Ddis_DDB_G0285967.AA ------------GTIHQQ-----VELDCGNILLVNDVQIQFFNR--------------NS
Dmel_Pten.AA ------------QKSFV------LTIKP-SIPVSGDVKFELTKK--------------SP
Mbre_mbre_PTEN-A.AA ------------RQTHRD-----IRFSC-NMAIEGNIRIELWDC--------DRGFHSEE
Ddis_pten.AA SLSDLADGNTIGNDEYIS-----FEIG--ALSLAGDIRIEFTNK-----Q--------DD
Mbre_mbre_PTEN-B.AA ------------EQGTAT-----LELKP-HTPVCGDVKLEFIHR---------KGSSGKE
Spur_spur_PTEN-A.AA ------------GLSCVE-----FELPH-ALPIRDDVKIEFYHK---------SGLLKMD
Nvec_nvec_PTEN.AA ------------GDTSIK-----LELSQ-PLPICGDIKVEFFHK---------DTFGRKE
Aque_aque_PTEN.AA ------------TDAFAE-----LMLTK-PIPLCDDIKVEFYHN-----PRFGSKASYTE
Hsap_PTEN.AA ------------EDKFMY-----FEFPQ-PLPVCGDIKVEFFHK--------QNKMLKKD
Spur_spur_PTEN-B.AA ------------KERSVR-----CEFPL-PVPICGDIKIEFFNK---------PNKLKKD
.: . .
Scer_TEP1.AA ASSIIS----WTSCASC-------------------------------------------
Ddis_DDB_G0275865.AA P--SLR---LAFHTSFIDN-----------------------------------------
Cele_daf-18.AA DGKIGH---VWFNTMFACDGGLNGGHFEYVDKTQPYIGDDTSIGRKNGMRRNETPMRKID
Ddis_DDB_G0292920.AA PQCVFR---FLFHTSFLLTPT---------------------------------------
Ddis_DDB_G0289979.AA A--NFHTGMFSFPTLILTKSDLDGADGDKRFSSDFHLRLDFQEVVNQNQQQQQQLLNSNN
Ddis_cnrN.AA Q--IFH---LIFNIAFVNLDQCLFGM----------------------------------
Ddis_DDB_G0285967.AA KGHMFS---YCFHTAFIEGTKIHIRRQEIDKAHKDLKHFHSNFSIELIFLEDDRDDDSSS
Dmel_Pten.AA DKIICH---FWLNTFFVRN-----------------------------------------
Mbre_mbre_PTEN-A.AA K--MFA---ATFFTGMVEGTS---------------------------------------
Ddis_pten.AA R--MFM---FWVNTSFVQ------------------------------------------
Mbre_mbre_PTEN-B.AA K--MFH---LWFNTFFIVN-----------------------------------------
Spur_spur_PTEN-A.AA KRLMFH---MWFNTYFIVHPIQP-------------------------------------
Nvec_nvec_PTEN.AA R--MFQ---FWFNTFFISTGA---------------------------------------
Aque_aque_PTEN.AA K--MFL---FWFNTFFVDW-----------------------------------------
Hsap_PTEN.AA K--MFH---FWVNTFFIPGPE---------------------------------------
Spur_spur_PTEN-B.AA R--MFH---FWFNTFFVANSNLL-------------------------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA PETGNEFESPWQIVNPPGLEKHITEEQAMENYTNYGMIPPRYTISKILHEKHEKGIVKDD
Ddis_DDB_G0292920.AA --------------------------------------TQDSQSI---------------
Ddis_DDB_G0289979.AA GDLTPYIIPANAQTSIEYQKEIKKEIKWIRHEAIAKKDHRNGSIFFLPSNNSEKIKQAKD
Ddis_cnrN.AA --------------------------NEFDHFKSSKKYDPNLQMEC--------RFQNNC
Ddis_DDB_G0285967.AA VSEESVEEKRVFNTSYATGLAKLYHNSNSNNKSLTSSTSSTSNLSSSTNNTFEIISNNNN
Dmel_Pten.AA ----------------------------------YSPCESDGTVNK--------------
Mbre_mbre_PTEN-A.AA ------------------------------------------------------------
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA --------------------------DKDYFGQARSHSRPTSTVSCPSPDQARAPFAEDE
Nvec_nvec_PTEN.AA ------------------------------NMTDSREGEPTIHTFKESRNSDV-------
Aque_aque_PTEN.AA --------------------------HVMQQEAQNAMATNSLSVSWLYTASHF-------
Hsap_PTEN.AA --------------------------ETSEKVENGSLCDQEIDSICSI-----------E
Spur_spur_PTEN-B.AA --------------------------NSSSQQDLANNGSSDNSSHCSEDNMEALDADC--
Scer_TEP1.AA --------------------------------------WLNIYLETLMHI--IKDDSS--
Ddis_DDB_G0275865.AA -------------------------------------HCLDLNRSTLDEK--DNCIQS--
Cele_daf-18.AA YNDRKLPMGDKSYTESGKSGDIRGVGGPFEIPYKAEEHVLTFPVYEMDRALKSKDLNNGM
Ddis_DDB_G0292920.AA -------------------------------------ITLYFQKDNLDGG--SGGAFLD-
Ddis_DDB_G0289979.AA TASKQGTFGVHSGYLFKKGHNFKSW----------RRRWFVLKDNILSYY--KSPKDTAP
