Gene W09D10.4 in Caenorhabditis elegans

Synonym: CELE_W09D10.4, W09D10.4

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PTC7
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP201_AA protein Get Run
CeleP201_AA_77-328 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0034914 PP2C-like 78-328 1.6e-35 115.5 In-house 19-289 (295) alignment
Range on Protein: 78-328
Range on HMM: 19-289/295.0
KDMLNGPSTVLDKGVFGDDAWFISR-----FKNTFVVGVADGVGGWRKYGIDPSAFSRRLMKECEKRVQKGDFDPQKPESLLDYAFRAS---------AE
  .  | ...  .    .||... .     .......||.||.||..   .  . . . |....|| ..  ....  .|. | .|| |          ..
lllrvgvasdqGrrksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallr

APRPVGSSTACVLVVHQEKLYSANLGDSGFMVVRNGKIVSKSREQVHYFNAPFQLTLPPEGYQGF------------IGDKADM----------------
  . ....||.|......||| ||.||| ....|||..|  .... ....  ..  | ..|.  .            .||   .                
pelagsGtTavvalirgnklyvanvGDSravllrngelvqltvdhkpvnelererilsaggavshgrvngvlavtRalGdfdlklllslllleplvsaeP

-ADKDEMAVKKGDIILLATDGVWDNLSEQQVLDQLKALDAGKSNVQEVCNALALTARRlafdskhnspfamkarehgflapGGKPDDITLVLLL
  .  |. ....|..|||.||.||.||.....| .. | |.  ...|....|.  | .                       .|. |.|| |.. 
dvtvleltledddfllLasDGlwdvlsneeivdivrsllakgldleeaaeeLvdlAla.......................rgsrDNiTvvvvr

PP2Cc_SM00332 82-208 1.2e-12 40.8 In-house 12-149 (274) alignment
Range on Protein: 82-208
Range on HMM: 12-149/274.0
NGPSTVLDKGVFGDDAWFISRF----KNTFVVGVADGvggwrKYGIDPSAFSRRLMKECEKRVQKGDFD--PQKPESLLDYAFRASAEAPRP--------
.| |.   . . . ||...       ... ..||.||     . | . . | .. . |. |.  |.. |   ...| .| .||..  |. .         
ygkssmqgwrksmeDahvvvvdlveeedwlffgvfDG.....hgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskele

--VGSSTACVLVVHQEKLYSANLGDSGFMVVRNGKIVSKSREQ
     |||.| ....|.|| ||.|||  ...||||.|. |...
nalsGstavvallkkedlyvanvGDSravlcrngkavqlsvdh

PP2C_2 Protein phosphatase 2C 89-267 6.8e-10 31.6 Pfam-A 7-188 (212) alignment
Range on Protein: 89-267
Range on HMM: 7-188/212.0
DKGVFGDDAWFISRFKNTFVVGVADGVGGWRkYGIDPSAFS-RRLMKECEKRVQKGDFD-PQKP-ESLLDYAF-------RA-SAEAPRPVGSSTACVLV
 || . .||..|.. ..  .. ||||.|  . ..   ...  . ...  || .......  ..  ....  .        .| .....    ..| ...|
rkgkpcqDalaireasdgwllaVADGaGsak.rSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllav

VHQEKLYSANLGDSGFMVV-RNGKIVSKSREQVHYF-NAPFQLTLPPEGYQGfigdkadmaDKDEMAVKKGDIILLATDGVWDNLSEQQVLD
.. ........||.. .|. |.|.. . . .... . |  . || . .. .          .  .. ...|| .|| ||||.|.|.... . 
itpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeel.........rirrlklepgdalllmTDGvsdslrkeepfr

PP2C_2 Protein phosphatase 2C 89-267 6.8e-10 31.6 In-house 7-188 (212) alignment
Range on Protein: 89-267
Range on HMM: 7-188/212.0
DKGVFGDDAWFISRFKNTFVVGVADGVGGWRkYGIDPSAFS-RRLMKECEKRVQKGDFD-PQKP-ESLLDYAF-------RA-SAEAPRPVGSSTACVLV
 || . .||..|.. ..  .. ||||.|  . ..   ...  . ...  || .......  ..  ....  .        .| .....    ..| ...|
rkgkpcqDalaireasdgwllaVADGaGsak.rSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllav

VHQEKLYSANLGDSGFMVV-RNGKIVSKSREQVHYF-NAPFQLTLPPEGYQGfigdkadmaDKDEMAVKKGDIILLATDGVWDNLSEQQVLD
.. ........||.. .|. |.|.. . . .... . |  . || . .. .          .  .. ...|| .|| ||||.|.|.... . 
itpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeel.........rirrlklepgdalllmTDGvsdslrkeepfr

subfamily_PPTC7_pd Subfamily PPTC7 91-329 4.1e-102 333.9 In-house 8-251 (252) alignment
Range on Protein: 91-329
Range on HMM: 8-251/252.0
GVFGDDAWFISRFKNTFVVGVADGVGGWRKYGIDPSAFSRRLMKECEKRVQKGDFDPQKPESLLDYAFRASAEAPRP-VGSSTACVLVVHQE--KLYSAN
  .|.||.|.|. |.. |.||||||||||..|||||.|||.|||.||| .........||..||..|.....|...| .||||||..|....  ||.|||
qkageDayfvsseksadvlgvADGVggWrsvGiDpsefsreLmkaceklskeskaeelkPvelleaayqelleekvpvlGssTacivvldksdkklesan

LGDSGFMVVRNGKIVSKSREQVHYFNAPFQLTLPPEGYQG-FIGDKADMADKDEMAVKKGDIILLATDGVWDNLSEQQVLDQLKAL-DAGKSNVQEVCNA
||||||.|||.||.| .|.|| |.||.|.||...|||..| .| ||...||. ..||||||||.|||||..|||.|...|..||.| .. ||..|.....
lGDSgflvvRkgkvvfrskeqqhkfntPyQLsiapegregkvildkpeaadsksfavkkgDiivlatDGlfDNlledeileilkelkeseksslqslakk

LALTARRLAFDSKHNSPFAMKAREHGFLAPGGKPDDITLVLLLI
|| .||.|..|....||||.||...|. | ||||||||.|. ..
laekarelsldpeyespfaqkakkngleasGGKpDDitvvvavv

0049733 PP2C-like 91-328 1.8e-37 122.0 In-house 15-232 (235) alignment
Range on Protein: 91-328
Range on HMM: 15-232/235.0
GVFGDDAWFIsrfkNTFVVGVADGVGGWRKYGIDPSAFSRRLMKECEKrvqkgdFDPQKPESLLDYAFRAS---------AEAPRPVGSSTACVLVVHQE
   ..||...    ......||||.||..  ..  . . . |......      ... ..| .|  ||.|          |. .. .. .||.|......
rkvneDavlv....glllfavaDGhgghaagevasellvetllellle......lllldleealrkaflaaneallelalaspelagmgtTavvalldgg

KLYSANLGDSGFMVVRNGKIVSKSREQVHYFNAPFQLTLPPEGYQGF---------IGDKADMADKDEMAVKKGDIILLATDGVWDNLSEQQVLDQLKAl
||| ||.||| ....|.||.|  .... .... ..|  . ..|.  .         .||    .|  .. ...||..|||.||.||.||.....| |.  
klyvanvGDsrayllrdgklvqltedhspvnelerqriitaggavrvpgrlaltralGdlllkpdvtvlelepgdflllasDGlwdvlsdeeivdllrs.

dagkSNVQEVCNALALTARRlafdskhnspfamkarehgflapGGKPDDITLVLLL
     ...|....|. .|..                       .|..|.||.|.. 
....ldleeaaerlvelala.......................rggrDNiTvvvvr

PP2C_SIG_SM00331 94-327 5e-20 65.0 In-house 17-215 (217) alignment
Range on Protein: 94-327
Range on HMM: 17-215/217.0
GDDAWFISRFKN-TFVVGVADGVGgwrkYGIDPSAFSRRLMKECEKRVQKGdfdpQKPESLLDYAFRASAEA-PRPVGSSTACVLVV--HQEKLYSANLG
. |  ..   .. .... ||||.|     |.. .|.|..| .  .. ...|    . ....|  . ||  |      .  |......   . ||. ||.|
sGDyydvvklnegrlllvvaDgmG....kGlaAaaassqlrtalrellseg....eelsqalkrlnraiyeekeekgmfaTlllalydfssgklsyanaG

DSGFMVVRNGKIVSKSREqvhyfNAPFQLTLPPEGYqgfigdkadmADKDEMAVKKGDIILLATDGVWDNLSEQQvLDQLKALDAGKSNVQEVCNALAL-
|| . ..|.|| | .  .     .....| | ||            .|  |. ..|||..||.|||.... ||.. ... .  .. ...|.. . .||  
dsrpyllrdgklveilkd.....vegaplGlepevs..........vdirelelekgdllllytDGltearsekg.faeerleeiledlvdseaqelaqk

---TARRLAFDSKHnspfamkarehgflapggkPDDITLVLL
    . .|| .|.                    .||||.|..
iveellelakgsng...................eDdiTvvvv

SpoIIE Stage II sporulation protein E (SpoIIE) 106-327 5e-16 51.1 Pfam-A 4-190 (193) alignment
Range on Protein: 106-327
Range on HMM: 4-190/193.0
TFVVGVADGVGgwrkYGIDPSAFSRRLMKECEKRVqKGDFDpqkPESLLDYAFRAS-AE---AprpVGSSTACVLV--VHQEKLYSANLGDSGFMVVRNG
.....|.|.||     |.. ......| .  .. . . . .   |. .|. . .|  ..   .   .   ||....   ...||. ||.|.. ...||. 
rlalvvgDvvG....hGleAalimgllrsalrela.tagle...paevlerlnealarnleee...erfatavlaeydpstgkleyanaGhpppllvrpd

KivsKSREQVHYFNAPfqLTLPPEgyqgfigdkaDMADKDEMAVKKGDIILLATDGVWDNLSEQQVL----DQLKALD--AGKSnVQEVCNALALTARRl
.   . ... . ...|  | . ||            ... |. ...||..||.|||| .. .... |    ..|..|.  .|.| ..|...||  .... 
g...gtkfllvstglp..lGilpe..........adyeeaelqlepgdllllyTDGvtEardpdgelfgkerllallaeaeges.leelldalveelle.

afdskhnspfamkarehgfLAPGGKPDDITLVLL
                   |  |.. |||||..|
...................lgsgeleDDitllvl

SpoIIE Stage II sporulation protein E (SpoIIE) 106-327 5e-16 51.1 In-house 4-190 (193) alignment
Range on Protein: 106-327
Range on HMM: 4-190/193.0
TFVVGVADGVGgwrkYGIDPSAFSRRLMKECEKRVqKGDFDpqkPESLLDYAFRAS-AE---AprpVGSSTACVLV--VHQEKLYSANLGDSGFMVVRNG
.....|.|.||     |.. ......| .  .. . . . .   |. .|. . .|  ..   .   .   ||....   ...||. ||.|.. ...||. 
rlalvvgDvvG....hGleAalimgllrsalrela.tagle...paevlerlnealarnleee...erfatavlaeydpstgkleyanaGhpppllvrpd

KivsKSREQVHYFNAPfqLTLPPEgyqgfigdkaDMADKDEMAVKKGDIILLATDGVWDNLSEQQVL----DQLKALD--AGKSnVQEVCNALALTARRl
.   . ... . ...|  | . ||            ... |. ...||..||.|||| .. .... |    ..|..|.  .|.| ..|...||  .... 
g...gtkfllvstglp..lGilpe..........adyeeaelqlepgdllllyTDGvtEardpdgelfgkerllallaeaeges.leelldalveelle.

afdskhnspfamkarehgfLAPGGKPDDITLVLL
                   |  |.. |||||..|
...................lgsgeleDDitllvl

PPM_PTC7_SpoIIE 107-326 3.5e-18 59.3 In-house 33-226 (230) alignment
Range on Protein: 107-326
Range on HMM: 33-226/230.0
FVVGVADGVGgwrkYGIDPSAFSRRLMKECEKRVqKGDFDpqKPESLLDYAFRASAEAPRPV---GSSTACVLVVHQEK--LYSANLGDSGFMVVRNGKI
 .. |.|..|     |.. ......| .  ...  . ...  ||| .|  ...| | . .     . .||.|.... ..  || ||.||| ...||... 
lalvvgdvdG....hGgraalamgllrtalrela.fagle..kpeeilrrlnlalaadledepsssgaTavvalidpstgklyvanaGdsppllvrddgg

vskSREQVHYFNAPFqLTLPPEgyqgfigdkaDMADKDEMAVKKGDIILLATDGVWDNL--SEQQVL----DQLKALDAG---KSNVQEVCNALALTARR
    ||..  ...|  | . |.            ... ... ..||..||.|||| ..   ...  |    . | ....|   . . ||.. ..  .  .
...ererivagglps.lGilpg..........rvfgvlavslapGdllllytDGvveaepdtsdgelfgkdeflilasdglwdvlspqelvdlvrdelek

LafdskhnspfamkarehgfLAPGGKPDDITLVL
.                   .| |.. |||||. 
p...................aaeglleDDitllv

subfamily_PPM1E_pd Subfamily PPM1E 108-202 2.4e-06 20.0 In-house 42-135 (265) alignment
Range on Protein: 108-202
Range on HMM: 42-135/265.0
VVGVADGVGGwrkygIDPSAFSRRLMKECEKRVQKGDFDPQK----PESLLDYAFRASAEAPRPVGSSTACVLVVHQEKLYSANLGDSGFMVVRNGKIV
. .| || ||     .. . .. . ..| . | .|   ||..       |.| .| . ||  .  . ||| | ......|| | ||||  ..||.|..|
ffavfDGHgG.....veaakyaaahlhellvrqeklkedpaealkeafkltDerflqkaereklksGstavvvliekdqlyvaWlGDsqallvrkgeav

PPM_PTC7 116-202 1.8e-09 30.4 In-house 32-134 (259) alignment
Range on Protein: 116-202
Range on HMM: 32-134/259.0
GGWRKYGIDPSAFSRRLMKECEKRVQ-----KGDFDPQ-KPESLLDYAFRA--SAE---------APRPVGSSTACVLVVHQEkLYSANLGDSGFMVVRN
  .. ...  ....|.. | .....      . .|..  |.|  |  .|.|   .|         .|  .||.  ..|..... || ||.|||.....|.
dsvaffavfdghggreaakyarehleeilkerksfeeleklekalrksflaldtdeelksseantepstsGstAvvalitgsk.lyvAnvGDSravLcrs

GKIV
|..|
gnav

PP2C Protein phosphatase 2C 155-202 8.7e-08 25.0 Pfam-A 85-133 (255) alignment
Range on Protein: 155-202
Range on HMM: 85-133/255.0
DYAFRAS---AeAPRPVGSSTACVLVVHQEkLYSANLGDSGFMVVRNGKIV
|. .. |   . .|  .||.  ..|..... || ||.|||  ...|.....
deelksskant.epsksGstavvalirgkk.lyvAnvGDSravLcrkdnak

PP2C Protein phosphatase 2C 155-202 8.7e-08 25.0 In-house 85-133 (255) alignment
Range on Protein: 155-202
Range on HMM: 85-133/255.0
DYAFRAS---AeAPRPVGSSTACVLVVHQEkLYSANLGDSGFMVVRNGKIV
|. .. |   . .|  .||.  ..|..... || ||.|||  ...|.....
deelksskant.epsksGstavvalirgkk.lyvAnvGDSravLcrkdnak

subfamily_ILKAP_pd Subfamily ILKAP 155-199 7e-06 18.4 In-house 97-143 (293) alignment
Range on Protein: 155-199
Range on HMM: 97-143/293.0
DYAFRASAEAPRP--VGSSTACVLVVHQEKLYSANLGDSGFMVVRNG
|  | . |.. .|     ||| |..| .. ||.||||||  ..||. 
deefLklaskakPvWkdGstatvvlvldnvlyvanlGdskavlvrkk

subfamily_PPM1H_pd Subfamily PPM1H 158-207 1.7e-06 20.1 In-house 151-200 (404) alignment
Range on Protein: 158-207
Range on HMM: 151-200/404.0
FRASAEAPRPVGSSTACVLVVHQEKLYSANLGDSGFMVVRNGKIVSKSRE
 .   || |  |  ||.| .| ..||| || |||  ..||...|.  |..
iarereayrikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsad

subfamily_PPM1G_pd Subfamily PPM1G 165-205 7.5e-06 18.2 In-house 292-332 (473) alignment
Range on Protein: 165-205
Range on HMM: 292-332/473.0
PRPVGSSTACVLVVHQEKLYSANLGDSGFMVVRNGKIVSKS
|     .||.| .....||. || |||  .. |||| .  |
pGedsGttAvvaLlkekklivAnaGDsRcvlsrnGkAldls

subfamily_PPM1A_pd Subfamily PPM1A 170-204 8e-06 18.4 In-house 116-150 (282) alignment
Range on Protein: 170-204
Range on HMM: 116-150/282.0
SSTACVLVVHQEKLYSANLGDSGFMVVRNGKIVSK
 ||| ...|....|. ||||||  ...|||| . .
GsTavtvlvsekhliianlGDsRavlcrngkaafl

subfamily_CG9081_pd Subfamily CG9081 180-263 4e-07 20.4 In-house 105-191 (195) alignment
Range on Protein: 180-263
Range on HMM: 105-191/195.0
QEKLYSANLGDSGFMVV-RNGKIVSKSREQVHYFNAPFQLTLPPEGYQGFIGDKADMADK--DEMAVKKGDIILLATDGVWDNLSEQ
|  |.....|||  .|  .. | |     ..|  .   .  |.       || ..|. .     ..|..|||..| .||| ||.  .
qWglfvvsvGdspvfvyspdnksvrevtvashskdgirdvrlsGGalGpaiGtdpdlenlslsylpvaeGdivfltsdGvsdnfdPv

subfamily_Sponge-PPM-1_pd Subfamily Sponge-PPM-1 203-263 1.9e-06 17.6 In-house 130-192 (199) alignment
Range on Protein: 203-263
Range on HMM: 130-192/199.0
SKSREQVHYFNAPFQLTLPPEGYQGFIGDKADMADK--DEMAVKKGDIILLATDGVWDNLSEQ
 .   ..|  .   .  |        || ..|. .     . |..|||.|| |||. ||.. .
heatvachdkdGirtarlsGGalGpaiGtdpdlenlslsylpvaeGdivllttdGisdnfapv

PPM_PTC7_SpoIIE_motif 237-327 3.6e-12 39.8 In-house 3-78 (81) alignment
Range on Protein: 237-327
Range on HMM: 3-78/81.0
DKDEMAVKKGDIILLATDGVWDNLSEQQVL----DQLKALD--AGKSnVQEVCNALALTARRlafdskhnspfamkarehgfLAPGGKPDDITLVLL
|  |  .|.||..||.|||.... ...  |    . |...|   |||  ||.. .|  ....                    .. |.. |||||..|
deaefqLkpgdvllLyTDGltEardsdgelfgkeellrladraegks.lqeladklvdevle....................ngsgereDDitllvl

PP2Cc_SM00332 243-326 9.1e-10 31.4 In-house 210-273 (274) alignment
Range on Protein: 243-326
Range on HMM: 210-273/274.0
VKKGDIILLATDGVWDNLSEQQVLDQLKALDAGKsnvqevcnalaltarrlafdsKHNSPFAMKAREHGFLAP-GGKPDDITLVL
 .......||.||.||.||.|.| | ...| | .                     |.|.| .. ..    ... ||. |.|| |.
tsedeflilaSDGlwdvlsnqevvdivrkllakg.....................ktndpqeaaelldeeairrggseDniTvvv

subfamily_PPM1G2_pd Subfamily PPM1G2 244-287 4.3e-06 18.9 In-house 218-261 (287) alignment
Range on Protein: 244-287
Range on HMM: 218-261/287.0
KKGDIILLATDGVWDNLSEQQVLDQLKALDAGKSNVQEVCNALA
.. . ..|| ||.|| |....|.| ..   . . ...|... | 
eddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieell

subfamily_PPM1A_pd Subfamily PPM1A 245-290 1.4e-06 20.9 In-house 219-264 (282) alignment
Range on Protein: 245-290
Range on HMM: 219-264/282.0
KGDIILLATDGVWDNLSEQQVLDQLKALDAGKSNVQEVCNALALTA
. | ..|| ||.|| ||...|..  .     .....||..||  .|
eddflvlacDGiwDvlsdeevvelvrkrlevadeleevakalvdka

PP2C Protein phosphatase 2C 247-291 8e-06 18.6 Pfam-A 203-247 (255) alignment
Range on Protein: 247-291
Range on HMM: 203-247/255.0
DIILLATDGVWDNLSEQQVLDQLKALDAGKSNVQEVCNALALTAR
. ..||.||.|| ||.|.. |  .     |.. .|....|.  | 
efliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeai

PP2C Protein phosphatase 2C 247-291 8e-06 18.6 In-house 203-247 (255) alignment
Range on Protein: 247-291
Range on HMM: 203-247/255.0
DIILLATDGVWDNLSEQQVLDQLKALDAGKSNVQEVCNALALTAR
. ..||.||.|| ||.|.. |  .     |.. .|....|.  | 
efliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeai

PPM_PTC7_motif 250-294 7.1e-09 29.0 In-house 1-46 (51) alignment
Range on Protein: 250-294
Range on HMM: 1-46/51.0
LLATDGVWDNLSEQQVLDQLKAL-DAGKSNVQEVCNALALTARRLA
.||.||.||.||.|.. |...   .. .   ||... |. .|.  .
iLAsDGLWDvlsdqeavdlvrdqlskkglspqeaAeklvdealarg