Gene F42G8.8 in Caenorhabditis elegans

Synonym: CELE_F42G8.8, F42G8.8

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily CelePPP-sf5
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP083_AA protein Get Run
CeleP083_AA_24-323 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 9-321 4.3e-87 284.9 In-house 3-291 (298) alignment 
Range on Protein: 9-321
Range on HMM: 3-291/298.0
VNMFLKRHLIVKSWANYRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYnvpkddakkkSGYGFCNNrFVFLGDYVDRG
|. .| ..|.|   ..      ..... .||.|..  .|. .|| .. .|... ||||||. ||.|...           .|.   .| ..|||||||||
vdellievlsvslsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdk..........agfppdan.ylflGdyvdrG

SHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLGPADgkeVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPl
....| | |..| |. |..|..|||||||. |||  ||| ||  .|        ....|..||. .||..|.|..|||||||.|..|..|......  | 
rqnlevivlllaykvkypnnffllrGnheceainrvyGfyeeckrrykslr...lyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrp.

FEIGNDSLAQDLLWADPTDGQgliavsqtPAYPKNiVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATL
|.  ..||| |||||||.. .          . .|  || |||| | .|.| ...| | |.|||||.. .|..|||..||.||||||.|... ||  |..
fdskeeslaidllwadpenav........kgwaen.srGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavm

KVETNGRLSIGRL
||. .  .|   |
kvdeklvvsfevl
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 9-313 5.8e-75 245.3 In-house 3-283 (299) alignment 
Range on Protein: 9-313
Range on HMM: 3-283/299.0
VNMFLKRHLIVKSWANYRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNvpkddakkksGYGfCNNRFVFLGDYVDRG
|. .| . | |    .       . ||..| ..   .. ...|| .. .|. ..||||||. ||.||.. .          |.   .  |.|||||||||
vdellskllnvgmsekrltksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdka..........gfp.pdvnflflgdyvdrg

SHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLgpaDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPL
   .| |.|... || |. .. .||||||  |||  ||| ||  .|        .|  |.. ||.|||. |.| .|||||||.||.|.||. ....  | 
rqnlelitlllcfkikyperffmlrgnhecpainrvygfyeecnkry...kstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpq

fEIGNDSLAQDLLWADPTDgqgliAVSQtpaYPKNiVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATL
 .  | ||  ||||||| .      | .   .  | |||.| || .  |.|...||.| |. ||||.. .|..|||..||.|||||| |  . ||  |..
.dppnpslgidllwadpdq.....svkd...wlan.vrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaim

KVETN
||. |
kvden
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 12-312 1.4e-64 211.2 In-house 3-280 (307) alignment 
Range on Protein: 12-312
Range on HMM: 3-280/307.0
FLKRHLIVKSwANYRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKddakkksgygfCNNRFVFLGDYVDRGSHS
||.||  |   |  ....||| |. ..|      .  ...| .| ||. .|||.|||| ||| ..                  .  .|| |||||||  |
fldrhyqviq.agvhkiqytkeefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrp...........petvyvftgdyvdrglls

IECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLgPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEI
.||| |.|. ||.|  | .|||||||   .|  ||| || |  . |  |.|.|  |. .|  .|...|.  ||||||||.|| |  |....|  .|. . 
lecilllftykicypenivllrgnheiarvnkkygfyeecvtsi.pkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnp

gNDSLAQDLLWADPTDgqgliAVSQTpaypKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVE
    . .|.|||||       .| .     |   ||  . |    . | |||||..||.|||||  .|.  .. .||.|||||| | |   | |. |||.
.frgivndmlwadpdp.....svfew....kassrgsgftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvd

T
 
e
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 24-324 5.8e-173 567.0 In-house 1-301 (302) alignment 
Range on Protein: 24-324
Range on HMM: 1-301/302.0
NYRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKDDAKKKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKI
.||. ||.||||..||. |. .||....||.|||||||||||||||.||.||||..|.|..||||| |.|....||||||||||||.|||||.|.||||.
kyrkkeysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkv

IYQTNYILLRGNHETRAINYAYGFREELVNRLGPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGNDSLAQDLLWA
.|.||||||||||||.|||.||||||||.||||..||||.||||||||..||||.||||||||.||||||.|..|||||.|..||.|...||||||||.|
lyptnyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfa

DPTDGQGLIAVSQTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRN
||.|.|.|.|||..|.| ||||||||||||||||.|.||||..|||||||||||||||||||.||||||||||||||.||.||.|||.|||.|||..|||
dpldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrn

M
 
k
subfamily_PPP1C_pd Subfamily PPP1C 24-318 5.6e-85 277.9 In-house 4-273 (282) alignment 
Range on Protein: 24-318
Range on HMM: 4-273/282.0
NYRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYN-VPKDDakkksgygfcnnRFVFLGDYVDRGSHSIECISLMFALK
. .... ...|. .|..    .|...  | ... ||.||||||||..||.|..... .|..             ...|||||||||..|.| | |..|.|
kgkevklkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpes............nylflGdyvdrGkqsletivlllayk

IIYQTNYILLRGNHETRAINYAYGFREELVNRLGPAdgkeVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLfEIGNDSLAQDLLW
| |..|  |||||||.  ||  ||| .|  .|..      .|..|..||...||| || |||||.|||.||.|. ||.|..|  || |. ...|. ||||
ikypenlfllrGnhesasinriyGfydeckrrysik....lWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPl.evpekgllcdllW

ADPtDGQgliavsqTPAYPKNIvRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSI
.|| | .       .  . .|  || |..|.. .|.. ...  ..|||||||.. .|..|||...|.|.|||| |..| ||.|| |.|...  .| 
sdp.dke.......vlgwsend.rGvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsf
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 25-325 6.2e-174 570.3 In-house 1-301 (302) alignment 
Range on Protein: 25-325
Range on HMM: 1-301/302.0
YRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKDDAKKKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKII
||. ||.||||..||. |. .||....||.|||||||||||||||.||.||||..|.|..||||| |.|....||||||||||||.|||||.|.||||..
yrkkeysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvl

YQTNYILLRGNHETRAINYAYGFREELVNRLGPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGNDSLAQDLLWAD
|.||||||||||||.|||.||||||||.||||..||||.||||||||..||||.||||||||.||||||.|..|||||.|..||.|...||||||||.||
yptnyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfad

PTDGQGLIAVSQTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRNM
|.|.|.|.|||..|.| ||||||||||||||||.|.||||..|||||||||||||||||||.||||||||||||||.||.||.|||.|||.|||..|||.
pldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrnk

K
|
k
0045823 Metallo-dependent phosphatases 25-322 7.6e-91 298.1 In-house 38-322 (473) alignment 
Range on Protein: 25-322
Range on HMM: 38-322/473.0
YRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYN--VPKDdakkksgygfcnnRFVFLGDYVDRGSHSIECISLMFALK
...  .....|..|.| ..  ||. ..| ..|......||||||..||.|.|. .   |.|             |.|||||.||||..|.|.. |..|||
kkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfpped.............rlvflGDlvDrGpdslevlelllalk

IIYQTNYILLRGNHETRAINYAYGFREELVNRLGPAdgkeVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLfEIGNDSLAQDLLW
| | .| .|||||||.|..|..|||..|.  ..|      ..| |.|.....|||...|.|||..|||.|| |..|..|..|. || || .|.|. ||||
ikypgnvfllrGNHElrllnglygfgdetlekyged....lyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpl.eipddgllldllw

ADPtDGQGLIAVSQTPAYPKNIvRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQK------LLTIFSAPRYMNETDNHGATLKVETNGrL
.|| . . .   .... .. .  || ...|.. ||.. .|. |..||||.|.. |||.... | |      ..|.|||| |.....| .| |... .. .
sdP.weddgdgllrlrffgnsp.rgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.i

SIGRLR
|.  ..
sfiqfd
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 25-318 9.7e-74 241.1 In-house 3-271 (281) alignment 
Range on Protein: 25-318
Range on HMM: 3-271/281.0
YRQLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNvpkddakKKsgygFCNNRFVFLGDYVDRGSHSIECISLMFALKII
  ...||| |....|  |   . |...|..| .|...|||.|.||.||.|...          .      ....|||||||||| .|.|.. |.|.||| 
ihkvqytkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfell.......gr....vpeevlvflgdyvdrgpqslevlillftlkir

YQTNYILLRGNHETRAINYAYGFREELVNrlgpADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIgNDSLAQDLLWAD
|. . .|||||||. ..|  ||| .| |       |.|.| .|.. |  .|.. |. ...||||||.|| | .|....|. .|. .. .  |  ||||||
yrdrivllrgnheiasvnkiygfyvecvt....kyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnl.drGlviDllwad

PTDgqgliAVSQtpaYpKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSI
|..      | .   . |. .|| | .| .. |.|.||||.. ||.||||.. .|.. .. .||.|.||.| | .   | .| |||. .  .|.
pdn.....kvee...w.kassrGssftfGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgisl
0049330 Metallo-dependent phosphatases 27-321 1.6e-82 270.1 In-house 27-296 (309) alignment 
Range on Protein: 27-321
Range on HMM: 27-296/309.0
QLEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYN-VPkddakkksgygFCnNRFVFLGDYVDRGSHSIECISLMFALKIIY
.  ....||..|.. ..  ||. ..| ..| .....||||||..||.|.|. . .|            . .|.|||||.||||..|.|.. |..|||. |
lkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfp...........pe.drlvflGDlvdrGpdslevlllllalklly

QTNYILLRGNHETRAINYAYGFREELVNRLGpadgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLfEIGNDSLAQDLLWADP
  | .|||||||.|..|..|||..|.. ..|     |.||.|.......|||...|.||||.|||.|| |..|..|.... || || .|.|  ||||.||
pdnvfllrGNHElrllnglygfgdetlrkyg....aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpl.eipldgllcdllwsdp

TDGQGLiavsqtpaYPKNIvRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRL
..            ...|. |||.|||.. ||.. .|..|..||.|.|.. ..|...|.|.||.|.||||.|.....|.|| |... .. .|.  .
lpireg........fapnp.rglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllf
0053225 Metallo-dependent phosphatases 28-317 7.3e-78 254.9 In-house 20-284 (293) alignment 
Range on Protein: 28-317
Range on HMM: 20-284/293.0
LEYTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNV-PkddakkksgygfCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQ
  ....||..|.....  ||. ..| ..| .....|||||...||...|..   |             ..|.|||||.||||..|.|.. |..|||. | 
kllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfp............pedrlvflGDlvdrGpdslevlelllalkllyp

TNYILLRGNHETRAINYAYGFREELVNRLGpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIgNDSLAQDLLWADPT
.| .|||||||.. .|..|||..| . ..|   ..|.|. ........|||.|.|.|||..|||.|| |..|..|..|. || .  ...|  |||| ||.
dnvvllrGNHElmllnglygfgdetlrkyg...aaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplrip.legllldllwsdpd

DGQGlIAVSQtpaypknivRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLS
.  | .. |.         |||.|||.. || . .|. |..||.|.||. |.|.... |.||.|.||||.|.....|.|| |.....   .
lwsg.wlpsy.........rglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwg
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 30-323 1.4e-84 276.4 In-house 10-281 (287) alignment 
Range on Protein: 30-323
Range on HMM: 10-281/287.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNynvpkddakkKSGYGfCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
.. ........ .   |.  ..| ..  |.|||||||||..||.||.|          . |.   . ...|||||||||..|.| . |.|.||| |  . 
fsdkdilevlekieeileplpalleveapitivGdihGqlddllrifn..........avGaa.pkvqylflGdyvdrGakslevslllfslkiaypkkv

ILLRGNHETRAINYAYGFREELVNRLGpadgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGN-DSLAQDLLWADPTDG
 ||||||| ..||  |||.||| .. .    ......||.||...||   |...||||||||||.|..|...| . .|  ..   . |  |||||||.  
hllrGnhevkkinklyGfkeelkrkrq....erlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekd

QgliavsqtPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRN
.         ..  | .|..|||| .  | | .|.|.|.||||||..  ||..|..|..|.|.||||.|. |  | || ..|.   .||.  |. 
a........ktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkp
PPP_3 30-315 2.7e-82 268.8 In-house 2-263 (271) alignment 
Range on Protein: 30-315
Range on HMM: 2-263/271.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKDDakkksgygfcnNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
....|| .|.. ..  |.. ..| .|| |||..||||||..||... ..  | ..           ....|||||||||..|.|.. |..|||| |... 
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspe...........tkYlFlGdyVDrGkkslEvlllLlalkikypkev

ILLRGNHETRAINYAYGFREELVNRLGpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTdgq
.|||||||.| ||  |||..|.... |   ||.|..|..|||...||| |. ||.|..|||.||....|..||.....  |. ....  |||. ...   
hLlRGnhEsrqinkvYgFkkevlkkkg...gkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerk.ievpeegklldlllssdp...

gliavSQTPAYPKNiVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGR
     ...  . .. .||....| . .... ...  .|||.|||.. .||.....|.|..|.|||| |.....| || ||.|.. .
.....ekeeglens.krGagllFgpdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealt
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 30-318 5.6e-71 232.3 In-house 8-277 (284) alignment 
Range on Protein: 30-318
Range on HMM: 8-277/284.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYN-VPKDDAKKKSgygfcnNRFVFLGDYVDRGSHSIECISLMFALKIIYQTN
... |||.|      .. ...   .|  ||.||||||||| ||. .|. |  |  . ..|.      ....||||||||| .||| |.|.||.|...  .
lkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeake......kkylflgdyvdrgpfsievitllfayklllpdk

YILLRGNHETRAINYAYGFREELVNRLGpadgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTDG
 .|||||||.| .|  ||| .| ..|      . ..| |.  |  |||...|..||.|||||||  |  |....... | ..| .  .  || ||||   
vfllrgnhesrpvnmqygfyleckkrys....ealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerp.idipdigviadltwadpeae

qgliaVsqtPAYpKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSI
     |     | |.  ||   || ..||.. .|.  ..|.|||||.. .|..||||.||.|||||| |  ..|| .| |.|...   |.
.....v...egy.kesprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasf
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 30-323 2.5e-70 229.8 In-house 16-288 (290) alignment 
Range on Protein: 30-323
Range on HMM: 16-288/290.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNynvpkddakkKSGYGfCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
.. ........ .   |.   .| ..  |..||||||||. .|.| ..          . ||   . .|.|||||||||..|.|   |.| .|| |  . 
fsdkdileilekieeileplpalleveapivivgdihgqldallryfd..........avgyp.pkvkflflgdyvdrgakslevslllfcykiryskkv

ILLRGNHETRAINYAYGFREELVNRlgpaDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIG-NDSLAQDLLWADPTDG
 |||||||.| .|  |||.|||. .     | ..| ....||| ..| . ||.||||||||||..... | .| . .|  .   .. |  ||||||||  
hllrgnhevrkvnrlygfkeelark....rgsrlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrd

QgliavSQTPAYpkNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRN
.     ..| |.  |  |..|||| . .. | .|.|...||||||..  |||.|  |.||.|.|||| |  .  | || ..|    .|||  |. 
k.....ddtial..nkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlkp
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 30-321 1.8e-69 227.4 In-house 9-312 (317) alignment 
Range on Protein: 30-321
Range on HMM: 9-312/317.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYN-VP--KDDAKK-------KS----------------GYGFCNNRFVFLGD
....|||.|      .. ...   ..  ||||||||||||.||. .|. |  |  ....|.       .|                    ......||||
fkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwplssqeeksepkslllesskdvkqtvaavksvnkevtkgykkylflGd

YVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLGpadgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKN
||||| .||| ..|.||||. |  . .|||||||.|..|  ||| .|  .|      ....| |. .|  .||. .|..||||||||||  |  |. ...
yvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrys....aalyeafqlafnvlplcavvnkkilcmhGGiseelldlkqldk

IDHPLfEIGNDSLAQDLLWADPTDGQgliavsqtPAYpKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDN
.. || .| .  .  || ||||              | |.  || . || ..||.. .|.| ..|.|||||.. .|..||||.||.|||||| |  ..||
lkrpl.dipdvGvladltwadpdaev........kgy.kesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldn

HGATLKVETNGRLSIGRL
 .| |.|... ..||  |
iaavlsvdkklkisinvl
subfamily_PPP3C_pd Subfamily PPP3C 30-314 1.4e-68 224.7 In-house 41-313 (452) alignment 
Range on Protein: 30-314
Range on HMM: 41-313/452.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNynvpkddakkkSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
 .... ...|. ..  ||....| ... |.|..|||||||.||.....            |    . ...|||||||||..||||.  ..|||| |....
leeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfe...........vgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstl

ILLRGNHETRAINYAYGFREELVNRLgpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHpLFEIGNDSLAQDLLWADPTDGQ
 |||||||.| .   . |.||.  .     ..||.... | |  .||| |. .. ||.|||.|| ...|.|||..|  . |. .  .  ||||.||..  
fllrGnhecrhlteyftfkeeckiky....seevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldr.fkeppasGplcdllWsdPledy

GLIAvsQTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFAD------QKLLTIFSAPRYMNETDNHGATLKVETNG
|  .  .. .. .| ||| |.... .|| .  ..  .  |.|||.   .|.. . .        |.|.|||| |..  .| .| ||.|.| 
geek..teekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennv
subfamily_PPZ_pd Subfamily PPZ 30-312 3.2e-61 200.4 In-house 25-282 (300) alignment 
Range on Protein: 30-312
Range on HMM: 25-282/300.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNynvpkddakkKSGYGFCNNrFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
  .||..|.       .  . .| ..||.| ||||.|||. ||.|..           | |.   .| ..||||||||| .|.| | |... || |  |.
lknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlft..........kcgfppsan.ylflgdyvdrgkqsletillllcykikypenf

ILLRGNHETRAINYAYGFREELVNRLgpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLfEIGNDSLAQDLLWADPTDgq
.|||||||   .   ||| .|   |       ..|. | . |  .|||..|  ||.|.|||.|| ||....|. . .|  .. .  | .||||.||||  
fllrgnhecanvtrvygfydeckrrc....nikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrpt.dvpdfglindllwsdptd..

gliavsqTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVET
       ..   ..  ||.| ..|. |.    ...|. |..||| .. .|..|| |. |.|.|||| |  | || || . |  
.......ssnewednergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvse
subfamily_PPP6C_pd Subfamily PPP6C 30-313 4.1e-60 196.4 In-house 15-273 (290) alignment 
Range on Protein: 30-313
Range on HMM: 15-273/290.0
YTKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILnynvpkddakkKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNY
 ....| .| |||.  | |. ..  .| |||..|||||||.||  ..           ..|  . ....|||||.|||| .|.| ......||. |  . 
lpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelf...........rtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdri

ILLRGNHETRAINYAYGFREELVNRLGPADgkeVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTDGQ
.|||||||.| |  .||| .| .|. | |.   .|  . .||  ...| .. |..||.|||.||...||..|. |.    || ..    ||.|.|| | .
tllrgnhesrqitqvygfydeclnkygnan...awkyctkvfdlltiaaiideqvlcvhGglspdvktldqirviera.qeiphkgafcdlvwsdpedve

GlIAVSQtpaypknivRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETN
   |||.         ||   .| .  ... ..   .|||.||||.. ||.|.. |.|| |..||| |     |  . |..|..
t.wavsp.........rgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaleda
PP2Ac_SM00156 31-323 1.2e-102 335.6 In-house 2-269 (271) alignment 
Range on Protein: 31-323
Range on HMM: 2-269/271.0
TKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILnynvpkddakKKSGyGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYI
.|.|...|.. |   ||....| ..|.|||.|||||||..||.|.|          .. |  ......||||||||||..|||.|.|.|||||.| ....
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrll..........elag.eppeekyvFlGdYVDRGpqsiEvillLfalkilypekvv