Ddis_cnrN.AA TGAPDHSF-----------------------------KIWNIMALQYQRT--KSSLNNSI
Ddis_DDB_G0285967.AA NNNNNNNN-----------------------------NNINSNNNKINDE--NSNKNNNN
Dmel_Pten.AA -------------------------------------YIHTLSKSEIDDV--HKDSEH--
Mbre_mbre_PTEN-A.AA ---------------------------------------LRMVRQELDGA--HKKKHL--
Ddis_pten.AA -------------------------------------QLEIIPKSGLDKA--HKDKNH--
Mbre_mbre_PTEN-B.AA -------------------------------------NRFYAAQSEVDKA--NKDKKN--
Spur_spur_PTEN-A.AA MLNGGEE------------------------------FVLELHKDEIDKA--NKDKTN--
Nvec_nvec_PTEN.AA -------------------------------------RWFAIPKQFVDKA--HKDNKC--
Aque_aque_PTEN.AA -------------------------------------RVVILPKNEIDKA--NKDKKH--
Hsap_PTEN.AA RADNDKEY-----------------------------LVLTLTKNDLDKA--NKDKAN--
Spur_spur_PTEN-B.AA -------------------------------------TVLRLQKDQLDRA--NKDKTN--
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA KLHVVLRCVDTRDSKMMEKSEVFGNLAFHNESTRRLQALTQMNPKWRPEPCAFGSKGAEM
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA AGIIPINEIVNIEIECEISQAEGYDYCFQISTSKANYLISAENERDLEDWTEILRSAKRM
Ddis_cnrN.AA TDIKSINEINSTNNNNILASSAPTPLTTTTTTTTTTTTTSLPSS----------------
Ddis_DDB_G0285967.AA NNIINNNSFSAWGNNSKIVKNRGSKLAFICPKCNLPITATDPSINRNSENYHWKCVVCVK
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA ------------------------------------------------------------
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA HYPPSVRYSSNDGKYNGACSENLVSDFFEHRNIAVLNRYCRYFYKQRSTSR---------
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA VQSTGRLFIEILEVKYQPNMILADRSFINNPQPNGVLPLPIKMLDINDHPIDIITYVTVH
Ddis_cnrN.AA ------------------------------------------------------------
Ddis_DDB_G0285967.AA CSKPLGGESDCVFENNEMLCTDCGTEFFKSCSGCNLVIKTSDFEELGDHIYHRSCFLCYY
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA ------------------------------------------------------------
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ----------------------PDY-----------------------------------
Ddis_DDB_G0275865.AA ------------------DKFSQDFSLR--------------------------------
Cele_daf-18.AA ------------------SRYPRKFRYC--------------------------------
Ddis_DDB_G0292920.AA ------------------SKYKTDFAIR--------------------------------
Ddis_DDB_G0289979.AA LGKKRDTTSHKSVLYNPVFMYAGDFPIY------DDEPSDL-------------------
Ddis_cnrN.AA ------------------EHSTPQILIS--------------------------------
Ddis_DDB_G0285967.AA CTSYLGGKDFIVENINNIRRFKCSSCIDNKNRQNGDDDDNNNNDNIENILENKIPEICDK
Dmel_Pten.AA ------------------KRFSEEFKIS--------------------------------
Mbre_mbre_PTEN-A.AA ------------------KMFEPQFAME--------------------------------
Ddis_pten.AA ------------------KAFPEDFHVE--------------------------------
Mbre_mbre_PTEN-B.AA ------------------KIYPEGFAIE--------------------------------
Spur_spur_PTEN-A.AA ------------------KVFSPNLKVK--------------------------------
Nvec_nvec_PTEN.AA ------------------KVFSPDFKVS--------------------------------
Aque_aque_PTEN.AA ------------------KQYPCNFKVH--------------------------------
Hsap_PTEN.AA ------------------RYFSPNFKVK--------------------------------
Spur_spur_PTEN-B.AA ------------------KWYSPNFKVI--------------------------------
Scer_TEP1.AA ---------------------------FQVERLKRDEMLGT-------------------
Ddis_DDB_G0275865.AA ---------------------------LLFSPYQEQQQQPQPLQ----------------
Cele_daf-18.AA ----------------------PLIKKHFYIPADTDDVDENGQPFFHSPEHYIKEQEKID
Ddis_DDB_G0292920.AA ---------------------------VLLEPILSNNISNNNNYNN--------------
