Gene C27B7.6 in Caenorhabditis elegans

Synonym: CELE_C27B7.6, C27B7.6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily CelePPP-sf3
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP028_AA protein Get Run
CeleP028_AA_21-307 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 17-304 9e-170 556.1 In-house 2-290 (290) alignment
Range on Protein: 17-304
Range on HMM: 2-290/290.0
QMIARIEKYGTLEGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFS
.|| ...|||.|..|||.||||.|..|.|||||||.|.|..||.|..|||||||..||.....||.||....||||||||||..||||...|||.||..|
rmiehllkygvldafsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykirys

KKVHLLRGNHEVRRVNTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHGDCEHGLIVDLIWSDPNR-K
|||||||||||||.||..||||||..|||.|.|||...|||||||.||...|||||||||||.|||||.||....||||...|..||.|||.|.||.| |
kkvhllrgnhevrkvnrlygfkeelarkrgsrlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdk

DDTIQFNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPNK
||||..||.|.||..|||...|.|...||..||.||||.||.|..|.||..|.||||||||||...|||..||.|.||.|.||.|||.|
ddtialnkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlkprk

subfamily_PPP2C_pd Subfamily PPP2C 20-302 4e-66 216.1 In-house 6-285 (290) alignment
Range on Protein: 20-302
Range on HMM: 6-285/290.0
ARIEKYGTLEGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKV
. |||    . ...|.. |. . .||||.    . |. .|| | ||.|||. |||.. .  |. || .|||||||||||  |.|   .| ..|. . ...
klieklkeckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvrykeri

HLLRGNHEVRRVNTMYGFKEEMMRKR-NSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTkpRVHGDCEHGLIVDLIWSDPNrkDDT
 .|||||| |..  .||| .| .||  |. .||.| |.|  |...| ....|.|.|||.||.|.. | .  .   |.    . | ..||.||||.  | .
tilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkirald..rlqevphegplcdllwsdpd..drg

IQFNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKP
      ||    ||| . ...  |  . ||.|||..  .|. . .|... |.|||| |     | ...  . ..|| .... .|
gwgisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdp

subfamily_PPP4C_pd Subfamily PPP4C 21-294 6.9e-66 215.4 In-house 6-276 (288) alignment
Range on Protein: 21-294
Range on HMM: 6-276/288.0
RIEKYGTLEGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVH
.|||  . |  ..... .. . ..|||     . .. .||.| ||||||. |||.. .  |  |. .||||||.|||| .|.|  . | ..|. . ....
qieklrrcelikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdrit

LLRGNHEVRRVNTMYGFKEEMMRKR-NSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTkpRVHGDCEHGLIVDLIWSDPNRKDdTI
|.||||| |..  .||| .|..||  ....|..  .||  ||..| |. ||.|.|||.||.|.. | .  .   | .   ..| ..||.||||. .. . 
lirgnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsid..rkqevphegplcdllwsdpedae.gw

QfNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLK
     ||   |||..||......  |.||.|||..  .|. . |....|||.||| |     |. ..  . ..|.
a.vsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeld

subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 22-308 3e-158 518.2 In-house 1-287 (287) alignment
Range on Protein: 22-308
Range on HMM: 1-287/287.0
IEKYGTLEGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHL
..|||.|..|||.||||||..|.|||||||.|.|..||....|||||||.|||...|.||..|..||||||||||||..||||...||..||...|||||
llkygvldafsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhl

LRGNHEVRRVNTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHGDCEHGLIVDLIWSDPNRKDDTIQF
|||||||...|..||||||..|||...|.|.|||||.||..||.....|||||||||||..|.|||....||.....|..||.|||.|.||.....|...
lrGnhevkkinklyGfkeelkrkrqerlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfel

NKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPNKGYDR
||.|.||..|||..||.|...|.||||.||||..|.|..|.||.||.||||||||||...|||.|...||||.|..|.|||.....|
nkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpedfevr

0049330 Metallo-dependent phosphatases 22-304 2.5e-81 266.2 In-house 21-300 (309) alignment
Range on Protein: 22-304
Range on HMM: 21-300/309.0
IEKYGTLEGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHL
||.. .|  .| ...|..|  .||||   | |.|. ...||.||||||| |||.  . .| ||. ...||||.|||||.||||  .|...|.|. ..|.|
ielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalkllypdnvfl

LRGNHEVRRVNTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHGDCehGLIVDLIWSDPNRKDDTIQF
|||||| | .| .|||..|..|| ...||. |.|... | ..| |. ||||.|||.|| . ..|..  . .|.   .   ||..||.||||..  .... 
lrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipld..gllcdllwsdplpiregfap

NKmRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPNK
|. ||.. .||  .|....... .|||||.|.. . |. . ||..|.|||||| | |...|||.| .|...|........| .
np.rglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvp

0053225 Metallo-dependent phosphatases 22-302 4.4e-74 242.5 In-house 13-290 (293) alignment
Range on Protein: 22-302
Range on HMM: 13-290/293.0
IEKYGTLEGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHL
|| . .|  .| ...|..| ..||||   | |.|. ....|.|||||.| |||.  . .| ||. ...||||.|||||.||||  .|...|.|. ..|.|
ielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkllypdnvvl

LRGNHEVRRVNTMYGFKEEMMRKR-NSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHGdcEHGLIVDLIWSDPNRKDDtiQ
|||||| . .| .|||..|..||  ...||. ..|... | ..| |. |||..|||.|| . ..|..  . .|      ..||. || ||||.. ..   
lrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplrip..legllldllwsdpdlwsg..w

FNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKP
  ..||.. .||  .|......  .|||||.|..   |... ||..|.|||||| | |...|||.| .....|. ......|
lpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfap

0045823 Metallo-dependent phosphatases 23-307 1.9e-85 280.3 In-house 35-328 (473) alignment
Range on Protein: 23-307
Range on HMM: 35-328/473.0
EKYGTLEGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLL
| . ... .. .|.|..|. .||||   | |.|. ...||.||||||| |||.  . .|.||. ...||||.|||||.||||  .|...||.. ..|.||
ehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkikypgnvfll

RGNHEVRRVNTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHGDceHGLIVDLIWSDPnRKDDTI---
||||| | .|..|||..|...| . .|.. |..... | ..| |. |||..|||.|| ....| .  . .|. . |  .||..|| ||||   ||     
rGNHElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipd..dgllldllwsdP.weddgdgll

----QFNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNR------LLTVFSAPYYSGHNSNLGSVATISKSLkLRIVTLKPNKGYD
      |  ||.. |||. .|....    .|||.|.|.. . |. . ||..      ..|||||| | |.. ||..|..|.. | . .....| .   
rlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsphpl

subfamily_PPG1_pd Subfamily PPG1 23-293 3.4e-61 200.1 In-house 6-286 (300) alignment
Range on Protein: 23-293
Range on HMM: 6-286/300.0
EKYGTLEGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLL
||    | . .. . |. . .||.|     .||| .|| | ||.|||. |.|.  .  |. || .|||||||||||  |.|  . | ..|. .  ...||
eklqkaellpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritll

RGNHEVRRVNTMYGFKEEMMRKR--NSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTkpRVHGDCEHGLIVDLIWSDPN-------
||||| |..  .|||  | .||   ||..|| . ..|  |...| |. .| |.|||.||.. | | .  .   | .   ..| . ||.||||.       
rgnhesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvld..rfrevpnegaladllwsdpeennnptl

-RKDDTI-QF-NKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSL
 . |.   .| .  ||    .||.|| ..  .  .. |||||..  .|.   |||.| ||.||| |     |  |.  . . .
dhpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekd

subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 24-304 9.6e-86 280.5 In-house 17-295 (298) alignment
Range on Protein: 24-304
Range on HMM: 17-295/298.0
KYGTLEGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLR
.    .  ...|. ..... |.|..  . |.|. ||. | ||||||  |||.. .. | |||  ||||||||||| ..||| | |.. |. . ... |||
ekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnffllr

GNHEVRRVNTMYGFKEEMMRKR-NSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRvhGDCEHGLIVDLIWSDPNRKDDTIQFN
||||.  .| .|||.||. |.  . .|.. |.|||. | ..| |  .|||||||.|.|..|.|.|  ...|    . |. | .||.|.||...    . |
GnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpf..dskeeslaidllwadpenavkgwaen

kMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPNK
  ||.|. ||. || .|. .| |||..||| .   |. |  ...|.|.||||.| |.  |  .| .... |..  . |||.|
.srGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkpek

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 28-83 4.1e-06 19.1 In-house 8-63 (339) alignment
Range on Protein: 28-83
Range on HMM: 8-63/339.0
LEGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRP
|. |  ... |. .  .|..   | .... ||..|.||||||. ||| . .  | |
ldlfcaaelaelchrareliwsepiflkleapicvmgdihgqfddllamldmngwp

subfamily_PPP6C_pd Subfamily PPP6C 29-293 1.3e-62 204.6 In-house 13-274 (290) alignment
Range on Protein: 29-293
Range on HMM: 13-274/290.0
EGFSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEV
. ....|. .. ......|     .  . .|| | ||||||. ||... .  |. || .|.||||.||||  |||    |...|. . ... ||||||| 
kylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhes

RRVNTMYGFKEEMMRKR-NSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTkpRVHGDCEHGLIVDLIWSDPNRKDDTIQfnKMRGI
|..  .||| .| ..|  |.  || . .||  |.|.| |. ..||.|||.||...  |... ..  | .   ..| ..||.||||.  ..  .    || 
rqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvie..raqeiphkgafcdlvwsdpedvetwav..sprga

STLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSL
  |||..|.......  ..||.|||.. |.|  . ||..| ||.||| |     |. |. ..... 
gylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledae

subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 31-302 3.5e-68 223.1 In-house 8-282 (284) alignment
Range on Protein: 31-302
Range on HMM: 8-282/284.0
FSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRP------PDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRG
... ...|.    .|..   .  .|| ||| . ||||||  |||.. .  | |       . .|||||||||||| |.|| . ||..|.|. .|| ||||
lkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrg

NHEVRRVNTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHGDCehGLIVDLIWSDPNRKDDTIQfNKM
||| | ||  ||| .|  ..    |...|.  |  . .|| ...||.||||||| .. . . |  . .|    |   |.| || |.||. . .. . .  
nhesrpvnmqygfyleckkrysealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdi..gviadltwadpeaevegyk.esp

RGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKP
||   .||.. |.... .  .||..|||..   |. |  |..|.|.||||.| |.  |...| .... |   ...|||
rgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlkp

subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 31-304 3.7e-64 209.8 In-house 6-301 (302) alignment
Range on Protein: 31-304
Range on HMM: 6-301/302.0
FSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGR------PPD-----FQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKV
.| |..| ..... | |.    |.|| .|| . ||||||  ||..  |.          .       ...|||||||||..|.|    .|..|.|. .. 
ysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptny

HLLRGNHEVRRVNTMYGFKEEMMR----KRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPrVHGDCEHGLIVDLIWSDPNRK
 |||||||.. .|  |||.||.      |   ..|. ||.||. . . | . .||||.|||||||.||..... ...| ..   |  |  ||...||   
illrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrp.lkevtedslaqdllfadpldv

D--------DTIQFNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPNK
.           ..| .||.| .| .. | ..|  | ..||.||| |  .|. |  |..|||.|||| |     | |.|  .    || | .|...|
qllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrnkk

subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 31-303 6.9e-64 208.9 In-house 7-301 (302) alignment
Range on Protein: 31-303
Range on HMM: 7-301/302.0
FSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGR------PPD-----FQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKV
.| |..| ..... | |.    |.|| .|| . ||||||  ||..  |.          .       ...|||||||||..|.|    .|..|.|. .. 
ysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptny

HLLRGNHEVRRVNTMYGFKEEMMR----KRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPrVHGDCEHGLIVDLIWSDPNRK
 |||||||.. .|  |||.||.      |   ..|. ||.||. . . | . .||||.|||||||.||..... ...| ..   |  |  ||...||   
illrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrp.lkevtedslaqdllfadpldv

D--------DTIQFNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPN
.           ..| .||.| .| .. | ..|  | ..||.||| |  .|. |  |..|||.|||| |     | |.|  .    || | .|...
qllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrnk

subfamily_PPP3C_pd Subfamily PPP3C 31-291 5.4e-63 206.3 In-house 41-311 (452) alignment
Range on Protein: 31-291
Range on HMM: 41-311/452.0
FSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRR
......|.....  ..|.  . |.|. ||..| ||||||  |||.. .  | | . .|||||||||||  |.|. ..|...|| ......||||||| | 
leeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecrh

VNTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTkpRVHGDCEHGLIVDLIWSDPNRK------DDTIQFNKM
.   . ||||.  | . .... . . |  | . | .|.. ||.|||.||.|.| |..  .   | .   ..|.. ||.||||  .      ... . |..
lteyftfkeeckikyseevydacmesfdslPlaallnqqflcvhGGlspeikslddikkld..rfkeppasGplcdllWsdPledygeekteekfvpnsv

RGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDN------RLLTVFSAPYYSGHNSNLGSVATISK
|| | ... . | ..  .  .  |||||| ...|..   ..       |.|.|||| | .  .| ..|  . .
rGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyen

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 31-83 1.9e-06 20.3 In-house 9-61 (317) alignment
Range on Protein: 31-83
Range on HMM: 9-61/317.0
FSDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRP
|......|.    .|..   |  .|. ||| . ||||||  ||| . .  | |
fkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwp

PP2Ac_SM00156 32-304 1.4e-108 355.1 In-house 2-271 (271) alignment
Range on Protein: 32-304
Range on HMM: 2-271/271.0
SDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRV
|....||.|...||||.  ..|.|. |||.|.||||||| |||..... |.||. .|.||||||||||.|.|| ..||..|||...||.||||||| ..|
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssv

NTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKprVHGDCEHGLIVDLIWSDPNRKDDTIQFNKmRGISTLF
|..|||.||..|| .......|...|. |...| ...||||||||.||..||.|... ...  |. ..|.||..||.||||..|....|..| ||.|..|
nkiygfeeevkrkygkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkr..vkekpeegllidllwsdpeqkekgfqpsk.rglsvvF

GKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPNK
|...|..........|||||||....|..|..|..|.|.||||.| ...||...|....|.|||.|..||..|
gedavkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlkeqk

subfamily_PPP1C_pd Subfamily PPP1C 32-304 8.6e-89 290.4 In-house 11-280 (282) alignment
Range on Protein: 32-304
Range on HMM: 11-280/282.0
SDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRV
. ..| ..||. .|||   | |.|. ||| ..||||||. |||.. .  | ||. .||||||||||| .|||. | |...|| ......|||||||   .
keaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesasi

NTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHGdcEHGLIVDLIWSDPNRKDDTIQFNKmRGISTLF
|..|||..|. |. ...|||.|.|||. | ..| .. ||||.|||.||...| . .. ...|      |.||..||.||||...  ... |. ||.|  |
nriyGfydeckrrysiklWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevp..ekgllcdllWsdpdkevlgwsend.rGvsftf

GKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPNK
||.||.....   .|||.|||.. |.|. |  ...|.|||||| | |.  | |.| .....|...   |||.|
gkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilkpak

subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 32-303 1.2e-76 250.5 In-house 7-275 (280) alignment
Range on Protein: 32-303
Range on HMM: 7-275/280.0
SDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRV
 . || .|... |.||    ...|. ||| | ||.|||  |||.. ..|. ||| .|||||||||||   ||| . |.. |. . ..  .||||||| ..
keadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevisi

NTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRvHgDCEHGLIVDLIWSDPNRKDDTIQfNKMRGISTLF
|  ||||.|..|. . .|.. |.... .| ..| .. .|||||||.|.|. |.| |. ...|  .   .. |  ||.|.||. |      .. ||.|..|
nrkygfkdevkrryslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpf.d.sedeclamdllwadpenkvtgwa.ensrgvsvif

GKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPN
|. || .|.  | ||||.| |.. . |. |  |..|.|||||| | |. .|  .|  ... |.. .  |||.
ganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkpa

subfamily_PPZ_pd Subfamily PPZ 32-301 3e-67 220.2 In-house 26-292 (300) alignment
Range on Protein: 32-301
Range on HMM: 26-292/300.0
SDSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRV
 .|.||.. .  .|..   |.|.|.  .| . ||.||| .|||..  ..| ||  .||||||||||| .|||  . |.| || . ... |||||||.  |
knseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnhecanv

NTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHGDceHGLIVDLIWSDPNRKDDTIQFNKmRGISTLF
  .||| .|  |. | ..|| | | |  | ..| .  ||.|.|||.|| ..| | .  ...|    |   ||| ||.||||    .  . |. ||.|  .
trvygfydeckrrcnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpd..fglindllwsdptdssnewedne.rgvsycy

GKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLK
 |  ....   . .||. ||| . | |. |  |  |.|||||| | |   | |.| ..|. |   .  | 
nkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfelld

subfamily_PPP5C_pd Subfamily PPP5C 32-299 1.4e-63 207.9 In-house 35-305 (322) alignment
Range on Protein: 32-299
Range on HMM: 35-305/322.0
SDSDILEVLKTIKEILEPLPCLIEIIAP----VVVFGDIHGQLGDLLQFTNEVGRPP-DFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNH
    .|..|...||.|. ||.|.||  .    . | ||||||  |||   .  |.|  .  ||| ||.||||  |.|| . |...|.|. ....| ||||
hkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrGnh

EVRRVNTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIE-SWDSLTGMtkPRVHGDCEHGLIVDLIWSDPNRKDDTIqfNKMR
|  ..| .|||..|.  | .... ..|..||  | ..  || |.| .|||.  . . . | |  .   | . . |.||.|.|.||||...  .   . .|
esdnmnklyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrki..drnaqppeegllvellwsdpqeanGrs..pskr

GISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATI-SKSLKLRIVT
|... ||  | .... .  ..||||.||.||.|. .| | .|.|||||| |  . .|.|.. |. .. |||.. |
GvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfkt

PPP_3 33-300 2.6e-96 314.8 In-house 4-269 (271) alignment
Range on Protein: 33-300
Range on HMM: 4-269/271.0
DSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVN
 ... |..|..|||||  ..|.|| |||.|.||||||| |||......|..|. .||||||||||| .|||| ..|...||...|.||||||||| |..|
enelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrqin

TMYGFKEEMM-RKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHgdCEHGLIVDLIWSDPNRKDDTIQFNkMRGISTLF
..||||.|.. .| .....|....||. |...| |..|.|..|||.||.|.|.|... .......  .|.|...|| .|....|..... .  ||...||
kvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkiev..peegklldlllssdpekeeglens.krGagllF

GKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTL
|..|.......  ..|||||||.||.|.....|....|||||| | ...||.|........|. ....|
gpdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkql

subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 33-303 3.4e-75 245.9 In-house 10-277 (281) alignment
Range on Protein: 33-303
Range on HMM: 10-277/281.0
DSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVN
. .| .|.. .. |.     |.|| .|.|| ||.|.|  || .  . .||.|. ...||||||||||.|||| . ||..|| . ... |||||||. .||
keeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasvn

TMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPrvHGDCEHGLIVDLIWSDPNRKDDTiQFNKMRGISTLFG
 .||| .| . |    ||  |.  | .| | | |....||||||.||.. . | |  . ||    . . ||..||.|.||. |     .. .||.| .||
kiygfyvecvtkyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkp..irnldrGlviDllwadpdnkvee.wkassrGssftfG

KSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPN
|.|||. | .| ..|||||| .   | .     .|.||||.| |  .  | ..| .. ..|....|.| |.
knvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislvalvpa

subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 33-303 1.1e-71 234.6 In-house 26-294 (299) alignment
Range on Protein: 33-303
Range on HMM: 26-294/299.0
DSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVN
. .. .. .  |...   ..|.|. ||..| ||||||  |||.. .  | ||| ..|||||||||| . ||. . |.|.|| . .. ..||||||.  .|
eqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhecpain

TMYGFKEEMMRKRN-SHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHgdCEHGLIVDLIWSDPNRKDDTIQFNkMRGISTLF
 .||| ||  .. . . || .|.| || . ..  |. .|||||||.|||... | |  .|.|.     .  | .||.|.||..     . | .||.| .|
rvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdp..pnpslgidllwadpdqsvkdwlan.vrgvsyvf

GKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPN
|. || . . .| |||. |||.. . |. |  ...|.|.||||.| |   |  ..  . . |   .| ||| 
gqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkpt

subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 33-304 1.9e-61 201.0 In-house 25-296 (297) alignment
Range on Protein: 33-304
Range on HMM: 25-296/297.0
DSDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVN
.  .|..|    ....    ..|. ||. | ||||||. |||..    | ||  .|||||||||||  |.|  | |.. |. |  .. |||||||.  ||
eervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhecefvn

TMYGFKEEMMRKRN-SHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHGDCEHGLIVDLIWSDPNRKDDTIqFNKMRGISTLF
 .||| ||  .. .  ...  |.|||  | ..  |  ||||||||.|| .    .|  . |     . . .|. ||.|.||      . ... ||    |
kvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkierstegkerlvadllwadpisglsgf.menqrgagcgf

GKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPNK
|.  | .||. . .||. |||.. . |. |    .|.|.||||.| |.  |  .. .  . |.  .  |.|  
grdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeilrpts

PPP_1 34-287 8.3e-77 251.0 In-house 4-262 (264) alignment
Range on Protein: 34-287
Range on HMM: 4-262/264.0
SDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNT
. . |..|. ||.|.  . |.|. ... | ||||||. |||.. .  | .|. .||||||||||| .|.|. . |...|. . |...||||||| |.|..
eelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqvtk

MYGFKEEMM-RKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHgdCEHGLIVDL-------IWSDPNRKDDTIQfNKMR
.||||.|.. .| .....|.. |||. |...| |. |||..|||.||.... |.   ... ..    |.| . ||        .||......... | .|
vygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktev..peegklcdllekdvdillsddkeqeeava.nsiR

GISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVA
|.. ||||.|..... .  ..|||||||.||.|. | ......|.|||. |  . ||.|.. 
GagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayv

subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 34-301 8.1e-66 215.3 In-house 9-273 (280) alignment
Range on Protein: 34-301
Range on HMM: 9-273/280.0
SDILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNT
 .|. ... .. |.     |.|  ||. | |||| |  |. .. . .|| |. . .||||||||||. .|| . |||.|| .  ...|||||||   || 
heiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnk

MYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPrvHGDCEHGLIVDLIWSDPNRKDDTiQFNKMRGISTLFGK
.|||  |   |    ||  |. .|  . ... |....||||||.||..   |..  . .|      ..||..||.||||  | .   |  .|||| .|||
iygfyvecqykygvglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprp..cepldrgllidllwsdptnkgeg.wfhsirgisymfgk

SVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLK
 ||.. | .| ||||||||.. . |. .    ||.|||| | |  . .|  .|  .   |.. .  | 
gvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqli

subfamily_PPP7C_pd Subfamily PPP7C 35-181 1e-33 109.6 In-house 37-191 (383) alignment
Range on Protein: 35-181
Range on HMM: 37-191/383.0
DILEVLKTIKEILEPLPCLIEII----APVVVFGDIHGQLGDLLQFTNEVGRP-PDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVR
 .|..|.  |..|. || . ..       | | ||.||.| |||      | | ..  |.| ||.|||| .|.|. . |... ... |.|.| |||||  
yvllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedh

RVNTMYGFKEEMMRKR---NSHLWKVFNDVFAELSICASINRKILCMHGGISPKI
 .|  |||  |.. |    .... ....|||| | ... |..||| .||||| | 
ilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdkt

subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 36-310 4e-63 206.5 In-house 8-281 (284) alignment
Range on Protein: 36-310
Range on HMM: 8-281/284.0
ILEVLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNTMY
.  .|    .|..  | |||. .|. . ||||||. |||.. .. | |   .|||||||||||   ||  . ||. |..| ... .||||||.  .| .|
vetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiy

GFKEEMMRKRNS-HLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHGDCeHGLIVDLIWSDPNRKDDTIQFNkMRGISTLFGKS
|| ||  |. |   ... |. ||... . | . ..|||||||.|  ..    |  . .|    .    | .|..||||   .   . |  ||.| .||  
gfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpep.ntlaidilwsdptnfqkgwnpn.srgvsyvfgsd

VVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPNKGYDRSK
 . .|   | |||..|||.. . |. |  . ||.|.||||.| |.  |  .|  . | |   .| |.| |   | .
alrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlrprkkiarrr

subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 39-304 1.3e-58 191.6 In-house 28-293 (307) alignment
Range on Protein: 39-304
Range on HMM: 28-293/307.0
VLKTIKEILEPLPCLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNTMYGFK
|.   . |.    .|..|  |.|| ||.|||. ||...   .||||.  |.| |||||||  |||. . ||..|| ..... |||||||. |||  ||| 
viyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnkkygfy

EEMM---RKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPRvhGDCEHGLIVDLIWSDPNRKDDTIQfNKMRGISTLFGKSV
|| .    |    .| .|. .| .| | | |  ||||||||.|| .   | |    ||    .   |.. |..|.||.      .    ||    ||  |
eecvtsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpi..rnpfrgivndmlwadpdpsvfewk.assrgsgftfgtnv

VDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPNK
.|..|  | ..||||||.|   |.      .|.|.|||| |     | | |  . ..| ...|.. |. 
iddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgiqlvafvpes

subfamily_PPPLV_pd Subfamily PPPLV 52-302 1.6e-48 158.5 In-house 18-287 (290) alignment
Range on Protein: 52-302
Range on HMM: 18-287/290.0
CLIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPP-D---FQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNTMYGFKEEMMRKRNS
 |.|. .|. |.||.||.  ||  | . . |   |    ..||||||||||. |.|.  .|. .|.|.  ||.|||||||.. |   . .| | . |   
rllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvqesieykgegsfkfgd

H---LWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGM--TKPRVHGDCEH-GLIVDLIWSDPNRKDDT-----------IQFNKMRGISTL
.    |. ||.||  | . | |.||..|.|.||   | .   .. .     |.. | .   | .|..||||. . |              .|. || . .
sleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvlneGfvdndrrGtghv

FGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHnSNLGSVATISKSlKLRIVTLKP
|..  ....     .. ..||||.||||  .  . |||||||.  | |  ||  ..  ..|. ||||.|  |
fsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGs.sneaalilvdkk.klriittgp

subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 53-303 1.9e-71 233.8 In-house 2-256 (263) alignment
Range on Protein: 53-303
Range on HMM: 2-256/263.0
LIEIIAPVVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNTMYGFKEEMMRKRN-----S
|.|. ||. . || |||  |||.  | .|     ||||||||||||  |||| . || .|. . .|.||||||||.. .|  |||. |. .. .      
llelqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevye

HLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLTGMTKPrVHGDCEHGLIVDLIWSDPNRKDDTIQFNKMRGISTLFGKSVVDNLCTTLAIDL
 ... ||.||. . .|| ....||||||||||...| | .  .  | .     | | .||.|.||..    .. ||.| || .|||  ||.||  | |||
svynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplp.letakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidl

IIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVTLKPN
|.|||.. | |..|  | ||.|||||  |     |  .|  . | |.| .| |||.
ivrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkpe

Metallophos Calcineurin-like phosphoesterase 59-255 5.7e-39 127.4 Pfam-A 2-199 (200) alignment
Range on Protein: 59-255
Range on HMM: 2-199/200.0
PVVVFGDIHGQLGDL----LQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWL--FCMKILFSKKVHLLRGNHEVRRVNTMYGFKEEMM----------
...|.||.||.| ||    |.. .  ....   .|||||.||||..|.|.   |  .. |.|....|.|||||||.. .|. |||..|.           
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange

------------------------RKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDSLtgmtkprvhgdcehglivdliwsdpnrkddt
                         ... . .  ....|..|...| .. |||..||..|.  .|.|                                 
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................

iqfnkmrgISTLFGKSVVDNLCTTLAIDLIIRAHEMK
         |.|||. ....|.    .||..|.|. |
........gselfgpdalekllekygvdlvlrGHtHk

PPP_2 60-255 3.3e-68 222.3 In-house 1-198 (198) alignment
Range on Protein: 60-255
Range on HMM: 1-198/198.0
VVVFGDIHGQLGDLLQFTNEVGRPPDFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNTMYGFKEEMM-RKRNSHLWKVFNDVFA
|.|.||.|||| |||..... ...|. .||||||||||| .|||| ..|...|. . |.||||||||| ..||..||||.|.. .| .....| ...||.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe

ELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHgdCEHGLIVDLI----WSDPNRKDDTIQfNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEM
 |...| |..|.|..|||.|..|...|. . .......  .|.|...||     .|||..|..... |. ||...|||..|...|...  ..|||||||.
lLplaalidekvlvvHGGlseeiklldqikkeerkies..peegklldlleeeklsdpkekeella.nsarGagllfgpdvteelleknklkliiRaHev

K
|
k

PPP_4 60-255 3.4e-66 216.0 In-house 1-197 (197) alignment
Range on Protein: 60-255
Range on HMM: 1-197/197.0
VVVFGDIHGQLGDL-LQFTNEVGRPP-DFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNTMYGFKEEMMRKRNSHLWKVFNDVF
|.|.||||||| || |....  |.|. . .|.|||||||||..|||| ..|...|. . |.|.||||||| . .| .||||.|...|......| ..|||
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlekhgkeilkklqdvf

AELSICASINRKILCMHGGISPKIESWDSLTGMTKPRVHgDCEHGLIVDL-IWSDPNRKDDTiQFNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMK
. |...| |..|.|..|||.|...||.|..  ......  ..|.... || .||||......   |. ||...|||..|.......  ..||||.||.|
dllplaalidekvlvvhgglsdelesldkierierkies.pleeekrkdlllwsdpreaqeg.lansvrGagllFgpdvtekfleknnlkliirshelk

