Gene ZK484.6 in Caenorhabditis elegans

Synonym: CELE_ZK484.6, ZK484.6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily CeleHP1-sf1
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP236_AA protein Get Run
CeleP236_AA_0-125 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0051064 Phosphoglycerate mutase-like 1-96 1.4e-25 83.1 In-house 2-95 (241) alignment 
Range on Protein: 1-96
Range on HMM: 2-95/241.0
MSRTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEPLYLCK
| ....|||||....|.....       | |..|| .|..||...|...|.  ....|...||..|.|.||. | . . ..  .. |.|.|.|  . . 
mmkrlyLvRHGesewnaegrlqg.....wtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaealglpllpvvvdprlrEidfgal
0043909 Phosphoglycerate mutase-like 1-91 5.5e-25 80.7 In-house 1-89 (249) alignment 
Range on Protein: 1-91
Range on HMM: 1-89/249.0
MSRTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFA--NMNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEP
|.....|||||. ..|.....       | |..|| .|..||...|....  .....|...||..|.|.||. | . ...   .. |.|.|.| 
mmkrlyLvRHGetewnaegrfqg.....wlDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileelgldklpvevdprLrEr
0036777 Phosphoglycerate mutase-like 1-101 1.2e-24 79.8 In-house 1-122 (247) alignment 
Range on Protein: 1-101
Range on HMM: 1-122/247.0
MSRTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEP------
|.....|||||. ..|.....       | |..|| .|..||...|.....  ....|...||..|.|.||. | . ...   .. |.|.|.|       
mmkrlyLvRHGetewnaegrfqg.....wlDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGale

-----------------LYLCKNPPTI
                 .. .. ....
gltkaeiaekypeelvawwrdpydyrp
0037864 Phosphoglycerate mutase-like 1-92 1.5e-22 72.5 In-house 1-95 (211) alignment 
Range on Protein: 1-92
Range on HMM: 1-95/211.0
MS-----RTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEPL
||     ....|||||....|.....       | |..|| .|..||...|...|.  ....|...||..|.|.||. | . .     .. |.|.|.|  
MslnllmtrlyLvRHGetewnaegrlqg.....wldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiilealglpllpvevdprlrErd
0049178 Phosphoglycerate mutase-like 1-91 6.9e-22 70.7 In-house 2-90 (243) alignment 
Range on Protein: 1-91
Range on HMM: 2-90/243.0
MSRTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFA--NMNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEP
| ....|||||. . |.....       | |..|| .|..||...|...|  .....|...|| .|.|.||. | . .  .  .. |.|.|.| 
mmtrlyLvRHGetewnaegrlqg.....wtDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiilealglpllpvvvdprLrEr
subfamily_PFKFB_pd Subfamily PFKFB 2-78 2.2e-10 32.3 In-house 6-77 (198) alignment 
Range on Protein: 2-78
Range on HMM: 6-77/198.0
SRTIWLVRHGQRVDNVDKKWKANNDakwddpeLTLRGKQQAHEVGKHFANMNIEAIVV--SPFTRCIETAAQIVAMMEN
 |.|.|||||.  .|. ..  ....       || ||...|....|.... |.. . |  | . | |.||  . .  |.
preiylvRhGeseknkkgriggdse.......LterGveyakklakfikeenlkelrvwtselkrtiqTaellglpkeq
subfamily_STS_pd Subfamily STS 3-126 2e-40 130.7 In-house 1-150 (245) alignment 
Range on Protein: 3-126
Range on HMM: 1-150/245.0
RTIWLVRHGQRVDNVDKKW------------------------KANNDAKWDDPeLTLRGKQQAHEVGKHF--ANMNIEAIVVSPFTRCIETAAQIVAMM
|||..||||.|||.| .||                        ....| |.|.| || ||..||...|...  |...||.|..||..|||.|||.|. ..
rtiyivRhgeRvdevfgkWlksfdegkyerkdlnlpkelprrpdglkdyksDpP.lterGviqAkllgraLleagikiehifcSPslrciqTaaailkgl

ENKAKICVEPGLMEPLYLCKNP-PTIPSMDKIKEYSTQVDESYKPVFEKLP
..|.||.|||||.|.|.|...| |...|....|.. .|.||.||||... .
gkkikikvepgllewlkldrkpipellspeelkkffpqidedYkpvlslse
0036887 Phosphoglycerate mutase-like 3-96 8.4e-24 76.7 In-house 2-88 (202) alignment 
Range on Protein: 3-96
Range on HMM: 2-88/202.0
RTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFANMNIEAIVVSPFTRCIETAAQIVAMMEnkAKICVEPGLMEPLYLCK
....|||||....||....       . |..|| .|..||...|...|.... |...||..|.|.||. |.. ..   ...|.|.|.|  . . 
trlyLvRHGetewnvegrlqg.....dldvpLtelGreqaralgerlaglpfdavysSpllRaiqTaeiiaealg..lpvivdprlrEidfgal
0053607 Phosphoglycerate mutase-like 3-92 2e-20 65.6 In-house 2-80 (191) alignment 
Range on Protein: 3-92
Range on HMM: 2-80/191.0
RTIWLVRHGQRVDNVDKKWKAnndakwdDPELTLRGKQQAHEVGKHFA--NMNIEAIVVSPFTRCIETAAQIvammenKAKICVEPGLMEPL
....|||||. . |.....         |..|| .|..||. .....|  .... |...||..|...||. |      . .. |.|.|.|  
trlyLvRHGetewnaegrlqg.......dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii......glpvevdprlrEid
subfamily_PGAM5_pd Subfamily PGAM5 3-92 3.8e-10 31.2 In-house 2-83 (189) alignment 
Range on Protein: 3-92
Range on HMM: 2-83/189.0
RTIWLVRHGQRVDnvdkkwkannDAKWDDPELTLRGKQQAHEVGKHFANMNI--EAIVVSPFTRCIETAAQIVAMMENKAKICVEPGLMEPL
| . |||||| |.          | . |.  || .|..||...|| ....|.  . .| |  .| .|||  |.  .... |  .   | |  
rhlilvrhgqyvl..........dddsdkkiltelGrrqaeltGkrlkelnlkftklvastmvravetadiiskqlpdvpkktktellreGa
0048955 Phosphoglycerate mutase-like 4-95 8.4e-25 80.5 In-house 2-91 (240) alignment 
Range on Protein: 4-95
Range on HMM: 2-91/240.0
TIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEPLYLC
...|||||....|.....       | |..|| .|..||...|...|.  ........||..|.|.||. | . . ..  ...|.|.|.|  . .
rlyLvRHGesewnaegrlqg.....wtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaealglpllpvvvdprlrErdfga
0035570 Phosphoglycerate mutase-like 4-93 4.7e-23 74.3 In-house 1-79 (219) alignment 
Range on Protein: 4-93
Range on HMM: 1-79/219.0
TIWLVRHGQRVDNVDKKWKAnndakwdDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIvammenKAKICVEPGLMEPLY
...|||||....|.....         |..|| ||..||...|...|.  ... |...||..|.|.||. |      . .....|.|.|  .
rlyLvRHGetewnlegrlqg.......dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii......glpveidprLrEidf
His_Phos_1 Histidine phosphatase superfamily (branch 1) 4-106 4.8e-23 74.8 Pfam-A 1-101 (158) alignment 
Range on Protein: 4-106
Range on HMM: 1-101/158.0
TIWLVRHGQRVDNVDKKWKANNDakwddPELTLRGKQQAHEVGKHFA--NMNIEAIVVSPFTRCIETAAQiVAMmENKAKICVEPGLMEPLY-LC--KNP
...|||||... | ..... ..|     ..|| .|..||.|.||...  . .|.|...||..|.|.||.. ..  | . .|. ||.| |  .  .  .. 
rlylvRHGesewnkegrlqgwsd.....vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaei.lle.eldipiikeprLrerdfgeweglpk

PTIPSMDK
. .... .
eevkeefp
His_Phos_1 Histidine phosphatase superfamily (branch 1) 4-106 4.8e-23 74.8 In-house 1-101 (158) alignment 
Range on Protein: 4-106
Range on HMM: 1-101/158.0
TIWLVRHGQRVDNVDKKWKANNDakwddPELTLRGKQQAHEVGKHFA--NMNIEAIVVSPFTRCIETAAQiVAMmENKAKICVEPGLMEPLY-LC--KNP
...|||||... | ..... ..|     ..|| .|..||.|.||...  . .|.|...||..|.|.||.. ..  | . .|. ||.| |  .  .  .. 
rlylvRHGesewnkegrlqgwsd.....vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaei.lle.eldipiikeprLrerdfgeweglpk

PTIPSMDK
. .... .
eevkeefp
0039931 Phosphoglycerate mutase-like 4-91 1.1e-22 73.0 In-house 1-77 (219) alignment 
Range on Protein: 4-91
Range on HMM: 1-77/219.0
TIWLVRHGQRVDNVDKKWKAnndakwdDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIvammenKAKICVEPGLMEP
...|||||. ..||....         |..|| ||..||...|.....  ... |...||..|.|.||. |      . .....|.|.| 
rlyLvRHGetewnvegrlqg.......dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii......glpveidprLrEi
0053031 Phosphoglycerate mutase-like 4-125 1.5e-16 53.8 In-house 6-159 (342) alignment 
Range on Protein: 4-125
Range on HMM: 6-159/342.0
TIWLVRHGQR--VDNVDKKWKANNDAKWDDPELTLRGKQQAHEVGKHFANM---------NIE--AIVVSPFTRCIETAAQIVAMME--NK---------
.|.||||| |  ... .. .. .   .....||| .|..||.|.|... ..         | .   . .|.. |....|. ..| .   ..         
vivlvRHGaRtPlskgpldplnewfypcgageLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtlqSAqaflaGlfppegtpilnpllg

---AKICVEPGLMEPL-----YLCKNPPTIPSMDKIKEYSTQVDESYKPVFEKL
    .| .||  ...|     . |..  .. . ..  |.  .. |.|.....||
wqpipihtepessdalllpnydpcpafdkllkealaseevkellerylellqkl
subfamily_TFC7_pd Subfamily TFC7 4-124 1.6e-16 51.7 In-house 2-126 (255) alignment 
Range on Protein: 4-124
Range on HMM: 2-126/255.0
TIWLVRHGQRVDNVDKKWKANNDA-KWDDPELTLRGKQQAHEVGKHFANMNIE--AIVVSPFTRCIETAAQIVAMMEnkAKICVEPGLMEPLYLCKNPpT
||.. ||| | . ..| ....      .|. |. || .||.|....  .....  ||. ||. ||.||.  |. ..|    . |. |..| .   . |  
tiyiarhGyrsnwlpkgpypdpltgidsdvPlserGveqakelaiylkkldlkpeaifssPlyrcletskpiaeele..iPvyvdrGvgewykpdrrP.v

