Gene TAB1-3 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily TAB1
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP214_AA protein Get Run
AqueP214_AA_34-356 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PP2Cc_SM00332 35-353 2.8e-31 101.9 In-house 16-273 (274) alignment 
Range on Protein: 35-353
Range on HMM: 16-273/274.0
GQSSQTRNNEDRYYSGCQ----GNIQLCMVLDGHQGESAAEFTVLSLAGKILSESR-IE-----DPKLLLERVFRETEDSFFVGMDDPI--Grrlalkae
 .  . ...||.. .  .     .  .. | ||| |...|.|.   |   . .|    .     |.. .|...|..|.. .    .              
smqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen........

lnqrpaggsferhrdlqqdelrrldsqIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGLDIGQLlqlR
                              |.|.|..|.. ...|| ||.||||||||...|     | ||| ||......| .|.|| |  . .    |
...........................alsGstavvallk.kedlyvanvGDSravlcrngk.....avqlsvdhkpedederkRikkaggvvekg...r

RLGPFQITRSIGDYLIKGGYtevdvlrsA----------------SqgpgiatpfvngpwdisnLQNKTFLILMSDGLYEaygscinTRNPPELHSSLAR
  |  ...|..||.  |                                                ... ||||.||||..         .. |... . .
vngglavsrafGdhflkknk........klkepyitaepdvkvvtl..................tsedeflilaSDGlwd.......vlsnqevvdivrk

LVMDEmrlhnrldrvgqaVVNRVKEQYREICRRDRKD-GKLDDMTLII
| . .             . |...|   ....  ... |. |..| ..
llakg.............ktndpqeaaelldeeairrggseDniTvvv
subfamily_TAB1_pd Subfamily TAB1 37-357 4.3e-64 209.4 In-house 8-332 (333) alignment 
Range on Protein: 37-357
Range on HMM: 8-332/333.0
SSQTRNNEDRYYSGCQGNIQ-LCMVLDGHQGESAAEFTVLSLAGKILSES-----RIEDPKLLLERVFRETEDSFFVGMDDPIGRRLALKAELNQRPAGG
|..  ..||. .  .  | . |  | ||..|..||.|    |  ..| |        ...|  |.| | |.| .|.  .|| .  .  |. .| .  .  
skedhevedkvflfktendpilyavFdGydGnkaakfveqrLvaellleqltdelaeaevkevlkrafeeverkflesiddalaekddlqsqlPegvssy

SFERHRDLQQDELRRLDSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngRIIASQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQIT
  |.. . . . |. |...| |||| |. ||  ||.|| ||.|||||.|... .       ||| ||.. |..|  |||.||||| |. . .|||  . |
eleeqypekierlqeleeeisgGttAvvalif.nnkLyVaNvGdsrAllvkrke..sekvkqLsvdHttdNedEllRlkdLGldieqikrnkrlgskent

RSIGDYLIKGGYTEVDVLRSASQGPGIATPFVNGPWDISNLQnkTFLILMSDGLYEAYGSCINTRNpPELHSsLARLVMDEMRLHNRLDRVGQAVVNRVK
|||||| .|.||..||.| ||.. |.||.| ..|...| ...   ||.|||||.|..     .. .  .... ..  |. |.  .  |. | ||||..||
RsiGdykvkkgykdvdilssakgePviaePdiqgaypiddit..yflvlmSdGvyktLeevtgpet.snven.illevitelekqatlqdvAqavvdkvk

EQYREICRR-----DRKDGKLDDMTLIIQNFT
 . ..          .   | |||||.. .| 
rkHkdaylssaseravicrkrddmtllvlkfe
PP2C_2 Protein phosphatase 2C 39-307 8.7e-07 21.4 Pfam-A 8-194 (212) alignment 
Range on Protein: 39-307
Range on HMM: 8-194/212.0
QTRNNEDRYYSGCQGNIQLCMVLDGHQGESAAEF----TVLsLAGKILSESR----IEDPKLLLERVFRETEDSFFvgmddpigrrlalkaelnqrpagg
.  ...|...   . . .|..| ||.   . ..      |   ||. |...      .. . ||... .| . |                          
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlave.aagealeklleeeseqeeeallrqieneilasvk........................

sferhrDLQQDELRRLdSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNvfnPEeqdrL---KK------Lgldigqllql
      . |. | ..  .  . .||..| .|| ..... ..|||...|. ..|.. ... .. | ..     |    .   ..      |          
......lkqeaeaqqe.elkdyatTlllavit.pgeivffqiGDgaivvrdrdgevqllgepdsgeya...ne....ttfltsedaeeel..........

rrlgpfqitrsigdylikggytevdvlrsasqgpgiatpfvngpwDISN--LQNKTFLILMSDGLYEAYgscintRNPPELHSSLARL
                                             .|..  |.  . |.||.||. ...      |....... ||.|
.............................................rirrlklepgdalllmTDGvsdsl......rkeepfrellael
PP2C_2 Protein phosphatase 2C 39-307 8.7e-07 21.4 In-house 8-194 (212) alignment 
Range on Protein: 39-307
Range on HMM: 8-194/212.0
QTRNNEDRYYSGCQGNIQLCMVLDGHQGESAAEF----TVLsLAGKILSESR----IEDPKLLLERVFRETEDSFFvgmddpigrrlalkaelnqrpagg
.  ...|...   . . .|..| ||.   . ..      |   ||. |...      .. . ||... .| . |                          
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlave.aagealeklleeeseqeeeallrqieneilasvk........................

sferhrDLQQDELRRLdSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNvfnPEeqdrL---KK------Lgldigqllql
      . |. | ..  .  . .||..| .|| ..... ..|||...|. ..|.. ... .. | ..     |    .   ..      |          
......lkqeaeaqqe.elkdyatTlllavit.pgeivffqiGDgaivvrdrdgevqllgepdsgeya...ne....ttfltsedaeeel..........

rrlgpfqitrsigdylikggytevdvlrsasqgpgiatpfvngpwDISN--LQNKTFLILMSDGLYEAYgscintRNPPELHSSLARL
                                             .|..  |.  . |.||.||. ...      |....... ||.|
.............................................rirrlklepgdalllmTDGvsdsl......rkeepfrellael
0034914 PP2C-like 40-356 6.3e-31 100.4 In-house 32-290 (295) alignment 
Range on Protein: 40-356
Range on HMM: 32-290/295.0
TRNNEDRYYSGC-----QGNIQLCMVLDGHQGESAAEFTVLSLAGKILSE---------SRIEDPKLLLERVFRETEDSFFVGMDDPigrrlalkaelnq
 ..|||...  .     .... |. | ||| | .|||.    |   .|..         . .||..  |...| ...  ..    .              
rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallr.............

rpaggsferhrdlqqdelrrlDSQIEGGTTVVLSLItTNNQLYTANIGDSRAVLCeedKNGriIASQLSDDHNVFNPEEQDRLKKLGLDIGQllqLRRLG
                      . . .|||.|. || ..|.||.||.|||||||.   .||   . ||. ||.. |..|. |....|  .      |..|
.....................pelagsGtTavvali.rgnklyvanvGDSravll...rng..elvqltvdhkpvnelererilsaggavsh...grvng

PFQITRSIGDYLIKGGYTEvdvlrSASQGPGIATPFVNgpWDISNLQNKTFLILMSDGLYEAYGscintrnppelHSSLARLVMDEMRLHNRLDRVGQAV
 ...||..||.  |  ..       ... . .|.| |   .   .|..  ||.|.||||..              .. ....|.. .. .. |. . ...
vlavtRalGdfdlklllsl.....llleplvsaePdvt..vleltledddfllLasDGlwdvls...........neeivdivrsllakgldleeaaeeL