PPP_5_Dcr2 60-255 2.3e-63 206.8 In-house 1-199 (199) alignment
Range on Protein: 60-255
Range on HMM: 1-199/199.0
VVVFGDIHGQLGDL-LQFTNEVGRPP-DFQYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNTMYGFKEEMMRK-RNSHLWKVFNDV
|.|.||.||||.|| |.. .|.|.|. . .|.|||||||||..||||...|...|... |.||||||||| . .| .|||..|...|  .....|...||
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv

FAELSICASINRKILCMHGGISPKIESWDSLTGMTKPrVHGDCEHGLIVDLI-WSDPNRKDDTIQFNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMK
| .|...| |..|.|..|||.||.|.|...|  .... ..   |.|   ||. ||||... .... |. ||...|||..|.......  ..||||.||.|
fdwlPlaalidekvlvvhgglspeiksiellekierk.ieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshelk





subfamily_YNL217W_pd Subfamily YNL217W 60-145 2e-08 27.0 In-house 12-99 (235) alignment
Range on Protein: 60-145
Range on HMM: 12-99/235.0
VVVFGDIHGQLGDLLQFTN--EVGRPPDFQYLFLGDYVDRGPNSLEVTVWLfcmkilFSKKVHLLRGNHEVRRVN------TMYGFKEEMMRKR
..| ||.||   .|... .  ..|. ..   ...|| ...||.|.||  ..       ...|. ..||||   .          |...  . ..
llvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvllaykwvkkpkgaeplefssk

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 87-303 2.6e-66 217.0 In-house 102-315 (317) alignment
Range on Protein: 87-303
Range on HMM: 102-315/317.0
QYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDS
.|||||||||||| |.|| . ||..|.|. .||.||||||| | ||| ||| .|. .. ...|...|. .|  | .|| .| |||||||||| .. . . 
kylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlkq

LTGMTKPRVHGDCehGLIVDLIWSDPNRKDDTIQfNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSV
|  . .|    |   |.. || |.||. . .. . .  || ...||.. |.... .| .||..|||.. | |. |  | .|.|.|||| | |.. |...|
ldklkrpldipdv..Gvladltwadpdaevkgyk.esarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaav

ATISKSLKLRIVTLKPN
 .. | ||. | .|.|.
lsvdkklkisinvlrpe

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 87-303 1.2e-53 175.4 In-house 121-334 (339) alignment
Range on Protein: 87-303
Range on HMM: 121-334/339.0
QYLFLGDYVDRGPNSLEVTVWLFCMKILFSKKVHLLRGNHEVRRVNTMYGFKEEMMRKRNSHLWKVFNDVFAELSICASINRKILCMHGGISPKIESWDS
.|||||||||||| |.|| . | ..|. .  ...||||||| | ||| |||  |.  . ...|...|...|  . .|| ||  |.||||||| .. |.. 
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyrydaqlyecfqnmfnvfpfcavinntimcmhggisehltsfnq

LTGMTKPRVHGDCehGLIVDLIWSDPNRKDDTIQfNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSV
.. . .|    |   |.. || |.||.  .   .    || | .||   .  .   | ....|| |.. | |. |    ||.|.|||| | |.| |  .|
fsvfkrpleipdv..gvltdltwadpdptekgyk.psargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaav

ATISKSLKLRIVTLKPN
 .| | ||. |  ..|.
fsidkklkisinvfrpe

Chitin_synth_1 Chitin synthase 105-155 9.6e-06 11.9 Pfam-A 83-132 (163) alignment
Range on Protein: 105-155
Range on HMM: 83-132/163.0
TVWLFCMKILFSKKVHLLRGNHEVRRVNTMYGFKEEMMRKRNSHLWkVFND
 .. .  ..  ... .. . ....  |  .. .||.  .| |||.| .|| 
hiyeyttqlsidenlkfkgkekglvPvqllfclkeknqkkinshrW.lfna

subfamily_PPP7C_pd Subfamily PPP7C 200-314 3.3e-21 68.5 In-house 233-346 (383) alignment
Range on Protein: 200-314
Range on HMM: 233-346/383.0
EHGLIVDLIWSDPNRKDdTIQFNKMRGISTLFGKSVVDNLCTTLAIDLIIRAHEMKEKGHTFEFDNRLLTVFSAPYYSGHNSNLGSVATISKSLKLRIVT
|   ..|..||||. |.   . | .||  . ||  | ..| .   ..|.||.|| | .|. |  |...||.|||  |  . || |.   ..|.|. ||| 
ewrqvldilwsdpkake.GckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltprivq

LKPNKGYDRSKLDKR
 . .|   .. | .|
yqaskatkkltlrqr