Gene DDB_G0288107 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PTC7
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP110_AA protein Get Run
DdisP110_AA_144-388 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0034914 PP2C-like 145-388 1.7e-25 82.7 In-house 5-290 (295) alignment
Range on Protein: 145-388
Range on HMM: 5-290/295.0
SNPNYEIIVQNSTKKFYFKGMINSVGKqQGICEDSHFL-------SKDFTTIGVADGVGSWRSVGIDPGEYSRFLMSFIYGQ--SLTTPYLKPYELIESA
|.|..|..  .| . ..  |.   .|.    .||...         .|.. .||.||.|...   .    . ..|....  .  .||...  . | ...|
slpllellllsslllllrvgvasdqGr.rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrka

YRES------------VNIPGSSTICILKIIGSKVYSGLVGDSSFIQIRKDQIYFRSNEQTHKPNFPYQ-----------------------LGQNSVD-
. .               . ...|.... |.|.|.| . |||| .. .|...... ......  .  ..                       ||  .   
flaadeellelallrpelagsGtTavvalirgnklyvanvGDSravllrngelvqltvdhkpvnelererilsaggavshgrvngvlavtRalGdfdlkl

-------------KPSSGvYMEHPIQENDIFVIGTDGFFDNIFDQEIVKAIKE----VNSIESFFKCLMELAKSksqdpeaqtpigqrngkiGGKNDDIT
              |    ..|  ....|......||..|.. ..|||. ...     ...|   . |..|| .                  .|. |.||
llslllleplvsaePdvt.vleltledddfllLasDGlwdvlsneeivdivrsllakgldleeaaeeLvdlAla..................rgsrDNiT

VGCFVI
| .  .
vvvvrl

0049733 PP2C-like 167-385 6.6e-30 97.3 In-house 9-230 (235) alignment
Range on Protein: 167-385
Range on HMM: 9-230/235.0
NSVGKQQGICEDSHFLskDFTTIGVADGVGSWRSVGIDPGEYSRFLMSFIYGqsltTPYLKPYELIESAYRES------------VNIPGSSTICILKII
  .|... ..||....  ... ..||||.|...  ..  . . ..|......    ...|.. |....|...                 . .|.... ..
sdigrvrkvneDavlv..glllfavaDGhgghaagevasellvetllellle....lllldleealrkaflaaneallelalaspelagmgtTavvalld

GSKVYSGLVGDSSFIQIRKDQIYFRSNEQTHKPNFPYQ--------------------LGqN-SVDkpssGVYMEHPIQENDIFVIGTDGFFDNIFDQEI
|.|.|   |||| .. .|........ ....  ....|                    || .  ..      .........|.... .||..|.. |.||
ggklyvanvGDsrayllrdgklvqltedhspvnelerqriitaggavrvpgrlaltralG.dlllk....pdvtvlelepgdflllasDGlwdvlsdeei

VKAIKEvNSIESFFKCLMELAKSksqdpeaqtpigqrngkiGGKNDDITVGC
|. ... ...|   ..|.||| .                  .|. |.||| .
vdllrs.ldleeaaerlvelala..................rggrDNiTvvv

subfamily_PPTC7_pd Subfamily PPTC7 170-388 2.7e-81 265.7 In-house 5-251 (252) alignment
Range on Protein: 170-388
Range on HMM: 5-251/252.0
GKQQGICEDSHFLS--KDFTTIGVADGVGSWRSVGIDPGEYSRFLMSFIYGQSLTTPY--LKPYELIESAYRESVNIP----GSSTICILKIIGS--KVY
||.| ..||..|.|  |.....|||||||.||||||||.|.||.||.... .| .. .  |||.||.|.||.|... .    ||||.||... .|  |..
gkrqkageDayfvsseksadvlgvADGVggWrsvGiDpsefsreLmkaceklskeskaeelkPvelleaayqelleekvpvlGssTacivvldksdkkle

SGLVGDSSFIQIRKDQIYFRSNEQTHKPNFPYQL--------GQNSVDKPSSGVYMEHPIQENDIFVIGTDGFFDNIFDQEIVKAIKEVN-----SIESF
|  .|||.|...||....|||.||.||.|.||||        |....|||.............||.|..|||.|||....||....||..     |..|.
sanlGDSgflvvRkgkvvfrskeqqhkfntPyQLsiapegregkvildkpeaadsksfavkkgDiivlatDGlfDNlledeileilkelkeseksslqsl

FKCLMELAKSKSQDPEAQTPIGQRNGKI-----GGKNDDITVGCFVI
.|.|.| |...|.|||...|..|...|      |||.||||| ..|.
akklaekarelsldpeyespfaqkakkngleasGGKpDDitvvvavv

PP2C_SIG_SM00331 183-383 6.1e-08 25.5 In-house 27-212 (217) alignment
Range on Protein: 183-383
Range on HMM: 27-212/217.0
SKDFTTIGVADGVGswrsVGIDPGEYSRFLMSFIYGQSLT--TPYLKPYELIESAYRESVNIPGSSTICILKI--IGSKVYSGLVGDSSFIQIRKDQIYF
... . . ||||.|     |.. ...|. | . .  ..    ..   . .|.. .|.|...  .  |......   ..|..   .||| .. .|...  .
negrlllvvaDgmG....kGlaAaaassqlrtalrellsegeelsqalkrlnraiyeekeekgmfaTlllalydfssgklsyanaGdsrpyllrdgklve

RSNEqthkpNFPYQLGQNSVDKpssGVYMEHPIQENDIFVIGTDGFFDNIFD--------QEIVKAI--KEVNSIES-FFKCLMELAKSKSQdpeaqtpi
.  .     . ...||  .  .       |  ... |.... ||| ...  .        .||...    |.  . . ....|.|||| . .        
ilkd.....vegaplGlepevs...vdirelelekgdllllytDGltearsekgfaeerleeiledlvdseaqelaqkiveellelakgsng........

gqrngkiggkNDDITV
          .|||||
..........eDdiTv

PP2Cc_SM00332 309-384 2e-06 20.4 In-house 208-272 (274) alignment
Range on Protein: 309-384
Range on HMM: 208-272/274.0
HPIQENDIFVIGTDGFFDNIFDQEIVKAIKEVN------SIESFFKCLMELAKSKsqdpeaqtpigqrngkiGGKNDDITVG
   .|...... .|| .|.. .||.|. ...        . . . . |.|.| ..                 ||..|.||| 
tltsedeflilaSDGlwdvlsnqevvdivrkllakgktndpqeaaelldeeairr.................ggseDniTvv