Gene F20D6.6 in Caenorhabditis elegans

Synonym: CELE_F20D6.6, F20D6.6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP063_AA protein Get Run
CeleP063_AA_13-305 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPP5C_pd Subfamily PPP5C 12-301 1.9e-29 95.7 In-house 18-309 (322) alignment 
Range on Protein: 12-301
Range on HMM: 18-309/322.0
RNFYEEIIQIHLQKGPVEHEYSFGFLSELLeDALEIMDGTSRVEY-ITPPVNICGDIRSRYGDVLDIFKTCGWPFE-QKYVFLGNLIDGGKFSLETLVIL
..| .|... . ..  ... |..  |.|   . |. .     ..   |  . .|||| ... |.|.||.  | | | . |.| |...| | ||.|....|
kefvkellelfkkqkklhkkyalkilleak.ellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltl

LCCKICYPQNFVILRGFYEHELVKSDRSFIGELRVRFPdsnkwQALNAIIKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNE-KNVVSVKNGNMFENHNTR
|. |. ||..| . || .| . .     | || . ..      ...  . . . . ||. .|.| |.| | | . |. .   ...  ..  .   .... 
lgfkllyPnhfflsrGnhesdnmnklyGfegevkakyt.....ekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegll

VEVQFLDIDIPSPVTPNK----IDEESKIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMM-DRHNKVNFKSIQGI
||. . | .  . ..| |    .     . |..||. .....| | .| .|||... . .|||. |      . .|.| .. . . ..|..||. . .
vellwsdpqeanGrspskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfeav
0049330 Metallo-dependent phosphatases 14-299 4.8e-44 143.9 In-house 12-297 (309) alignment 
Range on Protein: 14-299
Range on HMM: 12-297/309.0
FYEEIIQIHLQKGPVEHEYSFGFLSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCK
.. ..... ...   .. .|. .| .||. | ||.   . .  .. .. ..|||   . | | ... .|.| |...||||.|.| | .|||.| .||..|
lilslldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalk

ICYPQNFVILRGFYEHELVKSDRSFIGELRVRFPdSNKWQALNaiikSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQF
..||.|...||| .|  |.  ...| .|.  ..  .. |....     .|..||.. |.. |.||| | . ......... ....  .. .... ..  .
llypdnvfllrGNHElrllnglygfgdetlrkyg.aelweefl....dwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllw

LDID-IPSPVTPNKI----DEESKIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKSIQ
 | . | .  .||.          .....||  .....| ....| .||..  ...|||. | ..  ....|.| |...| . ...|. ..
sdplpiregfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfe
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 22-297 2.5e-31 101.8 In-house 6-285 (290) alignment 
Range on Protein: 22-297
Range on HMM: 6-285/290.0
HLQKGPVEHEYSFGFLSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFV
||.|  | . .|   . |.|| . ||..    .  .  |. | |||  . ...|  |.  | | . |..|||. .| |  |||  ..|.| || |...  
hllkygvldafsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvh

ILRGFYEHELVKSDRSFIGELrVRFPDSNKWQALNAIikslLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDIDIPS-
.||| .|   |.    |  || .|  .|. |.  . .    .. |.. . ..||.||. | .. .|.  . . ..|  ..  . .  . |..|  |    
llrgnhevrkvnrlygfkeel.arkrgsrlwkqyqdv....faelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrd

---PVTPNKIDEES-----KIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKS
    .. ||    |     | . .||| . .|... . .| .||. | ....|.|. |      |  | | .. .    ....  
kddtialnkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivv
subfamily_PPP3C_pd Subfamily PPP3C 25-196 2.4e-29 95.4 In-house 38-200 (452) alignment 
Range on Protein: 25-196
Range on HMM: 38-200/452.0
KGPVEHEYSfgflSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILR
.| .|.|       ...|.| ...   . .  .  |. ..|||  .. |.|..|.  | | ..||.|||. .| | ||.|... |...||.||... .||
egrleeeaa....lkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllr

GFYEHELVKSDRSFIGELRVRFPDsnkwQALNAIIKSlLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSV
| .|   . .  .|  |.....      .  .|...| .. ||. ..||.. ||| | ....||. ... ..
Gnhecrhlteyftfkeeckikyse....evydacmes.fdslPlaallnqqflcvhGGlspeikslddikkl
0053225 Metallo-dependent phosphatases 29-297 3.4e-41 134.7 In-house 19-287 (293) alignment 
Range on Protein: 29-297
Range on HMM: 19-287/293.0
EHEYSFGFLSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYE
   .|. .| .||. | ||.   . .  .. .. ..|||   . | | ... .|.| | ..||||.|.| | .|||.| .||..|..||.|.|.||| .|
lkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkllypdnvvllrGNHE

HELVKSDRSFIGELRVRFPDSNKWQALnaiiKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDIDIPSPVTPNK--
  |.  ...| .|   .. ... |..|      .|. ||.. ... |.|.| | .  .. ..... ...   .......  .  . | |. |. .|..  
lmllnglygfgdetlrkygaaelwdel....ldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpdlwsgwlpsyrg

--IDEESKIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKS
  .     .....||  .. ..|....|| .||..  ...|.|. | ..  . ..|.| |...| . ...|| 
lgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfkl
subfamily_PPP7C_pd Subfamily PPP7C 30-186 1.7e-22 72.7 In-house 35-190 (383) alignment 
Range on Protein: 30-186
Range on HMM: 35-190/383.0
HEYSFGFLSELlEDALEIMDGTSRVE-YITPPVNICGDIRSRYGDVLDIFKTCGWPFE-QKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFY
 .|    | |  .. |. .   |||.  |.  | .|||.  .  |.| |.   | | | . ||| |...| || |.| |.|||.  . ||... . || .
akyvllilrea.kkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnh

EHELVKSDRSFIGELRVRFPDSNKwqALNAIIKSLLKRLPVMTVLNRKLLCVNGMVTSN
|  ..     || |.  .... .|   . .... . . ||. |....|.| | | .. .
edhilnlryGfikeveskykvhgk..kilrlledvfawlplatlidekilivhGGisdk
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 31-198 3.9e-21 68.5 In-house 5-182 (302) alignment 
Range on Protein: 31-198
Range on HMM: 5-182/302.0
EYSFGFLSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKT----------CGWPF-EQKYVFLGNLIDGGKFSLETLVILLCCKICYPQN
|||   |  |.|   | .   . .  |.||| | |||  .. |.. |...            . | ..|.||||. .| |. |.| . .... |..||.|
eysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptn

FVILRGFYEHELVKSDRSFIGELRVRFPDSNKWQaLNAIIKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKN
...||| .| . .    .| .||  |.  ..  . .    .  .  .|. ... .|.||| | .. ...  ... ..|.
yillrgnhetkainfaygfreelenrlgkkdgke.iwekfnevfsfmplaalvgekilcvhggispklesledikkikr
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 31-198 4.4e-21 68.3 In-house 6-183 (302) alignment 
Range on Protein: 31-198
Range on HMM: 6-183/302.0
EYSFGFLSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKT----------CGWPF-EQKYVFLGNLIDGGKFSLETLVILLCCKICYPQN
|||   |  |.|   | .   . .  |.||| | |||  .. |.. |...            . | ..|.||||. .| |. |.| . .... |..||.|
eysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptn

FVILRGFYEHELVKSDRSFIGELRVRFPDSNKWQaLNAIIKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKN
...||| .| . .    .| .||  |.  ..  . .    .  .  .|. ... .|.||| | .. ...  ... ..|.
yillrgnhetkainfaygfreelenrlgkkdgke.iwekfnevfsfmplaalvgekilcvhggispklesledikkikr
0045823 Metallo-dependent phosphatases 32-305 7.7e-46 149.8 In-house 43-328 (473) alignment 
Range on Protein: 32-305
Range on HMM: 43-328/473.0
YSFGFLSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHEL
... .| .||..| ||.   . .  ..... ..|||   . | | ... .|.| |...||||.|.| | .|||.| .||. ||.||.|...|||  |. |
lpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkikypgnvfllrGNHElrl

VKSDRSFIGELRVRFpDSNKWQALNAIikslLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENhntrvEVQFLDIDIPSPvTPNKIDE--
.  .. | .|.. .. . . ......     |..||.. |.. |.|.| | . ....... .....  .....     . ..||.    | .. . |.  
lnglygfgdetleky.gedlyeeflew....lrslPlaaviggkilfvHGGlspdlplldqireierpleipd.....dgllldllwsdP.weddgdgll

----------------ESKIIKELLKSMDMSMMINSNNVVREGYRFTLKNQ------LITITSGTKLQKNYNNRGVVMMMDRHNkVNFKSIQGIDGED
                  ....|.|| ... ... .  .|.|||... ...      .||. | .    ...|.. |...| .  ..|. .. .. . 
rlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsphpl
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 32-185 2.7e-21 69.1 In-house 20-171 (307) alignment 
Range on Protein: 32-185
Range on HMM: 20-171/307.0
YSFGFLSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHEL
|.   . ... .|  |.     .  | ||. . ||.  .. |....|   | | |  ||| |. .| | .|||....|.. |||||.| |.||| .|   
ytkeefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiar

VKSDRSFIGELRVRFPDSNkwQALNAIIKSLLKRLPVMTVLNRKLLCVNGMVTS
|.   .|  |     |     . . |...  .. ||. ...  |.||. | .. 
vnkkygfyeecvtsipkcg..eeiwalfqrcfnnlpisaliatkilcmhgglsp
subfamily_PPP1C_pd Subfamily PPP1C 37-299 2.7e-47 154.3 In-house 15-277 (282) alignment 
Range on Protein: 37-299
Range on HMM: 15-277/282.0
LSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDR
...||. | ||.  .. .  .. ||.|.|||  .| |.| .|.|.| | |..|.|||. .| ||.||||.|.||. || ||.|. .||| .|   ..   
ieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesasinriy

SFIGELRVRFPDSnKWQALNAIikslLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDIDIPSP-VTPN----KIDEES
 |  | . |.     |.... .     . ||. .... |.||| | .....|. ... ...     ...   ... . | |  .  .. |    ..  ..
Gfydeckrrysik.lWktftdv....fnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsftfgk

KIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKSIQ
......|...|..... . .||..||.|  |.||.|. | ..   ...| |.|. .|.. .|.|. ..
dvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilk
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 37-297 4.4e-45 147.0 In-house 29-290 (298) alignment 
Range on Protein: 37-297
Range on HMM: 29-290/298.0
LSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDR
...|.| | .|.   . .  . .|...||||  .| |.| .|. .|.| .. |.|||. .| |...||..|.||. |. ||.||..||| .| |..    
veklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnffllrGnheceainrvy

SFIGELRVRFPDSNKWQALNaiikSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGnmFENHNTRVEVQFLDIDIPS---PVTPNKID----E
 |  | . |. . . .....     ... ||.....  ..||. | .. ..|. ... ..|    |......... .|  |  .     ..|.       
Gfyeeckrrykslrlyaefq....dvfnalpltaliggrilcmhGGlskklksldqlrelkrp..fdskeeslaidllwadpenavkgwaensrGvsvvf

ESKIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKS
 .. .|.||...|. ... . .||..|| |  ...|.|| |  .  ....|   ||..| . .| |. 
GedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfev
PPP_3 37-299 2.3e-43 141.2 In-house 7-270 (271) alignment 
Range on Protein: 37-299
Range on HMM: 7-270/271.0
LSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDR
| ||.. . ||.  .| .  |. ||..||||  .. |.| .||..| . |.||.|||. .| ||.|||.|..||..|| ||.....|||  |.. . .  
lkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrqinkvY

SFIGELRVRFPDSNKWQALNAIikslLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDIDIPSPVTPNKIDEE-----S
 |  |.  .  ... ...|. .     . ||. .....|.|.| | . ..||..... . .. .  ... . .. .. . .    .. |.         .
gFkkevlkkkggkkvykklqev....FelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFgp

KIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKSIQ
.. .|.|........| . ... |||... .....|. | ... ....|.| .. ...... .|| ..
dvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkqle
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 37-306 1.6e-39 128.5 In-house 15-287 (287) alignment 
Range on Protein: 37-306
Range on HMM: 15-287/287.0
LSELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDR
. |.|| . ||..  . .  .. |..|.|||  ...|.| ||. .| . . .|.|||. .| |  |||  ..|.. || ||..  .||| .| . .    
ilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevkkinkly

SFIGELRVRFPdSNKWQALNAIikslLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDIDI---PSPVTPNKIDEESKI
 |  ||. ..  .. ..  | .    .. ||. . .....||. | .. ..|  ... ..|  ..  . .  . |..|  |       . .|||   |..
Gfkeelkrkrq.erlykqfndv....fselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvv

-----IKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKSIQGIDGEDR
     . .||| .|..... . .|..||| | ....|.|. | .. . .  | | |.....  ...|  ..  |.|.|
fGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpedfevr
PP2Ac_SM00156 38-298 4.9e-46 149.9 In-house 7-267 (271) alignment 
Range on Protein: 38-298
Range on HMM: 7-267/271.0
SELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRS
 ||||.. ||..  . .  ...|| ..|||   . |.| .... | | |.||||||. .| |..|.|....|.. ||.||...|.|||  | . |   . 
lelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssvnkiyg

FIGELRVRFpDSNKWQalnaIIKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDI-DIPSPVTPNKiDEESK----
|  |.. .  ... ..    ..... . ||. .....|.||..| . ..... ... ..|  .  ..... ... . |  .  . ..|.|    |     
feeevkrky.gkeiye....kfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpsk.rglsvvFge

-IIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKSI
 ..||.||...... | . .|| |||.|  ...|.|| | .. .....| ..|. .. . | .....
davkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieql
PPP_1 38-286 6.9e-40 130.0 In-house 7-263 (264) alignment 
Range on Protein: 38-286
Range on HMM: 7-263/264.0
SELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRS
 ||.. . |..  .. .  .. .. .||||  .. |.| .||..| . |..|.|||  .| ||.|.|.|..||. |. ||... .|||  | . | .  .
aelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqvtkvyg

FIGELRVRFPDSNKWQALNAIikslLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEV--QFLDIDIPSPVTPNKIDEE-----
|  |.. .  ... ...|  .     . ||. .... |.|.| | ...... ....  ... .   .. .  .   .  ||.. .. . ..  ..     
FkkEvlkkkyskeiyktltdv....FdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRGa

-----SKIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMM
     .......|.. .....| . .|..|||.|. |....|| | . . .. .|||... 
gylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvk
subfamily_PPP2C_pd Subfamily PPP2C 38-297 9.6e-30 96.8 In-house 23-282 (290) alignment 
Range on Protein: 38-297
Range on HMM: 23-282/290.0
SELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRS
 || | | ||.   | |. .  || .|||.  .. |.|..||  |   . .|.|||. .| | .|.||. .| . |. |..  .|||| .|   .     
kelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqitqvyg

FIGELRVRFPDSNKWQALNaiikSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDIDIPSPVTPN----KIDEESKI
| .|   .. ..| |. .      |.  ||. ........|. | .. .|.   .. ...  .   .  . ... . | |  .  .            .|
fydeclrkygnanvwkyft....dlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpddrggwgisprgagytfgkdi

IKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKS
 ... |. ...... . ..| |||... .....|| |  .      |.. .. .| . | .|  
sekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflq
subfamily_PPP6C_pd Subfamily PPP6C 39-305 1.5e-34 112.4 In-house 22-288 (290) alignment 
Range on Protein: 39-305
Range on HMM: 22-288/290.0
ELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSF
.| .  |...   | |. .. || .||||  .. |....|.| |   ...|||||. .| | .||||.  ||. |. ||.. ..||| .|   .     |
klcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqitqvygf

IGELRVRFPDSNKWQALNAIikslLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDID-IPSPVTPNK---IDEESKII
  |   .. ..| |. .  .    .  |.. .... ..||| | .....|  ...  ..  .   .. . ... . | . . . .. ..       ||. 
ydeclnkygnanawkyctkv....fdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfgskvt

KELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKSIQGIDGED
||...  ........ ..|.||... ....|.|. |         |   ..... ... ..| .. .. |.
kefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklfkavpdee
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 39-298 1.9e-33 109.0 In-house 30-292 (297) alignment 
Range on Protein: 39-298
Range on HMM: 30-292/297.0
ELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSF
.||. ||...     .  .  |...||||. .. |.| .|.  |||   .|.|||. .| |.||.||.|.||. |. .| |...||| .| |.|.    |
klldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhecefvnkvygf

IGELRVRFPDSNKWQALNaiikSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDIDIPSPVT---PNKIDEE----S
  | . |.     . |..     ... ||.. ..  |.||. | ..  . .|  . .... .  .. . |.  ..|  |  | ..    |.         
yeecqkryqsvrmyaafq....dvfnwlpltgliatkilcmhgglsplltkeftldtlrkierstegkerlvadllwadpisglsgfmenqrgagcgfgr

KIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKSI
  . .|   ... ..  . .||..|| |    .|.|| |  .   ...|   .|  | . .. |. .
davlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeil
subfamily_PPP4C_pd Subfamily PPP4C 39-297 1.3e-32 106.2 In-house 23-281 (288) alignment 
Range on Protein: 39-297
Range on HMM: 23-281/288.0
ELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSF
.| ..| ||.   | |. .  || .||||  .. |.|..||  |   |..|.|||...| |..|.||...||. |. ||.. ...|| .|   .     |
alcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqitqvygf

IGELRVRFPDSNKWQALNAIIksllKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDID-IPS-PVTPNKID--EESKII
  |   .. ..| |.    ..      |.. .... |..|| | .. .|..  .. |.   .   .. . ... . | . . .  |.|        |...
ydeclrkygsanvwryctevf....dylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgsdvv

KELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKS
... .. |..... . ..| |||.. ......|. |         |   .. .| . . .|| 
eqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfki
subfamily_PPPLV_pd Subfamily PPPLV 39-198 1.3e-17 57.0 In-house 4-165 (290) alignment 
Range on Protein: 39-198
Range on HMM: 4-165/290.0
ELLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDvLDIFKTCGWPF-----EQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVK
 | . |..|.    |.  .  |. . ||.   | | | .|.   |         ...|||. .| |.||.| .  ||  |. ||  ...||| .| | |.
slcdvavdilaaeerllelksptyvlgdlhgnyrd.liyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvq

SDRSFIGELRVRFPDSN--KWQALNAIikslLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKN
 .  . ||   .| ||    |.|.|..    .. ||. .|..||..|| . .   |. .  . ....
esieykgegsfkfgdsleevweafnnv....fdalplaavidrkvfcvhagipraimtqayisaiqd
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 40-293 6.2e-33 107.4 In-house 11-266 (284) alignment 
Range on Protein: 40-293
Range on HMM: 11-266/284.0
LLEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFI
|| .|..|..    .  .  |.||||||. .. |.| .|   |.|   .|.|||. .| ||  |||...|.. |. .|. |..||| .|  |..    | 
llfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiygfy

GELRVRFPDSNKWQALNAIIksllKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNT-RVEVQFLD-IDIPSPVTPNKID----EESKI
 | . |.     ..... ..      .|. ... ...||. | |.  ..|  .. ..|      . ||  ... . |  ..     ||         |  
eecqrrynkpsvyvsfegvf....svmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgsda

IKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKV
...||  ... ... . .||..|| |  . .|.|| |      ...|   || ...   .
lrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvc
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 41-297 9e-40 129.6 In-house 15-271 (280) alignment 
Range on Protein: 41-297
Range on HMM: 15-271/280.0
LEDALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIG
.|   .|.   . .  .  ||..|||.  .| |.| .|. ...| .|.|.|||. .| |.. || ...||. |. ||.||.|||| .|   ..    |  
iekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevisinrkygfkd

ELRVRfpdsnKWQALNAIIKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGnmFENHNTRVEVQFLDIDIP---SPVTPNKI----DEESKI
| . |       .|| . .. ||. ||...... ..||. | .. ...  ...  ..    |....  .. ..|  |     .  . |         ...
evkrr.....yslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrp..fdsedeclamdllwadpenkvtgwaensrgvsvifganv

IKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKS
.|.| . .|. ...   .||..|| |  ...|.|. |  |  ....|   |...| . .| |. 
vkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfev
subfamily_PPG1_pd Subfamily PPG1 43-295 1.3e-23 76.8 In-house 25-290 (300) alignment 
Range on Protein: 43-295
Range on HMM: 25-290/300.0
DALEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGEL
   |..   | |  |  || . ||.  .. |||.|||  |   . .|.|||. .| | .|.||...|.. |. ||    .||| .|   .     | .| 
klkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhesrqitqvygfytec

RVRF-PDSNKWQALNAIIksllKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDIDIPSPVTPNKIDEES----------
  ..  .|. |. |  |.      | . .... .. || | .. ...   ..  .   .   |. .  .. . | .  .  | .. |.|           
lrkyggnsrvwkylteif....dylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdregqhfvvsqrga

------KIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNF
      ......|.  ||  .| . ... |||.  . |.| |. |  .  .   |.  .. .  ...  |
gysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyf
subfamily_PPZ_pd Subfamily PPZ 45-302 6.1e-31 101.0 In-house 38-295 (300) alignment 
Range on Protein: 45-302
Range on HMM: 38-295/300.0
LEIMDGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGELRV
 |..     .  ..|.|.| ||.. .|.|.| .|  ||.|   .|.|||. .| || ||||...||| || ||.||..||| .|   |     |  | . 
relflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnhecanvtrvygfydeckr

RFpDSNKWQALnaiIKSlLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLD-IDIPSPVTPNKID----EESKIIKELLK
|  . . |...   . . .. ||. ...  |..|| | ..  ...  ..  |       .     .. . |  | .     |.       .   |...|.
rc.nikiwktf...vdt.fntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptdssnewednergvsycynkvainkfln

SMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKSIQGID
 . . ..  .  || .|| |     |.|. |  .   ...| | || .     ..|. .. .|
kfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfelldpld
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 49-297 7.2e-28 90.6 In-house 25-273 (281) alignment 
Range on Protein: 49-297
Range on HMM: 25-273/281.0
DGTSRVEYITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGELRVrfpd
   . .  | .|. . ||. ... |.  .|.  | . |...||||. .| |. |||.|..|.. ||.|... |.||| .|   |.    |  |  .    
seekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasvnkiygfyvecvt....

sNKWQALNAIIKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVknGNMFENHNTRVEVQFLDIDIPSPVTPNKID-------EESKIIKELLKSM
    . | | ... . |||. .  ... ||. | .. .. .  ..      .  .| .  . . .|  |  . |   |            .....  |..
.kyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnr..pkpirnldrGlviDllwadpdnkveewkassrGssftfGknvvddvckrl

DMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKS
.. ..| .  || .||.     .|||. |  .  . |.| ..|. .|   ......
eveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislva
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 56-295 8.5e-32 103.6 In-house 48-288 (299) alignment 
Range on Protein: 56-295
Range on HMM: 48-288/299.0
YITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGELRVRFPDSNKWQal
 . .|. .||||  .| |.| ||.  |.| . ...|||. .| |.  ||....||| || ||..| .||| .|   ..    |  |   |.  .  |   
eveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhecpainrvygfyeecnkrykstrlws..

naIIKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDIDIPSP-VTPNKI----DEESKIIKELLKSMDMSMMINSN
  |..  .. .|.. ... ..||. | .. ....  ..  .   .   |    ... . | |       .|          ..... .. .|. ..  . 
..ifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqsvkdwlanvrgvsyvfgqdvvadvisrldidlvarah

NVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNF
.||..|| |  ...|.|| |  .   ...|   .| .|    . |
qvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctf
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 56-297 1.3e-29 96.6 In-house 32-279 (284) alignment 
Range on Protein: 56-297
Range on HMM: 32-279/284.0
YITPPVNICGDIRSRYGDVLDIFKTCGWP------FEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGELRVRFPds
 |  ||.|.|||  .. |.| ...  |||       |.||.|||. .| | ||.| ...|.. |. .|.. ..||| .|   |. .  |  | . |.   
eieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrgnhesrpvnmqygfyleckkrys..

nkwQALNAIIKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHNTRVEVQFLDIDI------PSPVTPNKIDEeSKIIKELLKSMDM
   .||  ...  .. .|...|...|..|. | .. .. . |..  ..      .     .. . | .        ||    |.   .| .||.|| ...
...ealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegykesprgagkvfg.akavkeflkkfkl

SMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKS
 ... . .|| .|| |   ..|.|| |      ...| . |. .|..  . |. 
dlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftv
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 57-193 7.6e-17 54.6 In-house 31-162 (280) alignment 
Range on Protein: 57-193
Range on HMM: 31-162/280.0
ITPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGELRVRFPDSNKWQaln
   |... |||...| |.  .|   |   |.| .|||. .| |   .| |..|.| || | .   .||| .|   |.    |  | . ..     |.   
aeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnkiygfyvecqykygvglwwd...

aiIKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNV
  ..| ..|.|.  ......||. | .. .. |   .
..fqscfnrmpmsgliskrvlcmhgglspelinldti
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 58-307 1.2e-32 106.7 In-house 6-262 (263) alignment 
Range on Protein: 58-307
Range on HMM: 6-262/263.0
TPPVNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGELRVRFPDSNKWQALNA
  |.||||| . .| |.| ||..||   . .|.|||. .| | .||| ...|.  |.. |... .||| .| . .. .  |  ||. ||   . ....  
qapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevyesvyn

IIKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNG-NMFENHNTRVEVQFLDIDIP-SPVTPNKIDEESKI-----IKELLKSMDMSMMINSN
 .. ..  .|. .......||. | ..  .|.  .. ..    .  . |   ... . | .     . ||||   |..     . .| | .|. ... . 
hfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidlivrah

NVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKSIQGIDGEDRT
.||  || |    .|||. | .. | .  |   |.....  ...|  ..  | | | 
qvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkpedfevrr
Metallophos Calcineurin-like phosphoesterase 60-125 5e-07 23.2 Pfam-A 2-73 (200) alignment 
Range on Protein: 60-125
Range on HMM: 2-73/200.0
PVNICGDIRSRYGDV----LDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVIL--LCCKICYPQNFVILRG
.. ..||.   . |     | ..| .. .  . ..||| |.|.|. |.||| .|  |. |. .| ... |||
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrG
PPP_2 61-206 6.6e-30 97.3 In-house 1-142 (198) alignment 
Range on Protein: 61-206
Range on HMM: 1-142/198.0
VNICGDIRSRYGDVLDIFKTCGWPFEQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGELRVRFPDSNKWQALNaiik
|..|||.  .. |.| .||... . |.||.|||. .| ||.|||.|..||..|. ||.....|||  |.. | .   |  |.  .  ... ...|.    
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklq....

SLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNGNMFENHN
.. . ||. .....|.|.| | ....||..... . .. .  ....
evfelLplaalidekvlvvHGGlseeiklldqikkeerkiespeeg
PPP_4 61-198 1.3e-26 86.9 In-house 1-135 (197) alignment 
Range on Protein: 61-198
Range on HMM: 1-135/197.0
VNICGDIRSRYGDV-LDIFKTCGWPF-EQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGELRVRfpdsnKWQALNAI
| ..|||  .. |. | ..|. | |  |..|||||. .| ||.|||.|..||..|. ||...|.|||  | . ...  .|  |.  .     . . .  .
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek.....hgkeilkk

IKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKN
.. . . ||. .....|.|.| | . ..... ...  ...
lqdvfdllplaalidekvlvvhgglsdelesldkierier
PPP_5_Dcr2 61-199 1.7e-26 86.5 In-house 1-137 (199) alignment 
Range on Protein: 61-199
Range on HMM: 1-137/199.0
VNICGDIRSRYGDV-LDIFKTCGWPF-EQKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGELRVRFpdsnKWQALNAI
| .|||.  ...|. | .||..| |  |..|||||. .|.||.|||.|..||..|. ||.....|||  | | ...  .|  |   ..    . . .  |
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlsky....hgkkiyki

IKSLLKRLPVMTVLNRKLLCVNGMVTSNIKNEKNVVSVKNG
.. . . ||. .....|.|.| | . ..||. ...  ... 
lsdvfdwlPlaalidekvlvvhgglspeiksiellekierk
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 87-297 6.5e-24 77.7 In-house 101-311 (317) alignment 
Range on Protein: 87-297
Range on HMM: 101-311/317.0
QKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGELRVRFPdsnkwQALNAIIKSLLKRLPVMTVLNRKLLCVNGMVTSN
.||.|||. .| | ||.| ...|.. |. ||.. ..||| .|   |  .  |  | . |.      .||  . .  .. ||. .|.| |.||. | .. .
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrys.....aalyeafqlafnvlplcavvnkkilcmhGGisee

IKNEKNVVSVKNGNMFENHNTRVEVQFLDIDI------PSPVTPNKIDEeSKIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNN
. . |..  .|      .     .. . | |       .|.    |.   .| .||.|| .|. ... . .||..|| |    .|.|| |  .   . .|
lldlkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfG.akavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldn

RGVVMMMDRHNKVNFKS
 . |. .|.. |. .. 
iaavlsvdkklkisinv
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 87-296 1.3e-19 63.5 In-house 120-329 (339) alignment 
Range on Protein: 87-296
Range on HMM: 120-329/339.0
QKYVFLGNLIDGGKFSLETLVILLCCKICYPQNFVILRGFYEHELVKSDRSFIGELRVRFpDSNkwqaLNAIIKSLLKRLPVMTVLNRKLLCVNGMVTSN
..|.|||. .| | ||.| ...| . |..||.   .||| .|   |..   |  |.  |. |..    |   .. ... .|. .|.|  ..|. | ..  
krylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyry.daq....lyecfqnmfnvfpfcavinntimcmhggiseh

IKNEKNVVSVKNGNMFENHNTRVEVQFLDIDIPSPV-TPN----KIDEESKIIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNR
.   ...  .|      .     .. . | |       |      .      .. .|| .|. |.|   .|| .|| |    .|.|| |  .   . .| 
ltsfnqfsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndnt

GVVMMMDRHNKVNFK
  |. .|.. |.  .
aavfsidkklkisin
subfamily_PPP7C_pd Subfamily PPP7C 233-292 2.4e-06 19.5 In-house 267-326 (383) alignment 
Range on Protein: 233-292
Range on HMM: 267-326/383.0
IIKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNK
. |.||.  .....| | .   ||| |. .....|| | .   ..  |||  . . .. .
vtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdlt
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 234-298 6.3e-09 28.4 In-house 233-297 (302) alignment 
Range on Protein: 234-298
Range on HMM: 233-297/302.0
IKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKSI
.... | ....... . ... ||..|  ...|.|| | .. . . .|.| |. .|   |..  ..
vrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvl
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 234-298 7.1e-09 28.3 In-house 234-298 (302) alignment 
Range on Protein: 234-298
Range on HMM: 234-298/302.0
IKELLKSMDMSMMINSNNVVREGYRFTLKNQLITITSGTKLQKNYNNRGVVMMMDRHNKVNFKSI
.... | ....... . ... ||..|  ...|.|| | .. . . .|.| |. .|   |..  ..
vrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvl