Gene DDB_G0292214 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PPM-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP098_AA protein Get Run
DdisP098_AA_438-651 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Mitofilin Mitochondrial inner membrane protein 272-393 1.2e-09 23.7 Pfam-A 59-181 (582) alignment 
Range on Protein: 272-393
Range on HMM: 59-181/582.0
SNNNSNSINSQNCENSQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTAATTTT-INNTNTNTNTTPIVNNNNIENKEENDKNVDSNSNNNIDNNNNNSDDN
|...... .| . | ........................ ....|..|....  ..   ...  . . .. .. .|.  ..  . ... .   .  .|. 
skpqisvvssvtkeskepkeekkkeksekksslseevaeveakatseaaeakqpksiqeleealeelleellketekataqakeakeeakkavdeatdkl

NNNIDNNIINDEKNNENENENEN
....... ...||..|. .....
keaseseekarekaeeeaakelk
Macoilin Transmembrane protein 273-388 2.8e-06 14.9 Pfam-A 239-351 (697) alignment 
Range on Protein: 273-388
Range on HMM: 239-351/697.0
NNNSNSINSQNCENsqqQQQQQQQQQQQQQQQQQQQQQQQQQTTTAATTTTINNTNTNTNTTPIVNNNNIENKEENDKNVDSNSNNNIDNNNNNSDDNNN
......| ...  .   .... ................ ||.   |.......  ....... . .|.  ..|....    |... .. ...| |  ...
ahslkkisasalse...rkekgkdkaknssdkkkekkelqqknhhasksksvqsyssklqeievkenvsnkskksseslagsaeelalkkdsnsssaeek

NIDNNIINDEKNNENE
... .  . .|.....
sakskssksaktskrs
subfamily_tipA_pd Subfamily tipA 435-716 2e-120 391.1 In-house 3-295 (296) alignment 
Range on Protein: 435-716
Range on HMM: 3-295/296.0
GRRIGDPICDRFKVVVYKEKLLVTLADGCNWGRLPYEAATNATNGFISFLMENHLEVNTVRKAGSFLLAAMTAAHKSIIAGKSEVFESGTTTLIGGILAK
 .| ||||.|||.|.|||..|.|.||||||||. |.||||||...|..||.|.. |.|||..||.|||.|..||||.|..|||...|.|||||.||.|..
tkregdpiadrftvqvyknrlivaladGcnWGkrPaeaatnasaafvdflseksseintvkdaGkfllsafeaahkkiveGksdiweaGtttllGGvlle

I-----KPESENIKRMSNIHNHAVGGI---------------EDHQSSSSWVFVGVTLGDCKAFHYSKKDHTFSDITKGNRQNVSDARDPGGRLGPYIRQ
.     ||||...||.|.......|..               ....|||.|.||....||||||..|||.....|||||||.||.||.|||||||||..|
leqseskpesssqkrksevnkeviganfanltgsgngnnagsdinkssskWgfvcasvGdckafllskkskevtditkgnrsnvddakdpGGrlGPyveq

GEPDLRNLQVFYKLCDPEDLILLLSDGVHDNLDPQQLGIKPNELGIDEESWDKAAISfpiDSENAKNEYRKRWLNQhfcsdqNTLNQLEPTFISNTLLKH
|.||||||..|..||..||.|||.||||||||||..||  |..| .. | |    ..    . .||..| . .|..         ..... .||. |..|
GkPdlrnlklffllceeediillvsdGvhdnldPktlgktprdlqlnyekwsdvefd...kaleaktkytaellkk......leadsidakeiseklveh

CL
|.
cv
subfamily_CG9801_pd Subfamily CG9801 438-689 3.4e-110 357.4 In-house 2-251 (252) alignment 
Range on Protein: 438-689
Range on HMM: 2-251/252.0
IGDPICDRFKVVVYKEKLLVTLADGCNWGRLPYEAATNATNGFISFLMEN-HLEVNTVRKAGSFLLAAMTAAHKSIIAGKSEVFESGTTTLIGGILAKIK
 ||||.|.|.|||.|..|...||||||||. |.|||..|...||..|... . |..||...|..||||...|||||..||||..|.|||||.||.|....
eGdPiaDkftvvvrknrlilalaDGcnWGerpaeaarsasaafidylskalskeittvqevgksllaaleeahksivegkselweaGtttLlggvllele

PESENIKRMSNIHNHAVGGIEDHQSSSSWVFVGVTLGDCKAFHYSKKDHTFSDITKGNRQNVSDARDPGGRLGPYIRQGEPDLRNLQVFYKLCDPEDLIL
 |.|.....|......||......|||.|.||....||||||.||.|.....|||||||.|.|||||.|||||||..||.||||||..|..|.. ||.||
keaekpesssqlgksevglsasnassskwgfvcasvGDckaflysakkkevtditkgnrsnlsDarDagGrLGPyveqgkPdLrnLklfftlveeeDiil

