Gene pph-6 in Caenorhabditis elegans

Synonym: CELE_C34C12.3, pph-6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP6C
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP155_AA protein Get Run
CeleP155_AA_23-316 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0045823 Metallo-dependent phosphatases 24-316 5.3e-111 364.5 In-house 22-326 (473) alignment 
Range on Protein: 24-316
Range on HMM: 22-326/473.0
FIGSRKIEPEQWITWASECKYLPESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLF
||   .. ....| .  ....|||.|.. |.   .. |. | |....| .....||||||..|||.|..  |  |....||.||.||||..|||.. ||.
fillglldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelll

CLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYgHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWS
.| .|||....|||||||.| .  .|||.||.  || . .. . |..... ||. |.|.. .|.||||||||....| .. ..| .|.|. |.|.|..||
alkikypgnvfllrGNHElrllnglygfgdetleky.gedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllws

DPDDDVED-------WVISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEK------LATVWSAPNYCYRCGNAAAVFEIDGNNRSTKY
||..|  |       .. |.||||..||....|||| .|.| |..|.|. |.||....|. |      ..||.||||||.|.|| ||| .||.. .| . 
dPweddgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedlisfiq

FNAVPD
|...|.
fdpsph
subfamily_PPP6C_pd Subfamily PPP6C 32-319 2.8e-160 525.1 In-house 2-289 (290) alignment 
Range on Protein: 32-319
Range on HMM: 2-289/290.0
PEQWITWASECKYLPESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPN
 ..||..|..||||||.|...||....|.|. |.||.|||||||.|||||||||||.|||.|||.||.|.|||.||.||||.|||||.|.|..| .|||.
ldkwielakkckylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypd

QITLLRGNHESRRISNVYGFYDECQNKYGHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPdDDVED
.|||||||||||.|..||||||||.||||..|..|...||||.|.|.|.|||.|||||||||||..|.|......||||.|.||..||..|||| .|||.
ritllrgnhesrqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdp.edvet

WVISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNN-RSTKYFNAVPDGSR
|..|.||||..||.|||.||...|.|.|.||.||||.||.||||.|||.|||||||||||||| |...... .. |..|.|.||||  |
wavsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklfkavpdeer
0053225 Metallo-dependent phosphatases 32-305 6.2e-98 320.7 In-house 9-281 (293) alignment 
Range on Protein: 32-305
Range on HMM: 9-281/293.0
PEQWITWASECKYLPESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPN
 ...| .   .|.|.|.... |. . .. |. | |....| .....|||||...|||.|..  | .|....||.||.||||..|||...||..| |.||.
ldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkllypd

QITLLRGNHESRRISNVYGFYDECQNKYGHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDdDVED
...|||||||.. .  .|||.||.  |||. .. . ...... ||. |||....|.||||||||. ..|..  ..| ...|. |.|.|..||||| ....
nvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpd.lwsg

WVISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNN
|..|.||.|.|||. ....|| .|.| |..|.||.|..|....|..|| ||.|||||..|.||..|| ..|.. 
wlpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldegl
subfamily_PPP2C_pd Subfamily PPP2C 33-307 1.1e-125 411.7 In-house 5-278 (290) alignment 
Range on Protein: 33-307
Range on HMM: 5-278/290.0
EQWITWASECKYLPESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQ
...|   .||| | ||.  .||    . || |.|| .|..|||.|||.||||.||||||| || .|.|.|.|.|||||||.||.|||||| .| ..|...
dklieklkeckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvryker

ITLLRGNHESRRISNVYGFYDECQNKYGHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDdDVEDW
||.||||||||.|..||||||||  |||  || |.| ..||.||. ||.|| ..|.|||||| | |.| .  ||| ||||..|||||..||||| | . |
itilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpd.drggw

VISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNNRS
.||.||||. || ...|.|  .|.|.|. |.|||| ||..........|..||||||||||| ||..|.| . . 
gisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklky
0049330 Metallo-dependent phosphatases 33-306 4.1e-103 337.6 In-house 18-290 (309) alignment 
Range on Protein: 33-306
Range on HMM: 18-290/309.0
EQWITWASECKYLPESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQ
...| .   .|.|.|.... |.   .. |  | |....| .....||||||..|||.|..  | .|....||.||.||||..|||...||..| |.||..
dllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalkllypdn

ITLLRGNHESRRISNVYGFYDECQNKYGhGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDW
..|||||||.| .  .|||.||.. |||  .. . |..... ||. |.|....||||||||||. ..|..  |.| .|.|. |.|||..||||....|..
vfllrGNHElrllnglygfgdetlrkyg.aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpiregf

VISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNNR
. ..||.|.|||. ..|.||  |.|.|..|.|..|..|....|..|| ||.||||||.|.||..|| |||..  
apnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlv
subfamily_PPP4C_pd Subfamily PPP4C 36-313 4.2e-126 413.0 In-house 7-284 (288) alignment 
Range on Protein: 36-313
Range on HMM: 7-284/288.0
ITWASECKYLPESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITL
|    .|. . |..  ||||   . |  |.||  | ||||.|||||||||||||||| || ||.|.|.|.||.||||.||.||  || .| ..||..|||
ieklrrcelikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritl

LRGNHESRRISNVYGFYDECQNKYGHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDdVEDWVIS
.|||||||.|..|||||||| .|||  || .. ..||| |...|.||....||||||||.|.|.| .  .|| ||||..|||||..||||.| .| | .|
irgnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdped.aegwavs

QRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNNR-STKYFNA
 ||||..||..|.|.|  .||..|.||.|||| ||.|..||||. |||||||||||||| ||..|.| . .   | |.|
prgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifea
subfamily_PPG1_pd Subfamily PPG1 40-314 2.9e-110 361.2 In-house 9-293 (300) alignment 
Range on Protein: 40-314
Range on HMM: 9-293/300.0
SECKYLPESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGN
  .. |||.   .|.  | . |  |.||. . ||||. ||.||||||.||.|| || ||.|.|.|.|||||||.||.||..|| .| |.|| .|||||||
qkaellpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgn

HESRRISNVYGFYDECQNKY-GHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPD---------DDV
||||.|..||||| || .|| |  .| |.. ..|| | . |.|||.. ||||||||....|| . .||| .||||.| |.|..||||.          | 
hesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdr

ED--WVISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIdgNNRSTKYFNAV
|   .|.||||||. .| .|.|.|| |||.  . |.|||. ||.. .|..||.|||||||||||||| |.. |.  ...  .|||. 
egqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilel..yekderyfnvy
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 41-304 2.8e-88 288.8 In-house 20-283 (298) alignment 
Range on Protein: 41-304
Range on HMM: 20-283/298.0
ECKYLPESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNH
 .| . |.|   |...  . ..  . .| | .|...|||||||. ||| ||. .|  |.. |.|.|||||||...||...||..  .||||.. ||||||
ltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnffllrGnh

ESRRISNVYGFYDECQNKYGHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAG
|   | .|||||.||...| . .... | .||..||. ||| . .||.|||||. ....|.|  | |... ...    |..|.||.. |..|  ..||..
eceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadpenavkgwaensrGvs

FVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGN
.|||..| ...| . |. |..|.||.| .|.... . || |..|||.|| .  |.||| ..| .
vvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdek
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 43-303 6.8e-69 225.4 In-house 21-283 (297) alignment 
Range on Protein: 43-303
Range on HMM: 21-283/297.0
KYLPESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHES
| . |   . |    .| .  . ..| | .|. .|||||||| ||| ||. ||  | ..|.|.|||||||..|.||. ||..  .|.| .. ||||||| 
kviteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhec

RRISNVYGFYDECQNKYGHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSP---DIRTIDSLMLLDRAQEVpNKGPLCDIMWSDPDDDVEDWVISQRGA
  . .|||||.|||..|    ..  |  ||. ||.  || . .||.||||||   .  |.|.|  ..|..|  ... ..|..|.||   .  ..  ||||
efvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsgfmenqrga

GFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDG
|  ||     .   . .| |.||.||.|..|....   || |..||| || .  |.||..  | 
gcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscde
PPP_3 45-307 6e-110 359.5 In-house 2-264 (271) alignment 
Range on Protein: 45-307
Range on HMM: 2-264/271.0
LPESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRR
|.|.... |. .| . |. |.|.| .|.|||.|||||||..|||||||.||..|.|||.|.|||||||..|||...||..| .|||....|||||||||.
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq

ISNVYGFYDECQNKYGHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAGFVFG
|..||||..|...|.|. .|.| ...||..||..|||||.||.|||||||.|...|..  |.| .|||..|.|.| ..|..... | .  |.||||..||
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFg

AKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNNRS
..|||||| .|.|.|..|.|.|..||.......|. ||.||||||.|..||.|..... ...|
pdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealts
subfamily_PPP1C_pd Subfamily PPP1C 45-304 2.4e-98 321.8 In-house 10-268 (282) alignment 
Range on Protein: 45-304
Range on HMM: 10-268/282.0
LPESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRR
| |..  ||...  . |  .. .. .. ||.|.||||||..||| ||.|.|. |...|.|.|||||||. ||||..||... .|||... ||||||||  
lkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesas

ISNVYGFYDECQNKYGHGnVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAGFVFG
|...|||||||...|..  . | | .||..||. ||.|| .|||||||||... .. .  . |  |||.|| |||..|||||..|..|  ..||  |.||
inriyGfydeckrrysik.lWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsftfg

AKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGN
..| |.||..|||.|..|.||.|..|.... ...| ||.|||||| . .||.||...| .
kdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdee
subfamily_PPP3C_pd Subfamily PPP3C 46-315 4.4e-82 269.2 In-house 42-323 (452) alignment 
Range on Protein: 46-315
Range on HMM: 42-323/452.0
PESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRI
 |..|. .  .  . |. | ... |..|.|..|||||||||||.||. ||   .|||.|.||||||| .|.|.|  |..| ..||... |||||||.| .
eeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecrhl

SNVYGFYDECQNKYGHgNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWV-------ISQRG
.. . | .||. ||.. .|.. ... ||.||. ||...  |||||||||.|...|..  ||| .|.|..|||||..|||| .| ..          | ||
teyftfkeeckikyse.evydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfvpnsvrG

AGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFN------EKLATVWSAPNYCYRCGNAAAVFEIDGNNRSTKYFNAVP
  .... | . ||| .|||  . |.|.  |.|..   .        | |..|||||.    | |||.... |.   . ||..|
csyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennvmnirqfnssp
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 46-305 3.3e-75 246.2 In-house 9-273 (284) alignment 
Range on Protein: 46-305
Range on HMM: 9-273/284.0
PESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTV------PNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGN
 | . . ||    . .  |   . . .||.|.||||||| ||| |..  |         ..||.|.||||||| .|.| .||||.. |..|....|||||
kekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrgn

HESRRISNVYGFYDECQNKYGHgNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGA
|||| .   |||| ||...| . .... |   | ..|. |.... ..|.|||.| |.  .. |  |.|  ..|. | ..|. |.||. .|| .  |.|||
hesrpvnmqygfyleckkryse.alyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegykesprga

GFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNN
| |||||  .||| . .| |. |.||.| .|.... . || |..||| || .  |.|||...| . 
gkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeel
PP2Ac_SM00156 47-306 5.7e-108 353.1 In-house 3-261 (271) alignment 
Range on Protein: 47-306
Range on HMM: 3-261/271.0
ESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRIS
......|. . .. |. |.|.| ||.|||..||||||..|||.|....|..|..||||.|||||||..|.|...|||.|...||....||||||||... 
keevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssvn

NVYGFYDECQNKYgHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAGFVFGAK
..|||..|...|| . .....| ..|..||..||.|...||.||||||.....|..  |.|..| |..|.|.|..||||....... .|.||...|||..
kiygfeeevkrky.gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFged

VTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNNR
...||| .|.|.|..|.|..||||.......|| |..||||||....|.|||.... | .
avkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlk
PPP_1 47-300 2.3e-103 338.1 In-house 3-263 (264) alignment 
Range on Protein: 47-300
Range on HMM: 3-263/264.0
ESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRIS
|. ...|. .| . |. | |.. ||...|.||||||||.|||.|||.||..|.|.|.|.|||||||..|.|...||..| ||||....|||||||||.. 
eeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqvt

NVYGFYDECQNKYGHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIM-------WSDPDDDVEDWVISQRGA
.||||..|...|..  ...| ...||||||..|||||..|.|||||||.....|.   ..| .|||..|.||| .       .||.... | .  |.|||
kvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRGa

GFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFE
|..||..|||.|| .|.|.|..|.|....||.......|. |..||.||.....|..|. .
gylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvk
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 47-305 1.6e-78 256.9 In-house 26-284 (299) alignment 
Range on Protein: 47-305
Range on HMM: 26-284/299.0
ESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRIS
| . . |||   . .  .| .. | .|. .|||||||. ||| .|.  |  |.....|.|||||||   ||..|||.|  .|||... .||||||   | 
eqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhecpain

NVYGFYDECQNKYGHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAGFVFGAK
 |||||.||...|    .   | . |...|.  ||   .||.|||||| ..|.| |  | | |. ||     |..|.|||. | ||    ||  .||| .
rvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqsvkdwlanvrgvsyvfgqd

VTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNN
| .. . . |. |..|.||.|..|.... . || |..||| || .  |.||....| | 
vvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenl
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 47-303 6.6e-75 244.8 In-house 8-263 (280) alignment 
Range on Protein: 47-303
Range on HMM: 8-263/280.0
ESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRIS
| |  ..  .  . |. .| .| | .||..|||.|||. ||| ||.  .  |...|.|.|||||||.. || . ||..  ..|||.. .||||||  .| 
eadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevisin

NVYGFYDECQNKYgHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAGFVFGAK
. |||.||....| . .... | ...| ||. ||.   .||.|||||......| |  | |  . ...    |..|.||...|  |  ..||.  .|||.
rkygfkdevkrry.slalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvsvifgan

VTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDG
|  ..    |. |..| ||.|..|.... . || ||.|||.|.    |.|||  .| 
vvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivde
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 47-306 2.2e-55 181.0 In-house 8-291 (302) alignment 
Range on Protein: 47-306
Range on HMM: 8-291/302.0
ESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFK-----------TGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITL
.|. ..|. ..|. |. | ... .|.|||| ||||||| ||. ...           .  .  . |.||.|||||||. |.| ..|.|.| . ||..  |
ksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyil

LRGNHESRRISNVYGFYDECQNKYGHGN---VHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRA-QEVPNKGPLCDIMWSDPDDDVED
||||||.. |   ||| .| .|..|. .   ... | .||  .|. ||. | .||||||.|| .......  ..|  .|| .     |....|| |    
lrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqll

WVIS---------QRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNNR
 ..|          ||  .||     ...  . .|.|. |.|| . ||||.. ..|| |..|||.|     |  ||...|.| .
aavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngk
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 47-306 3.1e-55 180.5 In-house 9-292 (302) alignment 
Range on Protein: 47-306
Range on HMM: 9-292/302.0
ESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFK-----------TGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITL
.|. ..|. ..|. |. | ... .|.|||| ||||||| ||. ...           .  .  . |.||.|||||||. |.| ..|.|.| . ||..  |
ksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyil

LRGNHESRRISNVYGFYDECQNKYGHGN---VHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRA-QEVPNKGPLCDIMWSDPDDDVED
||||||.. |   ||| .| .|..|. .   ... | .||  .|. ||. | .||||||.|| .......  ..|  .|| .     |....|| |    
lrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqll

WVIS---------QRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNNR
 ..|          ||  .||     ...  . .|.|. |.|| . ||||.. ..|| |..|||.|     |  ||...|.| .
aavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngk
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 47-95 1.3e-07 24.0 In-house 11-59 (317) alignment 
Range on Protein: 47-95
Range on HMM: 11-59/317.0
ESDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGG
|.. . ||    . .  |   . . .||||.||||||| ||| |..  |
ekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG
subfamily_PPZ_pd Subfamily PPZ 48-301 7.2e-69 225.6 In-house 28-280 (300) alignment 
Range on Protein: 48-301
Range on HMM: 28-280/300.0
SDAVALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISN
|. . .|    . .  . ... .| .| | ||.|||. ||| ||   |  | ..|.|.|||||||. ||||. ||.|  .|||... |||||||   .. 
seilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnhecanvtr

VYGFYDECQNKYgHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAGFVFGAKV
||||||||. .    .. | |   |. ||. |..   ..|||||||| . ..| .  . |  .||. | . |..|||| |  ..|   .||  ...    
vygfydeckrrc.nikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptdssnewednergvsycynkva

TEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEI
 ..|| .  . |.||.| .|..|.... .  | ||.||||||    |  ||. .
inkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsv
subfamily_PPPLV_pd Subfamily PPPLV 52-298 4.2e-53 173.5 In-house 4-273 (290) alignment 
Range on Protein: 52-298
Range on HMM: 4-273/290.0
ALCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLL----ELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISN
.||   .| |  | ..... ||. . ||.||.. ||      |..||  .  ....|.|||||||..|.| .. |. | . || .. ||||||| . . .
slcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvqe

VYGFYDECQNKYGHGNVHKW--FCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSL----MLLDRAQEVPNKGPL-CDIMWSDPDDDVEDWVI------
 . .. |.. |.|.   . |  | .|||.||. | ||. |.|||.|.   | |   .     .|.| ..  .  ||  ||.||||..| .. .       
sieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvln

------SQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAV
      ..|| | ||...  | || .|.|| . |.|.  ..|...  . .| ||.|. .||    .|| .
eGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssneaali
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 53-304 7.4e-68 222.0 In-house 11-263 (284) alignment 
Range on Protein: 53-304
Range on HMM: 11-263/284.0
LCATLIDRLSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFY
|    .. .  .  .. | ||. ||||||||| ||| ||   |    ..|.|.|||||||.. |||. |||.  . .||.. .||||||   | ..||||
llfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiygfy

DECQNKYGHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPL-CDIMWSDPDDDVEDWVISQRGAGFVFGAKVTEEF
.||| .| .  |.. |  || |.|. ||. . .||.|||.|  .. .  |  . |  . |.   |  ||.|||| .  . |    ||  .|||.    ..
eecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgsdalrkl

LMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGN
|   .. |. |.||.|..|.... | .| |..||| || .  |||||. .. |
ldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnkn
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 61-303 2.2e-61 200.7 In-house 36-280 (307) alignment 
Range on Protein: 61-303
Range on HMM: 36-280/307.0
LSLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYG
.| |  .| .  |. . ||.|||| ||...|   |  |.| ||| |||||||  |||.. |||.  . ||..| |||||||  |... ||||.||     
fssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnkkygfyeecvtsip

HG--NVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAGFVFGAKVTEEFLMNNDLS
.   ..   | ..|. ||| |||   .||.|||||| .  .| |    .    | .| . |..|.|||  | .|  | ||.|| ||..| ..      . 
kcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsgftfgtnviddvckrlgve

LLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDG
|. |.||.. .|.  .   || |..||| ||    || .|. .| 
liirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvde
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 62-305 2.4e-77 252.9 In-house 25-267 (281) alignment 
Range on Protein: 62-305
Range on HMM: 25-267/281.0
SLEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYGH
| | ..| . .|... ||.|.|| || .||.  | ||....||.|||||||  |||.. |||.| ..|...| |||||||  .. ..|||| ||. ||| 
seekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasvnkiygfyvecvtkyGe

GnVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAGFVFGAKVTEEFLMNNDLSLLC
. .   | . |. ||| |||.. |||.||||||.. ..| |    .  . ...| . |..|.|||..||.|  | ||..|.|| .| ..   . .. |. 
e.lwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssftfGknvvddvckrlevelii

RSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNN
|.||.| .|.. .   || ||.|.||||    |||||  .| . 
rahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetl
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 63-305 6.1e-68 222.3 In-house 24-265 (280) alignment 
Range on Protein: 63-305
Range on HMM: 24-265/280.0
LEANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYGHG
 |.|..   .|. . |||| |. |.  ||   | ||. | .|.|||||||   .| . ||||| ..| ..| |||||||.  . ..|||| ||| ||| |
eesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnkiygfyvecqykygvg

NVHKwFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAGFVFGAKVTEEFLMNNDLSLLCR
     |  .|. .|. .|| . |||.||||||..  .|..  . |  |  ..| | |..|||| .  | |. | ||  ..||  | |.   . .. |. |
lwwd.fqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisymfgkgvveqacksleidliir

SHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNN
.||.|..|.. |   .| ||.| |||| .  |||||  .. | 
ahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanl
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 64-302 1.6e-73 240.1 In-house 29-269 (287) alignment 
Range on Protein: 64-302
Range on HMM: 29-269/287.0
EANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYGhGN
   .. | .|.||.||||||. ||| .|.  |. |...|.|.|||||||  ||| . |||.| ..||... ||||||| ..| ..|||..| ..|.. ..
lpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevkkinklyGfkeelkrkrq.er

VHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQE--VPNKGPLCDIMWSDPDDDVEDWVI-SQRGAGFVFGAKVTEEFLMNNDLSLL
..| | .||. ||. | ... .||.|||.||.....|||  | . .     ..|   |..|.||. | .   .  .|.   ||| |. ...| . |..|.
lykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllkkldidli

CRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEID
 |.|....||....|...| ||.||| |. .  | .||  ..
vrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvs
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 65-302 1.1e-66 217.8 In-house 36-276 (290) alignment 
Range on Protein: 65-302
Range on HMM: 36-276/290.0
ANVVPVSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYGhGNV
  .. | .|..| ||||||. .||. |.  |  |. |..|.|||||||  |||   ||||. ..|.... ||||||| |.. ..|||..|   | | ...
palleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhevrkvnrlygfkeelarkrg.srl

HKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRA--QEVPNKGPLCDIMWSDPDDDVEDWV--ISQRGAGFVFGAKVTEEFLMNNDLSLL
 | . .||. |.. | ... .||.|||.|..| . .||  | .   .   ..|   |..|.||. |  | .    ||.   ||| |. ...| .  |||.
wkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkqraisvvfgkkglddllkklalsli

CRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEID
 |.|.. .|||...|..|| ||.||| |. .  |  |. .. 
vrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvs
subfamily_PPP5C_pd Subfamily PPP5C 68-315 6e-79 258.4 In-house 61-310 (322) alignment 
Range on Protein: 68-315
Range on HMM: 61-310/322.0
VPVSSPVTICGDIHGQFYDLLELFKTGGTVP-NTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYGHgNVHK
.. .. .|.||||||||||||..|.  |..  .  |.| ||.|||| .|.|.. .|... | |||.. | |||||| .. ..||| .|...|| . .| .
ieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrGnhesdnmnklyGfegevkakyte.kvad

