Gene pdp-1 in Caenorhabditis elegans

Synonym: CELE_ZK973.3, pdp-1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PDPc
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP135_AA protein Get Run
CeleP135_AA_43-440 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPM1H_pd Subfamily PPM1H 30-217 2.2e-08 26.3 In-house 23-189 (404) alignment 
Range on Protein: 30-217
Range on HMM: 23-189/404.0
RSANVEDDAIMRVDTCQLAANNPIEDFYSAAKCLSS--RAFLFGVFDGHGGQQCSRHISTNLYPYLCASVLKKHEVVDYPSDqrlewlfsssdgHLPNAF
.|   || | ..| . .  ...  ..  .  |  ..     .||.||||.|.  .   | .|   | . . .  |..   |.            . .. .
kselneDqaaakvlllkkekkeksvtskpkekseeeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksa............eeeent

KGRETQHIAEYHKQFKKNANAYTGTVREALKLAFETCDKdlaenalpsakgVIDRHAAMVAASGSCCTLAHIR-SRHLHVANLGDAAAVLG
.  ....    .......       |  ||  || ..|.            .| |       .| |..|  .     |.||| ||. |.| 
eesskespssvseiyeekeiskeeLviGalesaflemDe............qiarereayrikGGCtalvalvllgklYvanaGDsRailv
subfamily_PDP_pd Subfamily PDP 43-440 1.3e-156 514.7 In-house 1-398 (398) alignment 
Range on Protein: 43-440
Range on HMM: 1-398/398.0
DTCQLAANNPIEDFYSAAKCLSSRAFLFGVFDGHGGQQCSRHISTNLYPYLCASVLKKHEVVDY----PSDQRLEWLFSSSDGHLPNAFKGRETQHIAEY
|..|||.|.|||| .|.||.|.|...||||||||||..|....|..|. |..||.|||......    .|...|..|...|. .| .... .......|.
dsnqLasNePiEDrrseakllesngvlfgvfDGHggaacaeavskrLlkyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslsel

HKQFKKNANAYTGTVREALKLAFETCDKDLAENALPSAKGVIDRHAAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVNPNGSVTARQLSRAHCVDN
.|.......|....|.|||| ||...|||....||...|. . |.|..||.||.|..||.|....||||| ||..|||||....||..|..||. ...||
skylqelleaevekvkealkkaFlklDkdistealkklkekslreallvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadn

ADEVHRIRIAHPASESQTVLRGGRLLGELFPLRAFGDVRYKWPLDLQKVVLEP--LGHPPPQHLFTPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLD
..||.||. .||..||.||.| |||||||.||||||||||||. .|||.|||   |.. .|....|||||...|||..|||..||.||||||||||..|.
eeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwseelqkkvlekaylkvlepkdyktPPYltaePevtshklrendkFLvlatDGLwdlls

PDTVVRLVHDHTLGTITQQPY-VPKSGTSLRQVREQLKDRARGEQKtkkpIDENCATHIIRHALGGVSGGatkQYERLIDILQVPPGRARNYRDDITVIV
...||.||..|. .. ...|. |......|.||.|.||.|.|....    .|.|.|||.|||||||.. |   ..|.. ..|..| ..||.|||||||.|
neevvslVgehlakkkekepvkveeakltlkqvveelkerkrklkr....edknaAthLirhalggneag...dkekvsallsiPeelaRmyRDDitvtV

IHFNE
..||.
vffns
PP2Cc_SM00332 44-436 6.3e-57 186.0 In-house 15-274 (274) alignment 
Range on Protein: 44-436
Range on HMM: 15-274/274.0
TCQLAANNPIEDFYSAAKCLS--SRAFLFGVFDGHGGQQCSRHISTNLYPYLCASVLKKHEVVdypsdqrlewlfsssdghlpnafkgretqhiaeyhkq
...  .....||..    .|.  ... .|||||||||..... .| .|. .|. .  || .                                       
ssmqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel.....................................

fkknanayTGTVREALKLAFETCDKDLAENALPSA--KgvidrhaamvAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVNPngsvtARQLSRAHCVDNA
           | |||| ||. .|... |..  .   .          | |||....|...  .|.|||.||  |||.  .      |.|||. | ....
........eddveealkkaflstdeeileeeqskelen..........alsGstavvallkkedlyvanvGDSravlcrngk.....avqlsvdhkpede

DEVHRIRIAHPasesqTVLRGgRLLGELFPLRAFGDVRYKWPLdlqkvvleplghpppqhLFTPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDT
||..||. |..     .| .| |. | |   |||||. .|..                   ...||..  |.| ...||..|.||.||.||||. |....
derkRikkagg.....vvekg.rvngglavsrafGdhflkknk.................klkepyitaepdvkvvtltsedeflilaSDGlwdvlsnqe

VVRLVHDHTLGTitqqpyvpksgtslrqvreqlkdrargeqktKKPIDENCATHIIRHALGGvsggatkqyerlidilqvppgraRNYRDDITVIVI
|| .|...   .                               |..  ...|......|.                         ....|.|||.|.
vvdivrkllakg...............................ktndpqeaaelldeeairr.......................ggseDniTvvvv
0034914 PP2C-like 50-440 6.6e-55 179.0 In-house 32-292 (295) alignment 
Range on Protein: 50-440
Range on HMM: 32-292/295.0
NNPIEDFYSAAKCL---SSRAFLFGVFDGHGGQQCSRHISTNLYPYLCASVLKKHEVVDYPsdqrlewlfsssdghlpnafkgretqhiaeyhkqfkkna
... ||....  .|    .  .|||||||||| ......| .|. .|.  . | .   ...                                       
rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltls.......................................

nayTGTVREALKLAFETCDKDLAENALPSakgvidrhaAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGvvnPNGsvTARQLSRAHCVDNADEVHRIR
   . ...|||. ||  .|..| | || .           .| ||.....|.||...|.|||.||  |||     ||  ...||.. | ..| .|..||.
...ledieealrkaflaadeellelallr.........pelagsGtTavvalirgnklyvanvGDSravll...rng..elvqltvdhkpvnelereril

IAHPASESqtvlrgGRLLGELFPLRAFGDVRYKWPldlqkvvleplghppPQHLFTPPYLSTSPEVFYHKLT-PNDRFLVLATDGLWEWLDPDTVVRLVH
 |..|         ||..| |   ||.||...|..               ...|...|..|  |.|....|| ..| ||.||.||||..|.....|..|.
saggavsh......grvngvlavtRalGdfdlkll...............lslllleplvsaePdvtvleltledddfllLasDGlwdvlsneeivdivr

DHTLGTITqqpyvpksgtslrqvreqlkdrargeqktkkpiDENCATHIIRHALGgvsggatkqyerlidilqvppgraRNYRDDITVIVIHFNE
..  .. .                                  |..|......||                         |..||.|||.|...|.
sllakgld.................................leeaaeeLvdlAla........................rgsrDNiTvvvvrlng
subfamily_PPM1A_pd Subfamily PPM1A 51-354 1e-25 83.7 In-house 24-252 (282) alignment 
Range on Protein: 51-354
Range on HMM: 24-252/282.0
NPIEDFYSAAKCLSSR--AFLFGVFDGHGGQQCSRHISTNLYPYLCAsvlkkhevvdypsdqrlewlfsssdghlpnafkgretqhiaeyHKQF--KKNA
.  || ......|...    .| |||||.|...... ...|   .                                             ....  ..  
vemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenile...........................................eeelkeaale

NAYTGTVREALKLAFETCDKDLAENAlPSAKGViDRHaamvaasGSCCTLAHIRSRHLHVANLGDAAAVLgvvNPNGsvTARQLSRAHCVDNADEVHRIR
.  . .|.|||. .| . |... |.   ..|.  |.        || .. . .. .|| .|||||. |||     ||  .|  |.. |  ....| .||.
asekdevkealrqgfLaldeairels.tdlkta.dks.......GsTavtvlvsekhliianlGDsRavl...crng..kaaflteDHkpsrpkEkkRie

IAHPASEsqtvlrGGRLLGELFPLRAFGDVRYKWPLDLqkvvleplghPPPQHLftppyLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHD
 |            .|. | |   ||.||  ||   ..          .... |     .|..|||.  . . .| ||||| ||.|. |. ..|| ||..
qAGGsvv......vsRvnGaLAvsRalGDyeykeeeek..........kaeeql.....vsaepevtsierseeddflvlacDGiwDvlsdeevvelvrk