Ddis_DDB_G0289979.AA -------VVSLWVRSSVQNIKDTLAAEFILKHNQLTNKYNTDWRDFNRIKSNLLSKMSLK
Ddis_cnrN.AA ----------------------SSDANLDLKNCNINCDSSSGGGSN--------------
Ddis_DDB_G0285967.AA LDKEIIKLVIEIDKSTEPSPVSSIDPSMIFNDLEDNGKRRQMTVESMICSKCELAINQSR
Dmel_Pten.AA ---------------------------IVFEAENFSNDVQA-------------------
Mbre_mbre_PTEN-A.AA ---------------------------LTFKS----------------------------
Ddis_pten.AA ---------------------------LTFDQLDQQQSHTTVVASA--------------
Mbre_mbre_PTEN-B.AA ---------------------------ILFDNPEGNAKTSSPLAAN--------------
Spur_spur_PTEN-A.AA ---------------------------LFFARGREDQVPPT-------------------
Nvec_nvec_PTEN.AA ---------------------------NVF------------------------------
Aque_aque_PTEN.AA ---------------------------MVLSEADNPGFSLD-------------------
Hsap_PTEN.AA ---------------------------LYFTKTVEEPSNPE-------------------
Spur_spur_PTEN-B.AA ---------------------------CYFKRVENEKPRRP-------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA AEKAAKGIENTGPSTSGSSAPGTIKKTEASQSDKVKPATEDELPPARLPDNVR-------
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA IGMAYGSEVDIQLSEIAKGSSQQQQQQSSSSLSASPSSSPHTSTNYLNNKPHVSFNHS--
Ddis_cnrN.AA ------------------------------------------------------------
Ddis_DDB_G0285967.AA PIILDCGIYHRECFQCSECFDETPMDPSLYYIRNDKPVCFDCDVNHIMNEAHSEITCYGC
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA ------------------------------------------------------------
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA ------------------------------------------------------------
Cele_daf-18.AA ------------------------------------------------------------
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA ------------------------------------------------------------
Ddis_cnrN.AA ------------------------------------------------------------
Ddis_DDB_G0285967.AA KLPIVDEVMMDALNFKWHVACLVCSKCAIQIEGQLGDHQGLIYCKDHFEELVGTKCDQCN
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA ------------------------------------------------------------
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA -----------------------------------PLQPQQYQPANYQLPQQFQQPQQQQ
Cele_daf-18.AA --------------------------RFPVVGVDFENPEEESCEHKTVESIAGFEPLEHL
Ddis_DDB_G0292920.AA ---------------------------------NNNNNNNSIENNNGVVLRKAPLPPVIS
Ddis_DDB_G0289979.AA -------IYNNSNILSANSNS-----ISLSNSLNFNTTPSSSTTTTTTTATNSNVSTSLP
Ddis_cnrN.AA --------------------------SSRNSNSNSRGGSSNSSSNRSSTSSRSSITTDSI
Ddis_DDB_G0285967.AA QYIDGMFLKVNGKNLCPTCFRCFCCNEVLEGGKYFEKNGESICEKCRNEDILKRKTQIHI
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA ------------------------------------------------------------
Ddis_pten.AA --------------------------EEQTNNQHYPQSSNNVATSSSHHDNITVVASDAP
Mbre_mbre_PTEN-B.AA ---------------------------------------------------SLSASTASA
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA QPQHFQQSQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQYQPPQQ-SQPQ----
Cele_daf-18.AA FHESYHPNTAGNMLRQDYHTDSEVKIAEQEAKAFVDQLLNGQGVLQEFMKQ-FKVPSDNS
Ddis_DDB_G0292920.AA NNTNFFDNNNNNNNSFNNSNNNNFNININNCNGNSIQPHVQQAPPPPVPCR-SKKP----
Ddis_DDB_G0289979.AA QPSTIYLAKSREENKINNLNSSNNSNTSVNSNLSRDPLTGLPTVNNNNGKQ-NESN----
Ddis_cnrN.AA KPSCSSDSICNNSSICNNSCNNNNNNNNNNNNNNNNNNNNNNNNNNNKNSN-NNNN----
Ddis_DDB_G0285967.AA QHTLITSLKNSQQISEKSSSSLSTSSTTTTTTTNNVVSSTSSTSTSPSTSP-SNSPLSSS
Dmel_Pten.AA ------------EASEKERNENVLNFERSDYDSLSPNCYAEKKVLTAIVND-NTTK----
Mbre_mbre_PTEN-A.AA ------------------------------------------------------------
Ddis_pten.AA QNNNNNNNLNSSNSNNATTTTTKNNISLASSQSNPVQQESNPSTTTQVSEE-NSAP----
Mbre_mbre_PTEN-B.AA QGMVPTASDGSDPAIPATSRGGQPMLPSRGPDASGEPLSAIPGKLTHRDSNVSQAP----
Spur_spur_PTEN-A.AA -------------------------------------PEPSEGNLSPSQSENDLLD----
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA -------------------------------------HYCEEDLESQTDEQ-PDDP----
Hsap_PTEN.AA --------------------------------------ASSSTSVTPDVSD-NEPD----
Spur_spur_PTEN-B.AA ---------------------------------------SGDSNDRSSGTS-SDHE----
Scer_TEP1.AA ---------------------TISWQELDGFGELST------------------------
Ddis_DDB_G0275865.AA ---------------------HFQQQPPPQYQPPQQYQPPQQYQQPQPYQPQPQQYQQQQ
Cele_daf-18.AA FADYVTGQAEVFKAQIALLEQSEDFQRVQANAEEVDLEHTLGEAFERFGHVVEESNGSSK
Ddis_DDB_G0292920.AA ---------------------IYSYEPYEL------------------------------
Ddis_DDB_G0289979.AA ---------------------KFGYNPYDEDDEDK-----------LIEALQSQLNDTED
Ddis_cnrN.AA ---------------------ESSSNSNDDSDSEASIRKRKNTLWSSGSSIKLKPSPNLS
Ddis_DDB_G0285967.AA IQKDAPLFCLNKSRSLFRNSIKIHLEDLKNSGERK------TLLYPSFHRQMRKQTFKTA
Dmel_Pten.AA ---------------------SQTIETLDHKDIVV-------------------------
Mbre_mbre_PTEN-A.AA ------------------------------------------------------------
Ddis_pten.AA ---------------------KVEAEKIENSNASA-------------------------
Mbre_mbre_PTEN-B.AA ---------------------EFSDSDLTTTDEDD-------------------------
Spur_spur_PTEN-A.AA ---------------------DQDLDDGTDSGDED-------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ---------------------HHGEENLSDTDPEDD------------------------
Hsap_PTEN.AA ---------------------HYRYSDTTDSDPEN-------------------------
Spur_spur_PTEN-B.AA ---------------------HSDGGDISETDSE--------------------------
Scer_TEP1.AA ------------------------------------------------------------
Ddis_DDB_G0275865.AA PP----------------------------------------------------------
Cele_daf-18.AA NPKALKTREQMVKETGKDTQKTRNHVLLHLEANHRVQIERRETCPELHPEDKIPRIAHFS
Ddis_DDB_G0292920.AA ------------------------------------------------------------
Ddis_DDB_G0289979.AA DEDLLLSTLKNKLDDFDDEDGGDDY------------------------NNNNSTTRVLE
Ddis_cnrN.AA RLSLFNGHRQSFTKKINPNNNEENV------------------------DQKTLPILKKE
Ddis_DDB_G0285967.AA YPSLRGTRRKDFLNHSKNELDSSNN------------------------SLSTLVNAFVP
Dmel_Pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-A.AA ------------------------------------------------------------
Ddis_pten.AA ------------------------------------------------------------
Mbre_mbre_PTEN-B.AA ------------------------------------------------------------
Spur_spur_PTEN-A.AA ------------------------------------------------------------
Nvec_nvec_PTEN.AA ------------------------------------------------------------
Aque_aque_PTEN.AA ------------------------------------------------------------
Hsap_PTEN.AA ------------------------------------------------------------
Spur_spur_PTEN-B.AA ------------------------------------------------------------
Scer_TEP1.AA -HGLKLFQALKLEWEII
Ddis_DDB_G0275865.AA -QQQSPNLQKQNNQYNM
Cele_daf-18.AA ENSFSDSNFDQAIYL--
Ddis_DDB_G0292920.AA -----------------
Ddis_DDB_G0289979.AA DDNISEFEEIRDSQNSN
Ddis_cnrN.AA TNDPSESDIKNVEIIQD
Ddis_DDB_G0285967.AA PQQSNNSNTTTTTNTST
Dmel_Pten.AA -NQHTCNQCLLRTYNSW
Mbre_mbre_PTEN-A.AA -----------------
Ddis_pten.AA -NDSETSSNSSS-----
Mbre_mbre_PTEN-B.AA -DEWEGLPISDV-----
Spur_spur_PTEN-A.AA -CIYETSESSVV-----
Nvec_nvec_PTEN.AA -----------------
Aque_aque_PTEN.AA -ENWEEVESVAV-----
Hsap_PTEN.AA -EPFDEDQHTQITKV--
Spur_spur_PTEN-B.AA -SEWDVTEITHV-----