Gene DDB_G0288645 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily HP1-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP085_AA protein Get Run
DdisP085_AA_11-167 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TIGAR_pd Subfamily TIGAR 12-201 2.7e-44 143.5 In-house 8-148 (222) alignment 
Range on Protein: 12-201
Range on HMM: 8-148/222.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLSrgNMPINLIISSDLDRAFETASIIRQQLIINNHTSgsgnnnnnilpsIESTQLLRERNLGKLEG
||||.|||..||||....||..||..||.....|||  |..||.|.||||.||..||.||...| ......            .|... ||||..|..||
hGetefnkekilqgqtdtpLsekGveQakrvakrLs..nekinyifsSdllRAkqTaeiilkalkekkrea............verdkrLrEreyGvyeG

VDLRQLVH--------WEEIPDAKKAIEiQKLLNQKPSLSFLPPSNHHQQQQL-SlqnqlnqlyieqqqqqqqqqqqqqqqqqqqqqqqepqhlninlQ
|.|..| .        ....|.....|| |..|.....|..|.....|....                                              .
valdelrellkaagnvpsfvpegGesie.qlelrlvaaleelcakilhleadkkk...........................................d
0043909 Phosphoglycerate mutase-like 12-119 1.6e-23 75.9 In-house 10-104 (249) alignment 
Range on Protein: 12-119
Range on HMM: 10-104/249.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIRQQLiinnhtsgsgnnnNNILPSIESTQLLRERNLGKLEG
||||..|..|..||.|..||. .|| ||  .||.|.. ..|.....||.| || .|| || ..|             ..  . .| .  ||||..| |||
HGetewnaegrfqgwlDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileel.............gldklpvevdprLrErdfGaleg

VDLRQLVH
 .. ..  
ltkaeiae
0036777 Phosphoglycerate mutase-like 12-119 3.6e-23 74.9 In-house 10-104 (247) alignment 
Range on Protein: 12-119
Range on HMM: 10-104/247.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIRQQLiinnhtsgsgnnnNNILPSIESTQLLRERNLGKLEG
||||..|..|..||.|..||. .|| ||  .||.|.. ..|.....||.| || .|| || ..|             .. |. .. .  ||||..| |||
HGetewnaegrfqgwlDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiileal.............glsllpvvvdprLrErdyGaleg

VDLRQLVH
 .. ..  
ltkaeiae
0049178 Phosphoglycerate mutase-like 12-119 7.8e-23 73.8 In-house 11-105 (243) alignment 
Range on Protein: 12-119
Range on HMM: 11-105/243.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIRQQLiinnhtsgsgnnnN--NilPSIESTQLLRERNLGKL
||||..|. |.|||....||. .|| ||  .||.|.. ........||.| || .|| || ..|             .  .  . .. .  ||||..| |
HGetewnaegrlqgwtDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiileal.............glpl..lpvvvdprLrErdfGal

EGVDLRQLVH
||  . ..  
egltkaeiaa
0037864 Phosphoglycerate mutase-like 12-119 1.7e-22 72.3 In-house 15-109 (211) alignment 
Range on Protein: 12-119
Range on HMM: 15-109/211.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIRQQLiinnhtsgsgnnnNNILPSIESTQLLRERNLGKLEG
||||..|..|.|||.|..||. .||.||  .||.| . ..|.....||.| || .|| || ..|             .  |...| .  ||||..| |||
HGetewnaegrlqgwldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiileal.............glpllpvevdprlrErdfgaleg

VDLRQLVH
  | ..  
ltleeiae
0048955 Phosphoglycerate mutase-like 12-127 1.3e-21 70.1 In-house 8-108 (240) alignment 
Range on Protein: 12-127
Range on HMM: 8-108/240.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIRQQLiinnhtsgsgnnnNNILPSIESTQLLRERNLGKLEG
|||...|..|.|||. ..||. .|| ||  .||||.. .... |..||.| || .|| || ..|             .. |. .. .  ||||..| |||
HGesewnaegrlqgwtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaeal.............glpllpvvvdprlrErdfgaleg