LLRGNHETRAINYAYGFREELVNRLgpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHpLFEIGNDSLAQDLLWADPtdgqg
|||||||.. .| .|||.||. ..     |||..|||.|.|...|||.||..||||||||.||.|..|.||....    |. ...|. ||||.||     
LLRGnHEsssvnkiygfeeevkrky....gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkr.vkekpeegllidllwsdp.....

liaVSQTPAYPKNIvRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRN
    .... . ... |||||||.|.||....|.. .|||.|||....||..||||.||.||||||.|..|..|..|.||||.| .||| .|..
...eqkekgfqpsk.rglsvvFgedavkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlke
PPP_1 31-309 8e-75 244.5 In-house 2-263 (264) alignment 
Range on Protein: 31-309
Range on HMM: 2-263/264.0
TKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKDdakkksgygfcNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYI
...||..|.. ..  |.... | ..| ..|..|||||||.||... ..  | .           .....|||||||||..|.|.. |..|||. |. .  
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpsp...........etnYlFlGDyVDRGkdSvEilllLlalklkypkelf

LLRGNHETRAINYAYGFREELVnrlGPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTDgqG
|||||||.| ..  |||..|..       .||... . .||...|||.|. ||||..|||.|| |..|..|.....   |. ... ..|||..| ..   
llRGNHEsrqvtkvygFkkEvl...kkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrk.tevpeegklcdllekdvdi..l

LIAVSQTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLK
| . ...    .| .|| . .|.. .... ... ..|||.|||.. .||..|....|..|||||. |..|..|.|| .|
lsddkeqeeavansiRGagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvk
subfamily_PPP2C_pd Subfamily PPP2C 31-313 9.4e-64 208.4 In-house 18-275 (290) alignment 
Range on Protein: 31-313
Range on HMM: 18-275/290.0
TKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILnynvpkddakkKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYI
..||. .|.. .   |.... . ... |||..||.|||||||. ..           | |    .  ..||||||||| .|.|...|. |||. |.    
eesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelf...........kiggkspdtnylflgdyvdrgyysvetvtllvalkvrykerit

LLRGNHETRAINYAYGFREELVNRLGPAdgkEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHpLFEIGNDSLAQDLLWADPTDGQG
.||||||.| |   ||| .| . . | |   .||. | ..| |.||..|| |.|.|.|||.||...||..|...|  | |. ..    ||||.|| | .|
ilrgnhesrqitqvygfydeclrkygna...nvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldr.lqevphegplcdllwsdpddrgg

LIAvSQtpaypknivRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETN
.   |.         ||    | .   ..  |. |..||.||||.. ||...  |... |||||| | .   |..| |... .
wgi.sp.........rgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddk
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 31-321 1.1e-60 198.5 In-house 24-292 (297) alignment 
Range on Protein: 31-321
Range on HMM: 24-292/297.0
TKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILnynvpkddakKKSGYGFCNNrFVFLGDYVDRGSHSIECISLMFALKIIYQTNYI
|.  ...|.||    .| ..|. ..  |. ..||||||| ||.|..          .. |.    | ..|||||||||  ||| | |..| |. . .|..
teervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlf..........hrggwpptan.ylflgdyvdrgrfsietivlllaykvkfpgnlf

LLRGNHETRAINYAYGFREELVNRLgpaDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISP---RLNTLEDIKNIDHPlfEIGNDSLAQDLLWADPTD
|||||||   .| .||| ||  .|    .   ..  |..|| ..||. |. .||||||||.||   .  ||. ...|...  . |...|  |||||||  
llrgnhecefvnkvygfyeecqkry...qsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiers..tegkerlvadllwadpis

GqgLiavSqtpAYPkNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRL
|  |   |    .  .  ||  . |   || . |  . . |..||||.. .|..||| .||.||||||.|  . ||  | . .. . . |.  |
g..l...s...gfm.enqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeil
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 31-320 6.9e-57 186.0 In-house 7-271 (280) alignment 
Range on Protein: 31-320
Range on HMM: 7-271/280.0
TKSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNvpkddaKKksgygFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYI
|  |.| .| .|   . |.. |..   |. ..|||| |..|. |...         .       .....||||||||| . || . |.|.||| |.    
tgheiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdli......gr.....vpeeklmflgdyvdrgpqgievlillfclkiryrdriy

LLRGNHETRAINYAYGFREELVNRLGpadgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIgNDSLAQDLLWADPTD-GQ
|||||||| ..|  |||  |   . |      .|  |. .|  ||.. |. ...||||||.|| |  |. |.|| .|   . .  |  ||||.|||. |.
llrgnhetpsvnkiygfyvecqykyg....vglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepl.drgllidllwsdptnkge

GLIavsqtpaypkNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGR
| .            .||.| .| .. | ..|| | | ||.||||.. .|....| ..|.|.|| | |  .  |  | . ...| ..|. .
gwf..........hsirgisymfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqq
subfamily_PPP4C_pd Subfamily PPP4C 32-314 1e-65 214.8 In-house 18-275 (288) alignment 
Range on Protein: 32-314
Range on HMM: 18-275/288.0
KSELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILnynvpkddakkKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYIL
..|. .|   .   | |.. . ..  |||. |||||||.||....           | |    .....||||.|||| .|.|.. |. |||. |  .  |
eeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelf...........kvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritl

LRGNHETRAINYAYGFREELVNRLGPAdgkEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTDGQGL
.|||||.| |  .||| .| ... | |   .||.   ||| |..||... .||.|.|||.|| ..||..|. ||    |. ..    ||||.|| | .| 
irgnhesrqitqvygfydeclrkygsa...nvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrk.qevphegplcdllwsdpedaegw

iAVSqtPaypknivRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNG
 |||  |       ||   .| . .|.. ... .|.||.||||.. ||.|.  ..|.||..||| |     |  | |... . 
.avs..p.......rgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeel
subfamily_PPP5C_pd Subfamily PPP5C 32-331 1.6e-56 184.6 In-house 36-314 (322) alignment 
Range on Protein: 32-331
Range on HMM: 36-314/322.0
KSELIQLIDLVTPALKEDNSLAQISP----PVTIVGDIHGQFHDLIRILNYNvpkddakkksGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQT
|   ....  ..  ||.  || .|.      .|. |||||||.||. |.. |          |.   .| ..| ||.|||||.|.|.| .....|..|  
kkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifeln..........GlpseenpylfnGdfvdrGsfsveviltllgfkllyPn

NYILLRGNHETRAINYAYGFREELVNRLgpadGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPR-LNTLEDIKNIDHPLFEiGNDSLAQDLLWADPT
.. | |||||.  .|  |||..|  ..      ..| . |.||| ..||| .. ||.| .|||.  .   ||.|...||    .  ...|  .|||.|| 
hfflsrGnhesdnmnklyGfegevkaky....tekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqp.peegllvellwsdpq

DGQGLIAvSQtpaypknivRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKV-ETNGRLSIGRLRNMK
. .|. . |.         ||..| |     .  .|  ...||.|.|..  ||...  | ||.|.|||| | ....|.|| ... ... .| .     ..
eanGrsp.sk.........rGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfeave

alHPNV
  ||.|
..hpdv
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 34-318 9.2e-75 244.3 In-house 10-269 (280) alignment 
Range on Protein: 34-318
Range on HMM: 10-269/280.0
ELIQLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNvpkddakkksGYGfCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLR
.. ..|. ..  |. .... ..  ||...||.|||. ||.|...            ..   .. ..|||||||||.. .| | |..| |. |  |...||
didrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarv..........sfp.pdqnylflgdyvdrgrqqlevillllaykvrypnnflilr

GNHETRAINYAYGFREELVNRlgpaDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIGNDSLAQDLLWADPTDgqglia
||||.  ||  |||..|  .|      ......|.|..  .||..||. .|||||||.|..| .|.|....  | |.  ...||.||||||| .      
gnhevisinrkygfkdevkrr....yslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrp.fdsedeclamdllwadpen......

vsQTPAYPKNiVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSI
  ..  . .|  || ||.| .  |.| ...| | ||.| ||.. .|..||||.||.|.||||.|..| ||  | |.|. .  .|.
..kvtgwaen.srgvsvifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsf
subfamily_PPPLV_pd Subfamily PPPLV 37-308 7.9e-55 179.2 In-house 4-273 (290) alignment 
Range on Protein: 37-308
Range on HMM: 4-273/290.0
QLIDLVTPALKEDNSLAQISPPVTIVGDIHGQFHDLIRIlnynvpkDDAKKKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNH
 | |     | ... | ..  |. ..||.||...||| .       ..   . |  ..   ..||||||||| .|.| |. ..|||..| . ..||||||
slcdvavdilaaeerllelksptyvlgdlhgnyrdliyf.......ekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnh

ETRAINYAYGFREELVNRLGPADgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFE----IGNDSLAQDLLWADPTDGQGLI
| ...  .. .. |   . |    .|||| ||.|| ..|||  . .|..|.|.||     |   |  |.. | .    |    || |.||.|| ... | 
elesvqesieykgegsfkfgdsl.eevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdls

AVS---QTPAYPKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETdNHGATL
  .       . .|  || . || |.|..   || ... ..|||..  .|...  . .|||.||. ||   . |. | .
lrgelvlneGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGss.neaali
subfamily_PPG1_pd Subfamily PPG1 46-312 1.6e-58 191.4 In-house 30-284 (300) alignment 
Range on Protein: 46-312
Range on HMM: 30-284/300.0
LKEDNSLAQISPPVTIVGDIHGQFHDLIRILNYNVPKDDAkkksgygfcnnRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAY
| ..  . .|  |||.|||.||||.|.. |..   .  |.            ..||||||||| .|.| |||. .||. | .   |||||||.| |  .|
lvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdt...........nylflgdyvdrglysvetisllivlklrypsritllrgnhesrqitqvy

GFREELVNRLGPAdgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHpLFEIGNDSLAQDLLWADPTD--GQGLIAVSQTPAYPKN
||  | ... |      ||. . |.| |. ||... |.| |.|||.||   ....|| .|  . |. |.    ||||.|| .     |    .   . ..
gfyteclrkyggn..srvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldr.frevpnegaladllwsdpeennnptldhpdregqhfvv

IVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVET
  ||    . .  |.   .   .. |.||||.  ||.. . |.|| |..||| | .   |. . |... 
sqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelye
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 49-325 3e-65 213.4 In-house 22-275 (284) alignment 
Range on Protein: 49-325
Range on HMM: 22-275/284.0
DNSLAQISPPVTIVGDIHGQFHDLIRILNynvpkddakkKSGYGFCNNrFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFR
.  | ..  |. |.||||||| ||.|...          | |.    | ..||||||||| | .| | |.|| |.|.   ...||||||   ||  ||| 
qpmlievnspinicgdihgqfsdllrlfd..........kngfphran.ylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiygfy

EELVNRLgpaDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGNDSLAQDLLWADPTDGQGliavsqtPAYPKniVRGL
||   |    .   |.  |. ||. |||..|||..|||||||.|  |. . ... | .|. .   ..|| |.||.|||. |           |.   ||.
eecqrry...nkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqk.......gwnpn..srgv

SVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRLRNMK
| ||   |..    || | |.|||||.. .|..|||...|.|||||| |  . ||  | . |. |   |.  ||  |
syvfgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlrprk
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 53-321 3.3e-70 229.8 In-house 3-253 (263) alignment 
Range on Protein: 53-321
Range on HMM: 3-253/263.0
AQISPPVTIVGDIHGQFHDLIRILNYNvpkdDAKKKsgygfcnNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELV
 ..  |. |.|| |||. ||.||.|       |  |        ...||||||||| ||.| | |.|.||.    .  ||||||| .|||  |||. || 
lelqapinicgdthgqyndllrifnac....gaatk.......tqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelk

NRLGPADGKE-VWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGNDSLAQDLLWADPTDgqgliavsQTPAYPKNIVRGLSVV
.|.   .  | |...||.||.||||...| ..||||||||||.|..|.||. |  ||       || |||||||          ..  .  | .| .| |
krfqreevyesvynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpek........dakgfepnkiraisnv

FNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETNGRLSIGRL
| .  | | |||| | |||||||..  |. ||||..|.|.||| ||  |  |. | . |.    ||. .|
fgkkevddlckrldidlivrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvql
subfamily_PPP7C_pd Subfamily PPP7C 54-205 5e-35 113.9 In-house 61-200 (383) alignment 
Range on Protein: 54-205
Range on HMM: 61-200/383.0
QISPPVTIVGDIHGQFHDLIRILNynvpkddakkKSGYGFCNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVN
.||  ||. ||.||.. ||. ||           | |.   .| .|| ||.||||..|.| . ...|| ..| ..  | |||||   .|  |||  |. .
aiskevtvcGdlhGklddlllily..........knGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhilnlryGfikeves

RLgPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRlNTLEDIKNID
.  .  ||.. . ...|||..|||.|. |||| .||||| .   || ...|.
ky.kvhgkkilrlledvfawlplatlidekilivhGGisdk.tdlelldkie
Metallophos Calcineurin-like phosphoesterase 58-276 1.9e-40 132.3 Pfam-A 2-199 (200) alignment 
Range on Protein: 58-276
Range on HMM: 2-199/200.0
PVTIVGDIHGQFHDLIrilnynVpKDDAKKKSGYGFCNNRFVFLGDYVDRGSHSIECISLM--FALKIIYQTNYILLRGNHETRAINYAYGFREELVNR-
.....||.||...||            . .| .    .. ..||||.|||| .|.|.. |.  ..||. . ....||||||| . .| ||||..|  .. 
rilvigDlHgglddle......d.lllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdl

-----------------------------LGPADGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIknidhplfeigndslaqdllwadp
                             |.| .|....|...|.|...||. ||. |||..||..|..... .||                        
rglangeeeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi........................

tdgqgliavsqtpaypknivrgLSVVFNEAAVHDTCKRLGIKLIVRAHQMI
                       |. |.. |. . ... |..|..|.|.  
......................gselfgpdalekllekygvdlvlrGHtHk
PPP_5_Dcr2 59-275 5.1e-61 199.1 In-house 1-198 (199) alignment 
Range on Protein: 59-275
Range on HMM: 1-198/199.0
VTIVGDIHGQFHDLIRILNYNVpKDDAKkksgygfcNNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLgpa
||..||.|||..||. ||  ..  | ..        ....||||||||||..|.|.. |..|||. |. ...|||||||....|  |||..| ...    
vtvcGDlHGqlddlllilfkeg.gdpse........erlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlsky...

DGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIG-NDSLAQDL-LWADPTdgqgliavSQTPAYPKNIVRGLSVVFNEAA
.||........|| ..||| |. ||.|..|||.|| ....|....|... .||  ..   .|| ||.||.        ...  .  | .|| ...|.. .
hgkkiykilsdvfdwlPlaalidekvlvvhgglspeiksiellekierk.ieipeekgekadlllwsdpr........daqegcklnseRGagllfgpdv

VHDTCKRLGIKLIVRAHQM
... ... ..|||.|.|..
tekfleknnlkliirshel
PPP_4 59-275 4.9e-60 195.9 In-house 1-196 (197) alignment 
Range on Protein: 59-275
Range on HMM: 1-196/197.0
VTIVGDIHGQFHDLIRILNYNV--PKDDakkksgygfcnNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRlg
||.|||||||..||. .|  |   |...           ...||||||||||..|.|.. |..|||. |.....|||||||....|  |||..|....  
vtvvGDiHGqlddlllkllkngglpsee...........rsyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek..

paDGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPlFEIG-NDSLAQDL-LWADPTdgqgliavSQTPAYPKNiVRGLSVVFNE
  .|||...|...||...||| |. ||.|..|||.|. |..|..|..|... .|.  ......|| ||.||.        ...  . .. ||| ...| .
..hgkeilkklqdvfdllplaalidekvlvvhgglsdelesldkierierk.iespleeekrkdlllwsdpr........eaqeglans.vrGagllFgp

AAVHDTCKRLGIKLIVRAHQM
 .... ... ..|||.|.|..
dvtekfleknnlkliirshel
PPP_2 59-275 1.5e-59 194.0 In-house 1-197 (198) alignment 
Range on Protein: 59-275
Range on HMM: 1-197/198.0
VTIVGDIHGQFHDLIRILNYNVPKDDakkksgygfcnNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLGpa
||..||.|||..||... ..  |...           ....|||||||||..|.|.. |..|||. |... .|||||||.. .|  |||..|.... |  
vtvcGDlHGqldDLlilfknglpspe...........rkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkg..

dGKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPRLNTLEDIKNIDHPLFEIGNDSLAQDLlwadptDGQGLIAVSQTPAYPKNIVRGLSVVFNEAAVH
 ||.|..|..|||...||| |. ||.|..|||.|.....|..||.....     . .| ..|        . |   ...    .| .|| ...|.. ...
.gkkvykklqevfelLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldll......eeeklsdpkekeellansarGagllfgpdvte

DTCKRLGIKLIVRAHQM
. ...  .|||.|||..
elleknklkliiRaHev
subfamily_YNL217W_pd Subfamily YNL217W 59-159 5.6e-07 22.3 In-house 12-92 (235) alignment 
Range on Protein: 59-159
Range on HMM: 12-92/235.0
VTIVGDIHGQFHDLIRILNynvpkdDA--KKKSgygfcNNRFVFLGDYVDRGSHSIECISLMfalkiiYQTNYILLRGNHETRAIN-YaygfreELVNRL
. .|||.|| . .||..|.      |.   |.      |   |..|| ...| .|.| .|..       ...   ..||||  ..  |      ..| . 
llvvGdvhgaYDelieLld......dkiggkde.....nvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvllay......kwvkkp

GPAD
  |.
kgae
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 95-322 5e-48 156.9 In-house 119-332 (339) alignment 
Range on Protein: 95-322
Range on HMM: 119-332/339.0
NNRFVFLGDYVDRGSHSIECISLMFALKIIYQTNYILLRGNHETRAINYAYGFREELVNRLgpaDgKEVWEKFNEVFAYMPLACLVGEKILCMHGGISPR
 .|..|||||||||  |.| . |. |||. |     |||||||.|..| .|||  |.  |    |  ...| |...|  .|..... . |.||||||| .
ykrylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyry...d.aqlyecfqnmfnvfpfcavinntimcmhggiseh

LNTLEDIKNIDHPLfEIGNDSLAQDLLWADPTDGQgliavsqtPAYpKNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSA
| .....  . .|| || .  .  || ||||   .          | |   || |.||   |..   |.| .....| ||.. .|..||  ..|.|||||
ltsfnqfsvfkrpl.eipdvgvltdltwadpdpte........kgy.kpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsa

PRYMNETDNHGATLKVETNGRLSIGRLR
| |  . ||  | . .. . ..||  .|
pnycgqndntaavfsidkklkisinvfr
subfamily_PPP7C_pd Subfamily PPP7C 219-313 1.2e-14 46.8 In-house 239-324 (383) alignment 
Range on Protein: 219-313
Range on HMM: 239-324/383.0
DLLWADPTDGQGLIAvsqtpaypkNIVRGLSVVFNEAAVHDTCKRLGIKLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLKVETN
|.||.||   .|  .         |..||  . |     ..  .. ..||..|.|.  |||..|  |.|.||||||  | .|  |.|| .|. ..
dilwsdpkakeGckp.........ntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkd