Gene TAB1-1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily TAB1
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP215_AA protein Get Run
AqueP215_AA_167-513 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0034914 PP2C-like 168-513 5.3e-39 126.9 In-house 9-290 (295) alignment
Range on Protein: 168-513
Range on HMM: 9-290/295.0
YSYNSVINCRYSITETSELSADPDHYNEDRVFFAK-----TDDVIVMAVFDGHDGNKASGLVEQYLFSKFINPDVLVglrFETKATLYALIDDVERVFFQ
... ...   ....  .       ..|||.|..       ..|.....||||| | .|. .. ..|.. ...    .   . .  . .  | .. |  |.
lellllsslllllrvgvasdqGrrksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekl...lllltlsledieealrkafl

KINDYIEEKNDIQstlpkglnsyqasllypdkinrlqeiEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVyRKHfeKFRQLSVDHCVDNEDELERLKD
... .. |..  .                             . .|||||.|....| |||||||||||. . |..  ...||.||| ..||.| ||...
aadeellelallr..........................pelagsGtTavvalirgnklyvanvGDSravll.rng..elvqltvdhkpvnelererils

LGLDIEQikrNGRLGSHENTRSIGDYNIKKGYKDvdilsSATGPPGIATPSISgPYPI--NDIEYILLMSDGVYKTLEcltdppTSDVYPRLLQLIQkae
.|  .     . ..|.   ||..||.. |. ...      ...|. .|.| ..  ...  .| ...||.|||....|.       ....  . .|..   
aggavsh...grvngvlavtRalGdfdlklllsl.....llleplvsaePdvt.vleltledddfllLasDGlwdvls......neeivdivrslla...

KSANLQDIAREVLQD--IealhkeayydsamtdprstvavnCRKRDDMTLMVLHF
|. .|...|.|...                           . .||..| .|...
kgldleeaaeeLvdlAla.......................rgsrDNiTvvvvrl

subfamily_TAB1_pd Subfamily TAB1 172-514 1.8e-158 519.6 In-house 1-332 (333) alignment
Range on Protein: 172-514
Range on HMM: 1-332/333.0
SVINCRYSitetselsaDPDHYNEDRVFFAKTDDVI-VMAVFDGHDGNKASGLVEQYLFSKFINPDVLVGL-RFETKATLYALIDDVERVFFQKINDYIE
||.|.|||         ..||..||.||..||.. . ..|||||.|||||...|||.|..........  | ..|.|..|......||| |...|.|...
svsnrrys.........kedhevedkvflfktendpilyavFdGydGnkaakfveqrLvaellleqltdelaeaevkevlkrafeeverkflesiddala

EKNDIQSTLPKGLNSYQASLLYPDKINRLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEKFRQLSVDHCVDNEDELERLKDLGLDIEQ
||.|.||.||.|..||... .||.||.||||.|.|..||||||.|..|||.|||||||||||..|.||..||..||||||..||||||.|||||||||||
ekddlqsqlPegvssyeleeqypekierlqeleeeisgGttAvvalifnnkLyVaNvGdsrAllvkrkesekvkqLsvdHttdNedEllRlkdLGldieq

IKRNGRLGSHENTRSIGDYNIKKGYKDVDILSSATGPPGIATPSISGPYPINDIEY-ILLMSDGVYKTLECLTDPPTSDVYPRLLQLIQKAEKSANLQDI
||||.||||.|||||||||..|||||||||||||.|.|.||.|.|.|.|||.||.| ..|||||||||||..|.|.||.|...||..|...||.|.|||.
ikrnkrlgskentRsiGdykvkkgykdvdilssakgePviaePdiqgaypiddityflvlmSdGvyktLeevtgpetsnvenillevitelekqatlqdv

