Gene CG5361 in Drosophila melanogaster

Synonym: Dmel\CG5361, Dmel_CG5361, CG5361

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold AP
Superfamily AP
Family AP
Subfamily AP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP010_AA protein Get Run
DmelP010_AA_64-475 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0037220 Alkaline phosphatase-like 65-475 4.7e-55 177.7 In-house 6-469 (479) alignment 
Range on Protein: 65-475
Range on HMM: 6-469/479.0
ATSQKIWYDKGIDELNEALRPQ-DLTYPKNVRIFVIQGIDGRDWAAFRFPTSDASRG---NTNFIWDRFPHLARLKNSCSQQFPCQVASVSRALW-----
.... ...   .  |..||... . ...||| .|.  |..   ..| |. ...  .|   .. . .|.||...  |  ..... .  |. . ||.     
llllllllllalallllalllllnkskaknvilfigDGmgvstvtaariylgqllgglgeegllaldkfplvglvkTysvdslvtDSAaaaTAlatGvKt

----LGIPLDKVPDNQQDCGRlfnatQGPISILRQAQLAGLRTGFVTTQRITGPTGAAL--GNANGNFECDESMPLNSIKSGCQDIAQQLIsdeTGKFLN
    .|.  | ..|| .|. .     .   .||..|. ||..||.||| |||  | ||.   .|| |.|.|  ..|.....||.|||.||.   .|. |.
nngaigvdadvsrdncddplg.....npvetilelakeaGkatGlVtTtrithATPAafyAhvanRnweddialqllgleagckdiatqlv...lgsgld

VLIGGGRQ-MLSSLVPNTKYDPVDEMLCESNDGRNLLKDWRNQKLKeskinriiFDLIQRRDELESLNS-SSFDYLMGVMANGDLSG-----NSKAPSLK
|..||||. .|.. .....||... . .  .|||.||. ....| .        . ....|.||..|.. |..|.|.|..|...|.      .|. |||.
vilGGGrkyflpkgtldpeydlelllggkrldgrdlleeakekkkg........ytyvtnreeldaldlgsnvdkllGlfadshlpyeldrdaseePsLa

LMVDKSLNVLTKYKQGYLLIVEQfipSGIDKR-------------EQLQLLNDTLVNLHKDQDTLTLVL-----------------MTNAIYPKPSLDVS
 |..|.|..|.|...|..|.||.   . ||.              ...    .......||.|||..|                  ..  ..|.. ||. 
emtekAldlLskndkGFfLmvEg...griDhagHandaaaalgevlafdeaveaalefakdddTlvvvtADHshgglilgyadrgnpilgllpgllldgl

EETETI--------------SLLPEIFNEAESEIQKRLHQMPSES------LLFAQGPKSSIFQGVRKETFLAHAISHVLSRS
. |...                |. ..  |   .|. |....|..       ..|.||....|.||...|..||.| ..|. .
pyttllyangpgflllldlrldltllvtlallllqralvgwtsggHtgedVpvyayGpgaelflgvyentdiahviasalglg
subfamily_AP_pd Subfamily AP 67-412 1.8e-87 284.6 In-house 2-367 (472) alignment 
Range on Protein: 67-412
Range on HMM: 2-367/472.0
SQKIWYDKGIDELNEALRPQ-DLTYPKNVRIFVIQGIDGRDWAAFRFPTSD---ASRGNTNFIWDRFPHLARLKNSCSQQFPCQVASVSRALWLGIPLD-
|.|.|..|. .||.|||. | . .. ||| .|...|.. ....|.|. ...    .  .... ...||.....|...|... ...|....|.. |.  . 
sakfwlkkaqeelkealelqsnskkakNvilflgdGmgvstvtaaRilkgqlkgelgeeasLaleeFpyvglsktyssdkqvpdsaatAtAylcGvktnn

-----KVPDNQQDCGRLFnaTQGPISILRQAQLAGLRTGFVTTQRIT--GPTGAALGNANGNFECDESMPLNSIKSGCQDIAQQLISDETGKFLNVLIGG
     .  ....|| ..   ..   |||..|. || .||.|||.|.|  .|.|..  .|| |.|.||..| .. |.||.|||||||..|.||.|.|..||
gtiGvdaaverkdCeasa..gkevdsileaAkkaGkatGlVtttrvthAsPaglyahvanRnwesdeevpaeaekegckdiaqQLieeevgkeldvilGG

GRQML-SSLVPNTKYDPVdemlCESNDGRNLLKDWrnqkLKESKINRIIFDliqrRDELESLNSSSFDYLMGVMANGDLS-----GNSKAPSLKLMVDKS
||... .. |....|..     .|..|||||...|     ||.| ......    |.|||....|..|.|.|..|...|.      ....|||| |..|.
Grkkflpktvkdseyekk....gerkDgrnLieew....ekekknakyven....rkelenvdksktdrllGlfadshlkyeidrdekeePsLkemtekA

LNVLTKYKQGYLLIVE-QFIPSGIDKREQLQLLNDTL---------VNLHKDQDTLTLV------LMTNAIYPKPSLDVS
|.||.| ..|..|.|| ..|... ..... . |..||         ..|....|||..|       .| |.||| . .. 
levLsknenGffLfVEggrIDhahhenkakkaleetlefdeavelaleltdeedTlivvtaDHshtltiagypkrgssil
Alk_phosphatase Alkaline phosphatase 176-365 2.9e-28 89.5 Pfam-A 82-263 (421) alignment 
Range on Protein: 176-365
Range on HMM: 82-263/421.0
ATQGPISILRQAQLAGLRTGFVTTQRITGPTGAALGNANGNFECD--ESMPLNSIKSGCQDIAQQLISDEtgKFLNVLIGGGRQMLsslVPNTKYDPvDE
 ..   |.|..|. ||  || ||| |.|  | |||   . . ..     .. .  | |..|||.|||. .  | ..||.||||. .   .|... |.  .
hgkevksvleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaataasakkeGkkdiaeqlikak..kkidvllGGGrkef...lptgtkde.ek

MLCESNDGRNLLKDWrnqklkeskiNRIIFDLIQRRDELESLNSSS-FDYLMGVMANGDLSG-----NSKAPSLKLMVDKSLNVLTKYKQGYLLIVEQ
      ||||| ...           .  . ... | || . ...   ..|.|  |.|||       ... |||| |... ...|.| ..|. |.|| 
erGtrldgrnlieea..........kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvelerdekeePsLkemtevAiklLsknekGFFLlVEG
Alk_phosphatase Alkaline phosphatase 176-365 2.9e-28 89.5 In-house 82-263 (421) alignment 
Range on Protein: 176-365
Range on HMM: 82-263/421.0
ATQGPISILRQAQLAGLRTGFVTTQRITGPTGAALGNANGNFECD--ESMPLNSIKSGCQDIAQQLISDEtgKFLNVLIGGGRQMLsslVPNTKYDPvDE
 ..   |.|..|. ||  || ||| |.|  | |||   . . ..     .. .  | |..|||.|||. .  | ..||.||||. .   .|... |.  .
hgkevksvleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaataasakkeGkkdiaeqlikak..kkidvllGGGrkef...lptgtkde.ek

MLCESNDGRNLLKDWrnqklkeskiNRIIFDLIQRRDELESLNSSS-FDYLMGVMANGDLSG-----NSKAPSLKLMVDKSLNVLTKYKQGYLLIVEQ
      ||||| ...           .  . ... | || . ...   ..|.|  |.|||       ... |||| |... ...|.| ..|. |.|| 
erGtrldgrnlieea..........kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvelerdekeePsLkemtevAiklLsknekGFFLlVEG
subfamily_AP_pd Subfamily AP 442-475 3.5e-07 19.9 In-house 434-467 (472) alignment 
Range on Protein: 442-475
Range on HMM: 434-467/472.0
ESLLFAQGPKSSIFQGVRKETFLAHAISHVLSRS
 . ..|.||.|....|| .....||....... .
DvavyasGpqshlltGvveqstiahvmayaaclg