VDLRQLVhwEEIPDAK
  | ..   |. |.. 
ltldeia..ekfpeel
0051064 Phosphoglycerate mutase-like 12-151 3.8e-21 68.6 In-house 11-135 (241) alignment 
Range on Protein: 12-151
Range on HMM: 11-135/241.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIRQQLiiN--NhtsgsgnnnnnilPSIESTQLLRERNLGKL
|||...|..|.|||. ..||. .|| ||  .||||.. ........||.| || .|| || ..|  .  .             . .. .  |||...| |
HGesewnaegrlqgwtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaeal..glpl.............lpvvvdprlrEidfgal

EGVDLRQLvhWEEIPDAKKAIEIQKLLNQKPSLSFLPPSNHH
||  | ..  .|. |..  |.   .|  . | |..| .  ..
egltleei..aekfpeelvawlrdpldvrppllelldlllll
0036887 Phosphoglycerate mutase-like 12-119 9.6e-21 66.8 In-house 9-98 (202) alignment 
Range on Protein: 12-119
Range on HMM: 9-98/202.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLSrgNMPINLIISSDLDRAFETASIIRQQLiinnhtsgsgnnnNnilPSIESTQLLRERNLGKLEG
||||..|..|.|||.|..||. .|| ||  .||||.  ..|. ...||.| || .|| || ..|             .    ... .  |||...| |||
HGetewnvegrlqgdldvpLtelGreqaralgerla..glpfdavysSpllRaiqTaeiiaeal.............g...lpvivdprlrEidfgaleg

VDLRQLVH
. | .. .
ltleeiae
0050036 Phosphoglycerate mutase-like 12-119 1.3e-20 65.9 In-house 8-90 (171) alignment 
Range on Protein: 12-119
Range on HMM: 8-90/171.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLsrgnmPINLIISSDLDRAFETASIIRqqliinnhtsgsgnnnnnilPSIESTQLLRERNLGKLEG
||||..|..|..||....||. .|| ||  .||.|     |. ...||.| || .|| .|                     .... .  ||||..| .||
HGetewnlegrfqgwtdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil....................lpvivdprLrErdfGaweg

VDLRQLVH
 .| .. .
ltldeiaa
0039931 Phosphoglycerate mutase-like 12-119 3.7e-20 64.8 In-house 7-92 (219) alignment 
Range on Protein: 12-119
Range on HMM: 7-92/219.0
HGETDFNKNGILQGhlNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIrqqliinnhtsgsgnnnnNiLPsIESTQLLRERNLGKLEG
||||..|..|.|||  ..||. .||.||  .||||.. ..|. ...||.| || .|| ||                  . || .| .  |||...| |||
HGetewnvegrlqg..dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii..................g.lp.veidprLrEidfgdleg

VDLRQLVH
 .| .. .
ltleeiae
0035570 Phosphoglycerate mutase-like 12-119 4.1e-20 64.7 In-house 7-92 (219) alignment 
Range on Protein: 12-119
Range on HMM: 7-92/219.0
HGETDFNKNGILQGhlNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIrqqliinnhtsgsgnnnnNiLPsIESTQLLRERNLGKLEG
||||..|..|.|||  ..||. .|| ||  .||.|.. ..|. ...||.| || .|| ||                  . || .| .  |||...| |||
HGetewnlegrlqg..dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii..................g.lp.veidprLrEidfgdleg

VDLRQLVH
 .| ..  
ltldeiae
0053607 Phosphoglycerate mutase-like 12-119 1.6e-19 62.7 In-house 9-94 (191) alignment 
Range on Protein: 12-119
Range on HMM: 9-94/191.0
HGETDFNKNGILQGhlNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIrqqliinnhtsgsgnnnnniL-PsIESTQLLRERNLGKLE
||||..|..|.|||  ..||. .|| ||  ..|.| . .... ...||.| || .|| ||                      | .| .  |||...| .|
HGetewnaegrlqg..dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii....................glp.vevdprlrEidfgdwe

GVDLRQLVH
|  | .|  
gltleelae
His_Phos_1 Histidine phosphatase superfamily (branch 1) 12-167 1.8e-18 60.0 Pfam-A 7-138 (158) alignment 
Range on Protein: 12-167
Range on HMM: 7-138/158.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIRQQLIinnhtsgsgnnnnnilPSIESTQLLRERNLGKLEG
|||...||.|.|||. . ||..||| || ..|..|.| . ||. ...|.| || .|| |....|                   |. .. ||||..|..||
HGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeld................ipiikeprLrerdfgeweg

VDLRQLvhWEEIPdakkaieIQKLLNQKPSLSFLPP-SNHHQQQQLSLQNQLNQLYI
 . ...  .|| |        ..   .. . .| ||     .. .  ... |..|. 
lpkeev..keefp.......eeyekwkrdkkefrppegesladvyeRvapfleelie
His_Phos_1 Histidine phosphatase superfamily (branch 1) 12-167 1.8e-18 60.0 In-house 7-138 (158) alignment 
Range on Protein: 12-167
Range on HMM: 7-138/158.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIRQQLIinnhtsgsgnnnnnilPSIESTQLLRERNLGKLEG
|||...||.|.|||. . ||..||| || ..|..|.| . ||. ...|.| || .|| |....|                   |. .. ||||..|..||
HGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeld................ipiikeprLrerdfgeweg

VDLRQLvhWEEIPdakkaieIQKLLNQKPSLSFLPP-SNHHQQQQLSLQNQLNQLYI
 . ...  .|| |        ..   .. . .| ||     .. .  ... |..|. 
lpkeev..keefp.......eeyekwkrdkkefrppegesladvyeRvapfleelie
subfamily_PGAM_pd Subfamily PGAM 12-117 9.1e-16 49.9 In-house 8-100 (248) alignment 
Range on Protein: 12-117
Range on HMM: 8-100/248.0
HGETDFNKNGILQGHLNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIRQQLiinnhtsgsgnnNNNILPsIESTQLLRERNLGKLEG
|||...||. ...|.    |..||...|  ||. | . |. .... .|.| || .|...| ..|            ... .| .|.|  |.||. |.|.|
hGeselnkenkfcgwvDakLsekGkeeAkkagkalkqanlefdivytSvlkRaqqTlevileel............dqekiP.vektwrLnErhyGaltg

VDLRQL
.. .. 
lnkaev
subfamily_STS_pd Subfamily STS 26-75 2.1e-06 19.3 In-house 50-99 (245) alignment 
Range on Protein: 26-75
Range on HMM: 50-99/245.0
HLNIPLNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIRQQL
. . ||.. | .||   |..|.  .. |. |..|   |  .||. | ..|
ksDpPlterGviqAkllgraLleagikiehifcSPslrciqTaaailkgl
subfamily_PGAM5_pd Subfamily PGAM5 31-78 3.2e-09 28.2 In-house 23-70 (189) alignment 
Range on Protein: 31-78
Range on HMM: 23-70/189.0
LNNKGRHQAISAGERLSRGNMPINLIISSDLDRAFETASIIRQQLIIN
| ..||.||   |.||   |.. . ...| . || |||.|| .||  .
ltelGrrqaeltGkrlkelnlkftklvastmvravetadiiskqlpdv
Med15 ARC105 or Med15 subunit of Mediator complex non-fungal 137-290 1.1e-07 16.7 Pfam-A 328-472 (799) alignment 
Range on Protein: 137-290
Range on HMM: 328-472/799.0
NQKPSLSFlPPSNHHQQQQLSLQNQLNQLYIEQQQQQQQQQQQQQQQQQQQQQQQEPQHLNINLQEIKSITMKTTtssqtpslsSTASYTSTAVQS----
.|.|.|   . ... ||. || ..| ..|   .. .||||.|||||||..|||....|. ... .. . ..   .          .   . .. ||    
sQqpglva.qggqavqqsvlsaeqqqlkllkavrvrqqqqaqqqqqqqegqqqaaqqqqvalqvgqgaqvvalea.........gaqvaarlpqqsaqsa

------TASSIPSSPRSSSQTTSLSSSSSSisnfstssnSSFSSFSSLSSSLEVPIPSNSFPTP
          .   . . .. . .|| |            .     |. .|  . .||.. |. 
aaqqqgnqgglganqvqqkspemmsspspv.........rqvqtnqsmrqspqpsvpspqqPgs