Gene F53B6.7 in Caenorhabditis elegans

Synonym: CELE_F53B6.7, F53B6.7

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily STS
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP095_AA protein Get Run
CeleP095_AA_99-302 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_STS_pd Subfamily STS 54-289 1.5e-64 209.7 In-house 2-245 (245) alignment 
Range on Protein: 54-289
Range on HMM: 2-245/245.0
TIVAMSHAESMGLIFPNWVRvCYRRGPmeYHPYDMNMPPKLVPR--PPLHYKFDPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLIKG
||. . |.| .  .| .|.  .  .|.  |.. |.|.| .|. |  .. .||.||||||||.|.....||.||.|||.. ..||||.....||||...||
tiyivRhgeRvdevfgkWlk.sfdegk..yerkdlnlpkelprrpdglkdyksDpPlterGviqAkllgraLleagikiehifcSPslrciqTaaailkg

LGlSYTTINIDPALLSYRQMLPTNfQEMLLSPKAFFNMGYPINIQYLPSQGFIR---AENIEDYNLRIQAFFKKNIAKI-EQKQVVVISDNVMVDLTRNE
|| ....|...|.||.. .. ... ...||||... .....|. .| |.. ...   .|..|... ||....|..|.|. |.............|.....
lg.kkikikvepgllewlkldrkp.ipellspeelkkffpqidedYkpvlslselkskeseeelyeRikkvvkeiiekvpedgniliVahaatldalsrq

HV-----ETVDDILQCIKKPTCQMNFIS--LKKGEAQIMDSPILPLTKS
..     |..|.  ..||.|.|......   ........||.||.|.||
llglspresedlkklvikspycslakleenkeerkwkltdsgilsllks
subfamily_Cele-STS-like_pd Subfamily Cele-STS-like 55-289 5e-100 324.5 In-house 2-229 (229) alignment 
Range on Protein: 55-289
Range on HMM: 2-229/229.0
IVAMSHAESMGLIFPNWVRVCYRRGpmEYHPYDMNMPPKLVPRPpLHYKFDPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLIKGLGL
.| . .|| .  .| .|..    ..   |.| |.|.| .|. |.  .||.||||||.|.|.|...||.|...||.|..||||||..||||||.|.|||||
vvvirsaervdevfgkWiksadlet..kyrpldinvPkelpkra.ksykldpPlteiGkiaskligRaLrdrgiepsvvFCSPdlrsvqtaalllkglGl

SYTTINIDPALLSYRQMlptnfQEMLLSPKAFFNMGYPINIQYLPSQGFIRAENIEDYNLRIQAFFKKNIAKIEQKQVVVISDNVMVDLTRNEHVETVDD
....|...|.||.||..     .|.||.||||...|||....|.|......||...|.. ||||.|||...|.|||...|..|||...|||.|.||.|||
kraaisvePgLleyrka.....revllppkafkklgypvdekYkPlkelsmaeslsdfvariqaafkkllskveqklilvvadnvsleltrredvesvdd

ILQCIKK-PTCQMNFISLKKGEAQIMDSPILPLTKS
.|...|| |........||||||.|.|||.|.|.||
llvllkktpalsvvivnlkkGearivdspvlllsks
0035570 Phosphoglycerate mutase-like 100-302 4.6e-18 58.0 In-house 17-216 (219) alignment 
Range on Protein: 100-302
Range on HMM: 17-216/219.0
LHYKfDPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLikglGLSyttINIDPAL----------LSYRQMLPTNFQEMLLSPKAFFNM
...  |.||||||.  ..  |. | . ||... |..|| ....|||...    ||.   . |||.|          |.. ..  .  .|. .    ... 
rlqg.dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii....glp...veidprLrEidfgdlegltldeiaekypeelaawlrdpydy

GYpiniqylpsqgfIRAENIEDYNLRIQAFFKKNiakIEQKQVVVISDNVMVDLTRNEHVETVDDILQCIKKPTCQMNFISLKKGE----------AQIM
 .             ..|...|.  |.......     ... |.|.|.. ..    .  .   .. .  .. |.. .  ..|..|.           ...
rp............pggEsladvvaRvlpaleel...edgenvlvVsHggvirallayllglpleeilrlnlpngsvtvleldggggkwvlvllndtshl

DSPILPLTKSLYLVKPFYWTDVP
. .. .|..||.||......|||
elllellllslllvealllldvp
0039931 Phosphoglycerate mutase-like 101-299 2.2e-16 52.5 In-house 18-203 (219) alignment 
Range on Protein: 101-299
Range on HMM: 18-203/219.0
HYKfDPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLikglGLSyttINIDPALL-------------SYRQMLPTNFQEMLLSPKAFF
..  |.||||||.  ..  |. | . |.... |..|| ....|||...    ||.   . |||.|               .... |  .. .| .|  . 
lqg.dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii....glp...veidprLrEidfgdlegltleeiaekypeelaawlrdpydyr

NmgypiniqylpsqgfIRAENIEDYNLRIQAFFKKNIAkieQKQVVVISDNVMVDLTRNEHVETVDDILQCIKKPTCQMNFISLKKGEAQIMDSPILPLT
                 ..|...|.  |....... .|   .. |.|.|..  .    .  .   .. .  .. |.. .  ..|..|. ..    . . .
p...............pggEsladvvaRvlpaleella...genvlvVsHggvirallayllglsleeilrlnlpngsvtvlelddggwvlvllnltshl

KSLYLVKPFYWT
..|. .... . 
ddllrlllltle
0053607 Phosphoglycerate mutase-like 101-275 5.6e-13 41.4 In-house 20-181 (191) alignment 
Range on Protein: 101-275
Range on HMM: 20-181/191.0
HYKfDPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLikglglsYTTINIDPALL----------SYRQMLPTNFQEMLLSPKAFF---
..  |.||||.|.   .  .. | . |...  |..|| ....|||...         .. .||.|           .. ..  .  .|. .  .  .   
lqg.dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii.......glpvevdprlrEidfgdwegltleelaekypeelaawlrdpldyr

NmgypiniqylpsqgfIRAENIEDYNLRIQAFFKKNIAkieQKQVVVISDNVMVDLTRNEHVETVDDILQCIKKPTCQMNFISLKKGE
                 ..|...|.  |....... .|   .. |.|.... .. .  .  .   .. |  .. |.. .  ..|..| 
p...............pggEsladvaaRvlpaleella...ggnvlvVaHggvirallayllglpleellrlnlpngsvtvlelddgg
0051064 Phosphoglycerate mutase-like 103-274 4.2e-19 61.9 In-house 25-221 (241) alignment 
Range on Protein: 103-274
Range on HMM: 25-221/241.0
KFDPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLIKGLGLSYTTINIDPALlsyRQMLPTNFQEMLLS------PKAFFNMGYPINIQ
 .|.||||.|.  ..  |. | ..||..  |..||   ..|||. . ..|||.. .. .||.|   | .    .. ..|.      |.... . .     
wtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaealglpllpvvvdprl...rEidfgalegltleeiaekfpeelvawlrdpldv

YLPSQGF--------------------IRAENIEDYNLRIQAFFKKNIAK--IEQKQVVVISDNVMVDLTRNEHVETVDDILQCIKKPTCQMNFISLKKG
. |  ..                     ..|...|.  |....... .|.   ..| |.|.| . .. . .       .. |  .. |....  . |...
rppllelldlllllldlryagllddllpggEsladvaaRvlpaleellarllldgknvlvVsHggvirallayllglpleellrlnlpngsvtvlelddd
0048955 Phosphoglycerate mutase-like 103-279 4.8e-19 61.7 In-house 22-223 (240) alignment 
Range on Protein: 103-279
Range on HMM: 22-223/240.0
KFDPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLIKGLGLSYTTINIDPALLSYrqmLPTNFQEMLLS------PKAFFNMGYPINIQ
 .|.||||.|.  ..  |. | ..||..  |..||   ..|||. . ..|||.. .. .||.|  .       .. ..|.      |.... . .     
wtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaealglpllpvvvdprlrEr...dfgalegltldeiaekfpeelvlwlrdpldv

YLPSQGF--------------------IRAENIEDYNLRIQAFFKKNIAKI--EQKQVVVISDNVMVDLTRNEHVETVDDILQCIKKPTCQMNFISLKKG
. |  ..                     ..|...|.  |..|.... .|.   ..| |.|.| . .. . .       .. .  .. |....  ..|..|
rppllelldellllldlryalldedllpggEsladvaaRvlaaleellaralkpgknvlvVsHggvirallayllglpleeilrlnipngsvtvlelddg

EAQIM
   . 
lvsln
0036777 Phosphoglycerate mutase-like 104-275 7.9e-17 54.2 In-house 25-221 (247) alignment 
Range on Protein: 104-275
Range on HMM: 25-221/247.0
FDPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLIKGLGLSYTTINIDPALL-----------------------SYRQMLPTNFQEML
.|.||||.|    .  |. | ..|...  |..|| . ..|||. . ..||||.  . .||.|                         ...  | ..  .|
lDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGalegltkaeiaekypeelvawwrdpydyrppl

LSPKAFFNMGYPINIQYLPSQGFIRAENIEDYNLRIQAFFKKNIAK--IEQKQVVVISDNVMVDLTRNEHVETVDDILQCIKKPTCQMNFISLKKGE
|..   . . . .   .|| ...  .|...|.  |....... .|.   . . |.|.| . ..    .  .   .. .  .. |.. .  . |....
lelllelllldllryallpldllpggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglsledilrlnlpngsitvleldddg
0043909 Phosphoglycerate mutase-like 104-276 2.3e-16 52.5 In-house 25-226 (249) alignment 
Range on Protein: 104-276
Range on HMM: 25-226/249.0
FDPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLIKGLGLSYTTINIDPAL-----------------------LSYRQMLPTNFQEML
.|.||||.|    .  |. | ..||..  |..||   ..|||... ..|||..  . .||.|                       | ... .....  .|
lDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileelgldklpvevdprLrErdfGalegltkaeiaekypeelvawlrrsydvlppl

LSPKAFFNMGYPINIQ----YLPSQGFIRAENIEDYNLRIQAFFKKNIAK--IEQKQVVVISDNVMVDLTRNEHVETVDDILQCIKKPTCQMNFISLKKG
|..   . . ... .     ....  . ..|...|.  |. ..... .|.   . . |.... .  .    .  .   .. .  .. |.. .  . |..|
leeldelllellldyaladldplldrppggEsladvvaRvlpaleellarllkdggnvliVaHggvlrallayllglsledilrlnlpngsitvlelddg

EA
. 
gk
0037864 Phosphoglycerate mutase-like 104-277 3.3e-16 51.8 In-house 30-203 (211) alignment 
Range on Protein: 104-277
Range on HMM: 30-203/211.0
FDPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLIKGLGLSYTTINIDPAL--LSYRQMLPTNFQEMLLSPKAFFNMGYPIN-------
.|.||||.|.   .  |. | ..|...  |..|| ....|||... ..|||.. .. .||.|  ...  .   ...|.     . . . .          
ldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiilealglpllpvevdprlrErdfgalegltleeiaekypeelvawlrdpydfrppg

IqylpsqgfiraENIEDYNLRIQAFFKKNIAKI--EQKQVVVISDNVMVDLTRNEHVETVDDILQCIKKPTCQMNFISLKKGEAQ
            |...|.  |....... .|.   . . |.|.|.. ..    .  .   .. |  .. |.. .  . |..|. .
g...........EsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglsleellrlnlpngsvtvlelddggwv
0049178 Phosphoglycerate mutase-like 104-279 3.4e-16 52.1 In-house 26-224 (243) alignment 
Range on Protein: 104-279
Range on HMM: 26-224/243.0
FDPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLIKGLGLSYTTINIDPALL--------------------SYRQMLPTNFQEMLLSP
.|.||||.|.   .  |. | ..|...  |..||    .|||. . ..|||.. .. .||.|                      . ... ..  .    .
tDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiilealglpllpvvvdprLrErdfGalegltkaeiaakypeelvawwrdpydarppa

KAFFNMGYPINIQYLPS-QGFIRAENIEDYNLRIQAFFKKNIAK--IEQKQVVVISDNVMVDLTRNEHVETVDDILQCIKKPTCQMNFISLKKGEAQIM
. ......|.....| .  ..  .|. .|.  |....... .|.   . | |.|.. . .     .  .   .. |  .. |.. .. ..|. |  .. 
lllldlllplldrlladldllpggEsladvaaRvlpaleellaellhdgktvlvVaHggvirallalllglpleellrlnlpngsvtvlelddggwvlv
0036887 Phosphoglycerate mutase-like 104-279 8.2e-16 50.7 In-house 24-193 (202) alignment 
Range on Protein: 104-279
Range on HMM: 24-193/202.0
FDPPLTERGQIVSETYGRGLLnaGIRPFEVFCSPDMKSVQTAAFLIKGLGlsyTTINIDPALL----SYRQM---------LPTNFQEMLLSPKAFFNMG
.|.||||.|.   . .|. |.  |.... |..|| ....|||... ..||    .. .||.|     .. ..          |  .. .| .|  |   |
ldvpLtelGreqaralgerla..glpfdavysSpllRaiqTaeiiaealg...lpvivdprlrEidfgalegltleeiaekypeelaawlrdpydfrppg

YpiniqylpsqgfiraENIEDYNLRIQAFFKKNIAKIEQKQVVVISDNVMVDLTRNEHVETVDDILQCIK-KPTCQMNFISLKKGEAQIM
                |...|.  |. |.... .|. ... |.|.|.. .. .  .  .   .. |  ..  |.. .  ..|..|  ...
g...............EsladvvaRvlaaleellarldggnvlvVsHggvlrallayllglsledllrlrklpngsvtvlelddggwvlv
0050036 Phosphoglycerate mutase-like 104-243 3.1e-08 25.7 In-house 23-139 (171) alignment 
Range on Protein: 104-243
Range on HMM: 23-139/171.0
FDPPLTERGQIVSETYGRGLlnagiRPFEVFCSPDMKSVQTAAFLIkglglsyTTINIDPALL--SYRQMLPTNFQEMLLSPKAffnmgypiNIQYLPSQ
 |.||||.|.   .  |. |     ..  |..|| ....|||...         .. .||.|   ..  .   ...|.                ..|.  
tdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil.......lpvivdprLrErdfGawegltldeiaakype........wlldlldl

GFIRAENIEDYNLRIQAFFKKNIakieqKQVVVISDNVMVDL
 .  .|...|.  |....... .     . |.|.. . ..  
appggEsladvlaRvlpaleell.....gnvlvvaHggvira
His_Phos_1 Histidine phosphatase superfamily (branch 1) 105-238 7e-09 28.8 Pfam-A 23-152 (158) alignment 
Range on Protein: 105-238
Range on HMM: 23-152/158.0
DPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLIKGLGlsyTTINIDPALlsyRQMLP-----T---NFQEMLL-SPKAFFN----MGY
|.||||.|.   .  |. | .|....  |..||   ..|||. | ..|.   . | ..|.|   |..           . .|..  . ... .    . .
dvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeld...ipiikeprL...rerdfgeweglpkeevkeefpeeyekwkrdkkefrp

PiniqylpsqgfiRAENIEDYNLRIQAFFKKNIA-KIEQKQVVVISDN
|            ..|. .|.  |...|... |. | ....|...| .
p............egesladvyeRvapfleelieakdkgenvlivsHg
His_Phos_1 Histidine phosphatase superfamily (branch 1) 105-238 7e-09 28.8 In-house 23-152 (158) alignment 
Range on Protein: 105-238
Range on HMM: 23-152/158.0
DPPLTERGQIVSETYGRGLLNAGIRPFEVFCSPDMKSVQTAAFLIKGLGlsyTTINIDPALlsyRQMLP-----T---NFQEMLL-SPKAFFN----MGY
|.||||.|.   .  |. | .|....  |..||   ..|||. | ..|.   . | ..|.|   |..           . .|..  . ... .    . .
dvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeld...ipiikeprL...rerdfgeweglpkeevkeefpeeyekwkrdkkefrp

PiniqylpsqgfiRAENIEDYNLRIQAFFKKNIA-KIEQKQVVVISDN
|            ..|. .|.  |...|... |. | ....|...| .
p............egesladvyeRvapfleelieakdkgenvlivsHg