Gene CG10827 in Drosophila melanogaster

Synonym: Dmel\CG10827, Dmel_CG10827, CG10827

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold AP
Superfamily AP
Family AP
Subfamily AP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP003_AA protein Get Run
DmelP003_AA_53-520 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_AP_pd Subfamily AP 60-519 2.3e-193 633.8 In-house 3-471 (472) alignment 
Range on Protein: 60-519
Range on HMM: 3-471/472.0
NAYWRQQGVQFVQQKLASEPNKRQAKNVILFLGDGMGVTTTSAARNLLG------GEEKSLSFENFPFTGLSKTYSVDKIVPDSACTATAYLCGVKGQEG
...|.... . ....|....|...||||||||||||||.|..||| | |      |||.||..|.||..|||||||.||.|||||.|||||||||| ..|
akfwlkkaqeelkealelqsnskkakNvilflgdGmgvstvtaaRilkgqlkgelgeeasLaleeFpyvglsktyssdkqvpdsaatAtAylcGvktnng

TIGVNGQVPRTDCKVMLdeSTHVDSIAKWAMEAGKWAGLVTTTRVTHASPSGVYAHIAERDWENDAEVATDCGaGSGINDIAYQLARGEVGSKLKVIMGG
||||. .| |.||. .   ...||||...|..|||..|||||||||||||.|.|||.|.|.||.|.|| ...   .|..|||.|| . |||..|.||.||
tiGvdaaverkdCeasa..gkevdsileaAkkaGkatGlVtttrvthAsPaglyahvanRnwesdeevpaeae.kegckdiaqQLieeevgkeldvilGG

GRKHFVDSSLESW-----GKRTDGLNLIDEFKSASENNVYVTTAAELAAVDVTKTDRLLGLFNDDHLQYLMETtTESSQPTLEQMTRKAIEYMSQNEQGY
|||.|.... ..      |.|.|| |||.|......|..||.. .|| .||..|||||||||.|.||.| ... .|...|.|..||.||.|..|.||.|.
GrkkflpktvkdseyekkgerkDgrnLieewekekknakyvenrkelenvdksktdrllGlfadshlkyeidr.dekeePsLkemtekAlevLsknenGf

FLFIEGGRIDQAHHINQARMALNETIEFSKAIAAAQELTSEDDTLLVVTADHSHVFTYAGYSYRGSDVFGKTP-VNGHDGKPYMVLSYANGPSYENFYD-
|||.||||||.||| |.|. ||.||.||..|...|.|||.|.|||.||||||||..|.|||..|||...| ..  . .|..||..|||||||.||.... 
fLfVEggrIDhahhenkakkaleetlefdeavelaleltdeedTlivvtaDHshtltiagypkrgssilglakesksadelpyttlsyangpgyeltesd

AETMERKDPTTVVKGDHDDEFPSGVPIDMDSHGGDDVPVYALGPWAHLFTGVYEQSTIPHMMAYASCLGDGHT
.|..||||.|.. ....| .... ||.. ..|||.|| ||| ||..||.|||.|||||.|.||||.|||...|
leegerkdlteaeteakdyvsqaavpleeetHggeDvavyasGpqshlltGvveqstiahvmayaaclgeaet
0037220 Alkaline phosphatase-like 60-520 9.4e-150 489.5 In-house 9-474 (479) alignment 
Range on Protein: 60-520
Range on HMM: 9-474/479.0
NAYWRQQGVQFVQQKLASEPNKRQAKNVILFLGDGMGVTTTSAARNLLG------GEEKSLSFENFPFTGLSKTYSVDKIVPDSACTATAYLCGVKGQEG
  ..... .... . |.  .||..|||||||.||||||.|..||| .||      |||. |....||..||.||||||..|.|||..|||...|||   |
lllllllalallllalllllnkskaknvilfigDGmgvstvtaariylgqllgglgeegllaldkfplvglvkTysvdslvtDSAaaaTAlatGvKtnng

TIGVNGQVPRTDCKVMLDesTHVDSIAKWAMEAGKWAGLVTTTRVTHASPSGVYAHIAERDWENDAEVATDCgAGSGINDIAYQLArgeVGSKLKVIMGG
.|||. .| |..|. .|.  ..|..|...| ||||. |||||||.|||.|...|||.|.|.||.|... .    ..|..|||.||    .||.|.||.||
aigvdadvsrdncddplg..npvetilelakeaGkatGlVtTtrithATPAafyAhvanRnweddialqllg.leagckdiatqlv...lgsgldvilGG

GRKHFVDSSLE---------SWGKRTDGLNLIDEFKSASENNVYVTTAAELAAVDV-TKTDRLLGLFNDDHLQYLMETtTESSQPTLEQMTRKAIEYMSQ
|||.|....             |||.|| .|..|.|.....  |||. .||.|.|. ...|.|||||.|.||.| ..    | .|.|..||.||....|.
GrkyflpkgtldpeydlelllggkrldgrdlleeakekkkgytyvtnreeldaldlgsnvdkllGlfadshlpyeldr.daseePsLaemtekAldlLsk

NEQGYFLFIEGGRIDQAHHINQARMALNETIEFSKAIAAAQELTSEDDTLLVVTADHSHVFTYAGYSYRGSDVFGKTPVNGHDGKPYMVLSYANGPSYEN
|..|.||..|||||| |.| | |..||.|...|..|..|| |....||||.||||||||.... ||..||....| .|    ||.||. |.|||||..  
ndkGFfLmvEggriDhagHandaaaalgevlafdeaveaalefakdddTlvvvtADHshgglilgyadrgnpilgllpgllldglpyttllyangpgfll