HTLGTiTQ
.   . ..
rleva.de
0049733 PP2C-like 53-439 1.9e-36 118.6 In-house 18-234 (235) alignment 
Range on Protein: 53-439
Range on HMM: 18-234/235.0
IEDFYSAakclssRAFLFGVFDGHGGQQCSRHISTNLYPYLCASVLKkHEVVDypsdqrlewlfsssdghlpnafkgretqhiaeyhkqfkknanaytgt
 ||.. .        .||.|.||||| ..... | .|. .|.. .|. ..  |                                               
neDavlv......glllfavaDGhgghaagevasellvetllellle.lllld...............................................

VREALKLAFETCDKDLAENALPSAkgvidrhaaMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGVvnpNGsvTARQLSRAHCVDNADEVHRIRIAHPAS
..|||. ||..... | | || |           .| .|.....| .....|.|||.||  |.|     .|  ...||.. | . | .|. ||. |..| 
leealrkaflaaneallelalasp.........elagmgtTavvalldggklyvanvGDsrayllr...dg..klvqltedhspvnelerqriitaggav

esqtvlrggRLLGELFPLRAFGDVRYKwpldlqkvvleplghpppqhlftppylstsPEVFYHKLTPNDrFLVLATDGLWEWLDPDTVVRLVHDHTLgti
         | .| |  .||.||  .|                              |.|....|.|.| ||.||.||||..|.....|.|.....|   
.........rvpgrlaltralGdlllk..............................pdvtvlelepgd.flllasDGlwdvlsdeeivdllrsldl...

tqqpyvpksgtslrqvreqlkdrargeqktkkpidENCATHIIRHALGgvsggatkqyerlidilqvppgraRNYRDDITVIVIHFN
                                   |..| .....||                         |. ||.|||.|....
...................................eeaaerlvelala........................rggrDNiTvvvvrld
subfamily_PPM1G2_pd Subfamily PPM1G2 65-348 1.3e-27 89.5 In-house 50-247 (287) alignment 
Range on Protein: 65-348
Range on HMM: 50-247/287.0
SRAFLFGVFDGHGGQQCSRHISTNLYPYLCAsvlkkhevvdypsdqrlewlfsssdghlpnafkgretqhiaeyhkqfkkNA--NayTGTVREALKLAFE
... ||.|||||||...... ...|  .. .                                                 .   .   |.....|| || 
kslalfavfDGhGGakvakyagkklikkiak.................................................kksfk..egaleqilkdafl

TCDKDLAENalpsakgvidrHAAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGVvnpNGSvtARQLSRAHCVDNADEVHRIRiahpasESQTVLRGGR
..|..| ..           ..     .|| .. . |. ..| ||| ||. ||| .   .|.  ...||. |  ....| .||       ... .   .|
etDeellkd...........eklkdesaGstavvvlikeeklyvanaGDsravlss...kgn..vkalsfDhkPqeesekkrii......aagGfvelnr

LLGELFPLRAFGDVRYKWPLDlqkvvleplgHPPPQHLFTppylsTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHT
  |.|   ||.||  .|               .| ... |     . |.|  .||...| ||||| ||.|. |  ..|| ||. . 
vngnLalsralgDfefkknvk..........kkpeeqivt.....avPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerl
Subfamily Dicty-PPM1L-like 65-92 4e-06 18.9 In-house 35-62 (305) alignment 
Range on Protein: 65-92
Range on HMM: 35-62/305.0
SRAFLFGVFDGHGGQQCSRHISTNLYPY
   .||||||||.|.. . .   .|.  
qelslfGvfdGhnGdiaaeyvkkklvei
subfamily_PPM1D_pd Subfamily PPM1D 67-246 2.6e-16 52.6 In-house 35-165 (309) alignment 
Range on Protein: 67-246
Range on HMM: 35-165/309.0
AFLFGVFDGHGGQQCSRHISTNLYPYLcasvlKKHEVVDYPSDQRLewlfsssdghlpnafkgretqhiaeyhkqfkknanaytgtvREALKLAFETCDK
   ..|||||||.. ... . .|. ..     ||.. .   ... .                                         .||.. || .. .
vafvavfDGHGGkeAakfarehlwsvi.....kkqkkflssepedv.........................................leAireaflathe

DLAENAlpsaKGVIDRHAAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVNP-NGSVTARQLSRAHCVDNADEVHRIR
 . ..     .    ..   .. .|. ...  || ..|.||. ||.|.|||| .| . ...|..| . |  .. .|..||.
amkkkl....eeWpktksgllstaGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerie
subfamily_PPM1L_pd Subfamily PPM1L 67-347 2.3e-10 33.2 In-house 35-235 (269) alignment 
Range on Protein: 67-347
Range on HMM: 35-235/269.0
AFLFGVFDGHGGQQCSRHISTNLYPYLCASVLKKhevvdypsdqrlewlfsssdghlpN-------Afkgretqhiaeyhkqfkknanaytgtvrealkl
  .|.|||||||.  . ..   |   . . ...                         .                                         
esffavfdGhGGefaaefakdvlvkaiknkliel........................dadkentep.................................

afETCDKDLAENALPSAKGVIDRHAAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLgvVNPNGsvTARQLSRAHCVDNADEVHRIRIAHPASESQTVLr
   . .| | .. |   . ....  .    .|. . .| .. ..| |||.||.  ||  .. .|  .|  ||  |   .  | .||. |      . |  
..infsklltdeilsvdekllekakraediaGttalialvqesdlivanvGdsrGvl..ydkrG..kaiplsfdhkpqqvkerkrikkaGGfiafrGvw.

ggRLLGELFPLRAFGDvrykWPLDLQKVVLeplghPppqhlfTPPYLSTSpevfYHKLTPndRFLVLATDGLWEWLDPDTVVRLVHDH
  |. | |   ||.||    .||  ...|.     .      .|  |.       ... |  .||.||.||||. .  .  || ....
..rvaGvlatsralGd....yplkdknlvi.....a......dpdiltfd....lddhkp..eflilasdGlwdtfsneeavrfiker
PPM_PTC7_SpoIIE 107-351 3.7e-19 62.4 In-house 67-212 (230) alignment 
Range on Protein: 107-351
Range on HMM: 67-212/230.0
PsdqrlewlfsssdghlpnafkgretqhiaeyhkqfkknanaytgTVREALKLAFETCDKDLAENalpsakgvidrhaamVAASGSCCTLAHIRSRH--L
.                                            .. |.|. ... ...|| ..               .. ||.....|.|.. .  |
e............................................kpeeilrrlnlalaadlede...............psssgaTavvalidpstgkl

HVANLGDAAAVLGVVNPNgsvtarqlsrahcvdnadEVHRIrIAHPASEsqTVLRGGRLLGELFPLRAFGDVRYKWpldlqkvvleplghpppqhlfTPP
.|||.||  ..|   ..                   |..||  |. . .    ...||  |.|   .|.||. ..                      |  
yvanaGdsppllvrddgg..................ereri.vagglps..lGilpgrvfgvlavslapGdlllly.....................tDG

YLSTSPEvFYHKLTPN-DRFLVLATDGLWEWLDPDTVVRLVHDHTLGT
. . .|.   ...... |.||.||.||||. |.|. .|.|| |. .  
vveaepd.tsdgelfgkdeflilasdglwdvlspqelvdlvrdelekp
PP2C Protein phosphatase 2C 110-349 1.2e-34 113.1 Pfam-A 7-230 (255) alignment 
Range on Protein: 110-349
Range on HMM: 7-230/255.0
QRLEWLFSSSDGHLPNA-FK---G-RETQHIAEYHKQFKKNANAYTGTVRE-ALKLAFETCDK----DLAENALPS-AKGVIDRHAAM--VAASGSCCTL
.  ..  |..|.|. .. ..   |  . . .| .....   |. |...  |  ||.. ....     ..  ..  . .. ......|.     |||....
elqgarksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelksskantepsksGstavv

AHIRSRHLHVANLGDAAAVLGVVNPNGsvtaRQLSRAHCVDNADEVHRIRIAHPASESqtvlrGGRLLGELFPLRAFGDVRYKWPLdlqkvvleplghpp
| ||. .|.|||.||. |||.  . .      .|.. | ... ||..||. |.   .       ||. | |   ||.||...|                 
alirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn.....ngrvngsLavsRalGdfelkpke..............

pqhlftPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTL
      ... | .|.|  .|||..| ||.||.||||. |.....| ||...  
......eqlvsaePdvtsvklteedefliLasdGlwdvlsdqeavdlvrsels
PP2C Protein phosphatase 2C 110-349 1.2e-34 113.1 In-house 7-230 (255) alignment 
Range on Protein: 110-349
Range on HMM: 7-230/255.0
QRLEWLFSSSDGHLPNA-FK---G-RETQHIAEYHKQFKKNANAYTGTVRE-ALKLAFETCDK----DLAENALPS-AKGVIDRHAAM--VAASGSCCTL
.  ..  |..|.|. .. ..   |  . . .| .....   |. |...  |  ||.. ....     ..  ..  . .. ......|.     |||....
elqgarksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelksskantepsksGstavv

AHIRSRHLHVANLGDAAAVLGVVNPNGsvtaRQLSRAHCVDNADEVHRIRIAHPASESqtvlrGGRLLGELFPLRAFGDVRYKWPLdlqkvvleplghpp
| ||. .|.|||.||. |||.  . .      .|.. | ... ||..||. |.   .       ||. | |   ||.||...|                 
alirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn.....ngrvngsLavsRalGdfelkpke..............

pqhlftPPYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTL
      ... | .|.|  .|||..| ||.||.||||. |.....| ||...  
......eqlvsaePdvtsvklteedefliLasdGlwdvlsdqeavdlvrsels
subfamily_PPM1E_pd Subfamily PPM1E 116-279 1.1e-07 24.3 In-house 43-183 (265) alignment 
Range on Protein: 116-279
Range on HMM: 43-183/265.0
FSSSDGHLPNAFKGRETQHIAEyhkQFKKNANAY---TgtvrEALKLAFETCDKDLAENAlpsakgvidrhAAMVAASGSCCTLAHIRSRHLHVANLGDA
|.  |||         ..|. |   .  .. ..    .    |||| ||...|. . . |           .     |||    . |....|.|| |||.
favfDGHgGveaakyaaahlhe...llvrqeklkedpa....ealkeafkltDerflqka...........ereklksGstavvvliekdqlyvaWlGDs

AAVLgvVnpnGSVTARQLSRAHCVDNADEVHRIRIAHPASesqTVLRGGRLLGELFPLRAFGDVRYK
 |.|  |     ..|.|| . |  .. || .||  |        |.   |  | |   || |||..|
qall..v...rkgeavqlmkpHkPeredEkkRieeagGlv...vvigawRvnGvLsvsRaiGDvklk
PPM_PTC7 137-350 1.3e-33 109.6 In-house 39-236 (259) alignment 
Range on Protein: 137-350
Range on HMM: 39-236/259.0
EYHKQF----------------KKNANAYTG-TVREALKLAFETCDKDLAENAlpsakgvidrHAAM--VAASGSCCTLAHIRSRHLHVANLGDAAAVLG
 .....                |..   ...  . .||. .|. .| |   .           ..|.     |||....| |.. .|.|||.||. |||.
vfdghggreaakyarehleeilkerksfeeleklekalrksflaldtdeelks..........seantepstsGstAvvalitgsklyvAnvGDSravLc

VVNPNGsvtaRQLSRAHCVDNADEVHRIRIAHPASESQtvlRGGRLLGELFPLRAFGDVRYKW-PLdlqkvvleplghpppqhlfTPPYLSTSPEVFYHK
  . .      ||.. | ..| ||..||..|.   ..    . ||. | |   |||||...|  .                    .....| .|..  .|
rsgnav....kqltedHkpsnedEreRiegaggsvsnv...gngrvngvlavsRafGdfelkpket...................eeqlvsaePdisstk

LTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTLG
....| ||.||.||||. ......| ||...   
ideedefliLasdGlwdvvsdqeavdlvrselsk
subfamily_ILKAP_pd Subfamily ILKAP 143-279 2.7e-08 26.3 In-house 75-197 (293) alignment 
Range on Protein: 143-279
Range on HMM: 75-197/293.0
KKNANAYTGTVREALKLAFETCDKDLAENAlpsakgvidRHAAMVAASGSCCTLAHIRSRHLHVANLGDAAAVLGVVNPNGS-VTARQLSRAHCVDNADE
|.. .| . ... .|  .|.. |... . |         ..|  |   ||  |.  .    |.||||||. |||   ...|. ... .|.. |   . .|
ksdvsakekeikkclvdsfkktdeefLkla.........skakPvWkdGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyee

VHRIRiahpasESQTVLRGGRLLGELFPLRAFGDVRYK
 .||.       . .|.| ||.|| |   |. || |.|
rkriq......kaGgvvrdgrvlGvlevsrsiGdgrfk
PP2C_SIG_SM00331 145-437 8.6e-08 25.0 In-house 44-216 (217) alignment 
Range on Protein: 145-437
Range on HMM: 44-216/217.0
NANAYTGTVREALKLAFETCdkDLAENALPSAKGVIDRHaAMVAASGSCCTLAH--IRSRHLHVANLGDAAAVLGVvnPNGSVTARQLsrahcvdnadev
.|.|... .|.||.  ..    .  ..||  . ..|..  . .  ..  ..||.  ..|..|..||.||   .|     .. |.  .             
aAaaassqlrtalrellseg..eelsqalkrlnraiyee.keekgmfaTlllalydfssgklsyanaGdsrpyllr..dgklveilkd............

hririahpasesqtvlrggrllgelfplrafgdvrykwpldlqkVVLEPLGHPPPQHlftppylstsPEVFYHKLTPnDRFLVLATDGLWEWLDPDTvvr
                                            |   |||. |             ...   .| . . .|.|.||||.|   ...   
............................................vegaplGlepevs..........vdirelelek.gdllllytDGltearsekg...

LVHDHTLGTITQQPyvpksGTSLRQVRE----QLKDRARGEQKtkkpidencathiirhalggvsggatkqyerlidilqvppgrarnyRDDITVIVIH
.  ..  . ...       ....... .    .|  .|.|...                                              .|||||.|. 
faeerleeiledlv.....dseaqelaqkiveellelakgsng..............................................eDdiTvvvvk
subfamily_PPM1K_pd Subfamily PPM1K 152-279 7.9e-08 24.7 In-house 66-182 (263) alignment 
Range on Protein: 152-279
Range on HMM: 66-182/263.0
TVREALKLAFETCDKDLAENALPSAKGVidrhaaMVAASGSCCTLAHIRS-RHLHVANLGDAAAVLGVvnpNGSvtARQLSRAHCVDNADEVHRIRIAHP
 ... || ||| .||.|   .  |             .||.  |.. .|   .| .|.|||. |.|     ||   |..|.| |  .  .| .||. |  
dleivlknafeeldkklkrylefsvaea......ellssGttatvsllrdGtelvlaslGdsrailcr...nGk..akkltrdhdPeleeekerikaagG

ASESQTvLRGGRLLGELFPLRAFGDVRYK
  |... |   .. | |   |..||.  |
svewns.lgkplvngrlamtrslGdldlk
subfamily_PPM1G_pd Subfamily PPM1G 188-347 1.1e-16 53.9 In-house 294-428 (473) alignment 
Range on Protein: 188-347
Range on HMM: 294-428/473.0
AASGSCCTLAHIRSRHLHVANLGDAAAVLGVVnpnGsvTARQLSRAHCVDNADEVHRIRIAhpaseSQTVLRGGRLLGELFPLRAFGDVRYKWPLDLQKV
  ||.  . | .....| ||| ||. .||      |  .| .||  |  ..  | .||. |       .|   ||. | |   ||.||  ||   .|.. 
edsGttAvvaLlkekklivAnaGDsRcvlsrn...G..kAldlslDHkPeDevEleRiekA.....GGkvdedgRvnGGLnlsRAlGDhaYkkneeLplk

VLEplghpppqhlftppyLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDH
                  .|  |..  ..||..| |||||.||.|  .. . ||  |...
eqm...............isAlPDikvltlteedeFlvlAcDGiWnvmesqevvdfvrak
subfamily_TAB1_pd Subfamily TAB1 190-335 8.1e-12 37.6 In-house 129-260 (333) alignment 
Range on Protein: 190-335
Range on HMM: 129-260/333.0
SGSCCTLAHIRSRHLHVANLGDAAAVLGVVNPngSVTARQLSRAHCVDNADEVHRIriAHPASESQTVLRGGRlLGELFPLRAFGDVRYKWPLDLQKVVL
 |.   .| |   .|.||| ||. |.|   ..  |   .|||  |..|| ||. |.  ..   . ... | .| ||.  . |. || . |   .  ... 
gGttAvvalifnnkLyVaNvGdsrAllvkrke..sekvkqLsvdHttdNedEllRl..kdLGldieqikrnkr.lgskentRsiGdykvkkgykdvdils

EPLGhpppqhlftPPYLSTsPEVFYH-KLTPNDRFLVLATDGLWEWL
.  |         .| ... |.. .  ....  .||||  ||. . |
sakg.........ePviae.PdiqgaypiddityflvlmSdGvyktL
subfamily_PPM1H_pd Subfamily PPM1H 301-382 3.4e-07 22.3 In-house 300-379 (404) alignment 
Range on Protein: 301-382
Range on HMM: 300-379/404.0
FTPPYLSTSPEVFYHKLT----PNDRFLVLATDGLWEWLDPDTVVRLVHDhTLGTITqqpyvPKSGTSLRQVREQLKDRARGEQKT
.  |.||. |||    ||     .|  |.|||||||. |. ..| ..|.. .| ...     |.      .| ..|  .|||..|.
sikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivre.vlskve.....pedkkrytavaqeLvaaarGklkd
subfamily_PPM1E_pd Subfamily PPM1E 304-353 1.2e-07 24.2 In-house 184-233 (265) alignment 
Range on Protein: 304-353
Range on HMM: 184-233/265.0
PYLSTSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHTLGTIT
||.|. ..|   .|. .. .|.||.||||. .....||.||...   . .
pyvsgeadvaeveldgseeylilacDGlwDvvneeevvklveefladgae
subfamily_ILKAP_pd Subfamily ILKAP 307-347 1.3e-08 27.3 In-house 202-242 (293) alignment 
Range on Protein: 307-347
Range on HMM: 202-242/293.0
STSPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDH
.. |.|   .||.||.|.||| ||||. .. | ||. . . 
istPdvkkceLtendlfvvlaCdGLwkvfsadevvkfilkv
subfamily_PPM1D_pd Subfamily PPM1D 307-353 3.4e-08 25.9 In-house 223-270 (309) alignment 
Range on Protein: 307-353
Range on HMM: 223-270/309.0
STSPEVFYHKLTPNDR-FLVLATDGLWEWLDPDTVVRLVHDHTLGTIT
| .|.|  ..|.||.. |..||.||||. | |...|..|...   ...
sPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkel
subfamily_PP2D1_pd Subfamily PP2D1 309-348 2.4e-06 19.5 In-house 267-306 (492) alignment 
Range on Protein: 309-348
Range on HMM: 267-306/492.0
SPEVFYHKLTPNDRFLVLATDGLWEWLDPDTVVRLVHDHT
 |..   ||. .. |||||. |||| |. . |. ||..  
ePkttsvkldeaaqflvlAsnGlWevlseeevlsLvkqtl
PPM_PTC7_SpoIIE_motif 317-437 8.9e-06 19.3 In-house 9-79 (81) alignment 
Range on Protein: 317-437
Range on HMM: 9-79/81.0
LTPNDRfLVLATDGLW-------EWLDPDTVVRLVHDHtlgtiTQQPyvpkSGTSLRQVREQLKDrargeqktkkpidencathiirhalggvsggatkq
| | |. |.|.||||.       |........||....     ....        .........                                    
Lkpgdv.llLyTDGltEardsdgelfgkeellrladra.....egks....lqeladklvdevle...................................

yerlidilqvppgrA--RNYRDDITVIVIH
              .  .. .||||..|..
..............ngsgereDDitllvlr
PPM_PTC7_motif 325-347 3.2e-06 20.5 In-house 1-23 (51) alignment 
Range on Protein: 325-347
Range on HMM: 1-23/51.0
VLATDGLWEWLDPDTVVRLVHDH
.||.||||. |.....| ||.|.
iLAsDGLWDvlsdqeavdlvrdq