Gene F42G8.8 in Caenorhabditis elegans

Synonym: CELE_F42G8.8, F42G8.8

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily CelePPP-sf5
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP083_AA protein Get Run
CeleP083_AA_24-323 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 9-321 4.3e-87 284.9 In-house 3-291 (298) alignment
Range on Protein: 9-321
Range on HMM: 3-291/298.0
VNMFLKRHLIVKSWANYRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYnvpkddakkkSGYGFCNNrFVFLGDYVDRG
|. .| ..|.|   ..      ..... .||.|..  .|. .|| .. .|... ||||||. ||.|...           .|.   .| ..|||||||||
vdellievlsvslsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdk..........agfppdan.ylflGdyvdrG

SHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLGPADgkeVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPl
....| | |..| |. |..|..|||||||. |||  ||| ||  .|        ....|..||. .||..|.|..|||||||.|..|..|......  | 
rqnlevivlllaykvkypnnffllrGnheceainrvyGfyeeckrrykslr...lyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrp.

FEIGNDSLAQDLLWADPTDGQgliavsqtPAYPKNiVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATL
|.  ..||| |||||||.. .          . .|  || |||| | .|.| ...| | |.|||||.. .|..|||..||.||||||.|... ||  |..
fdskeeslaidllwadpenav........kgwaen.srGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavm

KVETNGRLSIGRL
||. .  .|   |
kvdeklvvsfevl

subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 9-313 5.8e-75 245.3 In-house 3-283 (299) alignment
Range on Protein: 9-313
Range on HMM: 3-283/299.0
VNMFLKRHLIVKSWANYRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNvpkddakkksGYGfCNNRFVFLGDYVDRG
|. .| . | |    .       . ||..| ..   .. ...|| .. .|. ..||||||. ||.||.. .          |.   .  |.|||||||||
vdellskllnvgmsekrltksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdka..........gfp.pdvnflflgdyvdrg

SHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLgpaDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPL
   .| |.|... || |. .. .||||||  |||  ||| ||  .|        .|  |.. ||.|||. |.| .|||||||.||.|.||. ....  | 
rqnlelitlllcfkikyperffmlrgnhecpainrvygfyeecnkry...kstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpq

fEIGNDSLAQDLLWADPTDgqgliAVSQtpaYPKNiVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATL
 .  | ||  ||||||| .      | .   .  | |||.| || .  |.|...||.| |. ||||.. .|..|||..||.|||||| |  . ||  |..
.dppnpslgidllwadpdq.....svkd...wlan.vrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaim

KVETN
||. |
kvden

subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 12-312 1.4e-64 211.2 In-house 3-280 (307) alignment
Range on Protein: 12-312
Range on HMM: 3-280/307.0
FLKRHLIVKSwANYRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKddakkksgygfCNNRFVFLGDYVDRGSHS
||.||  |   |  ....||| |. ..|      .  ...| .| ||. .|||.|||| ||| ..                  .  .|| |||||||  |
fldrhyqviq.agvhkiqytkeefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrp...........petvyvftgdyvdrglls

IECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLgPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEI
.||| |.|. ||.|  | .|||||||   .|  ||| || |  . |  |.|.|  |. .|  .|...|.  ||||||||.|| |  |....|  .|. . 
lecilllftykicypenivllrgnheiarvnkkygfyeecvtsi.pkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnp

gNDSLAQDLLWADPTDgqgliAVSQTpaypKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVE
    . .|.|||||       .| .     |   ||  . |    . | |||||..||.|||||  .|.  .. .||.|||||| | |   | |. |||.
.frgivndmlwadpdp.....svfew....kassrgsgftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvd

T
 
e

subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 24-324 5.8e-173 567.0 In-house 1-301 (302) alignment
Range on Protein: 24-324
Range on HMM: 1-301/302.0
NYRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKDDAKKKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKI
.||. ||.||||..||. |. .||....||.|||||||||||||||.||.||||..|.|..||||| |.|....||||||||||||.|||||.|.||||.
kyrkkeysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkv

IYQTNYILLRGNHETRAINYAYGFREELVNRLGPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGNDSLAQDLLWA
.|.||||||||||||.|||.||||||||.||||..||||.||||||||..||||.||||||||.||||||.|..|||||.|..||.|...||||||||.|
lyptnyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfa

DPTDGQGLIAVSQTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRN
||.|.|.|.|||..|.| ||||||||||||||||.|.||||..|||||||||||||||||||.||||||||||||||.||.||.|||.|||.|||..|||
dpldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrn

M
 
k

subfamily_PPP1C_pd Subfamily PPP1C 24-318 5.6e-85 277.9 In-house 4-273 (282) alignment
Range on Protein: 24-318
Range on HMM: 4-273/282.0
NYRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYN-VPKDDakkksgygfcnnRFVFLGDYVDRGSHSIECISLMFALK
. .... ...|. .|..    .|...  | ... ||.||||||||..||.|..... .|..             ...|||||||||..|.| | |..|.|
kgkevklkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpes............nylflGdyvdrGkqsletivlllayk