AREVLQDIEALHKEAYYDSAmtdprSTVAVNCRKRDDMTLMVLHFS
|..|...... ||.||..||     |..||.|||||||||.||.|.
AqavvdkvkrkHkdaylssa.....seravicrkrddmtllvlkfe

subfamily_PPM1A_pd Subfamily PPM1A 174-474 7.4e-24 77.6 In-house 10-262 (282) alignment
Range on Protein: 174-474
Range on HMM: 10-262/282.0
INCRYSITETSELSADP-DHYNeDRVFFAKTDDVIVMAVFDGHDGNKASGLVEQYLFSKFINpdvlvglrfetkatlyaliddvervffqkiNDYIEEKN
.. ||.. ...   ..  |...   . .... |    |||||| |....  |.. | .. ..                              .. ..|..
nglrygvssmqgwrvemEDaht.vvaslgalkdwsfFavfDGHaGsevakyvkkhllenile..............................eeelkeaa

DIQSTLPKGLN-------------------------SyqasllypdkinrlqeiepelagGTTAVIAVVFNNNLYVANVGDSRAIAVyRKHfeKFRQLSV
  .|.  . ..                         |                       |.||| ..| ...|..||.|||||. . |.   |   |. 
leasekdevkealrqgfLaldeairelstdlktadks.......................GsTavtvlvsekhliianlGDsRavlc.rng..kaaflte

DHCVDNEDELERLKDLGLDIEQIKRNGRLGsheNTRSIGDYNIKKGYKDVDILSSATgppgiATPSISGPYPINDIEYILLMSDGVYKTLeclTDpptSd
||  ....| .|... |  .   . || |     .|..|||..|.  .        .     | | .     ... ....| .||.. .|   .|   . 
DHkpsrpkEkkRieqAGGsvvvsRvnGaLA...vsRalGDyeykeeeekkaeeqlvs.....aepevtsierseeddflvlacDGiwDvl...sd...e.

vypRLLQLIQKA-EKSANLQDIAREVLQ
    ...|..|  |.. .|. .|.....
...evvelvrkrlevadeleevakalvd

0049733 PP2C-like 191-513 2.8e-28 92.0 In-house 15-233 (235) alignment
Range on Protein: 191-513
Range on HMM: 15-233/235.0
DHYNEDRVFFaktdDVIVMAVFDGHDGNKASGLVEQYLFSKFINP--DvlvGLRFEtkatlyaliddvervffqkindyieE-----------------K
...|||.|..    .....||.||| |  |.... ..|.. ...   .    |  .                                           .
rkvneDavlv....glllfavaDGhgghaagevasellvetllellle...lllld.........................leealrkaflaaneallel

ndiqstlpkglnsyqasllypdkinrLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKhfeKFRQLSVDHCVDNEDELERLKDLGLDIeqik
                           .. ..   .|||||.|..... |||||||||||. . ..   |..||..|| . ||.| .|....|  .    
..........................alaspelagmgtTavvalldggklyvanvGDsrayllrdg...klvqltedhspvnelerqriitaggav....

rnGRLGSHENTRSIGDYNIKkgykdvdilssatgppgiatPSISgPYPINDIEYILLMSDGVYKTlecltdpPTSDVYPRLL-QliqkaeksANLQDIAR
    .|..  ||..||. .|                    | ..  ..... ...||.|||...         ... . .|| .         .|...|.
..rvpgrlaltralGdlllk....................pdvt.vlelepgdflllasDGlwdv.......lsdeeivdllrs........ldleeaae

EVLQDIEAlhkeayydsamtdprstvavnCRKRDDMTLMVLHF
....   |                       .||..|..|...
rlvelala.....................rggrDNiTvvvvrl

PP2Cc_SM00332 192-510 4.6e-34 111.1 In-house 22-273 (274) alignment
Range on Protein: 192-510
Range on HMM: 22-273/274.0
HYNEDRVFFAKT----DDVIVMAVFDGHDGNKASGLVEQYLFSKFINPDVLVGL--RFETKATLYALIDDVERVFFQKINDYIEEKndiqstlpkglnsy
. .||...        .|. ...||||| |.... .| ..|.. ...    .      .... |.  . ...  . .. .   .|.              
ksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen..............

qasllypdkinrlqeiepeLAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHfekFRQLSVDHCVDNEDELERLKDLGLDIEQIkrnGRLGSHENTRSI
                      |.|||.|.. ...|||||||||||. .  .    ..|||||| ...|||..|.|. |  .|.       |. . .|..
...................alsGstavvallkkedlyvanvGDSravlcrngk...avqlsvdhkpedederkRikkaggvvekg...rvngglavsraf

