Gene F33G12.6 in Caenorhabditis elegans

Synonym: CELE_F33G12.6, F33G12.6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily CG9801
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP075_AA protein Get Run
CeleP075_AA_204-399 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_CG9081_pd Subfamily CG9081 205-390 1.8e-73 236.9 In-house 1-192 (195) alignment 
Range on Protein: 205-390
Range on HMM: 1-192/195.0
AGEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIK-DSLADTTEVFHEMLAAFHSAHSLILQEGGMLTTLCVALVAPVRR--
||||.|||..|| |.|| .||||||||||. ||||||.|..||...|| .. | .. ... ..|. .| ... |.. ||...| ||||..|.|. ..   
agePvadvfavvarennaimaladGvnWGkkarlaarsavagavaylndklfklsakpnsrdlfklllesleeaqksilensgtlttlsiavvcelkank

--GNGWALCVCNVGDSLCFVYNRHYG-VREVTLGSHDIDQMRDMRDAGGALGPVDGRNPQLHNLTCSMTFVEEGDVVFITSDGVSDNFDPVV
   . |.|.| .||||..|||..... |||||..||. | .||.|..||||||..| .| |.||..|.. |.|||.||.|||||||||||||
kissqWglfvvsvGdspvfvyspdnksvrevtvashskdgirdvrlsGGalGpaiGtdpdlenlslsylpvaeGdivfltsdGvsdnfdPvv
subfamily_CG9801_pd Subfamily CG9801 205-402 2.9e-71 229.8 In-house 2-228 (252) alignment 
Range on Protein: 205-402
Range on HMM: 2-228/252.0
AGEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIKDSlADTTEVFHEMLAAFHSAHSLILQEGGML-----TTLCVALVAPV
.|.||||...|| |.|. ..|||||.||||....|||.|....||.|.....|.. ....||....|||...||. |......|     |||........
eGdPiaDkftvvvrknrlilalaDGcnWGerpaeaarsasaafidylskalskei.ttvqevgksllaaleeahksivegkselweaGtttLlggvllel

RR------------------------GNGWALCVCNVGDSLCFVYN-RHYGVREVTLGSHdiDQMRDMRDAGGALGP-VDGRNPQLHNLTCSMTFVEEGD
..                        .. |......|||...|.|. ....|...| |..  ....|.|||||.||| |....|.|.||....|.|||.|
ekeaekpesssqlgksevglsasnassskwgfvcasvGDckaflysakkkevtditkgnr..snlsDarDagGrLGPyveqgkPdLrnLklfftlveeeD

VVFITSDGVSDNFDPVVGKFCVIKKS-EHE
.....||||.||.||.. .... ... . |
iillvsDGvhDnlDPqtlgktprdlnlnae
PP2C_2 Protein phosphatase 2C 205-387 1.4e-13 43.7 Pfam-A 8-182 (212) alignment 
Range on Protein: 205-387
Range on HMM: 8-182/212.0
AGEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIKDSLADTTEVFHEMLAAFH-------SAHSLILQEGGMLTTLCVALVA
.|.|  | ...   ..  ..| |||.   .... .||.| . |...| . . ..|........ ..... .       .|..   .   . |||..|...
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllavit

PvrrgNGwaLCVCNVGDSLCFVYNRHYGVREVTLgshdidqmRDMRDAGGALGPVDGRNPQLHNLTCSMTfVEEGDVVFITSDGVSDNFD
|    ..  ......||. ..|..|   |. ..         .| ... . .  .. .... .  . ... .|.|| .....|||||.. 
p....ge..ivffqiGDgaivvrdrdgevqllge........pdsgeyanettfltsedaeeelrirrlk.lepgdalllmTDGvsdslr
PP2C_2 Protein phosphatase 2C 205-387 1.4e-13 43.7 In-house 8-182 (212) alignment 
Range on Protein: 205-387
Range on HMM: 8-182/212.0
AGEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIKDSLADTTEVFHEMLAAFH-------SAHSLILQEGGMLTTLCVALVA
.|.|  | ...   ..  ..| |||.   .... .||.| . |...| . . ..|........ ..... .       .|..   .   . |||..|...
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllavit

PvrrgNGwaLCVCNVGDSLCFVYNRHYGVREVTLgshdidqmRDMRDAGGALGPVDGRNPQLHNLTCSMTfVEEGDVVFITSDGVSDNFD
|    ..  ......||. ..|..|   |. ..         .| ... . .  .. .... .  . ... .|.|| .....|||||.. 
p....ge..ivffqiGDgaivvrdrdgevqllge........pdsgeyanettfltsedaeeelrirrlk.lepgdalllmTDGvsdslr
subfamily_tipA_pd Subfamily tipA 205-283 1.5e-13 40.2 In-house 6-82 (296) alignment 
Range on Protein: 205-283
Range on HMM: 6-82/296.0
AGEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRviKDSLADTTEVFHEMLAAFHSAHSLILQ
.|.|||| . |. ..|  ..||||| |||.  . ||. |. . .|.|. .  .. .    .. . .|.||. ||  |..
egdpiadrftvqvyknrlivaladGcnWGkrPaeaatnasaafvdflsek..sseintvkdaGkfllsafeaahkkive
PP2Cc_SM00332 205-322 2.5e-08 26.7 In-house 20-139 (274) alignment 
Range on Protein: 205-322
Range on HMM: 20-139/274.0
AGEPIADVWGVVGR----NNNGVMALADGvnwgEGARLAARCAIRGAIDHLNTRVIKDSLADTTEVFHEMLAAFHSAHSLILQEG--------GMLTTLC
. ... |.. || .    .. ......||    .|   .|... .   ..|. .  |..  .  .|   .  || |... ||.|         .. .|..
wrksmeDahvvvvdlveeedwlffgvfDG....hgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelenalsGstav

VALVAPVRrgngwaLCVCNVGDSLCFVYNR
|||..  .      | |.||||| ..... 
vallkked......lyvanvGDSravlcrn
subfamily_Sponge-PPM-1_pd Subfamily Sponge-PPM-1 206-390 9.8e-64 204.6 In-house 2-193 (199) alignment 
Range on Protein: 206-390
Range on HMM: 2-193/199.0
GEPIADVWGVVGRNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIKDSLAD--TTEVFHEMLAAFHSAHSLILQEGGMLTTLCVALVAPV----
|||.|||..|| |.|| .||.|||||||. .|||||||..||| ... .. | |     . .... .| ... ||  ||...| |||| .|.|  .    
GepvadvfavvarennaimaiadGvnwGkkprlaarcavqgaiayisdnlfklsakptnsrtltklllesldeahksileheGtlttlsiavvcelkpns

RRGNGWALCVCNVGDSLCFVYNRHY-GVREVTLGSHDIDQMRDMRDAGGALGPVDGRNPQLHNLTCSMTFVEEGDVVFITSDGVSDNFDPVV
|  . |.|.|  |||| .|||. ..  |.|.|   || | .|..|..||||||  | .| |.||..|.  |.|||.|..|.||.||||.|||
rsssrwglfvasvGdspvfvyspdtksvheatvachdkdGirtarlsGGalGpaiGtdpdlenlslsylpvaeGdivllttdGisdnfapvv
0034914 PP2C-like 208-387 3.5e-12 39.0 In-house 34-245 (295) alignment 
Range on Protein: 208-387
Range on HMM: 34-245/295.0
PIADVWGVVG-----RNNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRvIKDSLADTTEVFHEMLAAFHSAHSLILQE-------GGMLTTLCVAL
.  | . ||       .. ......||..  . |..|.. ...  ...|.   .  .  ... . . .  ||..|.  .|..        |. ||..|||
sneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekl.lllltlsledieealrkaflaadeellelallrpelagsGtTavval

VapvrrgNGWALCVCNVGDSLCFVYnRHYGVREVTLGSHDID--QMRDMRDAGGAL---------------GPVDGR--------------NPQLHNLTC
.       |  | |.||||| .... |.  .. .|   .  .   .. ...||||                | .|                 |... |..
i......rgnklyvanvGDSravll.rngelvqltvdhkpvnelererilsaggavshgrvngvlavtRalGdfdlklllslllleplvsaePdvtvlel

SmtfVEEGDVVFITSDGVSDNFD
.   .|..|.. . |||..|...
t...ledddfllLasDGlwdvls
0049733 PP2C-like 211-388 9.4e-18 57.6 In-house 20-194 (235) alignment 
Range on Protein: 211-388
Range on HMM: 20-194/235.0
DVWGVvgrnNNGVMALADGVNWGEGARLAARCAIRGAIDHLNTRVIKDSLADTTEVFHEMLAAFHSAHSLILQEGGMLTTLCVALVApvrrgnGWALCVC
| . |    . ...|.|||.. ......|......  ...| .  . | ..  ...|... .|...      .  || ||..|||.       |  |.|.
Davlv....glllfavaDGhgghaagevasellvetllelllelllldleealrkaflaaneallelalaspelagmgtTavvalld......ggklyva