IPSM---DKIK-EYSTQVDESYKPVFEK
|.     . ..  . . ... |..   .
ilePasnevlskffPsvisldyestltp
0050036 Phosphoglycerate mutase-like 4-91 1.8e-16 52.5 In-house 2-75 (171) alignment 
Range on Protein: 4-91
Range on HMM: 2-75/171.0
TIWLVRHGQRVDNVDKKWkanndAKWDDPELTLRGKQQAHEVGKHFanmNIEAIVVSPFTRCIETAAQIVammenkAKICVEPGLMEP
...|||||. . |.....       | |..|| .|..||. .|...   .. |...|| .|...||. |        .. |.|.|.| 
rlyLvRHGetewnlegrf.....qgwtdvpLtelgraqaralgell...pfdavysSpllRArqTaelil......lpvivdprLrEr
0049226 Phosphoglycerate mutase-like 4-124 2e-13 43.4 In-house 6-158 (342) alignment 
Range on Protein: 4-124
Range on HMM: 6-158/342.0
TIWLVRHGQR--VDNVDKKWKANNDAKWDDPELTLRGKQQAHEVGKHFANM-----------NIEAIVVSPFTRCIETAAQIVAMMENK-----------
...|.||| |  ... .. .. .    ....||| .|..||.|.|... ..           ..  .  |.. |....|. ..| . .            
vqvliRHGdRtPlakgpldflnewfwgcglgeLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtlqSaqaflaGlfppeltpilvplld

---AKICVEPGLMEPLYLCkNPPTIPSMDKIK------EYSTQVDESYKPVFEK
    .| .||  ...| |  .  . | .||.       |.  .. |.......|
wqpipiitepesndtllll.pydscpnfdkllkellkseevqlfleeildllkk
0046349 Phosphoglycerate mutase-like 4-92 2.4e-13 43.1 In-house 10-123 (409) alignment 
Range on Protein: 4-92
Range on HMM: 10-123/409.0
TIWLVRHGQRV--------DNVDKKWKANndAKWDDPELTLRGKQQAHEVGKHFANM---------------NIEAIVVSPFTRCIETAAQIVAMMENKA
...|.|||.|         .|.. ..  |   ......|| .|..||.|.||.. ..               ..  .. |.. |....|. ..| .    
vqvlfRHGaRtPtkklsflpnwpginwtn..gpcgagqLTplGreqayelGkrlrkrYvdlgLlpsnslynpdeiyvrssdvdRtlqSAqaflaGlfppl

KICVE----PGLMEPL
.. .     ..|..|.
ggeivpllrqdlldpp
0047369 Phosphoglycerate mutase-like 4-119 1.1e-11 37.7 In-house 47-208 (438) alignment 
Range on Protein: 4-119
Range on HMM: 47-208/438.0
TIWLVRHGQRVD---------NVDKKWKANNDAKWDD-------------PELTLRGKQQAHEVGKHFANM-------NIEAIVVSPFTRCIETAAQIVA
...|.||| |           .. .......  ....             ..|| .|..|| |.||.. ..       ..  .  |.. |....|.  .|
vqvlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcgagqLTplGreqayelGkrlrkrYglLnpedvlyvrssdvdRtlqSAqafla

MME--N-----------KAKICVEPGLMEPLYLCKNPPTIPSMDKIKEYSTQVDES----YK
 .   .            ..| ..|. ...|.   .  . | .|....   . ||     .|
Glfppegtgelapilwqpipihtipesddfllnllpsdscpafdellkeflasdeflelllk
0049059 Phosphoglycerate mutase-like 4-117 2.1e-11 36.5 In-house 46-200 (435) alignment 
Range on Protein: 4-117
Range on HMM: 46-200/435.0
TIWLVRHGQRV--------------------DNVDKKWKANNDA--KWDDPELTLRGKQQAHEVGKHFANM-------NIEAIVVSPFTRCIETAAQIVA
.. |.||| |                      ... ...  ||    ....||| .|..||.| ||.. ..       .   .  |.. |....|.  .|
vqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrYgfLynpdevyvrssdvdRtlqSaqafla

MMENKA------------KICVEPGLMEPLYLCKNPPTIPSMDKIKEYSTQVDES
 . .              .. | .  ..... . .. . | .|....   . || 
Glfppeilgsqllnplnvyqpvpietvdsdndtlpydscpafdellkellasdef
subfamily_PGAM_pd Subfamily PGAM 4-79 7.2e-10 30.6 In-house 2-74 (248) alignment 
Range on Protein: 4-79
Range on HMM: 2-74/248.0
TIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIVAMMENK
.. |.|||.   | ..|. .     | | .|. .||..|...||   .  .... .. |  .|...|.. |.  ....
klvllRhGeselnkenkfcg.....wvDakLsekGkeeAkkagkalkqanlefdivytSvlkRaqqTlevileeldqe
subfamily_Dicty-HP1-1_pd Subfamily Dicty-HP1-1 4-83 3e-09 27.0 In-house 2-82 (210) alignment 
Range on Protein: 4-83
Range on HMM: 2-82/210.0
TIWLVRHGQRVDNVDKkwKANNDAKWDDPELTLRGKQQAHEVGKHFANM--NIEAIVVSPFTRCIETAAQ-IVAMMENKAKIC
 ....|||.   |..   .  .|    |  ||  ||.|| |. .   ..  ..| .. ||.|| ..|. . .. .. .|.  |
kvyiirhgestfnkay..nekvdpylfdarlteegkkqanelsenvekllqdvelvisspltraldttkiallkllkeksikc
0048946 Phosphoglycerate mutase-like 5-92 1.5e-11 37.0 In-house 45-176 (447) alignment 
Range on Protein: 5-92
Range on HMM: 45-176/447.0
IWLVRHGQRV-------------------------------DNVDKKWKANNDAKWDDPELTLRGKQQAHEVGKHFANM--------NIEAIVVSPFTRC
. |.||| |                                .. .. .|..    .. ..|| .|..|..|.||.. ..        .   .  |.. |.
qvlfRHGaRtPtkkylkgleplldllknanvlelggdlsflndwkyqlkneplwpcglgqLTplGreqlyelGkrlrkrYlgllpnpseiyvrssdvdRt

IETAAQIVAMMENKA-----KICVEPGLMEPL
...|.  .| . ..      .. . . .... 
lqSaqaflaGlfppepplgyqpipihtvpssn
subfamily_TIGAR_pd Subfamily TIGAR 5-90 4.7e-11 34.8 In-house 3-85 (222) alignment 
Range on Protein: 5-90
Range on HMM: 3-85/222.0
IWLVRHGQRVDNVDKKWKANNdakwdDPELTLRGKQQAHEVGKHFANMNIEAIVVSPFTRCIETAAQIVAMMEN--KAKICVEPGLME
...||||.   |  |  . .      |  |. .| .||  |.|  .|..|. |. |.  |  .||  |   ..   .... ... | |
livVrhGetefnkekilqgqt.....dtpLsekGveQakrvakrLsnekinyifsSdllRAkqTaeiilkalkekkreaverdkrLrE
0048439 Phosphoglycerate mutase-like 5-84 1e-10 34.6 In-house 13-116 (391) alignment 
Range on Protein: 5-84
Range on HMM: 13-116/391.0
IWLVRHGQRVDNVDKKWK-------ANNDAKWDDPELTLRGKQQAHEVGKHFA---------------NMNIEAIVVSPFTRCIETAAQIVAMMENK--A
. |.||| |   .. . |         .  .....||| .|..|..| |...                | ..  .  |.. |....|.  .| . .    
qvlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevyvrssdvdRtlqSAqaflaGlfpplgl

KICV
.. .
tvil
subfamily_Cele-STS-like_pd Subfamily Cele-STS-like 31-121 1.5e-12 38.3 In-house 49-139 (229) alignment 
Range on Protein: 31-121
Range on HMM: 49-139/229.0
DPELTLRGKQQAHEVGKHFANMNIEAIV--VSPFTRCIETAAQIVAMME-NKAKICVEPGLMEplYLCKNPPTIPSMdKIKEYSTQVDESYKPV
|| || .|| ... .|.   .  ||  |   ||  |...||| ..  .  ..|.| |||||.|  |   ..  .|   ..|.    ||| |||.
dpPlteiGkiaskligRaLrdrgiepsvvFCSPdlrsvqtaalllkglGlkraaisvePgLle..yrkarevllppk.afkklgypvdekYkPl