GDYNIKKGYkdvdilsSATGPPGIATPSISGPYPINDIEYILLMSDGVYKtlecltdP----PTSDVYPRLLQLIqkaeksanlqdiA------------
||.  ||         . . |  .|.|...     .. | ..|.|||..                |.  .||.              .            
Gdhflkknk.......klkepyitaepdvkvvtltsedeflilaSDGlwd.......vlsnqevvdivrkllakg............ktndpqeaaelld

REVLQDiealhkeayydsamtdprstvavnCRKRDDMTLMV
.|....                         ...|..| .|
eeairr........................ggseDniTvvv

subfamily_PDP_pd Subfamily PDP 194-394 4.8e-17 55.1 In-house 11-244 (398) alignment
Range on Protein: 194-394
Range on HMM: 11-244/398.0
NEDRVFFAK--TDDVIVMAVFDGHDGNKASGLVEQYLFsKFINPDV-----LVGL--RFETKAT-----------LYALIDDVERVFFQKINDYIEEK--
.||| ..||  . . ....||||| |....  |.. |. |...  .     |.    ..| ...           |    |. ....... ..|..|.  
iEDrrseakllesngvlfgvfDGHggaacaeavskrLl.kyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslselskylqelle

---NDIQSTLPKGLNSYQASL----LYPDKINRLQE-IEPElAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFE--KFRQLSVDHCVDNEDELERLK
   ......| |. ..    .    |   | . |.| ...  . |..|..|.. ...|.|||.||.||.   ...    . ..|| |...|||.|.||.|
aevekvkealkkaFlklDkdistealkklkekslreallva.lsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRik

DLGLDIEQ--IKRNGR-LGSHENTRSIGDYNIKKGY
    . |.  . |||| ||.   .|  ||.. |   
keHPgeesktvirngRlLgeLqPlRAFGdvryKwse

PP2C_2 Protein phosphatase 2C 194-465 1.7e-08 27.0 Pfam-A 12-207 (212) alignment
Range on Protein: 194-465
Range on HMM: 12-207/212.0
NEDRVFFAKTDDVIVMAVFDGHDGNKASGLVEQYLFSKFiNPDVLVGLRFETKATLYALIDDVERVFFQKINdyieekndiqstlpkglnsyqasllypD
..|.... ...|. ..|| ||.   | |    ... . .    .   |  | ...  ||....|.   ....                           .
cqDalaireasdgwllaVADGaGsakrSdkGarlaveaa.gealeklleeeseqeeeallrqieneilasvk...........................l

KINRLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAiaVYRKHFEKFRQLSVDHCVDNEDELERLKDLGLDIEQikrngrlgshentrsigdynikkg
| .. .. |.  . .|| ..||. .........||...  |.|..  ....|. ..  . . |. .|..     |                         
kqeaeaqqeelkdyatTlllavitpgeivffqiGDgai..vvrdrdgevqllgepdsgeyanettfltsedaeeel........................

ykdvdilssatgppgiatpsISGPYPINDIEYILLMSDGVYKTLecLTDPPTSDVYPRLLQLIQKAEKSANL
                         . .... .|||.||| . |   ...|  ... .||. ..... ...|
....................rirrlklepgdalllmTDGvsdsl..rkeepfrellaelletleeegaaeeL

PP2C_2 Protein phosphatase 2C 194-465 1.7e-08 27.0 In-house 12-207 (212) alignment
Range on Protein: 194-465
Range on HMM: 12-207/212.0
NEDRVFFAKTDDVIVMAVFDGHDGNKASGLVEQYLFSKFiNPDVLVGLRFETKATLYALIDDVERVFFQKINdyieekndiqstlpkglnsyqasllypD
..|.... ...|. ..|| ||.   | |    ... . .    .   |  | ...  ||....|.   ....                           .
cqDalaireasdgwllaVADGaGsakrSdkGarlaveaa.gealeklleeeseqeeeallrqieneilasvk...........................l

KINRLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAiaVYRKHFEKFRQLSVDHCVDNEDELERLKDLGLDIEQikrngrlgshentrsigdynikkg
| .. .. |.  . .|| ..||. .........||...  |.|..  ....|. ..  . . |. .|..     |                         
kqeaeaqqeelkdyatTlllavitpgeivffqiGDgai..vvrdrdgevqllgepdsgeyanettfltsedaeeel........................

ykdvdilssatgppgiatpsISGPYPINDIEYILLMSDGVYKTLecLTDPPTSDVYPRLLQLIQKAEKSANL
                         . .... .|||.||| . |   ...|  ... .||. ..... ...|
....................rirrlklepgdalllmTDGvsdsl..rkeepfrellaelletleeegaaeeL

PP2C_SIG_SM00331 195-512 5.9e-09 28.8 In-house 18-216 (217) alignment
Range on Protein: 195-512
Range on HMM: 18-216/217.0
EDRVFFAKTDD-VIVMAVFDGHDGNKASGLVEQYLFS---KFINPDvlvglrfetkatlyalidDVERVFFQKINDYIEEKndiqstlpkglnsyqasll
.| ... |...  ....|.||... .|....   | .   .... .                  .    .....|..|.|.                   
GDyydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellseg..................eelsqalkrlnraiyee...................

ypdkinrlqeiEPELAGGTTAVIAVV--FNNNLYVANVGDSRAIAVYrkhfE--KFRQLSVdhcvdnedelerlkdlgldieqikrngrlgshentrsig
           . |  ...|...|..   ...|..||.|||| . .     .   . .|.                                        
...........keekgmfaTlllalydfssgklsyanaGdsrpyllr....dgklveilkd.......................................

dynikkgykdvdILSSATGPPGIATPSISGpYPINDIEYILLMSDGVYKTLECLTdpptsdVYPRLLQLIQKAEKSANLQDIAREVLQDIEALHKEAYYd
            ... ..|     .. |.    ..  . .||..||.    .  .      .    |..| ..  .  .|..|.. ......| |.. . 
............vegaplGlepevsvdire.lelekgdllllytDGltearsekg......faeerleeiledlvdseaqelaqkiveellelakgsng.

samtdprstvavncrkRDDMTLMVLH
                .||.|..|. 
................eDdiTvvvvk

subfamily_PPM1G2_pd Subfamily PPM1G2 201-438 4.4e-23 74.6 In-house 47-235 (287) alignment
Range on Protein: 201-438
Range on HMM: 47-235/287.0
AKTDDVIVMAVFDGHDGNKASGLVEQYLFSKFINpdvlvglrfetkatlyaliddvervffqkiN-DYIeeKNDIQSTLPKGLNSYQASLLYPdkinrlQ
  .... ..|||||| |.|..  . . | .|  .                              . ..   .. ..  | ... .   .||        .
sddkslalfavfDGhGGakvakyagkklikkiak..............................kksfk..egaleqilkdafletDeellkd......e

EIEPELAgGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHfekFRQLSVDHCVDNEDELERLKDLGLDIEQIKRNGRLGShenTRSIGDYNIKKGYKDVDI
... | | |.|||.... ...|||||.|||||..  . .    ..||.||  ..|.| .|... |  .|  . || |      |..||.. ||. |    
klkdesa.GstavvvlikeeklyvanaGDsravlsskgn...vkalsfDhkPqeesekkriiaagGfvelnrvngnLal...sralgDfefkknvkkkpe

LSSATGPPGIATPSISgpypiNDIEYILLMSDGVYKTLE
    |  | . . ...     .| |...|  ||..  |.
eqivtavPDvlvkkld.....eddeflvLaCDGiWDvlt

subfamily_PPM1H_pd Subfamily PPM1H 201-364 2.1e-13 42.8 In-house 57-214 (404) alignment
Range on Protein: 201-364
Range on HMM: 57-214/404.0
AKTDDVIVMAVFDGHDGNKASGLVEQYLFSKFIN--PDVLVGLRFETKaTLYALIDDVERVFFQKINDYIEEKNDIQSTLPKGlnSYQASLLYPDKINRL
... .. . ..|||| |. |. .  . | ..  .   |||  |  . . .     .....   .. ..  |||.  . .| .|  .   . |  |.  . 
eeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksa.eeeenteesskespssvseiyeekeiskeeLviG..alesaflemDeqiar

QEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVyrkHFEKFRQLSVDHCVdnEDELERLKDLG
.. . ...|| ||..|.|... ||||| |||||| |   . .. ..|| |.    | | .||. |.
ereayrikGGCtalvalvllgklYvanaGDsRailv...rkdeiiplsadftP..eteRqRlqela

subfamily_PPM1D_pd Subfamily PPM1D 202-369 2.2e-12 39.7 In-house 31-173 (309) alignment
Range on Protein: 202-369
Range on HMM: 31-173/309.0
KTDDVIVMAVFDGHDGNKASGLVEQYLFSKFINPDVLvglrfetkatlyaliddvervffqkindYIEEKNDIQSTLPKGLNSYQASLLYPDKINRLQEI
.. .| ..|||||| |..|.  . . |.|.  . . .                            . .|..|... . ..  . . ..    .    .. 
eelevafvavfDGHGGkeAakfarehlwsvikkqkkf............................lssepedvleAireaflatheamkkkleeWpktks

EPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKH---FEKFRQLSVDHCVDNEDELERLKDLGLDIEQ
      |||| . .. ...||||.||||...  ....   . . ..| .||  .. .| ||...|| .. .
gllstaGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGevaa

subfamily_PPM1L_pd Subfamily PPM1L 206-393 7.6e-13 41.3 In-house 35-190 (269) alignment
Range on Protein: 206-393
Range on HMM: 35-190/269.0
VIVMAVFDGHDGNKASGLVEQYLFSKFINPDVLVglrfetkatlyaliddvervffqkindyieeKNDIQSTLPKGLNS-YQASLLYPD-KINRLQEIEP
  ..|||||| |. |.  ... |  .  |  . .                               ..| . |.|   .   .  .|  | |.    . . 
esffavfdGhGGefaaefakdvlvkaiknkliel...............................dadkentepinfsklltdeilsvdekllekakrae

ELAgGTTAVIAVVFNNNLYVANVGDSRAIAVYRKhfEKFRQLSVDHCVDNEDELERLKDLGLDIEQIKRNGRLGSHENTRSIGDYNIKKG
..| ||||.||.| ...| |||||||| . . ..   |   || ||   .  |  |.|. |  |         |    .|..||| .|. 
dia.GttalialvqesdlivanvGdsrGvlydkr..GkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplkdk

PPM_PTC7_SpoIIE 249-513 4.4e-16 52.4 In-house 69-229 (230) alignment
Range on Protein: 249-513
Range on HMM: 69-229/230.0
LYALIDDVERVFFQKINDYieekndiqstlpkglnsyqasllypdkinrlqeiepELAGGTTAVIAVVFNNN--LYVANVGDSRAIAVYRKHFekfrqls
. ... . .. ......|.                                    .  .|.|||.|......  |||||.|||... |  ..        
peeilrrlnlalaadlede....................................psssgaTavvalidpstgklyvanaGdsppllvrddgg.......

vdhcvdnedELERLkDLGLDIEqI--KRNGRLGSHENTRSIGDYNIKKgykdvdilssatgppgiatpsisgpypindieyillmSDGVYktlECLTDPP
         | ||. ..|  .. .    .   |... ....||. ..                                      .|||    |.  | .
.........ereri.vagglps.lGilpgrvfgvlavslapGdlllly.....................................tDGvv...eaepdts

TSDVYP--RLLQLIQKA--EKSAnLQDIAREVLQDIEALhkeayydsamtdprstvavNC--RKRDDMTLMVLHF
.   .   ..|.|. ..  ..   .|.... |....|..                   ..  ...||.|| |...
dgelfgkdeflilasdglwdvls.pqelvdlvrdelekp...................aaeglleDDitllvvrv

PPM_PTC7 253-437 3e-32 105.1 In-house 45-221 (259) alignment
Range on Protein: 253-437
Range on HMM: 45-221/259.0
IDDVERVFFQKINDYIEEKNDIQST-LPKGLNSYQASLLYPDKINRLQEIE-PELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEkfRQLSVDHC
.. ..... ..... ..|. . ... ...   . .   |. |. ....|    .. .|.|||.|......|||||||||||. . ....    ||..|| 
greaakyarehleeilkerksfeeleklekalrksflaldtdeelksseantepstsGstAvvalitgsklyvAnvGDSravLcrsgnav..kqltedHk

VDNEDELERLKDLGLDIEQIkRNGRLGSH-ENTRSIGDYNIKKGYKdvdilssaTGPPGIATPSISGPYPINDIEYILLMSDGVYKTL
..|||| ||....|  .... .|||.    ...|..||.  |....        . .. .|.| ||     .. |...|.|||..  .
psnedEreRiegaggsvsnv.gngrvngvlavsRafGdfelkpket........eeqlvsaePdisstkideedefliLasdGlwdvv

subfamily_KAPP-like_pd Subfamily KAPP-like 256-436 1.7e-10 33.4 In-house 52-218 (266) alignment
Range on Protein: 256-436
Range on HMM: 52-218/266.0
VERVFFQKINDYIEEkndiQSTLPKGLNSYQASLLYPDKINRLQE-IEPELAGGTTAVIAVVFNN----NLYVANVGDSRAIAVYRKhfEKfRQLSVDHC
 ...| .........          | | |. | |. . .. ... ..     |.|| .|.|...     | ||||||| |.  .    |   .|| || 
akklfpkelekllks....tkqddGGdniydqskllenafkevdaklkdfeyeGatatlalvwsdGqqrylqvanvGdssaflsrGn..es.lelskdhk

VDNEDELERLKDLGLDIEQikRNGRLGSHENTRSIGDYNIKKgyKDVDIlssatgppgIATPSISGPYPINDI-EYILLMSDGVYKT
 ....|  |.|| |. . .   . |.     .|..||. ||.  ... .         |..| .| .. .    ..... |||..  
akdpeekqrikddGitlsd..nqtrinGlavsralGdhfike..lniGl.........isepyvsnrilltpfdkflivasdGlwdv

subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 256-436 1.6e-08 26.7 In-house 51-228 (276) alignment
Range on Protein: 256-436
Range on HMM: 51-228/276.0
VERVFFQKINDYIEEKN-DIQSTLPKGLNSYQASLLYPDKINRLQ-EIEPELAGGTTAVIAVVFNNN----------LYVANVGDSRAIAVYRKhfEKfR
 ...| .... ...  |  .      | | |. | |. | .. .. ...     |.|| .|.|...           | ||||||| |.  .    |   
akklfpkelekllksgnysltkqddGGdniydqskllldlfkevdaklkdfeyeGatatlalvwsdGeeqqqqqqrylqvanvGdssaflsrGn..es.l

QLSVDHCVDNEDELERLKDLGLDIEQikRNGRLGSHENTRSIGDYNIKKgyKDVDIlssatgppgIATPSISGPYPINDI-EYILLMSDGVYKT
.|| ||  .. .| .|.|| |. . .   . |.     .|..||. ||.  ... .         |..| .| .. .    ..... |||..  
elskdhkatdpeekqrikddGitlsd..nqtrinGlavsralGdhfike..lniGl.........isepyvsnrilltpfdkflivasdGlwdv

PP2C Protein phosphatase 2C 258-437 5.8e-29 94.4 Pfam-A 50-216 (255) alignment
Range on Protein: 258-437
Range on HMM: 50-216/255.0
RVFFQKINDYIEEKNDIQSTLpKGLNSYQASLLY-PDKINRLqEI--EPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEkfRQLSVDHCVDNE
... ..... ..|. . ..   |  .  . | |   |. ... ..  . ..  |.|||.|......|||||||||||. . .....   .|..|| ...|
kyarehleeilkeqksflele.kvekalrksfladtdeelks.skantepsksGstavvalirgkklyvAnvGDSravLcrkdnak..keltedHkpsde

DELERLKDLGLDIEQikrNGRLGSH-ENTRSIGDYNIKKGYkdvdilssatGPPGIATPSISGPYPINDIEYILLMSDGVYKTL
|| ||....|  ...   |||.    ...|..||. .|...           .. .| | ..     .. |...|.|||..  |
dEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpke..........eqlvsaePdvtsvklteedefliLasdGlwdvl

PP2C Protein phosphatase 2C 258-437 5.8e-29 94.4 In-house 50-216 (255) alignment
Range on Protein: 258-437
Range on HMM: 50-216/255.0
RVFFQKINDYIEEKNDIQSTLpKGLNSYQASLLY-PDKINRLqEI--EPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEkfRQLSVDHCVDNE
... ..... ..|. . ..   |  .  . | |   |. ... ..  . ..  |.|||.|......|||||||||||. . .....   .|..|| ...|
kyarehleeilkeqksflele.kvekalrksfladtdeelks.skantepsksGstavvalirgkklyvAnvGDSravLcrkdnak..keltedHkpsde

DELERLKDLGLDIEQikrNGRLGSH-ENTRSIGDYNIKKGYkdvdilssatGPPGIATPSISGPYPINDIEYILLMSDGVYKTL
|| ||....|  ...   |||.    ...|..||. .|...           .. .| | ..     .. |...|.|||..  |
dEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpke..........eqlvsaePdvtsvklteedefliLasdGlwdvl

subfamily_PPM1K_pd Subfamily PPM1K 260-392 7.8e-12 37.9 In-house 53-183 (263) alignment
Range on Protein: 260-392
Range on HMM: 53-183/263.0
FFQKINDYIEEKNDIQSTLPKGLNSYQASLLYPDKINrLQEIePELAGGTTAVIAVVFN-NNLYVANVGDSRAIAVyRKhfEKFRQLSVDHCVDNEDELE
. . .... |. .|..  | . ..  .  |    . . . |   .|. |||| .... . ..| .|..||||||   |.   | ..|. ||  . |.| |
lekilkrllekekdleivlknafeeldkklkrylefs.vaea.ellssGttatvsllrdGtelvlaslGdsrailc.rn..GkakkltrdhdPeleeeke

RLKDLGLDIE-----QIKRNGRLgshENTRSIGDYNIKK
|.|  |  .|     . . ||||     |||.|| ..|.
rikaagGsvewnslgkplvngrl...amtrslGdldlkr

subfamily_PPM1E_pd Subfamily PPM1E 283-392 5.1e-14 45.1 In-house 78-184 (265) alignment
Range on Protein: 283-392
Range on HMM: 78-184/265.0
NSYQASLLYPDKINRLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKhfeKFRQLSVDHCVDNEDELERLKDLGLDIEQIKRNGRLGSHENT
.  . ..   |.    . .. .| .|.|||.... ...|||| .|||.|. |      ...||   |  ..||| .|....|  . .|      |.   .
ealkeafkltDerflqkaereklksGstavvvliekdqlyvaWlGDsqallvrkg...eavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvs

RSIGDYNIKK
|.|||.. |.
RaiGDvklkp

subfamily_ILKAP_pd Subfamily ILKAP 299-465 4.5e-15 48.5 In-house 105-252 (293) alignment
Range on Protein: 299-465
Range on HMM: 105-252/293.0
QEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEK---FRQLSVDHCVDNEDELERLKDLGLDIeqikRNGR-LGSHENTRSIGDYNikkgY
.. .|    |.||.. .| .| |||||.|||.|. | .|.  .   . .|..||   ...| .|..  |  .    |.|| ||  | .||||| .    .
skakPvWkdGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaGgvv....rdgrvlGvlevsrsiGdgr....f

KDVDIlssatgppgIATPSISGPYPINDIEYILLMSDGVYKTLEcltdppTSDVYPRLLQLIQKAEKSANL
| . .         |.|| ..     ..  ...|  ||..|...      ...|    |......|.. ..
krlGv.........istPdvkkceLtendlfvvlaCdGLwkvfs......adevvkfilkvledeeddrki

subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 301-371 1.1e-08 27.9 In-house 79-152 (292) alignment
Range on Protein: 301-371
Range on HMM: 79-152/292.0
IEPELAGGTTAVIAVVFNN-NLYVANVGDSRAIaVYR---KHFEKFRQLSVDHCVDNEDELERLKDLGLDIEQIK
|.  . ..|..| |.| .. .|..||||||||. ..|       . . || ||  .. || .|..  |  .|  .
idaresattavvcarvrddralilanvGdsral.lgrclggsdyeliPlsrdhkPedPderarilraGGrveptr

subfamily_PPM1G_pd Subfamily PPM1G 302-437 2.6e-14 46.1 In-house 291-416 (473) alignment
Range on Protein: 302-437
Range on HMM: 291-416/473.0
EPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRkhfEKFRQLSVDHCVDNEDELERLKDLGLDIEqikRNGRL-GSHENTRSIGDYNIKKGyKDVDIL
||    |||||.|.. ...|.|||.||||..        |  .||.||  ..| ||||..  |  ..    .||. |     | .||.. ||  ....  
epGedsGttAvvaLlkekklivAnaGDsRcvlsrn...GkAldlslDHkPeDevEleRiekAGGkvd...edgRvnGGLnlsRAlGDhaYkkn.eeLplk

SSAtgppGIATPSISGPYPINDIEYILLMSDGVYKTL
         | | |      .. |.. | .||.. ..
eqm....isAlPDikvltlteedeFlvlAcDGiWnvm

subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 305-389 4.3e-11 35.6 In-house 93-176 (255) alignment
Range on Protein: 305-389
Range on HMM: 93-176/255.0
LAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEKfrQLSVDHCVDNEDELERLKDLGLDIEQIKRNGRL-GSHENTRSIGDYN
   ||||. ... ..  |.|||||||..   ..   |  .||.||   .|.| .|...||  . . .   |. |    .|..||  
kfiGttaasvliiedkvyianvGdsrvvlcqkdgtak..rlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsf

subfamily_PP2D1_pd Subfamily PP2D1 318-388 5.1e-06 18.5 In-house 187-255 (492) alignment
Range on Protein: 318-388
Range on HMM: 187-255/492.0
NNNLYVANVGDSRAIAVyRKhfEKFRQLSVDHCVDNEDELERLKDLGLDIEQIKRNGRL-GSHENTRSIGDY
   ||.||.|. .|. . |.   |  .|  .|   |. | .|..  |  . . ..||.  |  ..|| .| |
lgvlyianaGnvqAvLc.re..GkaiiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGny

SpoIIE Stage II sporulation protein E (SpoIIE) 424-513 5.7e-07 21.5 Pfam-A 125-192 (193) alignment
Range on Protein: 424-513
Range on HMM: 125-192/193.0
EYILLMSDGVYKTLecltdppTSDVYP----RLLQLIQKAeKSANLQDIAREVLQDIEAlhkeayydsamtdprstvavNC--RKRDDMTLMVLHF
. .||..|||. .        ..|       |||.|...| ....|............                     ..  ...||.||.||..
dllllyTDGvtEar.......dpdgelfgkerllallaea.egesleelldalveelle....................lgsgeleDDitllvlrv

SpoIIE Stage II sporulation protein E (SpoIIE) 424-513 5.7e-07 21.5 In-house 125-192 (193) alignment
Range on Protein: 424-513
Range on HMM: 125-192/193.0
EYILLMSDGVYKTLecltdppTSDVYP----RLLQLIQKAeKSANLQDIAREVLQDIEAlhkeayydsamtdprstvavNC--RKRDDMTLMVLHF
. .||..|||. .        ..|       |||.|...| ....|............                     ..  ...||.||.||..
dllllyTDGvtEar.......dpdgelfgkerllallaea.egesleelldalveelle....................lgsgeleDDitllvlrv

PPM_PTC7_SpoIIE_motif 425-513 3.9e-08 26.9 In-house 14-80 (81) alignment
Range on Protein: 425-513
Range on HMM: 14-80/81.0
YILLMSDGVYktlECLtdppTSDVYP----RLLQLIQKAeKSANLQDIAREVLQDIEAlhkeayydsamtdprstvavNC--RKRDDMTLMVLHF
 .||..||..   |.     .||       .||.|...| .. .||..|.........                    |.  ...||.||.||..
vllLyTDGlt...Ear....dsdgelfgkeellrladra.egkslqeladklvdevle....................ngsgereDDitllvlrv