VNRVKEqyreicrrdrkDGKLDDMTLIIQNF
|... .            |. |..| ..  .
vdlAla...........rgsrDNiTvvvvrl
0049733 PP2C-like 40-353 6.4e-26 84.3 In-house 15-230 (235) alignment 
Range on Protein: 40-353
Range on HMM: 15-230/235.0
TRNNEDRYYSgcqgNIQLCMVLDGHQGESAAEFT---VLSLAGKILSESRIEDPKLLLERVFRETEDSFFVGmddpigrrlalkaelnqrpaggsferhr
 ..|||...     .. |. | ||| |  |.|.    ....  ..| |  ..|.. .|...|..... ..                              
rkvneDavlv....glllfavaDGhgghaagevasellvetllelllelllldleealrkaflaaneallel............................

dlqqdeLRRLDSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGLDIgqllqlRRLGPFQITRSIGDY
       ..  .   .|||.|. |.. ...||.||.|||||.|. ..|     . ||. ||...|..|. |....|  .      | .|  ..||..||.
......alaspelagmgtTavvalld.ggklyvanvGDsrayllrdgk.....lvqltedhspvnelerqriitaggav......rvpgrlaltralGdl

LIKggytevdvlrsasqgpgiatpfvnGPWDISNLQNKTFLILMSDGLYEAygscintR------------NPPELHSSLARLVMDemrlhnrldrvgqa
|.|                          . . .|..  ||.|.||||..                     .. |. . |..|...              
llk........................pdvtvlelepgdflllasDGlwdv.......lsdeeivdllrsldleeaaerlvelala..............

vvnrvkeqyreicrrdrkDGKLDDMTLII
                   |. |..|...
..................rggrDNiTvvv
subfamily_PPM1A_pd Subfamily PPM1A 40-288 5.7e-24 77.9 In-house 23-234 (282) alignment 
Range on Protein: 40-288
Range on HMM: 23-234/282.0
TRNNEDRYYSGCQG----NIQLCMVLDGHQGESAAEFTVLSLAGKILSESRIEDpklllervfretedsffvgmddpigrrlA-----LKAELNQRPAGG
 ...||..   ..     . ..  |.||| |...|...   | ..||.|.....                            |      | |...    |
rvemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenileeeelke............................aaleasekdevkealrqg

SFERHR--------------DlqqdelrrldsqiegGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGldiG
 .. .                               |.|.|  |.. ...|..||.||||||||.. |     |  |..||   .|.|..|... |   |
fLaldeairelstdlktadks...............GsTavtvlvs.ekhliianlGDsRavlcrngk.....aaflteDHkpsrpkEkkRieqAG...G

QLLQLRRLGPFQITRSIGDYLIKGGYTEVDVLRSASqgpgiATPFVNgpwDISNLQNKTFLILMSDGLYEAY
...  |  |   ..|..||| .|   .     .  |     | | |.    |.  ....||.| .||...  
svvvsRvnGaLAvsRalGDyeykeeeekkaeeqlvs.....aepevt...sierseeddflvlacDGiwDvl
PP2C_SIG_SM00331 47-353 3e-09 29.8 In-house 20-214 (217) alignment 
Range on Protein: 47-353
Range on HMM: 20-214/217.0
YYSGCQGNI--QLCMVLDGHQGESAAEFTVLSLAGKILSESRI-EDPKLLLERVFRETEDSffvgmddpigrrlalkaelnqrpaggsferhrdlqqdel
||   . |   .|..| ||. .  ||.    .| ...  ...  |... .|.|. |  ..                                        
yydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellsegeelsqalkrlnraiyee.......................................

rrlDSQIEGGTTVVLSLI-TTNNQLYTANIGDSRAVLCEEDKNGRIIASqlsddhnvfnpeeqdrlkklgldigqllqlrrlgpfqitrsigdylikggy
   .   ....|..| |. .....|. ||.|||| .|  ..|   |. .                                                   
...keekgmfaTlllalydfssgklsyanaGdsrpyllrdgklveilkd...................................................

tevdvlrsasQ-----------GpgiatpfvngpWDISNLQ--NKTFLILMSDGLYEAYGSCIntRNPPELHSSLARLVmdemrlHNRLDRVGQavvnrv
          .                        ||..|.   . .|.|..||| ||  .     .  .|   |. ||      .. .....|      
..........vegaplGlepevs...........vdirelelekgdllllytDGltearsekg..faeerleeiledlv......dseaqelaq......

kEQ------------YreicrrdrkdgkLDDMTLII
 .             .             ||.|...
.kiveellelakgsng............eDdiTvvv
subfamily_PPM1G2_pd Subfamily PPM1G2 54-289 8.6e-17 54.0 In-house 51-235 (287) alignment 
Range on Protein: 54-289
Range on HMM: 51-235/287.0
NIQLCMVLDGHQGESAAEFTVLSLAGKILSesriedpklllervfretedsffvgmddpigRRLALKAELNQRPAGGSFERHRDLQQDelRRLDSQIEGG
...|  |.||| |...|...   |  || .                               ..   . .|.|    .  |  ..|..|  ..|. .  | 
slalfavfDGhGGakvakyagkklikkiak...............................kksfkegaleqilkdafletDeellkd..eklkdesaGs

TTVVlSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGldiGQLLQLRRLGPFQITRSIGDYLIKGGYTevdvlRSASQ
|.||  ||. ...|| ||.|||||||... .     ...|| ||   . .|. |... |   |     |  |   . |..||.  | . .      .. .
tavv.vlik.eeklyvanaGDsravlsskgn.....vkalsfDhkPqeesekkriiaag...GfvelnrvngnLalsralgDfefkknvk.....kkpee

GPGIATPFVNGpWDISnlQNKTFLILMSDGLYEAYG
    |.| |    ...  ... ||.|  ||... . 
qivtavPDvlv.kkld..eddeflvLaCDGiWDvlt
subfamily_PPM1L_pd Subfamily PPM1L 54-289 9.1e-17 54.2 In-house 34-224 (269) alignment 
Range on Protein: 54-289
Range on HMM: 34-224/269.0
NIQLCMVLDGHQGESAAEFTVLSLAGKILSesRIEDPklllervfretedsffvgmddpigrrlaLKAELNQRPAG-GSFERHRDLQQD--ELRRLDSQI
..... | ||| || ||||.   |. .|..  .. .                              ..  |. |   . .  .. |  |   | .. .. 
gesffavfdGhGGefaaefakdvlvkaikn..kliel............................dadkentepinfsklltdeilsvdekllekakrae

-EGGTTVVLSLITtNNQLYTANIGDSRAVLCeeDKNGRIIasQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQITRSIGDYLIKggytEVDVLr
 . |||....|.. ...|  ||.|||| ||.  ||.|. |   || ||   ...|. |.|| |  |      |  | . ..|..||| .|    . ... 
diaGttalialvq.esdlivanvGdsrGvly..dkrGkai..plsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplk....dknlv.

sasqgpgIATPFVNGpWDISNLQnKTFLILMSDGLYEAYG
       ||.| .   .|. ...   |||| ||||.... 
.......iadpdilt.fdlddhk.peflilasdGlwdtfs
subfamily_PPM1D_pd Subfamily PPM1D 56-215 9.3e-14 44.2 In-house 36-171 (309) alignment 
Range on Protein: 56-215
Range on HMM: 36-171/309.0
QLCMVLDGHQGESAAEFTVLSLAGKILSESRIedpkL------LlervfretedsffvgmddpigrrlalKAELNQRPAGGSFERHRDLQQDELRRLDSQ
    | ||| |. ||.|.   | ..|  .. .    |      .                           . ...       . .. |..   ..    
afvavfDGHGGkeAakfarehlwsvikkqkkf....lssepedv..........................leAireaflatheamkkkleeWpktksgll

IEGGTTVVLsLITTNNQLYTANIGDSRAVLCEEDK-NGRIIASQLSDDHNVFNPEEQDRLKKLGLDI
   |||. . .| ....||.|..|||..||  ... . ...|..| .||   .|||. |...|| ..
staGttasv.viirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGev
subfamily_PPM1H_pd Subfamily PPM1H 59-219 3.7e-10 32.1 In-house 66-221 (404) alignment 
Range on Protein: 59-219
Range on HMM: 66-221/404.0
MVLDGHQGESAAEFTVLSLAGKIlsESRIEDPKLLLERVFRETEDSFFVGM-DDPIGRRLAL-KAEL-NQRPAGGSFERHRDLQQDE--LRRLDSQIEGG
 . ||| |..||  ..  |  ..  ....|| . || .  .|.|. .     ..|  ..    . |. ...   |..|       .     | . .|.||
glfDGhaGsgaalvaskllhkhl..kekledvlellleksaeeeenteesskespssvseiyeekeiskeeLviGalesaflemDeqiarereayrikGG

TTVVLSLItTNNQLYTANIGDSRAVLCEEDKNgriiaSQLSDDHNvfnPE-EQDRLKKLGLDIGQLL
 |.. .|.  ...|| || |||||.|...|.       .|| |.    || |. ||..|.    .||
Ctalvalv.llgklYvanaGDsRailvrkdei.....iplsadft...PeteRqRlqelaflkPeLl
subfamily_KAPP-like_pd Subfamily KAPP-like 129-287 1.4e-12 40.2 In-house 73-218 (266) alignment 
Range on Protein: 129-287
Range on HMM: 73-218/266.0
GGSFERHRDLQQDELRRLDSQI-----EGGTtVVLSLITT-NNQLY--TANIGDSRAVLCEEDKngRIiasQLSDDHNVFNPEEQDRLKKLGLDIGQllQ
| .    ..| .. .. .|...     || |   |.|. .  .| |  .||.||| | |.  ..   .   .|| ||.  .|||. |.|. |. . .  .
GdniydqskllenafkevdaklkdfeyeGat.atlalvwsdGqqrylqvanvGdssaflsrGne..sl...elskdhkakdpeekqrikddGitlsd..n

LRRLGPFQITRSIGDYLIKggytE--VDVlrsasqgpgIATPFVNGPWDISNLqnKTFLILMSDGLYEA
  |.    ..|..||..||    |  . .         |..|.|  .. ..    . |||. ||||.. 
qtrinGlavsralGdhfik....elniGl.........isepyvsnrilltpf..dkflivasdGlwdv
subfamily_PPM1K_pd Subfamily PPM1K 134-239 4.6e-13 41.9 In-house 84-182 (263) alignment 
Range on Protein: 134-239
Range on HMM: 84-182/263.0
RHRDLQQDELrrldSQIEGGTTVVLSLITTNNQLYTANIGDSRAVLCeedKNGRiiASQLSDDHNVFNPEEQDRLKKLGLDI--GQLLQLRRLGPFQITR
|.  ..  |     .. . |||  .||.   ..|  |..|||||.||   .||.  |..|..||.    ||..|.|. |  .    | ...  | . .||
rylefsvaea....ellssGttatvsllrdGtelvlaslGdsrailc...rnGk..akkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtr

SIGDYLIK
|.||  .|
slGdldlk
PPM_PTC7 135-287 2.3e-27 89.1 In-house 80-220 (259) alignment 
Range on Protein: 135-287
Range on HMM: 80-220/259.0
HRDLQQDELRRLD----SQIEGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGriiaSQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQIT
.. |..||  ...      . .|.| |. ||| .. ||.||.||||||||  ...      ||. ||.. |..| .|....|  . .  . |  | .. .
flaldtdeelksseantepstsGstAvvalitgsk.lyvAnvGDSravLcrsgnav....kqltedHkpsnedEreRiegaggsvsnvgngrvngvlavs

