Gene DDB_G0282759 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily PFKFB
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP087_AA protein Get Run
DdisP087_AA_381-583 phosphatase_domain Get Run
Domains
Summary
200400MHKSISNNIFTTQITVDNNHNDHDESNYSIPKSSPSSSPPGSNIAGSSSPSSNRYGNNFNINNNNDNNNYNVNSPTPSTTTTSSSSIPNSREIFFRVKDRVKKAYFKGISVEDLKFLFLQKFPEFPKDVDIQFLIIDKGTNKEQQVIDVNDIKEHQELLIRHEYNEDTKKRSQGYTGLDKEKIVLVMVGLPARGKTYVARKICRMLNWMLVPAKVFNVGEYRRLRIGAGQPHDFFDPHNPEGIKARLHMAVAALDDMISWLHNGGRVGIYDATNSTNERRQLVEKRCTREKMTVVYVESICNDASVIEHNIKETKLLSPDYQGVDPSKAVQDFRDRINHYLKVYETVEGEKTRYIKLFDVGKKIEVNNITGYIPSRVVFFLMNLHLHPRPIWLTRQGESEFNAQNRIGGDSDLTERGDNYAHQLAVWISEWCSKVRADGYDGEVVVWTSSLKRAIRTAQYISQPKVVMRALDEIDAGVCDGMTYEEIQEKMPDERAARDSDKLQYRYPRGESYEDVIQRLEPLLLELERTKSPVLIVSHQATLRCLYSYLKGRVKEECPFINIPLHTLIQLSPKAYGCEETTFKLANHP1Curated phosphatase domainD6PF2KHis_Phos_1Pfam Domainsubfamily_PFKFB_pd(1)0039931(2)0035570(3)0053607(4)0037864(5)Subfamily
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
6PF2K 6-phosphofructo-2-kinase 176-388 2.3e-80 259.2 Pfam-A 7-223 (223) alignment
AAA_33 AAA domain 184-336 1.4e-09 28.5 Pfam-A 1-139 (143) alignment
AAA_17 AAA domain 186-273 6e-06 17.7 Pfam-A 3-78 (121) alignment
0037864 Phosphoglycerate mutase-like 382-578 3.5e-45 146.3 In-house 1-202 (211) alignment
subfamily_PFKFB_pd Subfamily PFKFB 383-585 4.5e-86 279.4 In-house 1-195 (198) alignment
0051064 Phosphoglycerate mutase-like 388-577 4e-43 140.4 In-house 3-222 (241) alignment
0053607 Phosphoglycerate mutase-like 389-578 2.4e-46 149.9 In-house 2-182 (191) alignment
0036777 Phosphoglycerate mutase-like 389-577 3.5e-45 146.8 In-house 3-221 (247) alignment
0043909 Phosphoglycerate mutase-like 389-581 6.6e-45 145.8 In-house 3-229 (249) alignment
0049178 Phosphoglycerate mutase-like 389-580 4.6e-44 143.2 In-house 4-223 (243) alignment
0036887 Phosphoglycerate mutase-like 389-578 4e-43 139.6 In-house 2-190 (202) alignment
0039931 Phosphoglycerate mutase-like 391-583 1.5e-50 163.9 In-house 2-185 (219) alignment
0035570 Phosphoglycerate mutase-like 391-577 6.7e-50 161.8 In-house 2-179 (219) alignment
0048955 Phosphoglycerate mutase-like 391-575 3.2e-42 137.3 In-house 3-217 (240) alignment
0050036 Phosphoglycerate mutase-like 391-571 3.3e-38 122.9 In-house 3-165 (171) alignment
His_Phos_1 Histidine phosphatase superfamily (branch 1) 391-546 1.5e-33 109.0 Pfam-A 2-158 (158) alignment
His_Phos_1 Histidine phosphatase superfamily (branch 1) 391-546 1.5e-33 109.0 In-house 2-158 (158) alignment
subfamily_TIGAR_pd Subfamily TIGAR 391-527 3.2e-10 32.0 In-house 3-134 (222) alignment
subfamily_PGAM_pd Subfamily PGAM 392-461 5.3e-08 24.4 In-house 4-67 (248) alignment
subfamily_PGAM_pd Subfamily PGAM 495-564 8.9e-08 23.7 In-house 138-208 (248) alignment