IIYQTNYILLRGNHETRAINYAYGFREELVNRLGPAdgkeVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLfEIGNDSLAQDLLW
| |..|  |||||||.  ||  ||| .|  .|..      .|..|..||...||| || |||||.|||.||.|. ||.|..|  || |. ...|. ||||
ikypenlfllrGnhesasinriyGfydeckrrysik....lWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPl.evpekgllcdllW

ADPtDGQgliavsqTPAYPKNIvRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSI
.|| | .       .  . .|  || |..|.. .|.. ...  ..|||||||.. .|..|||...|.|.|||| |..| ||.|| |.|...  .| 
sdp.dke.......vlgwsend.rGvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsf

subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 25-325 6.2e-174 570.3 In-house 1-301 (302) alignment
Range on Protein: 25-325
Range on HMM: 1-301/302.0
YRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKDDAKKKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKII
||. ||.||||..||. |. .||....||.|||||||||||||||.||.||||..|.|..||||| |.|....||||||||||||.|||||.|.||||..
yrkkeysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvl

YQTNYILLRGNHETRAINYAYGFREELVNRLGPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGNDSLAQDLLWAD
|.||||||||||||.|||.||||||||.||||..||||.||||||||..||||.||||||||.||||||.|..|||||.|..||.|...||||||||.||
yptnyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfad

PTDGQGLIAVSQTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRNM
|.|.|.|.|||..|.| ||||||||||||||||.|.||||..|||||||||||||||||||.||||||||||||||.||.||.|||.|||.|||..|||.
pldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrnk

K
|
k

0045823 Metallo-dependent phosphatases 25-322 7.6e-91 298.1 In-house 38-322 (473) alignment
Range on Protein: 25-322
Range on HMM: 38-322/473.0
YRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYN--VPKDdakkksgygfcnnRFVFLGDYVDRGSHSIECISLMFALK
...  .....|..|.| ..  ||. ..| ..|......||||||..||.|.|. .   |.|             |.|||||.||||..|.|.. |..|||
kkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfpped.............rlvflGDlvDrGpdslevlelllalk

IIYQTNYILLRGNHETRAINYAYGFREELVNRLGPAdgkeVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLfEIGNDSLAQDLLW
| | .| .|||||||.|..|..|||..|.  ..|      ..| |.|.....|||...|.|||..|||.|| |..|..|..|. || || .|.|. ||||
ikypgnvfllrGNHElrllnglygfgdetlekyged....lyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpl.eipddgllldllw

ADPtDGQGLIAVSQTPAYPKNIvRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQK------LLTIFSAPRYMNETDNHGATLKVETNGrL
.|| . . .   .... .. .  || ...|.. ||.. .|. |..||||.|.. |||.... | |      ..|.|||| |.....| .| |... .. .
sdP.weddgdgllrlrffgnsp.rgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.i

SIGRLR
|.  ..
sfiqfd

subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 25-318 9.7e-74 241.1 In-house 3-271 (281) alignment
Range on Protein: 25-318
Range on HMM: 3-271/281.0
YRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNvpkddakKKsgygFCNNRFVFLGDYVDRGSHSIECISLMFALKII
  ...||| |....|  |   . |...|..| .|...|||.|.||.||.|...          .      ....|||||||||| .|.|.. |.|.||| 
ihkvqytkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfell.......gr....vpeevlvflgdyvdrgpqslevlillftlkir

YQTNYILLRGNHETRAINYAYGFREELVNrlgpADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIgNDSLAQDLLWAD
|. . .|||||||. ..|  ||| .| |       |.|.| .|.. |  .|.. |. ...||||||.|| | .|....|. .|. .. .  |  ||||||
yrdrivllrgnheiasvnkiygfyvecvt....kyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnl.drGlviDllwad

PTDgqgliAVSQtpaYpKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSI
|..      | .   . |. .|| | .| .. |.|.||||.. ||.||||.. .|.. .. .||.|.||.| | .   | .| |||. .  .|.
pdn.....kvee...w.kassrGssftfGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgisl

0049330 Metallo-dependent phosphatases 27-321 1.6e-82 270.1 In-house 27-296 (309) alignment
Range on Protein: 27-321
Range on HMM: 27-296/309.0
QLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYN-VPkddakkksgygFCnNRFVFLGDYVDRGSHSIECISLMFALKIIY
.  ....||..|.. ..  ||. ..| ..| .....||||||..||.|.|. . .|            . .|.|||||.||||..|.|.. |..|||. |
lkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfp...........pe.drlvflGDlvdrGpdslevlllllalklly

QTNYILLRGNHETRAINYAYGFREELVNRLGpadgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLfEIGNDSLAQDLLWADP
  | .|||||||.|..|..|||..|.. ..|     |.||.|.......|||...|.||||.|||.|| |..|..|.... || || .|.|  ||||.||
pdnvfllrGNHElrllnglygfgdetlrkyg....aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpl.eipldgllcdllwsdp

TDGQGLiavsqtpaYPKNIvRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRL
..            ...|. |||.|||.. ||.. .|..|..||.|.|.. ..|...|.|.||.|.||||.|.....|.|| |... .. .|.  .
lpireg........fapnp.rglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllf

0053225 Metallo-dependent phosphatases 28-317 7.3e-78 254.9 In-house 20-284 (293) alignment
Range on Protein: 28-317
Range on HMM: 20-284/293.0
LEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNV-PkddakkksgygfCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQ
  ....||..|.....  ||. ..| ..| .....|||||...||...|..   |             ..|.|||||.||||..|.|.. |..|||. | 
kllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfp............pedrlvflGDlvdrGpdslevlelllalkllyp

TNYILLRGNHETRAINYAYGFREELVNRLGpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIgNDSLAQDLLWADPT
.| .|||||||.. .|..|||..| . ..|   ..|.|. ........|||.|.|.|||..|||.|| |..|..|..|. || .  ...|  |||| ||.
dnvvllrGNHElmllnglygfgdetlrkyg...aaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplrip.legllldllwsdpd

DGQGlIAVSQtpaypknivRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLS
.  | .. |.         |||.|||.. || . .|. |..||.|.||. |.|.... |.||.|.||||.|.....|.|| |.....   .
lwsg.wlpsy.........rglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwg

subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 30-323 1.4e-84 276.4 In-house 10-281 (287) alignment
Range on Protein: 30-323
Range on HMM: 10-281/287.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNynvpkddakkKSGYGfCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
.. ........ .   |.  ..| ..  |.|||||||||..||.||.|          . |.   . ...|||||||||..|.| . |.|.||| |  . 
fsdkdilevlekieeileplpalleveapitivGdihGqlddllrifn..........avGaa.pkvqylflGdyvdrGakslevslllfslkiaypkkv

ILLRGNHETRAINYAYGFREELVNRLGpadgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGN-DSLAQDLLWADPTDG
 ||||||| ..||  |||.||| .. .    ......||.||...||   |...||||||||||.|..|...| . .|  ..   . |  |||||||.  
hllrGnhevkkinklyGfkeelkrkrq....erlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekd

QgliavsqtPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRN
.         ..  | .|..|||| .  | | .|.|.|.||||||..  ||..|..|..|.|.||||.|. |  | || ..|.   .||.  |. 
a........ktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkp

PPP_3 30-315 2.7e-82 268.8 In-house 2-263 (271) alignment
Range on Protein: 30-315
Range on HMM: 2-263/271.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKDDakkksgygfcnNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
....|| .|.. ..  |.. ..| .|| |||..||||||..||... ..  | ..           ....|||||||||..|.|.. |..|||| |... 
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspe...........tkYlFlGdyVDrGkkslEvlllLlalkikypkev

ILLRGNHETRAINYAYGFREELVNRLGpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTdgq
.|||||||.| ||  |||..|.... |   ||.|..|..|||...||| |. ||.|..|||.||....|..||.....  |. ....  |||. ...   
hLlRGnhEsrqinkvYgFkkevlkkkg...gkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerk.ievpeegklldlllssdp...

gliavSQTPAYPKNiVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGR
     ...  . .. .||....| . .... ...  .|||.|||.. .||.....|.|..|.|||| |.....| || ||.|.. .
.....ekeeglens.krGagllFgpdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealt

subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 30-318 5.6e-71 232.3 In-house 8-277 (284) alignment
Range on Protein: 30-318
Range on HMM: 8-277/284.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYN-VPKDDAKKKSgygfcnNRFVFLGDYVDRGSHSIECISLMFALKIIYQTN
... |||.|      .. ...   .|  ||.||||||||| ||. .|. |  |  . ..|.      ....||||||||| .||| |.|.||.|...  .
lkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeake......kkylflgdyvdrgpfsievitllfayklllpdk

YILLRGNHETRAINYAYGFREELVNRLGpadgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTDG
 .|||||||.| .|  ||| .| ..|      . ..| |.  |  |||...|..||.|||||||  |  |....... | ..| .  .  || ||||   
vfllrgnhesrpvnmqygfyleckkrys....ealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerp.idipdigviadltwadpeae

qgliaVsqtPAYpKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSI
     |     | |.  ||   || ..||.. .|.  ..|.|||||.. .|..||||.||.|||||| |  ..|| .| |.|...   |.
.....v...egy.kesprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasf

subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 30-323 2.5e-70 229.8 In-house 16-288 (290) alignment
Range on Protein: 30-323
Range on HMM: 16-288/290.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNynvpkddakkKSGYGfCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
.. ........ .   |.   .| ..  |..||||||||. .|.| ..          . ||   . .|.|||||||||..|.|   |.| .|| |  . 
fsdkdileilekieeileplpalleveapivivgdihgqldallryfd..........avgyp.pkvkflflgdyvdrgakslevslllfcykiryskkv

ILLRGNHETRAINYAYGFREELVNRlgpaDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIG-NDSLAQDLLWADPTDG
 |||||||.| .|  |||.|||. .     | ..| ....||| ..| . ||.||||||||||..... | .| . .|  .   .. |  ||||||||  
hllrgnhevrkvnrlygfkeelark....rgsrlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrd

QgliavSQTPAYpkNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRN
.     ..| |.  |  |..|||| . .. | .|.|...||||||..  |||.|  |.||.|.|||| |  .  | || ..|    .|||  |. 
k.....ddtial..nkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlkp

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 30-321 1.8e-69 227.4 In-house 9-312 (317) alignment
Range on Protein: 30-321
Range on HMM: 9-312/317.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYN-VP--KDDAKK-------KS----------------GYGFCNNRFVFLGD
....|||.|      .. ...   ..  ||||||||||||.||. .|. |  |  ....|.       .|                    ......||||
fkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwplssqeeksepkslllesskdvkqtvaavksvnkevtkgykkylflGd

YVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLGpadgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKN
||||| .||| ..|.||||. |  . .|||||||.|..|  ||| .|  .|      ....| |. .|  .||. .|..||||||||||  |  |. ...
yvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrys....aalyeafqlafnvlplcavvnkkilcmhGGiseelldlkqldk

IDHPLfEIGNDSLAQDLLWADPTDGQgliavsqtPAYpKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDN
.. || .| .  .  || ||||              | |.  || . || ..||.. .|.| ..|.|||||.. .|..||||.||.|||||| |  ..||
lkrpl.dipdvGvladltwadpdaev........kgy.kesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldn

HGATLKVETNGRLSIGRL
 .| |.|... ..||  |
iaavlsvdkklkisinvl

subfamily_PPP3C_pd Subfamily PPP3C 30-314 1.4e-68 224.7 In-house 41-313 (452) alignment
Range on Protein: 30-314
Range on HMM: 41-313/452.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNynvpkddakkkSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
 .... ...|. ..  ||....| ... |.|..|||||||.||.....            |    . ...|||||||||..||||.  ..|||| |....
leeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfe...........vgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstl

ILLRGNHETRAINYAYGFREELVNRLgpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHpLFEIGNDSLAQDLLWADPTDGQ
 |||||||.| .   . |.||.  .     ..||.... | |  .||| |. .. ||.|||.|| ...|.|||..|  . |. .  .  ||||.||..  
fllrGnhecrhlteyftfkeeckiky....seevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldr.fkeppasGplcdllWsdPledy

GLIAvsQTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFAD------QKLLTIFSAPRYMNETDNHGATLKVETNG
|  .  .. .. .| ||| |.... .|| .  ..  .  |.|||.   .|.. . .        |.|.|||| |..  .| .| ||.|.| 
geek..teekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennv

subfamily_PPZ_pd Subfamily PPZ 30-312 3.2e-61 200.4 In-house 25-282 (300) alignment
Range on Protein: 30-312
Range on HMM: 25-282/300.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNynvpkddakkKSGYGFCNNrFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
  .||..|.       .  . .| ..||.| ||||.|||. ||.|..           | |.   .| ..||||||||| .|.| | |... || |  |.
lknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlft..........kcgfppsan.ylflgdyvdrgkqsletillllcykikypenf

ILLRGNHETRAINYAYGFREELVNRLgpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLfEIGNDSLAQDLLWADPTDgq
.|||||||   .   ||| .|   |       ..|. | . |  .|||..|  ||.|.|||.|| ||....|. . .|  .. .  | .||||.||||  
fllrgnhecanvtrvygfydeckrrc....nikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrpt.dvpdfglindllwsdptd..

gliavsqTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVET
       ..   ..  ||.| ..|. |.    ...|. |..||| .. .|..|| |. |.|.|||| |  | || || . |  
.......ssnewednergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvse

subfamily_PPP6C_pd Subfamily PPP6C 30-313 4.1e-60 196.4 In-house 15-273 (290) alignment
Range on Protein: 30-313
Range on HMM: 15-273/290.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILnynvpkddakkKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
 ....| .| |||.  | |. ..  .| |||..|||||||.||  ..           ..|  . ....|||||.|||| .|.| ......||. |  . 
lpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelf...........rtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdri

ILLRGNHETRAINYAYGFREELVNRLGPADgkeVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTDGQ
.|||||||.| |  .||| .| .|. | |.   .|  . .||  ...| .. |..||.|||.||...||..|. |.    || ..    ||.|.|| | .
tllrgnhesrqitqvygfydeclnkygnan...awkyctkvfdlltiaaiideqvlcvhGglspdvktldqirviera.qeiphkgafcdlvwsdpedve

GlIAVSQtpaypknivRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETN
   |||.         ||   .| .  ... ..   .|||.||||.. ||.|.. |.|| |..||| |     |  . |..|..
t.wavsp.........rgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaleda

PP2Ac_SM00156 31-323 1.2e-102 335.6 In-house 2-269 (271) alignment
Range on Protein: 31-323
Range on HMM: 2-269/271.0
TKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILnynvpkddakKKSGyGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYI
.|.|...|.. |   ||....| ..|.|||.|||||||..||.|.|          .. |  ......||||||||||..|||.|.|.|||||.| ....
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrll..........elag.eppeekyvFlGdYVDRGpqsiEvillLfalkilypekvv

LLRGNHETRAINYAYGFREELVNRLgpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHpLFEIGNDSLAQDLLWADPtdgqg
|||||||.. .| .|||.||. ..     |||..|||.|.|...|||.||..||||||||.||.|..|.||....    |. ...|. ||||.||     
LLRGnHEsssvnkiygfeeevkrky....gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkr.vkekpeegllidllwsdp.....

liaVSQTPAYPKNIvRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRN
    .... . ... |||||||.|.||....|.. .|||.|||....||..||||.||.||||||.|..|..|..|.||||.| .||| .|..
...eqkekgfqpsk.rglsvvFgedavkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlke

PPP_1 31-309 8e-75 244.5 In-house 2-263 (264) alignment
Range on Protein: 31-309
Range on HMM: 2-263/264.0
TKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKDdakkksgygfcNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYI
...||..|.. ..  |.... | ..| ..|..|||||||.||... ..  | .           .....|||||||||..|.|.. |..|||. |. .  
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpsp...........etnYlFlGDyVDRGkdSvEilllLlalklkypkelf

LLRGNHETRAINYAYGFREELVnrlGPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTDgqG
|||||||.| ..  |||..|..       .||... . .||...|||.|. ||||..|||.|| |..|..|.....   |. ... ..|||..| ..   
llRGNHEsrqvtkvygFkkEvl...kkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrk.tevpeegklcdllekdvdi..l

LIAVSQTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLK
| . ...    .| .|| . .|.. .... ... ..|||.|||.. .||..|....|..|||||. |..|..|.|| .|
lsddkeqeeavansiRGagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvk

subfamily_PPP2C_pd Subfamily PPP2C 31-313 9.4e-64 208.4 In-house 18-275 (290) alignment
Range on Protein: 31-313
Range on HMM: 18-275/290.0
TKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILnynvpkddakkKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYI
..||. .|.. .   |.... . ... |||..||.|||||||. ..           | |    .  ..||||||||| .|.|...|. |||. |.    
eesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelf...........kiggkspdtnylflgdyvdrgyysvetvtllvalkvrykerit

LLRGNHETRAINYAYGFREELVNRLGPAdgkEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHpLFEIGNDSLAQDLLWADPTDGQG
.||||||.| |   ||| .| . . | |   .||. | ..| |.||..|| |.|.|.|||.||...||..|...|  | |. ..    ||||.|| | .|
ilrgnhesrqitqvygfydeclrkygna...nvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldr.lqevphegplcdllwsdpddrgg

LIAvSQtpaypknivRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETN
.   |.         ||    | .   ..  |. |..||.||||.. ||...  |... |||||| | .   |..| |... .
wgi.sp.........rgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddk

subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 31-321 1.1e-60 198.5 In-house 24-292 (297) alignment
Range on Protein: 31-321
Range on HMM: 24-292/297.0
TKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILnynvpkddakKKSGYGFCNNrFVFLGDYVDRGSHSIECISLMFALKIIYQTNYI
|.  ...|.||    .| ..|. ..  |. ..||||||| ||.|..          .. |.    | ..|||||||||  ||| | |..| |. . .|..
teervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlf..........hrggwpptan.ylflgdyvdrgrfsietivlllaykvkfpgnlf

LLRGNHETRAINYAYGFREELVNRLgpaDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISP---RLNTLEDIKNIDHPlfEIGNDSLAQDLLWADPTD
|||||||   .| .||| ||  .|    .   ..  |..|| ..||. |. .||||||||.||   .  ||. ...|...  . |...|  |||||||  
llrgnhecefvnkvygfyeecqkry...qsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiers..tegkerlvadllwadpis

GqgLiavSqtpAYPkNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRL
|  |   |    .  .  ||  . |   || . |  . . |..||||.. .|..||| .||.||||||.|  . ||  | . .. . . |.  |
g..l...s...gfm.enqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeil

subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 31-320 6.9e-57 186.0 In-house 7-271 (280) alignment
Range on Protein: 31-320
Range on HMM: 7-271/280.0
TKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNvpkddaKKksgygFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYI
|  |.| .| .|   . |.. |..   |. ..|||| |..|. |...         .       .....||||||||| . || . |.|.||| |.    
tgheiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdli......gr.....vpeeklmflgdyvdrgpqgievlillfclkiryrdriy