RSIGDYLIKGGYTevdvlrsaSQGPGIATPFVNgpwDISNLQNKTFLILMSDGLYEA
|..||.  | ..|        .. . .|.| ..    . .  .  ||||.||||.. 
RafGdfelkpket........eeqlvsaePdis...stkideedefliLasdGlwdv
PP2C Protein phosphatase 2C 140-288 2.5e-27 89.1 Pfam-A 84-216 (255) alignment 
Range on Protein: 140-288
Range on HMM: 84-216/255.0
QDELRRL--D--SQIEGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGriiaSQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGD
.||  ..  .  ...  |.| |..||. .. ||.||.||||||||  |..      .|. || . ...| .|....|  . .  . |  | .. .|..||
tdeelksskantepsksGstavvalirgkk.lyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn..ngrvngsLavsRalGd

YLIKGGYtevdvlrsasQGPGIATPFVNgpwDISNLQNKTFLILMSDGLYEAY
. .| ..          . . .| | |.    ..  ..  ||||.||||.. .
felkpke..........eqlvsaePdvt...svklteedefliLasdGlwdvl
PP2C Protein phosphatase 2C 140-288 2.5e-27 89.1 In-house 84-216 (255) alignment 
Range on Protein: 140-288
Range on HMM: 84-216/255.0
QDELRRL--D--SQIEGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGriiaSQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGD
.||  ..  .  ...  |.| |..||. .. ||.||.||||||||  |..      .|. || . ...| .|....|  . .  . |  | .. .|..||
tdeelksskantepsksGstavvalirgkk.lyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn..ngrvngsLavsRalGd

YLIKGGYtevdvlrsasQGPGIATPFVNgpwDISNLQNKTFLILMSDGLYEAY
. .| ..          . . .| | |.    ..  ..  ||||.||||.. .
felkpke..........eqlvsaePdvt...svklteedefliLasdGlwdvl
PPM_PTC7_SpoIIE 141-290 6.8e-14 45.2 In-house 87-172 (230) alignment 
Range on Protein: 141-290
Range on HMM: 87-172/230.0
DelrrldsQIEGGTTVVLSLITTNN-QLYTANIGDSRAVLCEEDKNgriiasqlsddhnvfnpeEQDRLkKLGLDIGqL--L-QlRRLGPFQITRSIGDY
.        ...|.|.|. ||. .. .||.|| |||...|.  |.                   |  |. ..|  .  |  | . |  | .......||.
e.......psssgaTavvalidpstgklyvanaGdsppllvrddgg..................ereri.vagglps.lGilpg.rvfgvlavslapGdl

LIKGgytevdvlrsasqgpgiatpfvngpwdisnlqnktflilmSDGLYEAYGS
|..                                         .||. ||   
llly........................................tDGvveaepd
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 146-215 5.2e-09 29.0 In-house 79-148 (292) alignment 
Range on Protein: 146-215
Range on HMM: 79-148/292.0
LDSQIEGGTTVVLSLITTNNQLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNVFNPEEQDRLKKLGLDI
.| . ...|.|| . .  . .|. ||.|||||.|       .     || ||   .|.|. |... |  .
idaresattavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraGGrv
subfamily_PPM1E_pd Subfamily PPM1E 148-239 6.1e-12 38.3 In-house 98-183 (265) alignment 
Range on Protein: 148-239
Range on HMM: 98-183/265.0
SQIEGGTTVVLSLITTnNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQITRSIGDYLIK
 ....|.| |  ||.. .||| | .|||.|.|... .     | || . |.  ...|..|....|  . .. ..|  |  ...|.|||.  |
eklksGstavvvliek.dqlyvaWlGDsqallvrkge.....avqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 150-239 4.4e-13 42.1 In-house 93-178 (255) alignment 
Range on Protein: 150-239
Range on HMM: 93-178/255.0
IEGGTTVVLSLItTNNQLYTANIGDSRAVLCEEDKngriIASQLSDDHNVFNPEEQDRLKKLGLDIGQL-LQLRRLGPFQITRSIGDYLIK
.  ||| .  || .... | ||.||||.|||. |     .| .|| ||.  ...|. |...||  . .     |  | . ..|..||  ..
kfiGttaasvli.iedkvyianvGdsrvvlcqkdg....takrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsfle
subfamily_PDP_pd Subfamily PDP 151-287 1.5e-16 53.5 In-house 151-298 (398) alignment 
Range on Protein: 151-287
Range on HMM: 151-298/398.0
EGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNVFNPEEQDRLKKLGLDIGQ---LLQLRRLGPFQITRSIGDYLIKGGY-TEVD
  |.. .|.||  .. |. ||.||.||||. ....|   | .|| |... |.||  |.||   .  .   . . | ||  | .|  ||.  |    ..  
lsGacallaliegte.lhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwseelqkk

VLRSA---SQGP-GI-ATPFVNGPWDISNLQ---NKTFLILMSDGLYEA
||..|    . |    . |..    .. . .   |. ||.| .|||.. 
vlekaylkvlepkdyktPPYltaePevtshklrendkFLvlatDGLwdl
subfamily_PPM1G_pd Subfamily PPM1G 151-241 6.6e-14 44.7 In-house 295-377 (473) alignment 
Range on Protein: 151-241
Range on HMM: 295-377/473.0
EGGTTVVLSLITTnNQLYTANIGDSRAVLCEEdkngrIIASQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGDYLIKGG
. ||| |  |. . ..|. ||.||||.||...       | .|| ||   ...|..|..| |  . .  ..|  |   . | .||.  |  
dsGttAvvaLlke.kklivAnaGDsRcvlsrn.....GkAldlslDHkPeDevEleRiekAGGkvde..dgRvnGGLnlsRAlGDhaYkkn
subfamily_ILKAP_pd Subfamily ILKAP 152-288 2e-16 53.0 In-house 113-230 (293) alignment 
Range on Protein: 152-288
Range on HMM: 113-230/293.0
GGTTVVLSLItTNNQLYTANIGDSRAVLCEEDKNGR-IIASQLSDDHNVFNPEEQDRLKKLGldiGQLLQLRRLGPFQITRSIGDylikGGYTEVDVlrs
 |.|... |.  .| ||.||.|||.|||.  ...|. |.. .|. ||.  . ||. |..| |   |.. . | || ....|||||    | . .. |   
dGstatvvlv.ldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaG...gvvrdgrvlGvlevsrsiGd....grfkrlGv...

asqgpgIATPFVNgpwDISNLQNKTFLILMSDGLYEAY
      |.||.|.    .   .|  |..|  |||....
......istPdvk...kceLtendlfvvlaCdGLwkvf
subfamily_PP2D1_pd Subfamily PP2D1 165-217 1.3e-06 20.5 In-house 188-235 (492) alignment 
Range on Protein: 165-217
Range on HMM: 188-235/492.0
NQLYTANIGDSRAVLCEEdknGRiiASQLSDDHNVFNPEEQDRLKKLGLDIGQ
  || ||.|. .|||| |   |.  | .|  .|.  |..| .|..| |  . .
gvlyianaGnvqAvLcre...Gk..aiiLtreHtprnkkERtRvekagsvvvk
subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 166-287 2.5e-10 32.7 In-house 127-228 (276) alignment 
Range on Protein: 166-287
Range on HMM: 127-228/276.0
QLYTANIGDSRAVLCEEDKngRIiasQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGDYLIKggytE--VDVlrsasqgpgIATPFVN
 | .||.||| | |.  ..   .   .|| ||.  .|||..|.|. |. . .  .  |.    ..|..||..||    |  . .         |..|.| 
ylqvanvGdssaflsrGne..sl...elskdhkatdpeekqrikddGitlsd..nqtrinGlavsralGdhfik....elniGl.........isepyvs

GPWDISNLqnKTFLILMSDGLYEA
 .. ..    . |||. ||||.. 
nrilltpf..dkflivasdGlwdv