Gene PHP in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PHP
Superfamily PHP
Family PHP
Subfamily PHP
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP198_AA protein Get Run
AqueP198_AA_0-117 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Ocnus Janus/Ocnus family (Ocnus) 1-106 9.6e-40 124.7 Pfam-A 1-107 (108) alignment 
Range on Protein: 1-106
Range on HMM: 1-107/108.0
MEKVPEVDIESDGVFKYILVELTDKKSGKVKTIVRGYEWAEYHADILDRIAPRVSELGLEYKCVGGGRIRHQ-KSKSIHVYGYSVDFGQADHKMTIDILK
..|||||||...|.|||.|.....|.. . |..|||...||||||| ....  ...|||| .|.|||||.|. ..|.|.|||||  ||.|||... .|||
LakvpevdideeGkfkYvlikvkikekdeskevvrglkkaeyHadiyekvkkeleklgleteclGGGriehdeekkkikvyGyskgfGkadheiakeilk

RNFTDYE
....|||
kkykdye
Ocnus Janus/Ocnus family (Ocnus) 1-106 9.6e-40 124.7 In-house 1-107 (108) alignment 
Range on Protein: 1-106
Range on HMM: 1-107/108.0
MEKVPEVDIESDGVFKYILVELTDKKSGKVKTIVRGYEWAEYHADILDRIAPRVSELGLEYKCVGGGRIRHQ-KSKSIHVYGYSVDFGQADHKMTIDILK
..|||||||...|.|||.|.....|.. . |..|||...||||||| ....  ...|||| .|.|||||.|. ..|.|.|||||  ||.|||... .|||
LakvpevdideeGkfkYvlikvkikekdeskevvrglkkaeyHadiyekvkkeleklgleteclGGGriehdeekkkikvyGyskgfGkadheiakeilk

RNFTDYE
....|||
kkykdye
subfamily_PHP_pd Subfamily PHP 2-114 8.7e-48 151.0 In-house 2-113 (114) alignment 
Range on Protein: 2-114
Range on HMM: 2-113/114.0
EKVPEVDIESDGVFKYILVEL-TDKKSGKVKTIVRGYEWAEYHADILDRIAPRVSELGLEYKCVGGGRIRHQKS-KSIHVYGYSVDFGQADHKMTIDILK
..||||||.|.|.|||.|.|| ||....| |||||||..|||||||..........|||..||.|||||.|.|. |.|.|||||..||.|||... .|||
aavpevdidskGkfkYvlielttdsegkksktivrgyskaeyhadiyeevkeeleklglkakclGGGriehdkekkkikvyGyskgfGkadheiakeilk

RNFTDYeseNITFSN
....||   .||.||
tkypdy...kitisn
PHP 2-117 3.7e-44 139.6 In-house 4-121 (121) alignment 
Range on Protein: 2-117
Range on HMM: 4-121/121.0
EKVPEVDIESDGVFKYILVELTDKKSG----KVKTIVRGYEWAEYHADILDRIAPRVSELGLEYKCVGGGRIRHQK-SKSIHVYGYSVDFGQADHKMTID
.|||.|||...|||||.|...|.|..     . |..||||..|||||||.||..  ... ||. .|.|||||.|.. .|.|.|||||| .|.|||..| .
akvpdvdidpeGvfkyvlirvtskerkdgaaaskevvrGyaraeyhadiydrvsselekqgldaeclGGGriehdseekkikvyGysvgyGkadhavtke

ILKRNFTDYeseNITFSNSGY
.|| .. ||   .||.|. ||
klktkyPdy...eitlsdeGy
0053050 PHP14-like 2-106 7.3e-39 121.6 In-house 3-113 (118) alignment 
Range on Protein: 2-106
Range on HMM: 3-113/118.0
EKVPEVDIESDGVFKYILVELT-----DKKSGKVKTIVRGYEWAEYHADILDRIAPRVSELGLEYKCVGGGRIRHQ-KSKSIHVYGYSVDFGQADHKMTI
 |||||||...|||||.|...|     |... . |.||||. .|||||||.... ... .|||...|.|||||.|. ..|.|.|||||. ||.|||....
akvpevdideeGvfkYvlikvtlkgltdsggkesklivrglkkaeyHadiyeevskeleklgldleclGGGriehdsekkkikvyGyslgfGkadheial

DILKRNFTDYE
.|||  ..|||
eilktkypdye