Gene PPP5C-1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP5C
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP180_AA protein Get Run
AqueP180_AA_5-63 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 1-62 1.6e-10 33.9 In-house 92-154 (284) alignment 
Range on Protein: 1-62
Range on HMM: 92-154/284.0
FTFCVVHVNYLIF-LGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
|.. ... . ...  ||||   .|. |||  | ||.|  .. . |   || .||. |...|..
fayklllpdkvfllrgnhesrpvnmqygfyleckkrysealyeafqlafnamplcavvskkii
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 1-62 1.6e-08 27.3 In-house 81-144 (284) alignment 
Range on Protein: 1-62
Range on HMM: 81-144/284.0
FTFCVVHVNYL-IFLGNHELITMNQMYGFEGEVKKKYNGK-MADLFTEVFNWLPLAHVIDNKVL
|.. |.  |.. .. ||||   .|..|||  |....||   .   |  ||  .||. .. ...|
faykvifpnhffmlrgnhecslinkiygfyeecqrrynkpsvyvsfegvfsvmpltalvgqril
subfamily_PPP5C_pd Subfamily PPP5C 2-63 5.2e-27 87.7 In-house 118-180 (322) alignment 
Range on Protein: 2-63
Range on HMM: 118-180/322.0
TFCVVHVNYL-IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.| ... | . .  |||| ..||..||||||||.||. |.|||||||||||||||||..||||
gfkllyPnhfflsrGnhesdnmnklyGfegevkakytekvadlftevfnwlPlahvinekvlv
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 2-62 2.6e-10 33.0 In-house 96-161 (302) alignment 
Range on Protein: 2-62
Range on HMM: 96-161/302.0
TFCVV-HVNYLIFLGNHELITMNQMYGFEGEVKKKY----NGKMADLFTEVFNWLPLAHVIDNKVL
.. |.   ||... ||||  ..|  |||..|.....      .. . | ||| ..||| .. .|.|
alkvlyptnyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekil
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 2-62 2.9e-10 32.8 In-house 97-162 (302) alignment 
Range on Protein: 2-62
Range on HMM: 97-162/302.0
TFCVV-HVNYLIFLGNHELITMNQMYGFEGEVKKKY----NGKMADLFTEVFNWLPLAHVIDNKVL
.. |.   ||... ||||  ..|  |||..|.....      .. . | ||| ..||| .. .|.|
alkvlyptnyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekil
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 5-62 2.7e-06 19.8 In-house 102-163 (307) alignment 
Range on Protein: 5-62
Range on HMM: 102-163/307.0
VVH-VNYLIFLGNHELITMNQMYGFEGEVK---KKYNGKMADLFTEVFNWLPLAHVIDNKVL
...  | ... ||||.  .|. |||  |.     |   ..  ||  .|| ||.. .|  |.|
icypenivllrgnheiarvnkkygfyeecvtsipkcgeeiwalfqrcfnnlpisaliatkil
PPP_5_Dcr2 6-63 6.7e-16 51.8 In-house 58-116 (199) alignment 
Range on Protein: 6-63
Range on HMM: 58-116/199.0
VHVNYLIFLGNHELITMNQMYGFEGEVKKKYNGK-MADLFTEVFNWLPLAHVIDNKVLV
.  .. .  ||||   .|..|||. ||..||.|| . . ...||.|||||..||.||||
ypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdvfdwlPlaalidekvlv
subfamily_PPP7C_pd Subfamily PPP7C 6-63 1.4e-14 46.6 In-house 121-182 (383) alignment 
Range on Protein: 6-63
Range on HMM: 121-182/383.0
VHVN-YLIFLGNHELITMNQMYGFEGEVKKKY---NGKMADLFTEVFNWLPLAHVIDNKVLV
|. .   .  ||||   .|  |||  ||..||   . |.  |. .|| ||||| .||.|.|.
vypkevylnrGnhedhilnlryGfikeveskykvhgkkilrlledvfawlplatlidekili
PPP_4 7-63 2.3e-16 53.4 In-house 59-115 (197) alignment 
Range on Protein: 7-63
Range on HMM: 59-115/197.0
HVNYLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVLV
  .. .  ||||   .|..|||. ||..|.. .. . ...||..||||..||.||||
pkevvllRGNHEskslnllygfkkevlekhgkeilkklqdvfdllplaalidekvlv
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 8-62 4.9e-14 45.1 In-house 110-165 (298) alignment 
Range on Protein: 8-62
Range on HMM: 110-165/298.0
VNYLIFLGNHELITMNQMYGFEGEVKKKY-NGKMADLFTEVFNWLPLAHVIDNKVL
 |.... ||||  ..|..|||  |.|..| . ..   | .|||.|||. .| ...|
nnffllrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggril
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 8-62 4.4e-13 42.2 In-house 109-164 (297) alignment 
Range on Protein: 8-62
Range on HMM: 109-164/297.0
VNYLIFLGNHELITMNQMYGFEGEVKKKYNG-KMADLFTEVFNWLPLAHVIDNKVL
 |.... ||||   .|..|||  |..|.|.  .|   | .|||||||. .| .|.|
gnlfllrgnhecefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkil
subfamily_PPZ_pd Subfamily PPZ 8-62 2.9e-10 33.1 In-house 111-165 (300) alignment 
Range on Protein: 8-62
Range on HMM: 111-165/300.0
VNYLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
 |.... ||||   . ..|||  |.|.. | |.   | . || |||| ..  |..
enffllrgnhecanvtrvygfydeckrrcnikiwktfvdtfntlplaaivagkif
Metallophos Calcineurin-like phosphoesterase 8-63 9.1e-09 28.9 Pfam-A 66-155 (200) alignment 
Range on Protein: 8-63
Range on HMM: 66-155/200.0
VNYLIFLGNHELITMNQMYGFEGEVK----------------------------------KKYNGKMADLFTEVFNWLPLAHVIDNKVLV
...   .||||   .|. |||  |.                                   ...... .. . |.|..|||.. .|.|.|.
ipvfllrGNHesdpgnsaygflleqlkdlrglangeeeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkill
PPP_1 9-63 3.4e-18 58.9 In-house 87-143 (264) alignment 
Range on Protein: 9-63
Range on HMM: 87-143/264.0
N-YLIFLGNHELITMNQMYGFEGEVK-KKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.   .  ||||  .....|||. ||. |||. .. ...|.||..|||| .||.|.|.
kelfllRGNHEsrqvtkvygFkkEvlkkkyskeiyktltdvFdvLplaalidekili
PP2Ac_SM00156 9-63 7.4e-18 57.5 In-house 88-142 (271) alignment 
Range on Protein: 9-63
Range on HMM: 88-142/271.0
NYLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.. .  ||||   .|..|||| ||| ||. .. . |.|.|..|||| ..|.|.|.
kvvLLRGnHEsssvnkiygfeeevkrkygkeiyekfeeafsllPlaalvdskilc
PPP_3 9-63 1.4e-17 56.6 In-house 89-144 (271) alignment 
Range on Protein: 9-63
Range on HMM: 89-144/271.0
NYLIFLGNHELITMNQMYGFEGEVK-KKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.  .  ||||  ..|..|||. ||. ||.. |. . ..|||..||||..||.||||
evhLlRGnhEsrqinkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlv
PPP_2 9-63 5e-17 55.2 In-house 59-114 (198) alignment 
Range on Protein: 9-63
Range on HMM: 59-114/198.0
NYLIFLGNHELITMNQMYGFEGEVK-KKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.  .  ||||  ..|..|||. ||. ||.. |. . ..|||..||||..||.||||
evhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfelLplaalidekvlv
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 9-62 7e-13 41.3 In-house 93-146 (280) alignment 
Range on Protein: 9-62
Range on HMM: 93-146/280.0
NYLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
|.||. |||| |..|. |||  |||..|. .. . | |... |||. ..  ..|
nflilrgnhevisinrkygfkdevkrryslalynefqelldslplvalvsgril
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 9-62 1.2e-10 34.1 In-house 111-165 (299) alignment 
Range on Protein: 9-62
Range on HMM: 111-165/299.0
NYLIFLGNHELITMNQMYGFEGEVKKKYNG-KMADLFTEVFNWLPLAHVIDNKVL
.. .. ||||  ..|..|||  |..|.|.  ..  .| . |...||. .| ...|
rffmlrgnhecpainrvygfyeecnkrykstrlwsifqdafaampltgligsril
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 9-62 1.9e-10 33.4 In-house 95-148 (281) alignment 
Range on Protein: 9-62
Range on HMM: 95-148/281.0
NYLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
. ... ||||. ..|..|||  | . ||  ..  || . || ||..  |...||
rivllrgnheiasvnkiygfyvecvtkyGeelwalfqrcfnrlpisaliakrvl
0049330 Metallo-dependent phosphatases 10-63 5.5e-15 48.6 In-house 118-171 (309) alignment 
Range on Protein: 10-63
Range on HMM: 118-171/309.0
YLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVLV
  . .|||||  .|..||| .|.. ||. .. . |......||||.||..|.|.
vfllrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilc
0053225 Metallo-dependent phosphatases 10-62 2e-13 43.7 In-house 110-163 (293) alignment 
Range on Protein: 10-62
Range on HMM: 110-163/293.0
YLIFLGNHELITMNQMYGFEGEVKKKY-NGKMADLFTEVFNWLPLAHVIDNKVL
  . .|||||  .|..||| .|.. || . .. | .......||||..|..|.|
vvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkil
subfamily_PPP3C_pd Subfamily PPP3C 10-62 1.1e-10 33.9 In-house 129-181 (452) alignment 
Range on Protein: 10-62
Range on HMM: 129-181/452.0
YLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
. .. ||||   . . . |. |.|.||. .. | ..| |. |||| ..... |
lfllrGnhecrhlteyftfkeeckikyseevydacmesfdslPlaallnqqfl
subfamily_PPPLV_pd Subfamily PPPLV 10-62 2.6e-08 26.5 In-house 89-144 (290) alignment 
Range on Protein: 10-62
Range on HMM: 89-144/290.0
YLIFLGNHELITMNQMYGFEGEVKKKYNGKMAD---LFTEVFNWLPLAHVIDNKVL
.|.. ||||| .. . . . || . |.  .. .    |..||..|||| |||.||.
vlllrgnhelesvqesieykgegsfkfgdsleevweafnnvfdalplaavidrkvf
subfamily_PPP1C_pd Subfamily PPP1C 11-62 3.2e-16 52.3 In-house 99-150 (282) alignment 
Range on Protein: 11-62
Range on HMM: 99-150/282.0
LIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
 .  ||||   .|..|||  |.|..|. |.   ||.|||.|||| ..|.|.|
fllrGnhesasinriyGfydeckrrysiklWktftdvfnclPlaalvdekil
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 12-62 3.1e-14 45.6 In-house 100-150 (287) alignment 
Range on Protein: 12-62
Range on HMM: 100-150/287.0
IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||.  .|..|||. |.|.|.....   | .||. |||   .....|
llrGnhevkkinklyGfkeelkrkrqerlykqfndvfselplcarvskril
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 12-62 3.6e-13 42.2 In-house 106-156 (290) alignment 
Range on Protein: 12-62
Range on HMM: 106-156/290.0
IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||   .|..|||  |. .| ....   . .||. |.|   ...|.|
llrgnhevrkvnrlygfkeelarkrgsrlwkqyqdvfaelslcarvgrkil
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 12-62 2.6e-12 39.5 In-house 136-186 (317) alignment 
Range on Protein: 12-62
Range on HMM: 136-186/317.0
IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||  ..|. |||  ||||.|. .. . |  .|| |||. |...|.|
llrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkil
subfamily_PPP2C_pd Subfamily PPP2C 12-62 9.2e-11 34.5 In-house 107-158 (290) alignment 
Range on Protein: 12-62
Range on HMM: 107-158/290.0
IFLGNHELITMNQMYGFEGEVKKKY-NGKMADLFTEVFNWLPLAHVIDNKVL
|. ||||   . |.||| .|. .|| | ..  .||..|..|||. ..|....
ilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqif
subfamily_PPG1_pd Subfamily PPG1 12-61 2.4e-10 33.1 In-house 104-155 (300) alignment 
Range on Protein: 12-61
Range on HMM: 104-155/300.0
IFLGNHELITMNQMYGFEGEVKKKY--NGKMADLFTEVFNWLPLAHVIDNKV
.. ||||   . |.||| .|. .||  | .. . .||.|..| || .||...
llrgnhesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideei
subfamily_PPP4C_pd Subfamily PPP4C 12-62 2.9e-10 32.8 In-house 106-157 (288) alignment 
Range on Protein: 12-62
Range on HMM: 106-157/288.0
IFLGNHELITMNQMYGFEGEVKKKYN-GKMADLFTEVFNWLPLAHVIDNKVL
.  ||||   . |.|||  |. .||   ..  . ||||..|.|| .||.|..
lirgnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkif
subfamily_PPP6C_pd Subfamily PPP6C 12-62 3.1e-10 32.6 In-house 105-156 (290) alignment 
Range on Protein: 12-62
Range on HMM: 105-156/290.0
IFLGNHELITMNQMYGFEGEVKKKY-NGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||   . |.|||  | ..|| |..    .|.||. |..| .||..||
llrgnhesrqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvl
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 12-62 1.4e-09 30.5 In-house 155-205 (339) alignment 
Range on Protein: 12-62
Range on HMM: 155-205/339.0
IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||  ..|  |||  ||. .|. .. . | ..|| .|.. ||.| ..
llrgnhesrsvntsygfyrevnyrydaqlyecfqnmfnvfpfcavinntim
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 12-62 1e-07 24.7 In-house 96-146 (280) alignment 
Range on Protein: 12-62
Range on HMM: 96-146/280.0
IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||  ..|..|||  |.. ||   .   |  .|| .|.. .| ..||
llrgnhetpsvnkiygfyvecqykygvglwwdfqscfnrmpmsgliskrvl
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 12-62 1.1e-07 24.8 In-house 70-125 (263) alignment 
Range on Protein: 12-62
Range on HMM: 70-125/263.0
IFLGNHELITMNQMYGFEGEVKKKYNGK-----MADLFTEVFNWLPLAHVIDNKVL
.. ||||| ..|. |||  |.||... .     . . | .||...||. .. ...|
llrgnhelkainknygfhaelkkrfqreevyesvynhfnqvfsymplcaivskril
0045823 Metallo-dependent phosphatases 14-63 3.2e-15 48.9 In-house 135-184 (473) alignment 
Range on Protein: 14-63
Range on HMM: 135-184/473.0
LGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.|||||  .|..||| .|. .||. .. . | |....||||.||..|.|.
rGNHElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilf