Gene ZK354.9 in Caenorhabditis elegans

Synonym: CELE_ZK354.9, CELE_ZK354.9

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily CelePPP-sf4
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP235_AA protein Get Run
CeleP235_AA_22-291 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPZ_pd Subfamily PPZ 4-285 6.4e-100 327.5 In-house 19-296 (300) alignment
Range on Protein: 4-285
Range on HMM: 19-296/300.0
RRRVVCLRARARPQSLRRRRtcNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFML
| . |||.     |   . |  ..|  || |.| . ...| ||.|||..|||||| | |||  ||||||||||||||..|||||||..||. .|. ||.|
rtknvclknseilqicikar..elflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffll

RGNHECSLINKIYGFYDECQRRYNKpSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPnTLAIDILWSDPTNFQKGWNPN
||||||. . ..|||||||.|| |   .. .|   |  .||.|.|  .|.|.|||.| .|... ..| . || | |.   |  |.||||||. .. |. |
rgnhecanvtrvygfydeckrrcni.kiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdf.glindllwsdptdssnewedn

SRGVSYVFGSDALRKLLDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPRKK
 |||||..   |. |.|... .|||.||| ||.|||||| .| |||.|||| |||.|||  ||| |.. |.||| .| |   
ergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfelldplds

subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 23-293 4.7e-200 655.8 In-house 14-284 (284) alignment
Range on Protein: 23-293
Range on HMM: 14-284/284.0
RTCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDEC
....||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||
hafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiygfyeec

QRRYNKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDR
||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
qrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgsdalrklldr

LQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPRKKIARRRMMP
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlrprkkiarrrmmp

PP2Ac_SM00156 23-283 8e-116 378.8 In-house 12-270 (271) alignment
Range on Protein: 23-283
Range on HMM: 12-270/271.0
RTCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDEC
....|......|.|...|. ..||||||..|||||....|.|.. .|.|||||||||....|.||||||.|...|.....||||||.| .||||||..|.
evkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssvnkiygfeeev

QRRYnKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRpFDNPEPNTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDR
.|.| . ..|  || .|| .||.|||...|||||||.|..|......| .|| ..... ..|.||.|||||.. .||..|..||.|.|||.||....|..
krky.gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkr.vkekpeegllidllwsdpeqkekgfqpskrglsvvFgedavkeflkk

LQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPR
....|..|||.||..||||||...|||||||| ||..|.|.|||. |.||| .|...|.. 
nnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlkeq

subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 23-282 4.2e-101 331.1 In-house 19-282 (284) alignment
Range on Protein: 23-282
Range on HMM: 19-282/284.0
RTCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFP------HRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIY
|. ..| |... .| ..|..|.||||||| ||| |.| ||.|      .  .||||||||||| . .| |.||||||...|.. |.||||||   .|. |
rarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrgnhesrpvnmqy

GFYDECQRRYNKpSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNtLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDAL
||| ||..|| . ..| .|.  |  |||.|.|...|.|||||.|. | .. || ...||.| |.   .  |. |.|| .  .|..   ||   |||..|.
gfyleckkryse.alyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdig.viadltwadpeaevegykesprgagkvfgakav

RKLLDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRP
...|.. ..||||||||||.|||||||.|.||||||||.||||.||.|||. |...||.||.||.|
keflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlkp

0045823 Metallo-dependent phosphatases 23-291 2.6e-99 326.0 In-house 54-332 (473) alignment
Range on Protein: 23-291
Range on HMM: 54-332/473.0
RTCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDEC
....|..|.|.|.| . .| ..||||||. |||||..|.|||.  ...||||.|||| . ||...||.|.|. .|...|.||||||. |.| .|||.||.
eakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkikypgnvfllrGNHElrllnglygfgdet

QRRYNKPsVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEpNTLAIDILWSDPtNFQKG--------WNPNSRGVSYVFGSD
 ..|. . .|  |  ... .||.|..|..||..|||.|  |....|.|.|.||.. |. . |. |.|||||   ..|        . .. ||..|.|| |
lekyged.lyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipd.dgllldllwsdP.weddgdgllrlrffgnsprgagylFgpd

ALRKLLDRLQIDLVVRAHQVVQDGYEFFANRR------LVTIFSAPFYCGQFDNAAAVMYVNKNLvCSFVVLRPRKKIARRRM
|....|.. ..||.||.|..|..|||.. ...      ..|.|||| |||...| |||......| .||....| .   .. .
aveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsphplilpl

PPP_3 23-280 2.4e-96 314.9 In-house 13-269 (271) alignment
Range on Protein: 23-280
Range on HMM: 13-269/271.0
RTCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDEC
.. .|..|...|.| ..|...|||||||. |||.||.. |.... .||||||||||||. ||..|||.|.|. .|.....||||||.. |||.|||..|.
klkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrqinkvYgFkkev

QRRYNKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEpNTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDR
...... .||  .. ||. .||.||. ...|..|||.|. .....|.. ..|. . || ... .| |.|.... ..|.....||....||.|. ...|..
lkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpe.egklldlllssdpekeeglenskrGagllFgpdvteeflek

LQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVL
 ...|..|||.....|||.......||.|||| ||....||.|.. ....| ..|..|
nkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkql

0049330 Metallo-dependent phosphatases 23-288 3.7e-96 314.8 In-house 41-304 (309) alignment
Range on Protein: 23-288
Range on HMM: 41-304/309.0
RTCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDEC
....|. ..|.|.| . .| ..||||||. |||||..|.|||   ...||||.|||| . ||..|||.|.|. .|...|.||||||. |.| .|||.||.
kakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalkllypdnvfllrGNHElrllnglygfgdet

QRRYNkPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPnTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDR
.|.|. ....  |  ... .||.|..|..|||.|||.|  |....|.|...||.. |.   |  |.|||||... .|. || ||...||| .|....| .
lrkyg.aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipld.gllcdllwsdplpiregfapnprglgvvfghtaverflkk

LQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPRKKIAR
...||..|.|..|..||..|....|.|.|||| |||...|..||......||.||....| . . .
ngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvpllll

0053225 Metallo-dependent phosphatases 23-283 1.6e-88 289.9 In-house 33-291 (293) alignment
Range on Protein: 23-283
Range on HMM: 33-291/293.0
RTCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDEC
 ...|. |.|.|.| . .| ..|||||.. |||.|..| |||.  ...||||.|||| . ||...||.|.|. .|.....||||||. |.| .|||.||.
eakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkllypdnvvllrGNHElmllnglygfgdet

QRRYNKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNtLAIDILWSDPTnFQKGWNPNSRGVSYVFGSDALRKLLDR
 |.|   ...  .  ... .||.||.|..||..|||.|  | ...|.| |.||.. |. . |  |.|||||. . .|| |. ||...||| .|....|..
lrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplripleg.llldllwsdpd.lwsgwlpsyrglgvvfghtavlrflkk

LQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPR
 ..||..|.||||.|||... ...|||.|||| |.|...|..||......||..|....|.
ngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfapv

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 23-66 1.5e-12 40.4 In-house 20-63 (317) alignment
Range on Protein: 23-66
Range on HMM: 20-63/317.0
RTCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHR
|. ..| |.|. .| ..|. |.||||||| ||| |.| ||.|. 
rarelfwkeplkleleapvtivGdihGqfedllalldlnGwpls

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 23-65 1.2e-08 27.5 In-house 22-64 (339) alignment
Range on Protein: 23-65
Range on HMM: 22-64/339.0
RTCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPH
|. ..   .|.... ..|| . ||||||| ||| ..| ||.| 
rareliwsepiflkleapicvmgdihgqfddllamldmngwpl

subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 24-286 6e-152 497.8 In-house 36-297 (298) alignment
Range on Protein: 24-286
Range on HMM: 36-297/298.0
TCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQ
. .||.||..|.| ..||..|||||||.|||||||||.|||..|||||||||||||...||.|.||.|||| .||.||.|||||||..||..||||.||.
akkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnffllrGnheceainrvyGfyeeck

RRYNKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPnTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDRL
|||.. ..| .|..||. .|||||.|.||||||||.||.|....|||..|||||..|. .||||.||.||.|..|||..||||||.|||.|....||..|
rrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskee.slaidllwadpenavkgwaensrGvsvvfGedvvkdllekl

QIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPRKKI
.|||||||||||||||||||...||||||||.|||||||.||||.|...||.||.||.|.||.
didlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkpekke

subfamily_PPP1C_pd Subfamily PPP1C 24-285 3.6e-120 393.4 In-house 22-281 (282) alignment
Range on Protein: 24-285
Range on HMM: 22-281/282.0
TCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQ
. .|. .||.|.| . |..|.||||||..||||||...|.| ..|||||||||||||. ||||.||.|||. .|...|.||||||.. ||.||||||||.
areillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesasinriyGfydeck

RRYNKPsVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPnTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDRL
|||..  .. .|  ||. .||.||| ..|||.|||.|. |....|.| |.|| . ||  .|..|.||||| . ..||. |.||||..||.|...|.| . 
rrysik.lWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpek.gllcdllWsdpdkevlgwsendrGvsftfgkdvvekflqkn

QIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPRKK
..||.|||||||.|||||||.|.|||.|||| |||.||||.||. |...|..|| .|.|.||
dldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilkpakk

PPP_1 24-268 4.8e-91 297.7 In-house 13-263 (264) alignment
Range on Protein: 24-268
Range on HMM: 13-263/264.0
TCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQ
. ...||...|.| ...| .|||||||| |||.|| . |.... |||||||||||||. .|..|||.|.|. .|...|.||||||.. ..|.|||..|..
lkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqvtkvygFkkEvl

RRYNKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLAI------DILWSDPTNFQKGWNPNSRGVSYVFGSDALR
... . ..|  .. ||  .||.||. ..||..|||.|..|. . | | ..|  . ||  .|        |||.||... ..... . ||..|.||.|. .
kkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRGagylfgkdvte

KLLDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMY
|.|.. ...|..|||.|...||||...|..||||||. |. ...|..|.. 
kflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvk

subfamily_PPP3C_pd Subfamily PPP3C 24-273 1.9e-74 244.1 In-house 53-313 (452) alignment
Range on Protein: 24-273
Range on HMM: 53-313/452.0
TCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQ
......|.. |.| ..|| ..||||||| |||.||. .| |. ..||||||||||| . .|..| |.| |. .|...|.|||||||  . . . | .||.
aakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecrhlteyftfkeeck

RRYNKpSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRpFDNPEPNTLAIDILWSDPT-NFQK-----GWNPNS-RGVSYVFGSDAL
 .|.. .|| ..   |  .||.||. |. ||.|||.|  .... ... ..| | .|.   .  |.|||||. ....      . ||| || ||...  | 
ikyse.evydacmesfdslPlaallnqqflcvhGGlspeikslddikkldr.fkeppasGplcdllWsdPledygeekteekfvpnsvrGcsyfysykav

RKLLDRLQIDLVVRAHQVVQDGYEFFAN------RRLVTIFSAPFYCGQFDNAAAVMYVNKNL
 ..|.. ..  ..|||.. ..||. . .        |.|.|||| |.. ..| |||. ...| 
ceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennv

subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 25-283 6.8e-116 379.3 In-house 19-275 (280) alignment
Range on Protein: 25-283
Range on HMM: 19-275/280.0
CNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQR
 .|.  |  ..| ..|...|||.|||..||||||.. .||   ||||||||||||.. || ||||.|||| .||.|..||||||.  ||. |||.||..|
kkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevisinrkygfkdevkr

RYNKpSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEpNTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDRLQ
||.. ..|  |. ..  .||.|||. ||||||||.|. |. ...|. ..||||... ..|| |.||.|| | . ||  ||||||..||.. ...| ..|.
rysl.alynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsed.eclamdllwadpenkvtgwaensrgvsvifganvvkdltekld

IDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPR
|||..| ||||||||||||...|||.|||| |.|.|||.|||. |...|. || ||.| 
idliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkpa

subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 25-283 2.4e-104 341.7 In-house 36-295 (297) alignment
Range on Protein: 25-283
Range on HMM: 36-295/297.0
CNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQR
 ..|..|  ..| |.||..|||||||| |||||| . |.|  |||||||||||||.  .|||.||.|||| ||  .|.||||||| ..||.||||.|||.
ldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhecefvnkvygfyeecqk

RYNKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQ---NVSQLRAIKRPFDNPEpnTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLD
||.   .|..|. ||  .||| |. ..|||||||.| .|     .  || |.|. .  |  .|  |.||.||     |.  | ||    || ||. ||  
ryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkierstegke..rlvadllwadpisglsgfmenqrgagcgfgrdavlklcs

RLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPR
 ...|||.|||||||||||||| |.|||||||| |||||||.||.| ....| ||| .||| 
efkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeilrpt

subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 25-282 1e-83 274.1 In-house 19-274 (280) alignment
Range on Protein: 25-282
Range on HMM: 19-274/280.0
CNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQR
  || ..  |.||..||.. |||| |. |. ||||  |     . .||||||||| . .| ..|||. |. . .. ..||||||   .||||||| ||| 
eaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnkiygfyvecqy

RYNKpSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDnPEPNTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDRLQ
.|    ..  |. .|  ||...|. .|.||||||.|  | |.  .| | || . |    | ||.|||||||  .||  . ||.||.||   . .    |.
kygv.glwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpce.pldrgllidllwsdptnkgegwfhsirgisymfgkgvveqacksle

IDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRP
|||..|||||||||||..| |||.|.|| | || || |||||. .| ||  ||  | |
idliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqlip

subfamily_PPP2C_pd Subfamily PPP2C 25-282 8.5e-79 257.7 In-house 30-285 (290) alignment
Range on Protein: 25-282
Range on HMM: 30-285/290.0
CNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQR
 .|..|.  . | ..|. .|||.|||| ||| ||   |    .|||||||||||| . .||. || | || ...   .||||||   | ..||||||| |
keilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqitqvygfydeclr

RYNKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLAiDILWSDPTNfQKGWNPNSRGVSYVFGSDALRKLLDRLQ
.| ...|.  |  .|  .|||||| ..|.|.|||.| ... . ..||..|  . |.  .|. |.||||| . ..||.   ||  | || |  .|. .. .
kygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplc.dllwsdpdd.rggwgisprgagytfgkdisekfnktng

IDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRP
. |..||||.| .||..  .|..||||||| || .  | ||.. ....|  ||.   |
ltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdp

subfamily_PPP6C_pd Subfamily PPP6C 25-273 5.5e-73 238.6 In-house 28-274 (290) alignment
Range on Protein: 25-273
Range on HMM: 28-274/290.0
CNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQR
.... ..  .   .||. .|||||||| ||. || . |    ..|.||||.|||| . |||. .|.. |. .|..  .||||||.  | ..|||||||..
ldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqitqvygfydecln

RYNKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLAiDILWSDPTNFQKgWNPNSRGVSYVFGSDALRKLLDRLQ
.| . ...  .  ||  ....|.. ...||.|||.|  .. . |.| |.|  . |.  ... |..|||| . .. |.  .||  |.|||   ....   .
kygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafc.dlvwsdpedvet.wavsprgagylfgskvtkefvhinn

IDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNL
..|..||||.|..|.... . .|||..||| || .  | |... .... 
lklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledae

subfamily_PPPLV_pd Subfamily PPPLV 25-272 2.1e-54 177.8 In-house 10-279 (290) alignment
Range on Protein: 25-272
Range on HMM: 10-279/290.0
CNIFNKQPMLIEANSPINICGDIHGQFSDLLrLFDKN----GF-PHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFY
 .|. ..  |.| .||. . ||.||.. ||   |.|     |     |..||||||||||.. .| |  |.| ||..| ....||||||   . . . ..
vdilaaeerllelksptyvlgdlhgnyrdli.yfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvqesieyk

DECQRRYNK--PSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQL---RAIKRPF-DNPEPNTLAIDILWSDPTN-----------FQKGWNP
 |.. .. .   .|. .|  ||  .||.| . ....|.|.|. .  .  ...   . |   . |. .   ||.||||||| .            ..|. .
gegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvlneGfvd

NS-RGVSYVFGSDALRKLLDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKN
|. || ..||..||| ..| | ... |.|||.| . |...  . ||.|.||.  |||. ..|| ..  .|.
ndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssneaalilvdkkk

subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 26-287 3e-124 407.1 In-house 38-298 (299) alignment
Range on Protein: 26-287
Range on HMM: 38-298/299.0
NIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRR
..| .|. |.| ..|| .|||||||.|||||.|||.|||  .|.||||||||||.  ||.| ||...|. .|..||||||||||  ||..||||.||..|
svfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhecpainrvygfyeecnkr

YNKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPnTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDRLQI
|.   ... |.  |. |||| |.| ||||||||.|  ||.. ||| . || | |.| .| ||.||.|| .. |.| .| |||||||| | ... ..||.|
ykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnp.slgidllwadpdqsvkdwlanvrgvsyvfgqdvvadvisrldi

DLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPRKKIA
||| ||||||||||||||...|||||||| |||||||.||.| |..||||.||||.| .| .
dlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptpksl

subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 26-285 6.7e-99 323.4 In-house 24-284 (287) alignment
Range on Protein: 26-285
Range on HMM: 24-284/287.0
NIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRR
.|..  | |.| ..||.|.||||||. ||||.|.. | . . .||||||||||| . || .||||..|. .|..  .||||||.  |||.|||..| .|.
eileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevkkinklyGfkeelkrk

YNkPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEP-NTLAIDILWSDPTNFQKGWNPN-SRGVSYVFGSDALRKLLDRL
..  ..|  |. |||..|| | |..||||||||.|. |. . .|.|.|.|  . .  . | .|.||.||.. .|. ..|  |..| |||   . .|| .|
rq.erlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllkkl

QIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPRKK
.|||.||||.|...||.|....||||.||||.|.|.  | .||. |.| |  |||||.| . 
didlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpedf

subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 26-283 4.9e-89 291.3 In-house 22-277 (281) alignment
Range on Protein: 26-283
Range on HMM: 22-277/281.0
NIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRR
 || ..  |.|...|| . ||.|.|| || |||.  | . .  ..|||||||||...||...|||..|. .... ..|||||| . .||||||| ||. .
aifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasvnkiygfyvecvtk

YNKpSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEpNTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDRLQI
| .  ... |.  |  .|..||. .|.||||||.|  | .  .|| . .| .|..   | ||.||.||.|  ..|   |||.|..|| . . .   ||..
yGe.elwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnld.rGlviDllwadpdnkveewkassrGssftfGknvvddvckrlev

DLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPR
.|..||||||||||| .. |.|.|.||.| || .. |||||. |...|  |.| | | 
eliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislvalvpa

subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 26-284 4.2e-83 271.7 In-house 30-290 (290) alignment
Range on Protein: 26-284
Range on HMM: 30-290/290.0
NIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRR
.|..  | |.| ..|| | ||||||. .||| ||. |.| . ..|||||||||| . ||  |||| ||. ....  .||||||.  .|..|||..|  |.
eileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhevrkvnrlygfkeelark

YNKpSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEP-NTLAIDILWSDPTN-FQKGWNP-NSRGVSYVFGSDALRKLLDR
 .   ..  .. ||....| | ||..|||||||.|. ..    |.|.|.|  . .  . | .|.||.|||.  ..  .    |..| ||| ..| .|| .
rgs.rlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkqraisvvfgkkglddllkk

LQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPRK
| ..|.||||.| ..|..|  ...|||.||||.|.|.  |  |.. | . |  |.|||.|||
lalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlkprk

subfamily_PPP4C_pd Subfamily PPP4C 26-280 5.3e-81 265.0 In-house 30-282 (288) alignment
Range on Protein: 26-280
Range on HMM: 30-282/288.0
NIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRR
.|. ..  . . .||. .|||||||| |||.||. .|  .  |||||||.||||.. .||.||| |.|| .|..  ..|||||.  | ..||||||| |.
eilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqitqvygfydeclrk

YNKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLaIDILWSDPTNFQkGWNPNSRGVSYVFGSDALRKLLDRLQI
| . .|.     ||  ..|.|.. ..|.|.|||.|  .... ..|.| |  . |.  .| .|.||||| . . ||.   ||  |.||||.  .. .. .|
ygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegpl.cdllwsdpedae.gwavsprgagylfgsdvveqfneandi

DLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVL
.|..||||.|..|| .  |....|..||| || .  | ||.. ....|   | ..
elicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkif

subfamily_PPP5C_pd Subfamily PPP5C 26-273 1.6e-75 247.1 In-house 48-299 (322) alignment
Range on Protein: 26-273
Range on HMM: 48-299/322.0
NIFNKQPMLIEANS----PINICGDIHGQFSDLLRLFDKNGFPHRA-NYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYD
....|.| |.| .      . .|||||||| ||| .|..|| | .   ||| ||.|||| . .|.||.|...|...|||||. ||||| . .||.||| .
ellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrGnhesdnmnklyGfeg

ECQRRYNKpSVYVSFEGVFSDMPLTALVGQRILCMHGGVS-KMLQNVSQLRAIKRPFDNPEPNTLaIDILWSDPTNfQKGWNPNSRGVSYVFGSDALRKL
|.. .|..  |.  |  ||. .||. .. ...| .|||.  .   ....|| |.|  ..|| ..| ...||||| . ..| .| .|||.  || |  .|.
evkakyte.kvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegll.vellwsdpqe.anGrspskrGvgvqfGpdvtkkf

LDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYV-NKNL
|.  ...|..|.|.| ..|||.  . .|.|.|||| || | .| .|.. . ...|
lkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddl

subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 26-284 1.5e-74 243.9 In-house 20-301 (302) alignment
Range on Protein: 26-284
Range on HMM: 20-301/302.0
NIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKN----------GFPH-RANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINK
. ..|.  |.|  .|. | ||||||| ||.|.. ..           . . .  ..|||||||||.. .| | |.||.||..|... .||||||.  || 
ellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyillrgnhetkainf

IYGFYDECQRRYNKPS---VYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLAIDILWSDPTNFQKGW--------NP-
 ||| .| . |. |     ..  |. ||| |||.||||..|||.|||.|. |. . ... ||||. .  ...|| |.|..||...|.          .  
aygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqllaavsekPkyakn

NSRGVSYVFGSDALRKLLDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPRK
. ||.|.||   |.|..  ||...|.|||||..  |. |||...|.|||||| |  . ||  ||. |. |   |  |||..|
ivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrnkk

subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 26-283 4.9e-74 242.2 In-house 21-301 (302) alignment
Range on Protein: 26-283
Range on HMM: 21-301/302.0
NIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKN----------GFPH-RANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINK
. ..|.  |.|  .|. | ||||||| ||.|.. ..           . . .  ..|||||||||.. .| | |.||.||..|... .||||||.  || 
ellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyillrgnhetkainf

IYGFYDECQRRYNKPS---VYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLAIDILWSDPTNFQKGW--------NP-
 ||| .| . |. |     ..  |. ||| |||.||||..|||.|||.|. |. . ... ||||. .  ...|| |.|..||...|.          .  
aygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqllaavsekPkyakn

NSRGVSYVFGSDALRKLLDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPR
. ||.|.||   |.|..  ||...|.|||||..  |. |||...|.|||||| |  . ||  ||. |. |   |  |||..
ivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrnk

subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 26-283 9.2e-67 218.4 In-house 34-292 (307) alignment
Range on Protein: 26-283
Range on HMM: 34-292/307.0
NIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRR
 ||  .  |.. . |  . ||.|||| ||. .|   | |  . |.| |||||||  .||.|||||.||...|..  .|||||| . .|| ||||.||   
tifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnkkygfyeecvts

YNKP--SVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEpNTLAIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDRL
  |    ..  |. .| ..|..||.  .|||||||.|  |  . .||   .|  ||    .  |.||.||      |.  |||  . ||.. .  .  ||
ipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpf.rgivndmlwadpdpsvfewkassrgsgftfgtnviddvckrl

QIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPR
 ..|..||||.. |||  .. |.|.||||||.||  . || .|. |.. |    | . | 
gveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgiqlvafvpe

subfamily_PPG1_pd Subfamily PPG1 30-278 3.8e-62 203.2 In-house 32-291 (300) alignment
Range on Protein: 30-278
Range on HMM: 32-291/300.0
KQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRRY-NK
|.  .|| .||. . ||.|||| |.| .|.  |    .|||||||||||| . .||| || . |. .|    .||||||   | ..|||| || |.|  .
kesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhesrqitqvygfyteclrkyggn

PSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLAiDILWSDPT---------NFQKG--WNPNSRGVSYVFGSDALR
. |.  .  .|  . |.|.. . | |.|||.|   . . |.. . |  . |.  .|| |.|||||            ..|  .    ||  | .| |   
srvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegala.dllwsdpeennnptldhpdregqhfvvsqrgagysygkdvve

KLLDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFV
|.|   ... ..||||....||. . . .| |..||| || .  | |... .....   | 
kflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfn

subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 34-289 1.3e-85 280.3 In-house 2-262 (263) alignment
Range on Protein: 34-289
Range on HMM: 2-262/263.0
LIEANSPINICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRRYNKP----
|.| ..||||||| |||. ||||.|.  |   ...||||||||||| | || |.|||. |. .| ....||||||   ||| |||. | ..|...     
llelqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevye

SVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLAIDILWSDPTNFQKGWNPNS-RGVSYVFGSDALRKLLDRLQIDLV
|||  |. ||| ||| |.| .||||||||.|  |... ..|||  |..  .   || |.||.|| .  ||..||  | .| |||   .  |  ||.|||.
svynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidli

VRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPRKKIARR
|||||||. || |||.|||.|.|||  |  .. | |||. ||| |  ||| |.|     ||
vrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkpedfevrr

subfamily_PPP7C_pd Subfamily PPP7C 38-174 3.2e-40 131.0 In-house 63-201 (383) alignment
Range on Protein: 38-174
Range on HMM: 63-201/383.0
NSPINICGDIHGQFSDLLRLFDKNGFPHRA-NYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRRY--NKPSVYVS
   . .|||.||.. ||| .. |||.|    .|.| ||.|||||. .| .|.|.|. ...|..... ||||| ...|  |||  | . .|  ..  .   
skevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhilnlryGfikeveskykvhgkkilrl

FEGVFSDMPLTALVGQRILCMHGGVSKMlQNVSQLRAIKR
.| ||. .||..|. ..|| .|||.|..  ... |  |.|
ledvfawlplatlidekilivhGGisdk.tdlelldkier

Metallophos Calcineurin-like phosphoesterase 40-235 8.3e-43 140.0 Pfam-A 2-199 (200) alignment
Range on Protein: 40-235
Range on HMM: 2-199/200.0
PINICGDIHGQFSDL----LRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLL--FAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQR---------
.| ..||.||.. ||    |.|..... .   ..|||||.||||.. .||. ||  ...|. .|...|.||||||.. .|. |||..|. .         
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange

------------------------RYNKPSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVSQLraikrpfdnpepntlaidilwsdptnfqkgw
                         ....|..  .. .|  .|| |||...||..||..|. .... .                                
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................

npnsrgVSYVFGSDALRKLLDRLQIDLVVRAHQVV
       |. ||.|||.||| . ..|||.|.|. .
......gselfgpdalekllekygvdlvlrGHtHk

PPP_2 41-234 1.5e-69 226.7 In-house 1-197 (198) alignment
Range on Protein: 41-234
Range on HMM: 1-197/198.0
INICGDIHGQFSDLLRLFDKNGFPHRANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRRYNKPSVYVSFEGVFS
...|||.|||..|||.||.. ..... .||||||||||||. ||..|||.|.|. .|.....||||||.. .||.|||..|....... .||  .. ||.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe

DMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLaIDIL----WSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDRLQIDLVVRAHQV
 .||.||. ...|..|||.|. .....| . ..|. . || ..| .| |    .|||.. ........||....||.|. ..||.. ...|..|||.|
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegkl.ldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev

PPP_4 41-234 3.5e-67 219.3 In-house 1-196 (197) alignment
Range on Protein: 41-234
Range on HMM: 1-196/197.0
INICGDIHGQFSDL-LRLFDKNGFPH-RANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRRyNKPSVYVSFEGV
. ..||||||. || |.|... |.|. . .|.||||||||||. ||..|||.|.|. .|.....||||||.. .|..|||..|.... .. ...  .. |
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek.hgkeilkklqdv

FSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLAIDI-LWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDRLQIDLVVRAHQV
|. .||.||. ...|..|||.|. |........|.|... |  .... |. |||||.. |.|.... ||....||.|. .|.|.. ...|..|.|..
fdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel

PPP_5_Dcr2 41-235 1.4e-65 214.0 In-house 1-199 (199) alignment
Range on Protein: 41-235
Range on HMM: 1-199/199.0
INICGDIHGQFSDL-LRLFdKNG-FPH-RANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRRYNKPSVYVSFEG
. .|||.|||. || |.|| |.| .|  . .|.||||||||||. ||..|||.|.|. .|.....||||||.. .|.||||..|....|.. ..|  .. 
vtvcGDlHGqlddlllilf.keggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsd

VFSDMPLTALVGQRILCMHGGVSKMLQNVSQLRAIKRPFDNPEPNTLAIDI-LWSDPTNFQKG-WNPNSRGVSYVFGSDALRKLLDRLQIDLVVRAHQVV
||. .||.||. ...|..|||.|. ......|..|.|... || .    |. |||||.. |.| . .. ||....|| |. .|.|.. ...|..|.|...
vfdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshelk





Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 43-232 1.7e-06 20.2 Pfam-A 5-117 (156) alignment
Range on Protein: 43-232
Range on HMM: 5-117/156.0
ICGDIHGQFSDLLRLFDKNgfPHRANYLFLGDYVDRgkhcLETILLLFAYkvifPnhFFMLRGNHEcslinkiygfY----DECQRRYnkpsvyvsfegv
| .|.||....| .. ..      . .|..||.|..     |.. || ..    |  . ..||||.          .    .| ....            
iiSDlHgnldaleavledi..kevdlilhaGDlvep....eevvelledi....p..vlavrGnhD..........eaelpkelavel............

FSDMPLTALVGQRILCMHGGVSKmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsYVFGSDALRKLLDRLQIDLVVRAH
...   . . |.|.| .||   .                                                 .. ..|..||.  . |||. .|
llaaaaleiegdrvllvhgtpls...............................................vqsseeelaellkeagadlvflGH

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 67-283 5.3e-91 298.1 In-house 101-315 (317) alignment
Range on Protein: 67-283
Range on HMM: 101-315/317.0
ANYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRRYNKpSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNV
 .||||||||||| . .| ..||||.|. .|.. |.||||||   .|. |||| |...||.. ..| .|. .|  .||.|.|...|||||||.|. | ..
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysa.alyeafqlafnvlplcavvnkkilcmhGGiseelldl

SQLRAIKRPFDNPEPNTLAiDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAV
.|| ..|||.| |.   || |. |.|| .  ||... .|| . |||..|....|..|..||||||||||.|||||||.|.||||||||.||||.||.|||
kqldklkrpldipdvGvla.dltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaav

MYVNKNLVCSFVVLRPR
. |.|.|..|. |||| 
lsvdkklkisinvlrpe

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 68-284 2.6e-72 236.8 In-house 121-335 (339) alignment
Range on Protein: 68-284
Range on HMM: 121-335/339.0
NYLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRRYNKpSVYVSFEGVFSDMPLTALVGQRILCMHGGVSKMLQNVS
 |||||||||||   .| ..|| | |. .|.. ..||||||   .|  |||| | . ||.   .|  |. .|  .|. |.. . |.|||||.|. |  . 
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyryda.qlyecfqnmfnvfpfcavinntimcmhggisehltsfn

QLRAIKRPFDNPEPNTLaIDILWSDPTNFQKGWNPNSRGVSYVFGSDALRKLLDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVM
|.  .|||.. |.   |  |. |.||   .||..| .|| |.|||  ||| .| .|....|.| ||||.||||||  |||||||||| |||| ||.|||.
qfsvfkrpleipdvgvl.tdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavf

YVNKNLVCSFVVLRPRK
 ..|.|  |  |.||  
sidkklkisinvfrpes

subfamily_PPP7C_pd Subfamily PPP7C 186-284 1e-20 66.8 In-house 238-336 (383) alignment
Range on Protein: 186-284
Range on HMM: 238-336/383.0
IDILWSDPTNfQKGWNPN-SRGVSYVFGSDALRKLLDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFVVLRPRK
.||||||| . ..| .||  ||    ||.|  .|||.. ...|..|.|.  ..||||  .....|||||  |  .  |  | . ..|.|   .|     |
ldilwsdpka.keGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltprivqyqask