Gene tax-6 in Caenorhabditis elegans

Synonym: CELE_C02F4.2, tax-6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP3C
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP193_AA protein Get Run
CeleP193_AA_107-310 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0045823 Metallo-dependent phosphatases 39-509 7e-152 499.2 In-house 2-471 (473) alignment 
Range on Protein: 39-509
Range on HMM: 2-471/473.0
ERFVKTVQFPVSERLTVDQVYDRRtGKPRHEVLRDHFIKEGRIEEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKY
.|..|.|..||. .||.. ....  |.. ...|..|..|||...|| ......|. .....|...||......|.||||||..||..|.|  | |  ...
drvlklvlipvlrlltlpllfill.glldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrl

LFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIR
.||||.||||..|.|....|.||||.||.  ||||||||.|.|. .. |..|.  ||.|..|. ..| ...|||||. ....|.|||||||....|..||
vflGDlvDrGpdslevlelllalkikypgnvfllrGNHElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqir

RIDRFKEPPAFGPMCDLLWSDPLEDFGNERNSEQFSHNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLD
.|.|. |.| .|...||||||| ||.|...  . | .||.||..|.... | ..||..|.|  |.|.|.... ||..... ...|....||.||||||..
eierpleipddgllldllwsdPweddgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcg

VYNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVHILNICSDDELMaECDDTFEGGVGSARKEVIRHKIRAIGKMARAFSV
...|.||.|..........||..||||..||.|.|||..||||..||.||.|...|||.|||||. | .| ..  . .|..|..|.||.|.||..| |||
rggnlaAvlvidedlisfiqfdpsphplilplfldvfllslpfllekltellllllnivsddell.ededilglllleallellrnkilalgkllrvfsv

LRHESESVLQLKGLNAGGKLPQGALSEGRTGLNAAYRIEQSVA-AESGCDSGHLIQSFEEARRLDKINERMP
|| ||||||.||||.  | ||.|.|..|.. |  ... . ..   .. ... .|..|.||.. |..||||..
lreesesvlllkgltpsgllplgllllgkelllesleealkldlineklppsllllsleeekslelinerle
subfamily_PPP3C_pd Subfamily PPP3C 40-510 4.2e-258 849.5 In-house 1-452 (452) alignment 
Range on Protein: 40-510
Range on HMM: 1-452/452.0
RFVKTVQFPVSERLTVDQVYDRrTGKPRHEVLRDHFIKEGRIEEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYL
|.||.|..| |..|| ..|.|. ||||..|||..||.||||.|||||...|.|...|...|||.||.|||.||.||||||||||.|||||||.||.||||
rvvkkvplpkskklteeevfde.tgkpklevlkehflkegrleeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkyl

FLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRR
|||||||||||||||||||.||||.||.|||||||||||||||||||||.||||||||.||| ||||||.||||||.|||||||||||||||..|.||..
flGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecrhlteyftfkeeckikyseevydacmesfdslPlaallnqqflcvhGGlspeikslddikk

IDRFKEPPAFGPMCDLLWSDPLEDFGNERNSEQFSHNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDV
.||||||||.||.|||||||||||.|.|...|.|..||||||||||||.|.|.|||.|.|||||||||||||||||||||.|||||||||.|||||||||
ldrfkeppasGplcdllWsdPledygeekteekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldv

YNNKAAILKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVHILNICSDDELMAECDDT-FEGGVGSARKEVIRHKIRAIGKMARAFSV
||||||.||||||||||||||.||||||||||||||||||||||||||||||.||||||||||..| ...  |    ..||||||.|||||||.|| |||
ynnkaavlkyennvmnirqfnssphpywlpnfmdvftwslpfvgekvtemlvnilnicsddelekeeeeeskeesesekrkevirnkiraigklarvfsv

LRHESESVLQLKGLNaGGKLPQGALSEGRTGLnaayrieqsvaaesgcdsGHLIQSFEEARRLDKINERMPP
||.||||||.||||.  |.||.||||||..||                   . ..|||||..||.|||..||
lreesesvlllkglt.tgalprgalsegkegl..................eeklssfeeakkldlineklpp
0049330 Metallo-dependent phosphatases 65-368 7.5e-97 317.1 In-house 14-305 (309) alignment 
Range on Protein: 65-368
Range on HMM: 14-305/309.0
KPRHEVLRDHFIKEGRIEEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKIC
..  ..|.....|.....|| ........ .....|...||......|.||||||..||..|.|  | |  ....||||.||||..|.|..|.|.|||..
lslldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalkll

YPTTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPLEDF
||   ||||||||.|.|. .. |..|.. ||...... ... ...|||||. ....|||||||||....|..||...|. |.|..|..|||||||||...
ypdnvfllrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpir

GNernseqfSHNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENN-VMNIRQFNCSP
 .        ....||..... . | ..||..|.|  |||.|.|.. ||... . .      |||.||||||.....|..|.|..... |.....|...|
eg.......fapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgk......litvfsapnycgrlgnlgavleidedlvisfllfepvp

HPYWL
....|
lllll
0053225 Metallo-dependent phosphatases 66-360 1.7e-90 296.4 In-house 7-289 (293) alignment 
Range on Protein: 66-360
Range on HMM: 7-289/293.0
PRHEVLRDHFIKEGRIEEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICY
. ...|......  .. || ......|. .....|...||......|.|||||...||..|.|  | | .....||||.||||..|.|....|.|||..|
llldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalklly

PTTLFLLRGNHECRHLTEYFTFKQECKIKY-SERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPLEDF
|.  .|||||||...|. .. |..|.. || .....| ... ...|||||| ....|.|||||||....|..||.|.|. ..| .|...||||||| . .
pdnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpdlws

GNERNSeqfshnsvRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKsqatgfPSLITIFSAPNYLDVYNNKAAILKYENN-VMNIRQFN
|   .         ||..... . |...||..|.|  |||.|.... ||... .      ..|.|.|||||||....|..|.|..... |... .|.
gwlpsy........rglgvvfghtavlrflkkngldliirghqvvpdgylpwfd......gklvtvfsapnylgrlgnlgavlaldeglvwgfklfa
subfamily_PPP5C_pd Subfamily PPP5C 72-367 3.3e-83 272.4 In-house 25-314 (322) alignment 
Range on Protein: 72-367
Range on HMM: 25-314/322.0
RDHFIKEGRIEEEAAIRVIQECSSLFRNEKTMLEIEAP----VTVCGDIHGQFYDLMKLFEVGGSPATT-KYLFLGDYVDRGYFSIECVLYLWALKICYP
 ..| |. ....  |.....| ..|.... ...||. .    .|||||||||||||. .||. |.|...  ||| ||.|||| ||.|..| |...|. ||
lelfkkqkklhkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyP

TTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLS-PEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPLEDFG
  .|| |||||  .. . . |..|.| ||.|.|.|.  |.|. |||| ..|...| |||||   .  ||.|.|.|||...||  | ...|||||| |  |
nhfflsrGnhesdnmnklyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqeanG

NernseqfsHNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKY--ENNVMNIRQFNCSP
          .| || .  .       ||..|||  |||.|| .. ||.. .. .      |||.|||||| |  .||.|...   ... .....|.  .
r........spskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGk......litvfsapnycdqmgnkgafitlrgddlklkfktfeave

HPYW
||  
hpdv
subfamily_PPP7C_pd Subfamily PPP7C 77-244 1.7e-33 108.9 In-house 29-203 (383) alignment 
Range on Protein: 77-244
Range on HMM: 29-203/383.0
KEGRIEEEAAIRVIQECSSLFRNEKTMLEIE----APVTVCGDIHGQFYDLMKLFEVGGSPATT-KYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFL
.. ..  .  . ...|.   ... . . ...      ||||||.||.. ||. ..   | |..   |.| ||.||||  |.| .| | || . ||. ..|
ekkllhakyvllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevyl

LRGNHECRHLTEYFTFKQECKIKY---SERVYDVCMESFDALPLAALMNQQFLCVHGGLSpEIHTLEDIRRIDRFK
 |||||   |   . | .| . ||   ....  .  . |  ||||.|.... | ||||.| ..  || . .|.| |
nrGnhedhilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGis.dktdlelldkiersk
subfamily_PPP2C_pd Subfamily PPP2C 78-363 1.3e-80 263.7 In-house 13-287 (290) alignment 
Range on Protein: 78-363
Range on HMM: 13-287/290.0
EGRI-EEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNH
|..  ||.   .....   ....|. . |...|||||||.||||.||..|| .||.   |.||||||||||||.|.|.| .| |||. |.  . .|||||
eckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvrykeritilrgnh

ECRHLTEYFTFKQECKIKYSE-RVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPledfgNERNSeqFsH
| | .|. . | .||  ||..  |. .  . || |||.||...| .|.||||||.|.||..|| .||..| |  ||.||||||||     ..|.   .  
esrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdp.....ddrgg..w.g

NSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNV-MNIRQFNCSP
 | ||. | .    . .| ..|.|  |.|||.    ||..  . .      ..||||||||     |.||||. .... ... ||. .|
isprgagytfgkdisekfnktngltliarahqlvmegynwshdrn......vvtifsapnycyrcgnqaailelddklkysflqfdpap
subfamily_PPP1C_pd Subfamily PPP1C 80-354 8.6e-88 287.2 In-house 9-270 (282) alignment 
Range on Protein: 80-354
Range on HMM: 9-270/282.0
RIEEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECR
...|.   .....  ... .. ..||.||||...||||||..||..||| .|.|....||||||||||| .|.| .. | |.|| ||..|||||||||. 
klkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesa

HLTEYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPledfgnERNSEQFSHNSvR
...... |. ||| .|| ... . .. |. ||||||.... ||||||||||.. ||.||.| |  | |  | .||||||||      .......|.|. |
sinriyGfydeckrrysiklWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdp......dkevlgwsend.r

GCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNVM
| |. ..  .  .|||.|.|  |.|||.  ..||... | |      |.|.||||||.. ..|..|.|. .....
GvsftfgkdvvekflqkndldlivrahqvvedGyeffakrq......lvtvfsapnycgefdnagavlsvdeell
subfamily_PPP4C_pd Subfamily PPP4C 80-354 8.6e-84 274.2 In-house 15-276 (288) alignment 
Range on Protein: 80-354
Range on HMM: 15-276/288.0
RIEEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECR
 |.||   .. .. . .. .|  . ....|||||||||||||||..||.|||.   |.||||||.||||..|.|. | | |||. ||  . |.|||||.|
likeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesr

HLTEYFTFKQECKIKY-SERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPLEdfgnernSEQFsHNSV
..|. . | .||  || | .|. .|.| || |.|||..... .||||||||.|.||..|| ||| .| |  ||.|||||||| .        | .   | 
qitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdped.......aegw.avsp

RGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNVM
||  |..   .. .| ..|..  |.|||.    ||... . .      ..|..|||||     |.||||...... 
rgagylfgsdvveqfneandielicrahqlvmegyklhfnek......vltvwsapnycyrcgnvaaileldeeld
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 80-354 2.9e-78 255.9 In-house 23-285 (298) alignment 
Range on Protein: 80-354
Range on HMM: 23-285/298.0
RIEEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECR
 |.||   ..|... ..|.. |...|..||..||||||||. ||..||. .| | .. ||||||||||| ...| .. | | |. ||. .||||||||| 
vikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnffllrGnhece

HLTEYFTFKQECKIKY-SERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPledfgnERNSEQFSHNSv
.. . . |..||| .| | |.|    . |.||||.||. .. ||.|||||.....|...|.. | ....      ||||.||      |.. .....|| 
ainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadp......enavkgwaens.

RGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNVM
|| |. .   .  |.|.. ..  ..|||     || .. . .      |.||||||.|.. ..| ||..| .....
rGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekk......lvtifsaphycgqfdnsaavmkvdeklv
PPP_3 81-354 5.9e-97 316.9 In-house 2-263 (271) alignment 
Range on Protein: 81-354
Range on HMM: 2-263/271.0
IEEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRH
..|. . .......... .|....||.||||||||||||..||..||..||....|||||||||||||..|.|..|.|.|||| ||....|||||||.|.
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq

LTEYFTFKQECK-IKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPLedfgnerNSEQFSHNSVR
......||.|..  |....||....| |..||||||.....|.|||||||.|..|..|....|..| |  |...|||.|..        ..|.. .||.|
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdp.......ekeeglenskr

GCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKsqatgfPSLITIFSAPNYLDVYNNKAAILKYENNVM
|......  . ..||..|.|  ||||||....||.....       ...|.||||||.. ..|..|||| |.. .
GagllFgpdvteefleknkLkliiRaHelkeeGyeilhd......gkvvtvfSapnycerasnagailkleealt
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 81-352 3.2e-70 229.4 In-house 6-264 (280) alignment 
Range on Protein: 81-352
Range on HMM: 6-264/280.0
IEEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRH
|.|    |||..|  ..  ..||.|..|||.||||.|||. ||..||.  . |  ..||||||||||| . .| .| | | |. || ....||||||. .
ikeadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevis

LTEYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPledfgnERNSEQFSHNSvRG
. . . ||.|.| .||. .|.   | .| |||.||.. . ||.|||||... .|.|.... |  ...      ||||.||      | .   ...|| ||
inrkygfkdevkrryslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadp......enkvtgwaens.rg

CSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENN
.|. .      |. .. ..  |.| |.  . || .. . .      |.|.||||.||. ..|.||.|. ...
vsvifganvvkdltekldidliarghqvvqdgyeffadkk......lvtvfsapkylgefdnsaavlivder
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 81-354 3.7e-65 213.1 In-house 24-285 (299) alignment 
Range on Protein: 81-354
Range on HMM: 24-285/299.0
IEEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRH
..|.  ... . . | | .. ..||.|||. ||||||||. ||...|.. | |  ...||||||||||   .| .  | . || ||  .|.|||||||  
vkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhecpa

LTEYFTFKQECKIKY-SERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPledfgnERNSEQFShNSVR
.   . | .||. .| | |.. .  ..|.|.||. |.. . ||.||||||...||. .| . | ..||.     ||||.||      ..   ..  . ||
inrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadp......dqsvkdwl.anvr

GCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNVM
| || .      | ... ..  . |||.  . || .. . .      |.|||||| |   ..| |||.| ..|..
gvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskk......lvtifsaphycgqfdnsaaimkvdenlv
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 81-351 1.7e-62 204.3 In-house 23-283 (297) alignment 
Range on Protein: 81-351
Range on HMM: 23-283/297.0
IEEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRH
| ||  ..... . ..|...|.|.|..||. ||||||||| ||..||  || | |..||||||||||| |||| .. | | |. .|. ||||||||||  
iteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhecef

LTEYFTFKQECKIKY-SERVYDVCMESFDALPLAALMNQQFLCVHGGLSP---EIHTLEDIRRIDRFKEPpAFGPMCDLLWSDPLEDFgnernSEQFSHN
. . . | .||. .| | |.|    . |. |||. |. .. ||.||||||   .  ||. .|.|.| .|    . ..||||.||.  .     |  .  .
vnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisgl.....sgfmenq

SVRGCSyfYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYEN
   ||   .   |  .   . .|  . |||.  . || ..   .      |.|||||| |   ..| ||..  ..
rgagcg..fgrdavlklcsefkldlvcrahqvvqdgyeffagrk......lvtifsaphycgqfdncaafmscde
PPP_1 82-348 2.8e-106 347.6 In-house 2-263 (264) alignment 
Range on Protein: 82-348
Range on HMM: 2-263/264.0
EEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHL
||| ....... ..|...|...||.....||||||||||.||.|||.|||....|.|||||||||||..|.|..|.|.|||. || .|||||||||.|..
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqv

TEYFTFKQECK-IKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPLEDFGNERNSEQFSHNSVRG
|....||.|..  |||...|......|| ||||||.....|.||||||||...|..||...|..| |. |..||||..|  ... .....|.. .||.||
tkvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRG

CSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILK
..|.... . ..|||.||| .||||||....||....|..      ..|||||.|| .. .|..|..|
agylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrk......vvtifsasnyyeegsnrgayvk
PP2Ac_SM00156 82-354 2.9e-106 347.5 In-house 2-261 (271) alignment 
Range on Protein: 82-354
Range on HMM: 2-261/271.0
EEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHL
..| ......|. .....||...|..|||||.||||||..||..|.| .| |...||.|||||||||..|||..|.|.||||.||....|||||||....
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssv

TEYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPledfgnERNSEQFSHNSvRGC
.....|..|.|.||....|....| |..||||||.....||.|||||||...|.|||...|.||.|  |...|||||||      |.. ..|.... ||.
nkiygfeeevkrkygkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdp......eqkekgfqpsk.rgl

SYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSqatgfpSLITIFSAPNYLDVYNNKAAILKYENNVM
|.... .| ..||..|||  ||||||..| ||... ..      .|.||||||||.| ..||||.||.|.|..
svvFgedavkeflkknnlkliiRahevvdeGyeffadk......klvtifsapnycdefsnkaavlkveknlk
subfamily_PPP6C_pd Subfamily PPP6C 82-359 7.1e-75 244.8 In-house 16-281 (290) alignment 
Range on Protein: 82-359
Range on HMM: 16-281/290.0
EEEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHL
 |. . .. .  . |. .| ..  ...|||||||||||||||..||  ||.   |.|.||||.|||||.|.| . .| .||. ||  . |||||||.|..
pendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqi

TEYFTFKQECKIKYSE-RVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPlEDFgnernsEQFsHNSVRG
|. . | .||. || .  ..  |.. || |..||....| |||||||||...||..|| |.| .| |  |..|||.|||| ||       |.. . | ||
tqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdp.edv......etw.avsprg

CSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNV-MNIRQF
  |..    . .|.. |||  |.|||.  . |.. . . .      |.|..|||||     | |.||. |..   . . |
agylfgskvtkefvhinnlklicrahqlveeglkymfdek......lvtvwsapnycyrcgnvasilaledaeereaklf
subfamily_PPG1_pd Subfamily PPG1 82-352 2.6e-73 239.9 In-house 14-285 (300) alignment 
Range on Protein: 82-352
Range on HMM: 14-285/300.0
EEEAAIRVI-QECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRH
  |.... . .    |. .|  . ||..|||| ||.||||||....|..||    |.|||||||||||..|.| .  | .||. ||. . ||||||| | 
lpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhesrq

LTEYFTFKQECKIKY--SERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPLED----FGNERNSEQFS
.|. . |  ||  ||    ||..   | || | |||.....  ||||||||.. ....|. .|||.| |  | ..||||||| |.    . .  .. |. 
itqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdregqhf

HNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENN
 .| ||. | |       ||. |..  |||||.    ||...  ..      | |..|||||     |||.||. ...
vvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnk......lstvwsapnycyrcgnkasilelyek
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 83-353 4.2e-68 222.6 In-house 10-267 (281) alignment 
Range on Protein: 83-353
Range on HMM: 10-267/281.0
EEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLT
.|  . ||.|  ..| .||.. ||..|..| ||.|.|| || .|||. | .. ....|||||||||  |.|... |..|||.|.  ..|||||||  .. 
keeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasvn

EYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPledfgnERNSEQFsHNSVRGCS
  . | .||. || | ..    . |. ||..||.... ||.|||||||. .|...| . .  ...  | . ||||.||      . ..|.. ..|.|| |
kiygfyvecvtkyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadp......dnkveew.kassrGss

YFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNV
. .  .   |  .. ..  |||||    .||..    .      |||.||.||| . |.| ||.|| ....
ftfGknvvddvckrleveliirahqvvqdGyevlsgrk......litvfsvpnycafyknaaavlkvdetl
subfamily_PPZ_pd Subfamily PPZ 83-351 8.2e-64 209.0 In-house 27-282 (300) alignment 
Range on Protein: 83-351
Range on HMM: 27-282/300.0
EEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLT
..  ... ...  || .. ..||.  .| . ||.|||. ||..||   | | ...|||||||||||  |.| .| |.. || ||  .|||||||||  .|
nseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnhecanvt

EYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPLeDFGNERNseqfshNSVRGCS
  . | .||| .   ...   ...|..|||||..  . .|||||||| . ....||.. |  . | || . |||||||  |  || .      .  || |
rvygfydeckrrcnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdpt.dssnewe......dnergvs

YFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSqatgfpSLITIFSAPNYLDVYNNKAAILKYEN
| |   |   ||..  .  . |||   . || ..         ||.|.||||||   ..|  |..   .
ycynkvainkflnkfgfdlvcrahmvvedgyeffndr......slvtvfsapnycgefdnwgavmsvse
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 83-353 6.3e-63 205.7 In-house 8-290 (302) alignment 
Range on Protein: 83-353
Range on HMM: 8-290/302.0
EEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGG-----------SPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFL
..  . .|..  .|...|||. || .|||. ||||||| ||....               | .. |..|||||||||. ||||.  ..|||..|||   |
ksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyil

LRGNHECRHLTEYFTFKQECKIKYSERV----YDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAF-GPMCDLLWSDPLEDFG-
||||||.. .   ..|..| .......     ..   | |  .|||||. .. ||||||.|| ...||||..|.|  .  .      |||..|||.  . 
lrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqll

-NERNSEQFSHNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNV
   ..  .. .| ||| |. .  ||  |. .. ||  |.|||    .|.... . .      |.||||||.|..  .|| |.|| . | 
aavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkk......lltifsaprymnesdnkGavlkvdtng
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 83-353 1.1e-62 204.9 In-house 9-291 (302) alignment 
Range on Protein: 83-353
Range on HMM: 9-291/302.0
EEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGG-----------SPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFL
..  . .|..  .|...|||. || .|||. ||||||| ||....               | .. |..|||||||||. ||||.  ..|||..|||   |
ksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyil

LRGNHECRHLTEYFTFKQECKIKYSERV----YDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAF-GPMCDLLWSDPLEDFG-
||||||.. .   ..|..| .......     ..   | |  .|||||. .. ||||||.|| ...||||..|.|  .  .      |||..|||.  . 
lrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqll

-NERNSEQFSHNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNV
   ..  .. .| ||| |. .  ||  |. .. ||  |.|||    .|.... . .      |.||||||.|..  .|| |.|| . | 
aavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkk......lltifsaprymnesdnkGavlkvdtng
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 83-349 6.3e-57 185.8 In-house 18-275 (290) alignment 
Range on Protein: 83-349
Range on HMM: 18-275/290.0
EEAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLT
..  . ....  ....   ..||.|||... ||||||. .|.. |.  | |   |.||||||||||  |.|  |.|. .|| |. .. |||||||.|.. 
dkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhevrkvn

EYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPP--AFGPMCDLLWSDPLEDfgnerNSEQFSHNSVRG
  . ||.|   | . |.. .  . |. |.| | .... ||.|||.|..|.. | .. . . . |     | . ||||.|| .|      .. .. |  |.
rlygfkeelarkrgsrlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrd.....kddtialnkqra

CSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKY
 |  .   .  |.|..  |  |.|||| .. |. .  . .      |.|.|||| |     |  ||.. 
isvvfgkkglddllkklalslivrahevkeegfnflfdkk......lvtvfsapyysgndtnlgaiatv
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 84-351 9.2e-68 221.2 In-house 13-270 (287) alignment 
Range on Protein: 84-351
Range on HMM: 13-270/287.0
EAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTE
.  . |...  ....  ...||.|||.|..||||||. ||...|.  | .. ..|||||||||||  |.| .|.|..||| ||  . |||||||.... .
kdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevkkink

YFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAF--GPMCDLLWSDPledfgnERNSEQFSHNSVRGC
 . ||.| | |..||.| .  . |. ||| | .... ||.|||.||....|.... . . . | |   | . ||||.||      |.... |  | .|. 
lyGfkeelkrkrqerlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadp......ekdaktfelnkirai

SYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYEN
|  .      |.|.. ..  |.|||| .. || .. . .      |.|.|||| |     | .|... ..
svvfGkkevddllkkldidlivrahevseeGyaflfdkr......lvtvfsapyysgedtnlgavvvvsk
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 84-354 2.2e-67 220.5 In-house 11-274 (284) alignment 
Range on Protein: 84-354
Range on HMM: 11-274/284.0
EAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSP------ATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHE
.  |..   .  || .||  |||||||...||||||| ||. |... | |        .|||||||||||| |||| .. |.|.|. .|  .||||||||
kelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrgnhe

CRHLTEYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPLEDFgnernseQFSHNS
 | .   . | .||| .|||..|..   .| |.||.|..... .|.|||.| ..  |... ...|  . |  | ..|| |.|| ..        .  ..|
srpvnmqygfyleckkrysealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaev.......egykes

VRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNVM
 ||.   .  .|  .||.. .|  ..|||.    || ..   .      |.|||||| |   ..| ||.|. .....
prgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrk......lvtifsapsycgqldniaavlnvdeelv
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 84-352 8.2e-53 172.6 In-house 23-281 (307) alignment 
Range on Protein: 84-352
Range on HMM: 23-281/307.0
EAAIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTE
|    || |. ..|  ||....|. |. | ||.|||| ||...| . | |  | |.| ||||||| .|.||.| |.. |||||  . |||||||  .. .
eefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnk

YFTFKQECKI---KYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPLEDFGNernseqfSHNSVRG
 ..| .||     |  | .. .    |. ||..||.  . ||.|||||| .  |...|   .    |  | . |.||.||     .        . | ||
kygfyeecvtsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfe.......wkassrg

CSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSqatgfpSLITIFSAPNYLDVYNNKAAILKYENN
  . .      |  .   .  |||||.    || .           |||||||| | ..|.|  ..|| .. 
sgftfgtnviddvckrlgveliirahqmcfdgywvlsgr......klitifsapmycnfyknagcvlkvdet
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 86-358 4.5e-56 183.3 In-house 11-271 (280) alignment 
Range on Protein: 86-358
Range on HMM: 11-271/280.0
AIRVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTEYF
 | .|.   ..| .|  . | |||. | |||| |. |. .||.. |     | .|||||||||   || .. |..||| |   ..|||||||   . . .
iiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnkiy

TFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLWSDPLEdfgnerNSEQFSHnSVRGCSYFY
 |  ||. ||   ..      |. .|...|.... ||.|||||||.  |. || | |  ||   | . ||||||| .      . | . | |.|| ||..
gfyvecqykygvglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptn......kgegwfh.sirgisymf

SYAACCDFLQHNNLLSIIRAHEAQDAGYRMYrksqaTGfPSLITIFSAPNYLDVYNNKAAILKYENNVM-NIRQ
  .   .  .  ..  |||||.  . || |      .|   |||.|| |||   . | ||..  . |.  ...|
gkgvveqacksleidliirahqvvqdgyemm.....ag.rrlitvfsvpnycaqftnaaavvclnanlqvsfqq
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 88-353 2.4e-57 187.5 In-house 10-264 (284) alignment 
Range on Protein: 88-353
Range on HMM: 10-264/284.0
RVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTEYFTF
 .. .. |.| ..  ..|...|. .|||||||| ||..||.  | |  ..|||||||||||   .| .| |.| |. .|  .|.|||||||  . . . |
tllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiygf

KQECKIKYSE-RVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDR-FKEPPAFGPMCDLLWSDPLeDFGNERNseqfsHNSvRGCSYFY
 .||. .| .  ||      |  .||.||. |. ||.|||.|  .. . ..| | | | .|       |.|||||  .| .  |      || || || .
yeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdpt.nfqkgwn.....pns.rgvsyvf

SYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNV
   |   .|.. ..  ..|||.  . || .. . .      |.|||||| |   ..| ||..  ..|.
gsdalrklldrlqidlvvrahqvvqdgyeffanrr......lvtifsapfycgqfdnaaavmyvnknl
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 88-135 5.7e-12 38.4 In-house 16-63 (317) alignment 
Range on Protein: 88-135
Range on HMM: 16-63/317.0
RVIQECSSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPAT
 .      || .|. .||.|||||..||||||| ||. |... | | .
elcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwpls
subfamily_PPPLV_pd Subfamily PPPLV 94-354 7.7e-58 189.1 In-house 10-281 (290) alignment 
Range on Protein: 94-354
Range on HMM: 10-281/290.0
SSLFRNEKTMLEIEAPVTVCGDIHGQFYDLM----KLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTEYFTFKQ
   . .|. .||...|. | ||.||.. ||.    .|. .|   . ...|||||||||| ||.| . || |||. ||. ..||||||| . ..| ...| 
vdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvqesieykg

ECKIKYSE---RVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRI----DRFKEPPAFGPM-CDLLWSDPLEDF-----GNERNSEQFSHN
|.. |. .    |..  .. |||||||| .... .|||.|.   |.|   |  |    .|.|..    |.  |.||||| ||      |.   .| | .|
egsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvlneGfvdn

SVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYENNVM
. || .. .| .|   ||..|||  ..||||....|.|. .|..      |.|.||. .|    |. | ||  .... 
drrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgr......lltvfsssrycGssneaalilvdkkklr
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 94-135 2.3e-07 23.2 In-house 24-65 (339) alignment 
Range on Protein: 94-135
Range on HMM: 24-65/339.0
SSLFRNEKTMLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPAT
  |   |  .|..|||. | ||||||| ||. .... | | .
reliwsepiflkleapicvmgdihgqfddllamldmngwpls
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 103-348 2.1e-50 164.8 In-house 2-241 (263) alignment 
Range on Protein: 103-348
Range on HMM: 2-241/263.0
MLEIEAPVTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTEYFTFKQECKIKYS-ERV--
.||..||. .||| |||. ||...|.  |. . |.||||||||||| .|.| .. |..||.. |  ..||||||| . . . . |. | | ..  | |  
llelqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevye

--YDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPM-CDLLWSDPledfgnERNSEQFSHNSVRGCSYFYSYAACCDFLQH
  |.   . |  .||.|..... ||.|||.|| ...|.||| |    |     |. |||||.||      |.... |  | .|  |  .      |. ..
svynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadp......ekdakgfepnkiraisnvfgkkevddlckr

NNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILK
 ..  |.|||.  . || ..   .      |||.|||  |     | ||.. 
ldidlivrahqvveygyaffadrr......litvfsasryqielcnyaavvv
Metallophos Calcineurin-like phosphoesterase 109-309 2.6e-42 138.4 Pfam-A 2-199 (200) alignment 
Range on Protein: 109-309
Range on HMM: 2-199/200.0
PVTVCGDIHGQFYDL----MKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYL--WALKICYPTTLFLLRGNHECRHLTEYFTFKQECK----------
...|.||.||...||    ..|.......  . .|||||.||||  |.|.  .|  ..||. .|. .||||||||........ |. |.           
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange

------------------------IKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLEDIrridrfkeppafgpmcdllwsdpledfgner
                         ..  .... . | |.||||.|| ....|..||.||..  . .||                               
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................

nseqfshnsvrgCSYFYSYAACCDFLQHNNLLSIIRAHEAQ
            .|. ... | ...|. ...  ..|.|. .
............gselfgpdalekllekygvdlvlrGHtHk
PPP_4 110-309 9.6e-74 240.7 In-house 1-197 (197) alignment 
Range on Protein: 110-309
Range on HMM: 1-197/197.0
VTVCGDIHGQFYDL-MKLFEVGGSPA-TTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDVCMESF
|||.||||||..|| .||...|| |. ...|.|||||||||..|.|..|.|.|||. ||....|||||||...|.....||.|.. |....... ....|
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlekhgkeilkklqdvf

DALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPP-AFGPMCDL-LWSDPLedfgneRNSEQfSHNSVRGCSYFYSYAACCDFLQHNNLLSIIRA
| ||||||.....|.||||||.|...|..|.||.|..| |   . ..|| |||||       .. |. ..|||||....... . ..||..||| .|||.
dllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpr......eaqeg.lansvrGagllFgpdvtekfleknnlkliirs

HEAQ
||..
helk
PPP_2 110-308 3e-73 238.7 In-house 1-197 (198) alignment 
Range on Protein: 110-308
Range on HMM: 1-197/198.0
VTVCGDIHGQFYDLMKLFEVGGSPATTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTEYFTFKQECK-IKYSERVYDVCMESFD
||||||.|||..||..||..|......||||||||||||..|.|..|.|.|||. ||....|||||||.........||.|..  |....||. ..| |.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe

ALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPPAFGPMCDLLwsdPLEDFGNERNSEQFSHNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEA
.||||||.....|.||||||.||..|..|....|..| |. |...|||   . |.. .....|.. .||.||......  . ...|..|.|  ||||||.
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldll...eeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
PPP_5_Dcr2 110-308 1.9e-69 226.6 In-house 1-198 (199) alignment 
Range on Protein: 110-308
Range on HMM: 1-198/199.0
VTVCGDIHGQFYDL-MKLFEVGGSPA-TTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTEYFTFKQECKIK-YSERVYDVCMES
||||||.|||..|| ..||. || |. ...|.|||||||||..|.|..|.|.|||. || ...|||||||...|.|...|..|.. | .....|... ..
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv

FDALPLAALMNQQFLCVHGGLSPEIHTLEDIRRIDRFKEPP-AFGPMCDL-LWSDPLedfgneRNSEQFSHNSVRGCSYFYSYAACCDFLQHNNLLSIIR
|| ||||||.....|.|||||||||...|....|.|..| |   | ..|| |||||       .. |.   ||.||....... . ..||..|||  |||
fdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdpr......daqegcklnseRGagllfgpdvtekfleknnlkliir

AHEA
.||.
shel
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 135-353 6.2e-56 182.9 In-house 100-305 (317) alignment 
Range on Protein: 135-353
Range on HMM: 100-305/317.0
TTKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTL
  |||||||||||| |||| |. | |||. ||  .|||||||| | .   . | .|.| .||...|..    | .|||.|..|.. ||.|||.| |.  |
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldl

EDIRRIDRFKEPPAFGPMCDLLWSDPledfgneRNSEQFSHNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAP
. . ...|  . |  | ..|| |.||        ....  ..| || .  .  .|  .||.. .|  ..|||.    || ..   .      |.||||||
kqldklkrpldipdvGvladltwadp.......daevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrk......lvtifsap

NYLDVYNNKAAILKYENNV
.|    .| ||.|. ....
sycGqldniaavlsvdkkl
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 136-351 1.4e-43 142.3 In-house 120-322 (339) alignment 
Range on Protein: 136-351
Range on HMM: 120-322/339.0
TKYLFLGDYVDRGYFSIECVLYLWALKICYPTTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDVCMESFDALPLAALMNQQFLCVHGGLSPEIHTLE
 .||||||||||| ||.| |. | |||..||  ..||||||| | .   . | .| . .|  ..|..  . |. .|..|..|.  .|.|||.|  . ...
krylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyrydaqlyecfqnmfnvfpfcavinntimcmhggisehltsfn

DIRRIDRFKEPPAFGPMCDLLWSDPledfgneRNSEQFSHNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPN
..  . |  | |  | . || |.||         .|.  . | ||.|. .   |   ||.. .|  .|| |.  . || ..   .      |.|||||||
qfsvfkrpleipdvgvltdltwadp.......dptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrr......lvtifsapn

YLDVYNNKAAILKYEN
|    .| ||..  ..
ycgqndntaavfsidk
subfamily_PPP7C_pd Subfamily PPP7C 252-354 1.8e-12 39.7 In-house 237-326 (383) alignment 
Range on Protein: 252-354
Range on HMM: 237-326/383.0
MCDLLWSDPLEDFGNernseqfSHNSVRGCSYFYSYAACCDFLQHNNLLSIIRAHEAQDAGYRMYRKSQatgfpsLITIFSAPNYLDVYNNKAAILKYEN
. |.||||| .. |          |..||   ..      ..||. ||  .||.|| .  || .  ...      ..||||| || ..  |. | .|  .
vldilwsdpkakeGc.......kpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkk......vltifsasnyyeeGsnrGayvklgk

NVM
...
dlt