Synonym: CELE_C52E4.7, C52E4.7
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Cele-STS-like_pd | Subfamily Cele-STS-like | 33-227 | 4.3e-81 | 262.6 | In-house | 1-210 (229) | alignment | ||
Range on Protein: 33-227
Range on HMM: 1-210/229.0
EIIVMRCAETINEIFSDWTKRANLdENKYTPFDVNAPIELPRRTdmlKSYNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYI
|..|.|.||...|.|..|.|.|.| |.||.|.|.|.|.|||.|. |||.||||..|.||||||.|.|.|.||...|||.|||||..||.||.|.....
evvvirsaervdevfgkWiksadl.etkyrpldinvPkelpkra...ksykldpPlteiGkiaskligRaLrdrgiepsvvFCSPdlrsvqtaalllkgl
GEKCGAIRIEPELSTLHKSAHVFFGPNHFTSLGYGIDEK-NPLHAVSDGVSLSDLVNRIKRAFYELTSKVDNALIIV------------------DSLSM
|.|..||..||.|....|...|...|..|..|||..||| .||...|...||||.|.||..||..|.|||...||.| |.|..
GlkraaisvePgLleyrkarevllppkafkklgypvdekYkPlkelsmaeslsdfvariqaafkkllskveqklilvvadnvsleltrredvesvddllv
MIISSLFHNVYIRN
.........|.|.|
llkktpalsvvivn
|
|||||||||
subfamily_STS_pd | Subfamily STS | 33-238 | 2.3e-59 | 192.8 | In-house | 2-213 (245) | alignment | ||
Range on Protein: 33-238
Range on HMM: 2-213/245.0
EIIVMRCAETINEIFSDWTKrANLdENKYTPFDVNAPIELPRRTDMLKSYNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYI
.|...|..|...|.|..|.| .. |.||...|.|.| |||||.|.||.|. |||..|.|.|..|...|.|..... ...|||||.. ...||. | ...
tiyivRhgeRvdevfgkWlk.sfd.egkyerkdlnlpkelprrpdglkdyksDpPlterGviqAkllgraLleagikiehifcSPslrciqTaaailkgl
GeKCGAIRIEPELSTLHKSAH----VFFGPNHFTSLGYGIDEKN-PLHAVSD---GVSLSDLVNRIKRAFYELTSKV--DNALIIVDSLSMMIISSLFHN
| |. .|..||.| . .|... ....|.........|||.. |....|. . | ..|..|||....|...|| |....||.. ......| ..
g.kkikikvepgllewlkldrkpipellspeelkkffpqidedYkpvlslselkskeseeelyeRikkvvkeiiekvpedgniliVahaatldalsrqll
VYIrNDSSVDLERLRS
. ...|.||..|
gls.presedlkklvi
|
|||||||||
0048955 | Phosphoglycerate mutase-like | 33-223 | 4.8e-15 | 48.6 | In-house | 2-195 (240) | alignment | ||
Range on Protein: 33-223
Range on HMM: 2-195/240.0
EIIVMRCAETINEIFSDWTKranldenkytpfdvnapielprrtdmlksyNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYI
.....| .|. . ... |.|..|.|. ...... | |.. ......|| ...||..| ...
rlyLvRHGesewnaegrlqg..............................wtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaeal
GEKCGAIRIEPELSTLH----------------KSAHVFFGPNHFTSLGYGIDEKNPLHAV-------------SDGVSLSDLVNRIKRAFYELTS----
| .. ....|.| .. . . | . .... . .... ..|. . .| || |...|...|. || .
glpllpvvvdprlrErdfgalegltldeiaekfpeelvlwlrdpldvrppllelldellllldlryalldedllpggEsladvaaRvlaaleellaralk
KVDNALIIVDSLSMMIISSLFHNV
. .| |.. . ... . . ....
pgknvlvVsHggvirallayllgl
|
|||||||||
0051064 | Phosphoglycerate mutase-like | 34-222 | 9.6e-15 | 47.7 | In-house | 6-197 (241) | alignment | ||
Range on Protein: 34-222
Range on HMM: 6-197/241.0
IIVMRCAETINEIFSDWTKranldenkytpfdvnapielprrtdmlksyNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYIG
....| .|. .. |.|..|.|. ...... | |.. ......|| ...||..| ...|
lyLvRHGesewnaegrlqg..............................wtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaealg
EKCGAIRIEPELSTLH----------------KSAHVFFGPNHFTSLGYGIDEKNPLHAV-------------SDGVSLSDLVNRIKRAFYELTSK----
.. ....|.| .. . ..|.. .... . .... ..|... .| || |...|...|. || ..
lpllpvvvdprlrEidfgalegltleeiaekfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellarllld
VDNALIIVDSLSMMIISSLFHN
.| |.. . ..... . ...
gknvlvVsHggvirallayllg
|
|||||||||
His_Phos_1 | Histidine phosphatase superfamily (branch 1) | 34-207 | 7.1e-09 | 28.8 | Pfam-A | 2-149 (158) | alignment | ||
Range on Protein: 34-207
Range on HMM: 2-149/158.0
IIVMRCAETIneifsdwtkrA----NldenkytpfdvnapielprrtdmlKSYNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIK
....| .|. . . . |.|..|.|. . ....|.. . ......|| ...||...
lylvRHGese..........wnkegr........................lqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeill
SYIGekcGAIRIEPELSTLHKS----AHVFFGPNHFTSLGYGIDEKNPLHAVSDGVSLSDLVNRIKRAFYELT---SKVDNALII
.. |..||.| .. . ...| . ..... .. .| || |...|..... || .| .| ||.
eeld...ipiikeprLrerdfgeweglpkeevkeefpeeyekwkrdkkefrppegesladvyeRvapfleelieakdkgenvliv
|
|||||||||
His_Phos_1 | Histidine phosphatase superfamily (branch 1) | 34-207 | 7.1e-09 | 28.8 | In-house | 2-149 (158) | alignment | ||
Range on Protein: 34-207
Range on HMM: 2-149/158.0
IIVMRCAETIneifsdwtkrA----NldenkytpfdvnapielprrtdmlKSYNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIK
....| .|. . . . |.|..|.|. . ....|.. . ......|| ...||...
lylvRHGese..........wnkegr........................lqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeill
SYIGekcGAIRIEPELSTLHKS----AHVFFGPNHFTSLGYGIDEKNPLHAVSDGVSLSDLVNRIKRAFYELT---SKVDNALII
.. |..||.| .. . ...| . ..... .. .| || |...|..... || .| .| ||.
eeld...ipiikeprLrerdfgeweglpkeevkeefpeeyekwkrdkkefrppegesladvyeRvapfleelieakdkgenvliv
|
|||||||||
0035570 | Phosphoglycerate mutase-like | 81-233 | 2.8e-13 | 42.4 | In-house | 20-173 (219) | alignment | ||
Range on Protein: 81-233
Range on HMM: 20-173/219.0
SynlDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIksyigeKCGaIRIEPELSTLHKSA----HVFFGPNHFTSLGYGIDEKNPLHA
. |.|..|.|. ...... | |.. . ....|| ...||..| .. ..|.|.| .. . .. ... . . . . . ..
g...dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii......glp.veidprLrEidfgdlegltldeiaekypeelaawlrdpydyr
VSDGVSLSDLVNRIKRAFYELtSKVDNALIIVDSLSMMIISSLFHN--------VYIRNDSSVDL
..| || |.|.|...|. || . .| |.. .. .. .. ... . . . |.| . |
ppggEsladvvaRvlpaleel.edgenvlvVsHggvirallayllglpleeilrlnlpngsvtvl
|
|||||||||
0039931 | Phosphoglycerate mutase-like | 81-229 | 5.4e-11 | 34.8 | In-house | 20-169 (219) | alignment | ||
Range on Protein: 81-229
Range on HMM: 20-169/219.0
SynlDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIksyigeKCGaIRIEPELSTLHKSA--------HVFFG---------------
. |.|..|.|. .. ... | |.. . ....|| ...||..| .. ..|.|.| .. . .
g...dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii......glp.veidprLrEidfgdlegltleeiaekypeelaawlrdpydyr
PnhftslgygideknplhavSDGVSLSDLVNRIKRAFYELTSkVDNALIIVDSLSMMIISSLFHN--------VYIRNDS
| ..| || |.|.|. .|. || . .| |.. .. .. .. ... . ... | |
p...................pggEsladvvaRvlpaleella.genvlvVsHggvirallayllglsleeilrlnlpngs
|
|||||||||
0037864 | Phosphoglycerate mutase-like | 83-223 | 5.1e-11 | 34.9 | In-house | 29-177 (211) | alignment | ||
Range on Protein: 83-223
Range on HMM: 29-177/211.0
NLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYIGEKCGAIRIEPELSTLHKSA----HVFFGPNHFTSLGYGIDEKNPLHAVS
||.|..|.|. ..... | |.. ......|| ...||..| ...| ....|.| .. | .. ... . . . .. .
wldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiilealglpllpvevdprlrErdfgalegltleeiaekypeelvawlrdpydfrpp
DGVSLSDLVNRIKRAFYELTSKV----DNALIIVDSLSMMIISSLFHNV
.| || |.|.|...|. || . .| |.. .. .. .. ... ..
ggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllgl
|
|||||||||
0053607 | Phosphoglycerate mutase-like | 83-223 | 5.7e-10 | 31.6 | In-house | 22-157 (191) | alignment | ||
Range on Protein: 83-223
Range on HMM: 22-157/191.0
NlDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIksyigekCGAIRIEPELSTLHKS------------------AHVFFGPNHFTSl
|.|..|.|. . .|. | ... . ....|| ...||..| ....|.| .. |. . .| ...
g.dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii.......glpvevdprlrEidfgdwegltleelaekypeelaawlrdpldyrp.
gygideknplhavSDGVSLSDLVNRIKRAFYELTSkVDNALIIVDSLSMMIISSLFHNV
..| || |...|. .|. || . .|.|.. .. ..... ... ..
.............pggEsladvaaRvlpaleella.ggnvlvVaHggvirallayllgl
|
|||||||||
0043909 | Phosphoglycerate mutase-like | 84-223 | 2.7e-11 | 35.9 | In-house | 25-201 (249) | alignment | ||
Range on Protein: 84-223
Range on HMM: 25-201/249.0
LDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYIGEKCGAIRIEPELSTL----------------HKSAHVFFGP---------
||.|..|.|. ..... | ... ......|| ...||..| ...| ....|.| . . ..|..
lDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileelgldklpvevdprLrErdfGalegltkaeiaekypeelvawlrrsydvlppl
---NHFTSLGYGIDE-----KNPLHAVSDGVSLSDLVNRIKRAFYELTSK----VDNALIIVDSLSMMIISSLFHNV
.. . | . .| .|. . .| || |.|.|...|. || . .| ||. . .. .. ......
leeldelllellldyaladldplldrppggEsladvvaRvlpaleellarllkdggnvliVaHggvlrallayllgl
|
|||||||||
0049178 | Phosphoglycerate mutase-like | 84-223 | 5.6e-11 | 35.1 | In-house | 26-196 (243) | alignment | ||
Range on Protein: 84-223
Range on HMM: 26-196/243.0
LDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYIGEKCGAIRIEPELSTLH----------------KS-------AHVFFGPNH
.|.| .|.|. . ... | ... . ....|| ..||..| ...| .. ....|.| .. .. | .
tDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiilealglpllpvvvdprLrErdfGalegltkaeiaakypeelvawwrdpydarppa
FTSLGYGIDEKNPL----HAVSDGVSLSDLVNRIKRAFYELTSK----VDNALIIVDSLSMMIISSLFHNV
.. |...... .| . . .| || |...|...|. || . .. |.. . ..... .|. ..
lllldlllplldrlladldllpggEsladvaaRvlpaleellaellhdgktvlvVaHggvirallalllgl
|
|||||||||
0036777 | Phosphoglycerate mutase-like | 84-222 | 6.1e-11 | 34.9 | In-house | 25-196 (247) | alignment | ||
Range on Protein: 84-222
Range on HMM: 25-196/247.0
LDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYIGEKCGAIRIEPELSTL-----------------------HKSAHVFFGP--
||.|..|.|. | ... | ... . ....|| ...||..| ...| ....|.| . . .... |
lDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGalegltkaeiaekypeelvawwrdpydyrppl
----NHFTSLGYGIDEKNPLHAVSDGVSLSDLVNRIKRAFYELTSK----VDNALIIVDSLSMMIISSLFHN
. | . .. ||. . .| || |.|.|...|. || . .| |.. . .. .. ... .
lelllelllldllryallpldllpggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllg
|
|||||||||
0036887 | Phosphoglycerate mutase-like | 84-224 | 6.1e-10 | 31.6 | In-house | 24-165 (202) | alignment | ||
Range on Protein: 84-224
Range on HMM: 24-165/202.0
LDPPINETGKIASKMIARELCdrHAIPSVIFCSPDFASVETAHLIKSYIGekcGAIRIEPELSTLHKSAHVFF----GPNHFTSLGYGIDEKNPLHAVSD
||.|..|.|. ..... | . . ....|| ...||..| ...| ....| | .. .| ... . . . . .....
ldvpLtelGreqaralgerla..glpfdavysSpllRaiqTaeiiaealg...lpvivdprlrEidfgalegltleeiaekypeelaawlrdpydfrppg
GVSLSDLVNRIKRAFYELTSKV--DNALIIVDSLSMMIISSLFHNVY
| || |.|.|. .|. || .. .| |.. .. .. .. ... ..
gEsladvvaRvlaaleellarldggnvlvVsHggvlrallayllgls
|
|||||||||
0050036 | Phosphoglycerate mutase-like | 84-223 | 6.9e-08 | 24.6 | In-house | 23-147 (171) | alignment | ||
Range on Protein: 84-223
Range on HMM: 23-147/171.0
LDPPINETGKIASKMIARELcdrhaIPSVIFCSPDFASVETAHLIKsyigekcGAIRIEPELSTLHKSAHVFFGP--------NhftslgygIDEKNPLH
.|.|..|.|. . ... | . ....|| ...||.|| ....|.| .. | . .. . .
tdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil.......lpvivdprLrErdfGawegltldeiaakype........wlldlldl
AVSDGVSLSDLVNRIKRAFYELTskvDNALIIVDSLSMMIISSLFHNV
|. .| || |...|. .|. ||. .| |.. . ..... .|....
appggEsladvlaRvlpaleell...gnvlvvaHggvirallalllgl
|