FYDAetmeRKDPTTVVKGDHDDEFPSGVPIDMDSHGGDDVPVYALGPWAHLFTGVYEQSTIPHMMAYASCLGDGHTM
..|     |.|.|..|  ...  ....|. . ..|.|.||||||.||.|.||.||||.. |.|..|.| .||  ...
lldl....rldltllvtlallllqralvgwtsggHtgedVpvyayGpgaelflgvyentdiahviasalglgllevl
Alk_phosphatase Alkaline phosphatase 84-514 1e-131 430.3 Pfam-A 1-421 (421) alignment 
Range on Protein: 84-514
Range on HMM: 1-421/421.0
AKNVILFLGDGMGVTTTSAARNLLGGEEKS-----LSFENFPFTGLSKTYSVDKIVPDSACTATAYLCGVKGQEGTIGVNgqvprtdckvmlDESTHVDS
||||||..||||||.|..|||.| ......     | ....|..||||||.||| |.|||.|||||.||||  .|.|||.            .. ..| |
aknvilligDGmgvstvtaaRslkeqakgklgeeilaldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevks

IAKWAMEAGKWAGLVTTTRVTHASPSGVYAHIAERDWENDAEVaTDCGAGSGINDIAYQLARGEvgSKLKVIMGGGRKHFVDSSLE----SWGKRTDGLN
. ..| .|||  |||||||||||.|....|| |.|.||.||.. ..  .  | .|||.|| . .   |..|..|||||.|.. . .    . | |.|| |
vleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaat.aasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgrn

LIDEFKSASenNVYVTTAAELAAVDVTK-TDRLLGLFNDDHLQYLMETtTESSQPTLEQMTRKAIEYMSQNEQGYFLFIEGGRIDQAHHINQARMALNET
||.|.|.|.    ||....||...   . .. |||||.|..|.. .|   |...|.|..||..||. .|.||.|.||..||.|||.|.| |.|  ||.|.
lieeakkag..yqyvsdrkeLlkakeensvkplLGLFadgdlkveler.dekeePsLkemtevAiklLsknekGFFLlVEGsrIDhaaHendavgalsEv

IEFSKAIAAAQELT-SEDDTLLVVTADHSHVFTYAGYSYRGSDVFGKTPVNG-HDGKPYMVLSYANGPSYENFYdaetMERKDPTTVVKGDHDDEFPSGV
.|| .|..||.|.. .|..||.||||||||||. .||. ||....| ....  .|||......|.||....        .|.. |.  ....  .. | |
vefdeAvkaalefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngegakved....garenvtaeealekiyrkrsav

PIDMDSHGGDDVPVYALGPWAHLFTGVYEQSTIPHMMAYASCL
... . |.|.||.|.| || |.|..||.|| .|....|.| .|
gltseeHtgedvavfAygpkaelvrGvqeqteiakvlaaalel
Alk_phosphatase Alkaline phosphatase 84-514 1e-131 430.3 In-house 1-421 (421) alignment 
Range on Protein: 84-514
Range on HMM: 1-421/421.0
AKNVILFLGDGMGVTTTSAARNLLGGEEKS-----LSFENFPFTGLSKTYSVDKIVPDSACTATAYLCGVKGQEGTIGVNgqvprtdckvmlDESTHVDS
||||||..||||||.|..|||.| ......     | ....|..||||||.||| |.|||.|||||.||||  .|.|||.            .. ..| |
aknvilligDGmgvstvtaaRslkeqakgklgeeilaldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevks

IAKWAMEAGKWAGLVTTTRVTHASPSGVYAHIAERDWENDAEVaTDCGAGSGINDIAYQLARGEvgSKLKVIMGGGRKHFVDSSLE----SWGKRTDGLN
. ..| .|||  |||||||||||.|....|| |.|.||.||.. ..  .  | .|||.|| . .   |..|..|||||.|.. . .    . | |.|| |
vleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaat.aasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgrn

LIDEFKSASenNVYVTTAAELAAVDVTK-TDRLLGLFNDDHLQYLMETtTESSQPTLEQMTRKAIEYMSQNEQGYFLFIEGGRIDQAHHINQARMALNET
||.|.|.|.    ||....||...   . .. |||||.|..|.. .|   |...|.|..||..||. .|.||.|.||..||.|||.|.| |.|  ||.|.
lieeakkag..yqyvsdrkeLlkakeensvkplLGLFadgdlkveler.dekeePsLkemtevAiklLsknekGFFLlVEGsrIDhaaHendavgalsEv

IEFSKAIAAAQELT-SEDDTLLVVTADHSHVFTYAGYSYRGSDVFGKTPVNG-HDGKPYMVLSYANGPSYENFYdaetMERKDPTTVVKGDHDDEFPSGV
.|| .|..||.|.. .|..||.||||||||||. .||. ||....| ....  .|||......|.||....        .|.. |.  ....  .. | |
vefdeAvkaalefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngegakved....garenvtaeealekiyrkrsav

PIDMDSHGGDDVPVYALGPWAHLFTGVYEQSTIPHMMAYASCL
... . |.|.||.|.| || |.|..||.|| .|....|.| .|
gltseeHtgedvavfAygpkaelvrGvqeqteiakvlaaalel
Metalloenzyme Metalloenzyme superfamily 320-402 6.2e-06 15.9 Pfam-A 113-196 (252) alignment 
Range on Protein: 320-402
Range on HMM: 113-196/252.0
ETTTESSQPTLEQM--TRKAIEYMSQNEQGyFLFIEGGRIDQAHHINQARMALNETIEFSKAIAAAQELTSEDDTLLVVTADHSH
| .| . .|.....  |.|..| . ...   |...    .|.. | ...  . .   .. ....   .  ...|.||..||||. 
egaTydlkpemsakeitdkllealekgkyd.fvvvnlantDmvGHtgdveakvkaieavDerlkelldavekeddlliitADHgn