LLSDGVHDNLDPQQLGIKPNELGIDEESWDKAAISfpiDSENAKNEYRKRWLN
|.|||||||||||.||  |..| .. |.|.    .   .  .||... |  |.
lvsDGvhDnlDPqtlgktprdlnlnaekwsdleqd...kaleaktkftkelle
subfamily_CG9081_pd Subfamily CG9081 439-649 4.2e-35 111.7 In-house 2-191 (195) alignment 
Range on Protein: 439-649
Range on HMM: 2-191/195.0
GDPICDRFKVVVYKEKLLVTLADGCNWGRLPYEAATNATNGFISFLMENHLEVN---TVRKAGSFLLAAMTAAHKSIIAGksevfESGTTTLIGGILAKI
|.|. | | ||. ... ...|||| |||. .  ||  | .| ...| ..  ...   . |.  ..|| ..  |.|||..      .. .|||  ......
gePvadvfavvarennaimaladGvnWGkkarlaarsavagavaylndklfklsakpnsrdlfklllesleeaqksilen.....sgtlttlsiavvcel

KPESENikrmsnihnhavggiedhqsSSSWVFVGVTLGDCKAFHYSKKDHTFSDITKGNRQNV--SDARDPGGRLGPYIRQgEPDLRNLQVFYKLCDPED
|.. .                     || |... |..||  .| ||.. ..  ..| .  ..    |.|..|| ||| | . .||| || . |    . |
kankki....................ssqWglfvvsvGdspvfvyspdnksvrevtvashskdgirdvrlsGGalGpaiGt.dpdlenlslsylpvaeGd

LILLLSDGVHDNLDPQ
...| |||| ||.||.
ivfltsdGvsdnfdPv
subfamily_Sponge-PPM-1_pd Subfamily Sponge-PPM-1 439-650 8e-34 106.9 In-house 2-193 (199) alignment 
Range on Protein: 439-650
Range on HMM: 2-193/199.0
GDPICDRFKVVVYKEKLLVTLADGCNWGRLPYEAATNATNGFISFLMENHLEVNTVR----KAGSFLLAAMTAAHKSIIAgksevFESGTTTLIGGILAK
|.|. | | ||. ... ....||| |||. |  ||  | .| |... .|  .... .    .   .|| ..  |||||..      |  .|||  ... .
GepvadvfavvarennaimaiadGvnwGkkprlaarcavqgaiayisdnlfklsakptnsrtltklllesldeahksile.....heGtlttlsiavvce

IKPEsenikrmsnihnhavggiedHQSSSSWVFVGVTLGDCKAFHYSKKDHTFSDITKGNRQ--NVSDARDPGGRLGPYIRQgEPDLRNLQVFYKLCDPE
.||.                    ..||| |... ...||   | || . ..  ..|    .   . .||. || ||| | . .||| || . |    . 
lkpn....................srsssrwglfvasvGdspvfvyspdtksvheatvachdkdGirtarlsGGalGpaiGt.dpdlenlslsylpvaeG

DLILLLSDGVHDNLDPQQ
|..||..||..||..|. 
divllttdGisdnfapvv
0034914 PP2C-like 439-651 1.7e-06 20.4 In-house 32-249 (295) alignment 
Range on Protein: 439-651
Range on HMM: 32-249/295.0
GDPICDRFKVVV-----YKEKLLVTLADGCNWGRLPYEAATNATNGFISFLME-NHLEVNTVRKAGSFLLAAMTAAHKSIIAGKS---EVFESGTTTLIG
 ..  |.. ||.      .. ||. ..|| .  .    |. .. . ....| .   |  ..     ..|  |. ||.. ...      |.. |||| .. 
rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallrpelagsGtTavva

GILAKikpesenikrmsnihnhavggiedhqsssswVFVGVTLGDCKAFHYskKDHTFSDITKGNRQNVSDARDPGGRLGPYIRQgepDLRN--------
 |  .                                ..   .||..|. .  .....  .|.  . .  . |    ..|....    . .|        
lirgn...............................klyvanvGDSravll..rngelvqltvdhkpvnelererilsaggavsh...grvngvlavtRa

-----------------------LQVFYKLC-DPEDLILLLSDGVHDNLDPQQL
                          ...|  .. |..|| |||..|.|.....
lGdfdlklllslllleplvsaePdvtvleltledddfllLasDGlwdvlsneei
0049733 PP2C-like 444-651 8.3e-08 25.2 In-house 20-197 (235) alignment 
Range on Protein: 444-651
Range on HMM: 20-197/235.0
DRFKVvvykEKLLVTLADGCNWGRLPYEAATNATNGFISFLMEnhlevNTVRKAGSFLLAAMTAAHKSIIAGKS---EVFESGTTTLIGGILAKIkpese
|.. |    . ||. .||| . ..    |. .. . ....|.|      .  .   .| .|..||.. ...      |.. .||| ..  .  .      
Davlv....glllfavaDGhgghaagevasellvetllellle.....lllldleealrkaflaaneallelalaspelagmgtTavvalldggk.....

nikrmsnihnhavggiedhqsssswvFVGVTLGDCKAFHYSkkDHTFSDITKGNRQNVSDARD----PGGR------------LGPYIRQgepdlrnLQV
                          .. . .||. |....  | ..  .|. .. .  . |     .||.            || .  .        .|
..........................lyvanvGDsrayllr..dgklvqltedhspvnelerqriitaggavrvpgrlaltralGdlllk.......pdv

FYKLCDPEDLILLLSDGVHDNLDPQQL
..   .|.|..|| |||..|.|.....
tvlelepgdflllasDGlwdvlsdeei