WFCKVFDVLPIGALIDESVLCVHGGL-SPDIRTIDSLMLLDRAQEVPNKGPLCDIMWSDPDDDvEDWVISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQ
 | .||. ||.. .|.|.|| ||||| | |  |.| |  .|| .. |..| |....||||..  .    |.|| |. ||  ||..|| .|.|.|. |||.
lftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqea.nGrspskrGvgvqfGpdvtkkflkennleliirshe

LVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEIDGNNRST--KYFNAVP
. .||.. . . || ||.|||||| . || .|. .. |..     | |.||.
vkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfeave
subfamily_PPP7C_pd Subfamily PPP7C 69-208 2.3e-38 124.9 In-house 61-202 (383) alignment 
Range on Protein: 69-208
Range on HMM: 61-202/383.0
PVSSPVTICGDIHGQFYDLLE-LFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKY--GHGNVH
 .|  ||.|||.||.. |||  |.| |   ..  ||| ||.||||. |.| . .|..||| ||... | |||||   .   |||  | ..||   . .. 
aiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhilnlryGfikeveskykvhgkkil

KWFCKVFDVLPIGALIDESVLCVHGGLSpDIRTIDSLMLLDRA
. . .||  ||...||||..| ||||.| |.  .. |  ..| 
rlledvfawlplatlidekilivhGGis.dktdlelldkiers
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 70-300 6.3e-55 179.7 In-house 5-241 (263) alignment 
Range on Protein: 70-300
Range on HMM: 5-241/263.0
VSSPVTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYGHGN----VH
. .|. |||| |||. ||| .|.. |.  .|.|.|.||||||| .||| . ||| | |  | .. ||||||| . | . |||. | .... . .    |.
lqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevyesvy

KWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPL-CDIMWSDPDDDVEDWVISQ-RGAGFVFGAKVTEEFLMNNDLSLLCRS
. | .||  .|. |.. . .||.|||.|| ....| .  .    |  .  || ||..|.||. | . .   . |    ||| |  ...    |. |. |.
nhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidlivra

HQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFE
||.|. |. .. . .| ||.||  |     | |||  
hqvveygyaffadrrlitvfsasryqielcnyaavvv
Metallophos Calcineurin-like phosphoesterase 73-267 1.2e-40 133.0 Pfam-A 2-199 (200) alignment 
Range on Protein: 73-267
Range on HMM: 2-199/200.0
PVTICGDIHGQFYDL----LELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLL--FCLLLKYPNQITLLRGNHESRRISNVYGFYDECQ----------
.....||.||...||    |.|.| ..  ... ..|.||.|||| .|.||  ||  ..| |..|... ||||||||. .  .|||..|.           
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange

-----------------------NKYGHGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRTIDSLmlldraqevpnkgplcdimwsdpdddvedwv
                       .... ...   ....|. ||. ||.|  .|..||.||..  . |                                 
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................

isqrgAGFVFGAKVTEEFLMNNDLSLLCRSHQLV
     ... || ...|..| .... |..|.|. .
.....gselfgpdalekllekygvdlvlrGHtHk
PPP_2 74-266 1.4e-78 256.2 In-house 1-197 (198) alignment 
Range on Protein: 74-266
Range on HMM: 1-197/198.0
VTICGDIHGQFYDLLELFKTGGTVPNTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYGHGNVHKWFCKVFD
||.|||.|||..|||.|||.|...|..||.|.|||||||..|||...||..| |.||....||||||||.....||||..|...|.|. .|.| ...||.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe

VLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVPNKGPLCDIM----WSDPDDDVEDWVISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQL
.||..|||||.||.||||||..|...|.    .| .|.|..|.|.| .    .|||... | .  |.||||..||..||||.| .|.|.|..|.|..
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
PPP_4 74-266 1.1e-73 240.6 In-house 1-196 (197) alignment 
Range on Protein: 74-266
Range on HMM: 1-196/197.0
VTICGDIHGQFYDL-LELFKTGGTVP-NTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKyGHGNVHKWFCKV
||..||||||..|| |.|.|.||  . ...|||.|||||||..|||...||..| |.||....||||||||. ....|||..|...|  . .. |....|
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek.hgkeilkklqdv

FDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVP-NKGPLCDI-MWSDPDDDVEDWVISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQL
||.||. |||||.||.||||||......|..  ..|..|.| ... ..|. .|||| .. | .  |.||||..||..|||.|| .|.|.|..|||.|
fdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel
PPP_5_Dcr2 74-266 1.9e-73 239.7 In-house 1-198 (199) alignment 
Range on Protein: 74-266
Range on HMM: 1-198/199.0
VTICGDIHGQFYDL-LELFKTGGTVP-NTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYGHGNVHKWFCKV
||.|||.|||..|| |.|||.||  . ...|||.|||||||..|||...||..| |.||....|||||||.. ....|||..|...||.. .. |....|
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv

FDVLPIGALIDESVLCVHGGLSPDIRTIDSLMLLDRAQEVP-NKGPLCDI-MWSDPDDDVED-WVISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQL
||.||. |||||.||.|||||||.|..|..|  ..|..|.| .||  .|. .|||| |..|. .. |.||||..|| .|||.|| .|.|.|..|||.|
fdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshel
subfamily_YNL217W_pd Subfamily YNL217W 75-142 6.9e-08 25.3 In-house 13-76 (235) alignment 
Range on Protein: 75-142
Range on HMM: 13-76/235.0
TICGDIHGQFYDLLELFK--TGGTVPNTKYVFMGDYVDRGHYSLETVTLLfclllkYPNQITLLRGNHES
 . ||.|| . .|.||..  .||  .|   |..|| ...|  |.|.| ..        .|   ..|||| 
lvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnhee
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 99-305 1.3e-70 231.0 In-house 100-305 (317) alignment 
Range on Protein: 99-305
Range on HMM: 100-305/317.0
NTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYGHgNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRT
. ||.|.||||||| .|.| |.|||.| |.||....||||||||| .   |||| |....| . .... | ..| |||. |.... .||.|||.| ..  
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysa.alyeafqlafnvlplcavvnkkilcmhGGiseelld

IDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAV
.. |  |.|  ..|. | |.|. |.||| .|. .  |.||||.|||||  .||| . || |. |.||.| .|.... . || |..|||.|| .  |.|||
lkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaav

FEIDGNN
...| . 
lsvdkkl
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 99-305 3.9e-59 193.4 In-house 119-324 (339) alignment 
Range on Protein: 99-305
Range on HMM: 119-324/339.0
NTKYVFMGDYVDRGHYSLETVTLLFCLLLKYPNQITLLRGNHESRRISNVYGFYDECQNKYGhGNVHKWFCKVFDVLPIGALIDESVLCVHGGLSPDIRT
  .|.|.||||||| .|.| | || .| | ||..| ||||||||| .   |||| | . .|   .... | ..|.|.|. |.|.....|.|||.|  . .
ykrylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyryd.aqlyecfqnmfnvfpfcavinntimcmhggisehlts

IDSLMLLDRAQEVPNKGPLCDIMWSDPDDDVEDWVISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAV
.. . .. |  |.|. | | |. |.|||   . .  | ||| ||||      || . || .. | ||.|..|....   .| |..|||||| .  |.|||
fnqfsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaav

FEIDGNN
| || . 
fsidkkl
subfamily_PPP7C_pd Subfamily PPP7C 217-301 4.2e-19 61.5 In-house 237-321 (383) alignment 
Range on Protein: 217-301
Range on HMM: 237-321/383.0
LCDIMWSDPDDDVEDWVISQRGAGFVFGAKVTEEFLMNNDLSLLCRSHQLVDEGFKYMFNEKLATVWSAPNYCYRCGNAAAVFEI
. ||.||||  .   .  . ||.|  ||. ||...| . .|.|| |||.   ||.... ..|. |..|| ||     |  |   .
vldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvkl