Gene F33G12.6 in Caenorhabditis elegans

Synonym: CELE_F33G12.6, F33G12.6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily CG9801
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP075_AA protein Get Run
CeleP075_AA_204-399 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_CG9081_pd Subfamily CG9081 205-390 1.8e-73 236.9 In-house 1-192 (195) alignment
Range on Protein: 205-390
Range on HMM: 1-192/195.0
AGEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIK-DSLADTTEVFHEMLAAFHSAHSLILQEGGMLTTLCVALVAPVRR--
||||.|||..|| |.|| .||||||||||. ||||||.|..||...|| .. | .. ... ..|. .| ... |.. ||...| ||||..|.|. ..   
agePvadvfavvarennaimaladGvnWGkkarlaarsavagavaylndklfklsakpnsrdlfklllesleeaqksilensgtlttlsiavvcelkank

--GNGWALCVCNVGDSLCFVYNRHYG-VREVTLGSHDIDQMRDMRDAGGALGPVDGRNPQLHNLTCSMTFVEEGDVVFITSDGVSDNFDPVV
   . |.|.| .||||..|||..... |||||..||. | .||.|..||||||..| .| |.||..|.. |.|||.||.|||||||||||||
kissqWglfvvsvGdspvfvyspdnksvrevtvashskdgirdvrlsGGalGpaiGtdpdlenlslsylpvaeGdivfltsdGvsdnfdPvv

subfamily_CG9801_pd Subfamily CG9801 205-402 2.9e-71 229.8 In-house 2-228 (252) alignment
Range on Protein: 205-402
Range on HMM: 2-228/252.0
AGEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIKDSlADTTEVFHEMLAAFHSAHSLILQEGGML-----TTLCVALVAPV
.|.||||...|| |.|. ..|||||.||||....|||.|....||.|.....|.. ....||....|||...||. |......|     |||........
eGdPiaDkftvvvrknrlilalaDGcnWGerpaeaarsasaafidylskalskei.ttvqevgksllaaleeahksivegkselweaGtttLlggvllel

RR------------------------GNGWALCVCNVGDSLCFVYN-RHYGVREVTLGSHdiDQMRDMRDAGGALGP-VDGRNPQLHNLTCSMTFVEEGD
..                        .. |......|||...|.|. ....|...| |..  ....|.|||||.||| |....|.|.||....|.|||.|
ekeaekpesssqlgksevglsasnassskwgfvcasvGDckaflysakkkevtditkgnr..snlsDarDagGrLGPyveqgkPdLrnLklfftlveeeD

VVFITSDGVSDNFDPVVGKFCVIKKS-EHE
.....||||.||.||.. .... ... . |
iillvsDGvhDnlDPqtlgktprdlnlnae

PP2C_2 Protein phosphatase 2C 205-387 1.4e-13 43.7 Pfam-A 8-182 (212) alignment
Range on Protein: 205-387
Range on HMM: 8-182/212.0
AGEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIKDSLADTTEVFHEMLAAFH-------SAHSLILQEGGMLTTLCVALVA
.|.|  | ...   ..  ..| |||.   .... .||.| . |...| . . ..|........ ..... .       .|..   .   . |||..|...
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllavit

PvrrgNGwaLCVCNVGDSLCFVYNRHYGVREVTLgshdidqmRDMRDAGGALGPVDGRNPQLHNLTCSMTfVEEGDVVFITSDGVSDNFD
|    ..  ......||. ..|..|   |. ..         .| ... . .  .. .... .  . ... .|.|| .....|||||.. 
p....ge..ivffqiGDgaivvrdrdgevqllge........pdsgeyanettfltsedaeeelrirrlk.lepgdalllmTDGvsdslr

PP2C_2 Protein phosphatase 2C 205-387 1.4e-13 43.7 In-house 8-182 (212) alignment
Range on Protein: 205-387
Range on HMM: 8-182/212.0
AGEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIKDSLADTTEVFHEMLAAFH-------SAHSLILQEGGMLTTLCVALVA
.|.|  | ...   ..  ..| |||.   .... .||.| . |...| . . ..|........ ..... .       .|..   .   . |||..|...
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllavit

PvrrgNGwaLCVCNVGDSLCFVYNRHYGVREVTLgshdidqmRDMRDAGGALGPVDGRNPQLHNLTCSMTfVEEGDVVFITSDGVSDNFD
|    ..  ......||. ..|..|   |. ..         .| ... . .  .. .... .  . ... .|.|| .....|||||.. 
p....ge..ivffqiGDgaivvrdrdgevqllge........pdsgeyanettfltsedaeeelrirrlk.lepgdalllmTDGvsdslr

subfamily_tipA_pd Subfamily tipA 205-283 1.5e-13 40.2 In-house 6-82 (296) alignment
Range on Protein: 205-283
Range on HMM: 6-82/296.0
AGEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRviKDSLADTTEVFHEMLAAFHSAHSLILQ
.|.|||| . |. ..|  ..||||| |||.  . ||. |. . .|.|. .  .. .    .. . .|.||. ||  |..
egdpiadrftvqvyknrlivaladGcnWGkrPaeaatnasaafvdflsek..sseintvkdaGkfllsafeaahkkive

PP2Cc_SM00332 205-322 2.5e-08 26.7 In-house 20-139 (274) alignment
Range on Protein: 205-322
Range on HMM: 20-139/274.0
AGEPIADVWGVVGR----NNNGVMALADGvnwgEGARLAARCAIRGAIDHLNTRVIKDSLADTTEVFHEMLAAFHSAHSLILQEG--------GMLTTLC
. ... |.. || .    .. ......||    .|   .|... .   ..|. .  |..  .  .|   .  || |... ||.|         .. .|..
wrksmeDahvvvvdlveeedwlffgvfDG....hgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelenalsGstav

VALVAPVRrgngwaLCVCNVGDSLCFVYNR
|||..  .      | |.||||| ..... 
vallkked......lyvanvGDSravlcrn

subfamily_Sponge-PPM-1_pd Subfamily Sponge-PPM-1 206-390 9.8e-64 204.6 In-house 2-193 (199) alignment
Range on Protein: 206-390
Range on HMM: 2-193/199.0
GEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIKDSLAD--TTEVFHEMLAAFHSAHSLILQEGGMLTTLCVALVAPV----
|||.|||..|| |.|| .||.|||||||. .|||||||..||| ... .. | |     . .... .| ... ||  ||...| |||| .|.|  .    
GepvadvfavvarennaimaiadGvnwGkkprlaarcavqgaiayisdnlfklsakptnsrtltklllesldeahksileheGtlttlsiavvcelkpns

RRGNGWALCVCNVGDSLCFVYNRHY-GVREVTLGSHDIDQMRDMRDAGGALGPVDGRNPQLHNLTCSMTFVEEGDVVFITSDGVSDNFDPVV
|  . |.|.|  |||| .|||. ..  |.|.|   || | .|..|..||||||  | .| |.||..|.  |.|||.|..|.||.||||.|||
rsssrwglfvasvGdspvfvyspdtksvheatvachdkdGirtarlsGGalGpaiGtdpdlenlslsylpvaeGdivllttdGisdnfapvv

0034914 PP2C-like 208-387 3.5e-12 39.0 In-house 34-245 (295) alignment
Range on Protein: 208-387
Range on HMM: 34-245/295.0
PIADVWGVVG-----RNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRvIKDSLADTTEVFHEMLAAFHSAHSLILQE-------GGMLTTLCVAL
.  | . ||       .. ......||..  . |..|.. ...  ...|.   .  .  ... . . .  ||..|.  .|..        |. ||..|||
sneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekl.lllltlsledieealrkaflaadeellelallrpelagsGtTavval

VapvrrgNGWALCVCNVGDSLCFVYnRHYGVREVTLGSHDID--QMRDMRDAGGAL---------------GPVDGR--------------NPQLHNLTC
.       |  | |.||||| .... |.  .. .|   .  .   .. ...||||                | .|                 |... |..
i......rgnklyvanvGDSravll.rngelvqltvdhkpvnelererilsaggavshgrvngvlavtRalGdfdlklllslllleplvsaePdvtvlel

SmtfVEEGDVVFITSDGVSDNFD
.   .|..|.. . |||..|...
t...ledddfllLasDGlwdvls

0049733 PP2C-like 211-388 9.4e-18 57.6 In-house 20-194 (235) alignment
Range on Protein: 211-388
Range on HMM: 20-194/235.0
DVWGVvgrnNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIKDSLADTTEVFHEMLAAFHSAHSLILQEGGMLTTLCVALVApvrrgnGWALCVC
| . |    . ...|.|||.. ......|......  ...| .  . | ..  ...|... .|...      .  || ||..|||.       |  |.|.
Davlv....glllfavaDGhgghaagevasellvetllelllelllldleealrkaflaaneallelalaspelagmgtTavvalld......ggklyva

NVGDSLCFVYNrHYGVREVTLGSHDIDQMRDM--RDAGGALgpvdgRNPQLHN-----------LTCSMTFVEEGDVVFITSDGVSDNFDP
||||| ..... .  .. .|   .  ... ..  ..||||.     | |. .               ... .|.||.....|||..|....
nvGDsrayllr.dgklvqltedhspvnelerqriitaggav.....rvpgrlaltralGdlllkpdvtvlelepgdflllasDGlwdvlsd

PP2C_SIG_SM00331 212-386 5.8e-13 41.9 In-house 20-164 (217) alignment
Range on Protein: 212-386
Range on HMM: 20-164/217.0
VWGVVGRNN-NGVMALADGVNWGEGARLAARCAiRGAIDHLNTRVikdslADTTEVFHEMLAAFHSAhsliLQEGGMLTTLCVALVaPVRRGNgwaLCVC
. .||  |.   ....|||.  |  | .|.. . |.|...| ..       .........  |...      .|.|| .||..||. . ..|.   | ..
yydvvklnegrlllvvaDgmGkGlaAaaassql.rtalrellseg.....eelsqalkrlnraiyee....keekgmfaTlllaly.dfssgk...lsya

NVGDSLCFVYNrHYGVREVTLGshdidqmrdmrDAGGALGPVDGRNpqlhnLTCSMTFVEEGDVVFITSDGVSDNF
|.||| .....   .  | .              .| .||  . ..     .. ... .|.||.... .||. .. 
naGdsrpyllr.dgklveilkd...........vegaplGlepevs.....vdirelelekgdllllytDGltear

PPM_PTC7_SpoIIE 253-386 5.4e-06 19.4 In-house 60-170 (230) alignment
Range on Protein: 253-386
Range on HMM: 60-170/230.0
TRViKDSLADTTEVFHEMLAAFHSAH--SlilqEGGMLTTLCVALVAPVRrgngWALCVCNVGDSLCFVYNRHYGvrevtlgshdidqmrD---MRDAGG
..  . .| .  |....  .|.. ..  .    .. . .|..|||. | .    . | |.|.||| ..... . |                       | 
ela.faglekpeeilrrlnlalaadlede....psssgaTavvalidpst....gklyvanaGdsppllvrddgg...............ererivaggl

A-LGPVDGRNPQLHNLTcsmtfVEEGDVVFITSDGVSDNF
. ||  .||  . ....      ..||. .  .||| .. 
pslGilpgrvfgvlavs.....lapGdllllytDGvveae

SpoIIE Stage II sporulation protein E (SpoIIE) 257-391 5.1e-06 18.4 Pfam-A 39-143 (193) alignment
Range on Protein: 257-391
Range on HMM: 39-143/193.0
KdsladttevFHEMLAAFHSAHSLILQEGGMLTTLCVALVAPVRRgngwALCVCNVGDSLCFVYNRHYgvrevtlgshdiDQMRDMRDAGGALGPVDGrn
.         ..|.|.. ..| .  |.|. . .|...| . | ..     | ..|.|.. .......             ..     . | .|| ...  
e.........paevlerlnealarnleeeerfatavlaeydpstg....kleyanaGhpppllvrpdg............gtkfllvstglplGilpe..

pqlHNLTCSMTFVEEGDVVFITSDGVSDNFDPVVG
   .. ..    .|.||.... .||| .. ||  .
...adyeeaelqlepgdllllyTDGvtEardpdge

SpoIIE Stage II sporulation protein E (SpoIIE) 257-391 5.1e-06 18.4 In-house 39-143 (193) alignment
Range on Protein: 257-391
Range on HMM: 39-143/193.0
KdsladttevFHEMLAAFHSAHSLILQEGGMLTTLCVALVAPVRRgngwALCVCNVGDSLCFVYNRHYgvrevtlgshdiDQMRDMRDAGGALGPVDGrn
.         ..|.|.. ..| .  |.|. . .|...| . | ..     | ..|.|.. .......             ..     . | .|| ...  
e.........paevlerlnealarnleeeerfatavlaeydpstg....kleyanaGhpppllvrpdg............gtkfllvstglplGilpe..

pqlHNLTCSMTFVEEGDVVFITSDGVSDNFDPVVG
   .. ..    .|.||.... .||| .. ||  .
...adyeeaelqlepgdllllyTDGvtEardpdge

subfamily_tipA_pd Subfamily tipA 304-392 1.2e-15 47.1 In-house 152-241 (296) alignment
Range on Protein: 304-392
Range on HMM: 152-241/296.0
GWALCVCNVGDSLCFVYNRH-YGVREVTLGSHdiDQMRDMRDAGGALGP-VDGRNPQLHNLTCSMTFVEEGDVVFITSDGVSDNFDPVV-GK
 | .    |||   | . ..   | ..| |      . | .|.|| ||| |.  .| | ||.  ....|| |.... |||| ||.||   ||
kWgfvcasvGdckafllskkskevtditkgnr..snvddakdpGGrlGPyveqGkPdlrnlklffllceeediillvsdGvhdnldPktlgk