NVGDSLCFVYNrHYGVREVTLGSHDIDQMRDM--RDAGGALgpvdgRNPQLHN-----------LTCSMTFVEEGDVVFITSDGVSDNFDP
||||| ..... .  .. .|   .  ... ..  ..||||.     | |. .               ... .|.||.....|||..|....
nvGDsrayllr.dgklvqltedhspvnelerqriitaggav.....rvpgrlaltralGdlllkpdvtvlelepgdflllasDGlwdvlsd
PP2C_SIG_SM00331 212-386 5.8e-13 41.9 In-house 20-164 (217) alignment 
Range on Protein: 212-386
Range on HMM: 20-164/217.0
VWGVVGRNN-NGVMALADGVNWGEGARLAARCAiRGAIDHLNTRVikdslADTTEVFHEMLAAFHSAhsliLQEGGMLTTLCVALVaPVRRGNgwaLCVC
. .||  |.   ....|||.  |  | .|.. . |.|...| ..       .........  |...      .|.|| .||..||. . ..|.   | ..
yydvvklnegrlllvvaDgmGkGlaAaaassql.rtalrellseg.....eelsqalkrlnraiyee....keekgmfaTlllaly.dfssgk...lsya

NVGDSLCFVYNrHYGVREVTLGshdidqmrdmrDAGGALGPVDGRNpqlhnLTCSMTFVEEGDVVFITSDGVSDNF
|.||| .....   .  | .              .| .||  . ..     .. ... .|.||.... .||. .. 
naGdsrpyllr.dgklveilkd...........vegaplGlepevs.....vdirelelekgdllllytDGltear
PPM_PTC7_SpoIIE 253-386 5.4e-06 19.4 In-house 60-170 (230) alignment 
Range on Protein: 253-386
Range on HMM: 60-170/230.0
TRViKDSLADTTEVFHEMLAAFHSAH--SlilqEGGMLTTLCVALVAPVRrgngWALCVCNVGDSLCFVYNRHYGvrevtlgshdidqmrD---MRDAGG
..  . .| .  |....  .|.. ..  .    .. . .|..|||. | .    . | |.|.||| ..... . |                       | 
ela.faglekpeeilrrlnlalaadlede....psssgaTavvalidpst....gklyvanaGdsppllvrddgg...............ererivaggl

A-LGPVDGRNPQLHNLTcsmtfVEEGDVVFITSDGVSDNF
. ||  .||  . ....      ..||. .  .||| .. 
pslGilpgrvfgvlavs.....lapGdllllytDGvveae
SpoIIE Stage II sporulation protein E (SpoIIE) 257-391 5.1e-06 18.4 Pfam-A 39-143 (193) alignment 
Range on Protein: 257-391
Range on HMM: 39-143/193.0
KdsladttevFHEMLAAFHSAHSLILQEGGMLTTLCVALVAPVRRgngwALCVCNVGDSLCFVYNRHYgvrevtlgshdiDQMRDMRDAGGALGPVDGrn
.         ..|.|.. ..| .  |.|. . .|...| . | ..     | ..|.|.. .......             ..     . | .|| ...  
e.........paevlerlnealarnleeeerfatavlaeydpstg....kleyanaGhpppllvrpdg............gtkfllvstglplGilpe..

pqlHNLTCSMTFVEEGDVVFITSDGVSDNFDPVVG
   .. ..    .|.||.... .||| .. ||  .
...adyeeaelqlepgdllllyTDGvtEardpdge
SpoIIE Stage II sporulation protein E (SpoIIE) 257-391 5.1e-06 18.4 In-house 39-143 (193) alignment 
Range on Protein: 257-391
Range on HMM: 39-143/193.0
KdsladttevFHEMLAAFHSAHSLILQEGGMLTTLCVALVAPVRRgngwALCVCNVGDSLCFVYNRHYgvrevtlgshdiDQMRDMRDAGGALGPVDGrn
.         ..|.|.. ..| .  |.|. . .|...| . | ..     | ..|.|.. .......             ..     . | .|| ...  
e.........paevlerlnealarnleeeerfatavlaeydpstg....kleyanaGhpppllvrpdg............gtkfllvstglplGilpe..

pqlHNLTCSMTFVEEGDVVFITSDGVSDNFDPVVG
   .. ..    .|.||.... .||| .. ||  .
...adyeeaelqlepgdllllyTDGvtEardpdge
subfamily_tipA_pd Subfamily tipA 304-392 1.2e-15 47.1 In-house 152-241 (296) alignment 
Range on Protein: 304-392
Range on HMM: 152-241/296.0
GWALCVCNVGDSLCFVYNRH-YGVREVTLGSHdiDQMRDMRDAGGALGP-VDGRNPQLHNLTCSMTFVEEGDVVFITSDGVSDNFDPVV-GK
 | .    |||   | . ..   | ..| |      . | .|.|| ||| |.  .| | ||.  ....|| |.... |||| ||.||   ||
kWgfvcasvGdckafllskkskevtditkgnr..snvddakdpGGrlGPyveqGkPdlrnlklffllceeediillvsdGvhdnldPktlgk