LLRGNHETRAINYAYGFREELVNRLGpadgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIgNDSLAQDLLWADPTD-GQ
|||||||| ..|  |||  |   . |      .|  |. .|  ||.. |. ...||||||.|| |  |. |.|| .|   . .  |  ||||.|||. |.
llrgnhetpsvnkiygfyvecqykyg....vglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepl.drgllidllwsdptnkge

GLIavsqtpaypkNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGR
| .            .||.| .| .. | ..|| | | ||.||||.. .|....| ..|.|.|| | |  .  |  | . ...| ..|. .
gwf..........hsirgisymfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqq

subfamily_PPP4C_pd Subfamily PPP4C 32-314 1e-65 214.8 In-house 18-275 (288) alignment
Range on Protein: 32-314
Range on HMM: 18-275/288.0
KSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILnynvpkddakkKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYIL
..|. .|   .   | |.. . ..  |||. |||||||.||....           | |    .....||||.|||| .|.|.. |. |||. |  .  |
eeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelf...........kvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritl

LRGNHETRAINYAYGFREELVNRLGPAdgkEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTDGQGL
.|||||.| |  .||| .| ... | |   .||.   ||| |..||... .||.|.|||.|| ..||..|. ||    |. ..    ||||.|| | .| 
irgnhesrqitqvygfydeclrkygsa...nvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrk.qevphegplcdllwsdpedaegw

iAVSqtPaypknivRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNG
 |||  |       ||   .| . .|.. ... .|.||.||||.. ||.|.  ..|.||..||| |     |  | |... . 
.avs..p.......rgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeel

subfamily_PPP5C_pd Subfamily PPP5C 32-331 1.6e-56 184.6 In-house 36-314 (322) alignment
Range on Protein: 32-331
Range on HMM: 36-314/322.0
KSELIQLIDLVTPALKEDNSLAQISP----PVTIVGDIHGQFHDLIRILNYNvpkddakkksGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQT
|   ....  ..  ||.  || .|.      .|. |||||||.||. |.. |          |.   .| ..| ||.|||||.|.|.| .....|..|  
kkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifeln..........GlpseenpylfnGdfvdrGsfsveviltllgfkllyPn

NYILLRGNHETRAINYAYGFREELVNRLgpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPR-LNTLEDIKNIDHPLFEiGNDSLAQDLLWADPT
.. | |||||.  .|  |||..|  ..      ..| . |.||| ..||| .. ||.| .|||.  .   ||.|...||    .  ...|  .|||.|| 
hfflsrGnhesdnmnklyGfegevkaky....tekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqp.peegllvellwsdpq

DGQGLIAvSQtpaypknivRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKV-ETNGRLSIGRLRNMK
. .|. . |.         ||..| |     .  .|  ...||.|.|..  ||...  | ||.|.|||| | ....|.|| ... ... .| .     ..
eanGrsp.sk.........rGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfeave

alHPNV
  ||.|
..hpdv

subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 34-318 9.2e-75 244.3 In-house 10-269 (280) alignment
Range on Protein: 34-318
Range on HMM: 10-269/280.0
ELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNvpkddakkksGYGfCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLR
.. ..|. ..  |. .... ..  ||...||.|||. ||.|...            ..   .. ..|||||||||.. .| | |..| |. |  |...||
didrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarv..........sfp.pdqnylflgdyvdrgrqqlevillllaykvrypnnflilr

GNHETRAINYAYGFREELVNRlgpaDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTDgqglia
||||.  ||  |||..|  .|      ......|.|..  .||..||. .|||||||.|..| .|.|....  | |.  ...||.||||||| .      
gnhevisinrkygfkdevkrr....yslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrp.fdsedeclamdllwadpen......

vsQTPAYPKNiVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSI
  ..  . .|  || ||.| .  |.| ...| | ||.| ||.. .|..||||.||.|.||||.|..| ||  | |.|. .  .|.
..kvtgwaen.srgvsvifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsf

subfamily_PPPLV_pd Subfamily PPPLV 37-308 7.9e-55 179.2 In-house 4-273 (290) alignment
Range on Protein: 37-308
Range on HMM: 4-273/290.0
QLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRIlnynvpkDDAKKKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNH
 | |     | ... | ..  |. ..||.||...||| .       ..   . |  ..   ..||||||||| .|.| |. ..|||..| . ..||||||
slcdvavdilaaeerllelksptyvlgdlhgnyrdliyf.......ekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnh

ETRAINYAYGFREELVNRLGPADgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFE----IGNDSLAQDLLWADPTDGQGLI
| ...  .. .. |   . |    .|||| ||.|| ..|||  . .|..|.|.||     |   |  |.. | .    |    || |.||.|| ... | 
elesvqesieykgegsfkfgdsl.eevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdls

AVS---QTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETdNHGATL
  .       . .|  || . || |.|..   || ... ..|||..  .|...  . .|||.||. ||   . |. | .
lrgelvlneGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGss.neaali

subfamily_PPG1_pd Subfamily PPG1 46-312 1.6e-58 191.4 In-house 30-284 (300) alignment
Range on Protein: 46-312
Range on HMM: 30-284/300.0
LKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKDDAkkksgygfcnnRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAY
| ..  . .|  |||.|||.||||.|.. |..   .  |.            ..||||||||| .|.| |||. .||. | .   |||||||.| |  .|
lvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdt...........nylflgdyvdrglysvetisllivlklrypsritllrgnhesrqitqvy

GFREELVNRLGPAdgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHpLFEIGNDSLAQDLLWADPTD--GQGLIAVSQTPAYPKN
||  | ... |      ||. . |.| |. ||... |.| |.|||.||   ....|| .|  . |. |.    ||||.|| .     |    .   . ..
gfyteclrkyggn..srvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldr.frevpnegaladllwsdpeennnptldhpdregqhfvv

IVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVET
  ||    . .  |.   .   .. |.||||.  ||.. . |.|| |..||| | .   |. . |... 
sqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelye

subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 49-325 3e-65 213.4 In-house 22-275 (284) alignment
Range on Protein: 49-325
Range on HMM: 22-275/284.0
DNSLAQISPPVTIVGDIHGQFHDLIRILNynvpkddakkKSGYGFCNNrFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFR
.  | ..  |. |.||||||| ||.|...          | |.    | ..||||||||| | .| | |.|| |.|.   ...||||||   ||  ||| 
qpmlievnspinicgdihgqfsdllrlfd..........kngfphran.ylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiygfy

EELVNRLgpaDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGNDSLAQDLLWADPTDGQGliavsqtPAYPKniVRGL
||   |    .   |.  |. ||. |||..|||..|||||||.|  |. . ... | .|. .   ..|| |.||.|||. |           |.   ||.
eecqrry...nkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqk.......gwnpn..srgv

SVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRNMK
| ||   |..    || | |.|||||.. .|..|||...|.|||||| |  . ||  | . |. |   |.  ||  |
syvfgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlrprk

subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 53-321 3.3e-70 229.8 In-house 3-253 (263) alignment
Range on Protein: 53-321
Range on HMM: 3-253/263.0
AQISPPVTIVGDIHGQFHDLIRILNYNvpkdDAKKKsgygfcnNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELV
 ..  |. |.|| |||. ||.||.|       |  |        ...||||||||| ||.| | |.|.||.    .  ||||||| .|||  |||. || 
lelqapinicgdthgqyndllrifnac....gaatk.......tqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelk

NRLGPADGKE-VWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGNDSLAQDLLWADPTDgqgliavsQTPAYPKNIVRGLSVV
.|.   .  | |...||.||.||||...| ..||||||||||.|..|.||. |  ||       || |||||||          ..  .  | .| .| |
krfqreevyesvynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpek........dakgfepnkiraisnv

FNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRL
| .  | | |||| | |||||||..  |. ||||..|.|.||| ||  |  |. | . |.    ||. .|
fgkkevddlckrldidlivrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvql

subfamily_PPP7C_pd Subfamily PPP7C 54-205 5e-35 113.9 In-house 61-200 (383) alignment
Range on Protein: 54-205
Range on HMM: 61-200/383.0
QISPPVTIVGDIHGQFHDLIRILNynvpkddakkKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVN
.||  ||. ||.||.. ||. ||           | |.   .| .|| ||.||||..|.| . ...|| ..| ..  | |||||   .|  |||  |. .
aiskevtvcGdlhGklddlllily..........knGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhilnlryGfikeves

RLgPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRlNTLEDIKNID
.  .  ||.. . ...|||..|||.|. |||| .||||| .   || ...|.
ky.kvhgkkilrlledvfawlplatlidekilivhGGisdk.tdlelldkie

Metallophos Calcineurin-like phosphoesterase 58-276 1.9e-40 132.3 Pfam-A 2-199 (200) alignment
Range on Protein: 58-276
Range on HMM: 2-199/200.0
PVTIVGDIHGQFHDLIrilnynVpKDDAKKKSGYGFCNNRFVFLGDYVDRGSHSIECISLM--FALKIIYQTNYILLRGNHETRAINYAYGFREELVNR-
.....||.||...||            . .| .    .. ..||||.|||| .|.|.. |.  ..||. . ....||||||| . .| ||||..|  .. 
rilvigDlHgglddle......d.lllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdl

-----------------------------LGPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIknidhplfeigndslaqdllwadp
                             |.| .|....|...|.|...||. ||. |||..||..|..... .||                        
rglangeeeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi........................

tdgqgliavsqtpaypknivrgLSVVFNEAAVHDTCKRLGIKLIVRAHQMI
                       |. |.. |. . ... |..|..|.|.  
......................gselfgpdalekllekygvdlvlrGHtHk

PPP_5_Dcr2 59-275 5.1e-61 199.1 In-house 1-198 (199) alignment
Range on Protein: 59-275
Range on HMM: 1-198/199.0
VTIVGDIHGQFHDLIRILNYNVpKDDAKkksgygfcNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLgpa
||..||.|||..||. ||  ..  | ..        ....||||||||||..|.|.. |..|||. |. ...|||||||....|  |||..| ...    
vtvcGDlHGqlddlllilfkeg.gdpse........erlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlsky...

DGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIG-NDSLAQDL-LWADPTdgqgliavSQTPAYPKNIVRGLSVVFNEAA
.||........|| ..||| |. ||.|..|||.|| ....|....|... .||  ..   .|| ||.||.        ...  .  | .|| ...|.. .
hgkkiykilsdvfdwlPlaalidekvlvvhgglspeiksiellekierk.ieipeekgekadlllwsdpr........daqegcklnseRGagllfgpdv

VHDTCKRLGIKLIVRAHQM
... ... ..|||.|.|..
tekfleknnlkliirshel

PPP_4 59-275 4.9e-60 195.9 In-house 1-196 (197) alignment
Range on Protein: 59-275
Range on HMM: 1-196/197.0
VTIVGDIHGQFHDLIRILNYNV--PKDDakkksgygfcnNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRlg
||.|||||||..||. .|  |   |...           ...||||||||||..|.|.. |..|||. |.....|||||||....|  |||..|....  
vtvvGDiHGqlddlllkllkngglpsee...........rsyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek..

paDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIG-NDSLAQDL-LWADPTdgqgliavSQTPAYPKNiVRGLSVVFNE
  .|||...|...||...||| |. ||.|..|||.|. |..|..|..|... .|.  ......|| ||.||.        ...  . .. ||| ...| .
..hgkeilkklqdvfdllplaalidekvlvvhgglsdelesldkierierk.iespleeekrkdlllwsdpr........eaqeglans.vrGagllFgp

AAVHDTCKRLGIKLIVRAHQM
 .... ... ..|||.|.|..
dvtekfleknnlkliirshel

PPP_2 59-275 1.5e-59 194.0 In-house 1-197 (198) alignment
Range on Protein: 59-275
Range on HMM: 1-197/198.0
VTIVGDIHGQFHDLIRILNYNVPKDDakkksgygfcnNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLGpa
||..||.|||..||... ..  |...           ....|||||||||..|.|.. |..|||. |... .|||||||.. .|  |||..|.... |  
vtvcGDlHGqldDLlilfknglpspe...........rkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkg..

dGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGNDSLAQDLlwadptDGQGLIAVSQTPAYPKNIVRGLSVVFNEAAVH
 ||.|..|..|||...||| |. ||.|..|||.|.....|..||.....     . .| ..|        . |   ...    .| .|| ...|.. ...
.gkkvykklqevfelLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldll......eeeklsdpkekeellansarGagllfgpdvte

DTCKRLGIKLIVRAHQM
. ...  .|||.|||..
elleknklkliiRaHev

subfamily_YNL217W_pd Subfamily YNL217W 59-159 5.6e-07 22.3 In-house 12-92 (235) alignment
Range on Protein: 59-159
Range on HMM: 12-92/235.0
VTIVGDIHGQFHDLIRILNynvpkdDA--KKKSgygfcNNRFVFLGDYVDRGSHSIECISLMfalkiiYQTNYILLRGNHETRAIN-YaygfreELVNRL
. .|||.|| . .||..|.      |.   |.      |   |..|| ...| .|.| .|..       ...   ..||||  ..  |      ..| . 
llvvGdvhgaYDelieLld......dkiggkde.....nvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvllay......kwvkkp

GPAD
  |.
kgae

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 95-322 5e-48 156.9 In-house 119-332 (339) alignment
Range on Protein: 95-322
Range on HMM: 119-332/339.0
NNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLgpaDgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPR
 .|..|||||||||  |.| . |. |||. |     |||||||.|..| .|||  |.  |    |  ...| |...|  .|..... . |.||||||| .
ykrylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyry...d.aqlyecfqnmfnvfpfcavinntimcmhggiseh

LNTLEDIKNIDHPLfEIGNDSLAQDLLWADPTDGQgliavsqtPAYpKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSA
| .....  . .|| || .  .  || ||||   .          | |   || |.||   |..   |.| .....| ||.. .|..||  ..|.|||||
ltsfnqfsvfkrpl.eipdvgvltdltwadpdpte........kgy.kpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsa

PRYMNETDNHGATLKVETNGRLSIGRLR
| |  . ||  | . .. . ..||  .|
pnycgqndntaavfsidkklkisinvfr

subfamily_PPP7C_pd Subfamily PPP7C 219-313 1.2e-14 46.8 In-house 239-324 (383) alignment
Range on Protein: 219-313
Range on HMM: 239-324/383.0
DLLWADPTDGQGLIAvsqtpaypkNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETN
|.||.||   .|  .         |..||  . |     ..  .. ..||..|.|.  |||..|  |.|.||||||  | .|  |.|| .|. ..
dilwsdpkakeGckp.........ntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkd