Gene CG8147 in Drosophila melanogaster

Synonym: 154821_at, BEST:LD38109, Dmel\CG8147, Dmel_CG8147, CG8147

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold AP
Superfamily AP
Family AP
Subfamily AP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP013_AA protein Get Run
DmelP013_AA_61-534 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0037220 Alkaline phosphatase-like 62-534 1.3e-149 489.0 In-house 5-472 (479) alignment 
Range on Protein: 62-534
Range on HMM: 5-472/479.0
EERYAEYWQGLAAQTLDQQLesKLRLNTQLARNVMLFIGDGMSIPTITAGRVYLG------GEEKQFAFEQFPYVGLSKTYCANMQVADSACTATAYLGG
.. .. ..  || ..| ..|  .| ||.. |.||.|||||||...|.|| |.|||      |||...|...||.|||.|||... .|.|||..|||.. |
lllllllllllalallllal..llllnkskaknvilfigDGmgvstvtaariylgqllgglgeegllaldkfplvglvkTysvdslvtDSAaaaTAlatG

VKANYGTIGVSAAVQFKDCQAQAQaaHHVSSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEVVGDNGDPDlCPDAAAQLInspVGQKL
||.|.|.|||.|.|....|... .  ..| .|. .|...|.||||||||..|||.||..||| ||||||.|...   . ... |.| | ||.   .|..|
vKtnngaigvdadvsrdncddplg..npvetilelakeaGkatGlVtTtrithATPAafyAhvanRnweddialqllgleag.ckdiatqlv...lgsgl

NVIMGGGRENFLPKGVTDSSGA-----PGRRLDGRNLIDEWKNQHTNsAQYVENRRELLNLS--NHTSRVLGLFAPYHMAYHLDASPAEQPTLEEMVQSA
.||.||||..|||||..|  .      .|.|||||.|..|.|..... ..|| ||.||..|.  ......|||||. |..|.|| ...|.|.|.||.. |
dvilGGGrkyflpkgtldpeydlelllggkrldgrdlleeakekkkg.ytyvtnreeldaldlgsnvdkllGlfadshlpyeldrdaseePsLaemtekA

MEILERqsAGRGYFLFVEGGRIDHGHHDTLALRAIDETAEFDKAVRFARSHTSTDDTLIVVSSDHSHTMSLAGYSSRKNDIFGINDGQlAADDLPYATLS
...|..    .|.||.||||||||..|.. | .|..|. .||.||..|.  .. ||||.||..||||.... ||..|.|.|.|. .|. ..|.|||.||.
ldlLsk..ndkGFfLmvEggriDhagHandaaaalgevlafdeaveaalefakdddTlvvvtADHshgglilgyadrgnpilgllpgl.lldglpyttll

YANGPGYDSNYLReggavrRKNLRAINMKNKDFMFPSTVPLESETHGGDDVAVFASGPYAQLFTGVFEQHFIPHALGYASCLSDRN
||||||.  ..        |..|  ... .........|...|..|.|.||.|.|.||.|.||.||.|...|.|.. .| .|.  .
yangpgflllldl......rldltllvtlallllqralvgwtsggHtgedVpvyayGpgaelflgvyentdiahviasalglglle
subfamily_AP_pd Subfamily AP 66-534 1.3e-197 647.8 In-house 3-470 (472) alignment 
Range on Protein: 66-534
Range on HMM: 3-470/472.0
AEYWQGLAAQTLDQQLESKlrLNTQLARNVMLFIGDGMSIPTITAGRVYLG------GEEKQFAFEQFPYVGLSKTYCANMQVADSACTATAYLGGVKAN
|..|. .|...|...||..   |.. |.||.||.||||.. |.||.|.. |      |||...|.|.||||||||||... ||.|||.||||||.|||.|
akfwlkkaqeelkealelq..snskkakNvilflgdGmgvstvtaaRilkgqlkgelgeeasLaleeFpyvglsktyssdkqvpdsaatAtAylcGvktn

YGTIGVSAAVQFKDCQAQAqaAHHVSSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEVVGDNGdPDLCPDAAAQLINSPVGQKLNVIM
.|||||.|||..|||.|.|  ...|.||...|.|.|.||||||||.||||||||.||| ||||||.|.||  ..  .. | | | |||...||..|.||.
ngtiGvdaaverkdCeasa..gkevdsileaAkkaGkatGlVtttrvthAsPaglyahvanRnwesdeevpaeae.kegckdiaqQLieeevgkeldvil

GGGRENFLPKGVTDSSGAP-GRRLDGRNLIDEWkNQHTNSAQYVENRRELLNL-SNHTSRVLGLFAPYHMAYHLDASPAEQPTLEEMVQSAMEILERQSa
||||..||||.|.||.. . |.| ||||||.|| ......|.|||||.||.|. ...|.|.|||||..|..|..|....|.|.|.||...|.|.|.... 
GGGrkkflpktvkdseyekkgerkDgrnLieew.ekekknakyvenrkelenvdksktdrllGlfadshlkyeidrdekeePsLkemtekAlevLskne.

gRGYFLFVEGGRIDHGHHDTLALRAIDETAEFDKAVRFARSHTSTDDTLIVVSSDHSHTMSLAGYSSRKNDIFGINDGQLAADDLPYATLSYANGPGYDS
 .|.|||||||||||.||.. | .|..||.|||.||. |...|...||||||..|||||...|||..|...|.|... . .||.|||.||||||||||..
.nGffLfVEggrIDhahhenkakkaleetlefdeavelaleltdeedTlivvtaDHshtltiagypkrgssilglakesksadelpyttlsyangpgyel

NYLREGGaVRRKNLRAINMKNKDFMFPSTVPLESETHGGDDVAVFASGPYAQLFTGVFEQHFIPHALGYASCLSDRN
.. ..    .||.|.......||......||||.|||||.||||.||||...|.|||.||..|.|.. ||.||....
tesdlee.gerkdlteaeteakdyvsqaavpleeetHggeDvavyasGpqshlltGvveqstiahvmayaaclgeae
Alk_phosphatase Alkaline phosphatase 92-530 3.7e-138 451.5 Pfam-A 1-421 (421) alignment 
Range on Protein: 92-530
Range on HMM: 1-421/421.0
ARNVMLFIGDGMSIPTITAGRVYLGGEEKQF-----AFEQFPYVGLSKTYCANMQVADSACTATAYLGGVKANYGTIGVSaavqfkdcqaqaQAAHHVSS
|.||.|.|||||. .|.|| | . .......     |....|.|||||||. . ||.|||.|||||. |||.. |.|||.            .  ..| |
aknvilligDGmgvstvtaaRslkeqakgklgeeilaldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevks

IAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEVvGDNGDPDLCPDAAAQLINSPvgQKLNVIMGGGRENFLPKGVTDSSGAPGRRLDGRN
.  .|.|.| .|||||||.||||.||...|| |.|.||.||.. ...   . ..| | |||. .  .|..|..||||..|||.| .|. .. | ||||||
vleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaat.aasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgrn

LIDEWknqHTNSAQYVENRRELLNLSNH--TSRVLGLFAPYHMAYHLDASPAEQPTLEEMVQSAMEILERQSagRGYFLFVEGGRIDHGHHDTLALRAID
||.|.   . ...|||..|.|||. ...  .. .|||||. .....|.  ..|.|.|.||...|...|....  .|.||.|||.||||..|.. | .|..
lieea...kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvelerdekeePsLkemtevAiklLskne..kGFFLlVEGsrIDhaaHendavgals

ETAEFDKAVRFARSHT-STDDTLIVVSSDHSHTMSLAGYSSRKNDIFGINDGQLAADDLPYATLSYANGPGYDSNYlreggaVRRKNLRAINMKNKDFMF
|. |||.||. |  .. . ..||.|| .||||..|..||. |...|.|.   .   |  ..  ..|.||.|.. .         |.|. | .. .| . .
EvvefdeAvkaalefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngegakved......garenvtaeealekiyrk

PSTVPLESETHGGDDVAVFASGPYAQLFTGVFEQHFIPHALGYASCL
 | |.|.||.|.|.|||||| || |.|..|| ||  |.. | .| .|
rsavgltseeHtgedvavfAygpkaelvrGvqeqteiakvlaaalel
Alk_phosphatase Alkaline phosphatase 92-530 3.7e-138 451.5 In-house 1-421 (421) alignment 
Range on Protein: 92-530
Range on HMM: 1-421/421.0
ARNVMLFIGDGMSIPTITAGRVYLGGEEKQF-----AFEQFPYVGLSKTYCANMQVADSACTATAYLGGVKANYGTIGVSaavqfkdcqaqaQAAHHVSS
|.||.|.|||||. .|.|| | . .......     |....|.|||||||. . ||.|||.|||||. |||.. |.|||.            .  ..| |
aknvilligDGmgvstvtaaRslkeqakgklgeeilaldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevks

IAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEVvGDNGDPDLCPDAAAQLINSPvgQKLNVIMGGGRENFLPKGVTDSSGAPGRRLDGRN
.  .|.|.| .|||||||.||||.||...|| |.|.||.||.. ...   . ..| | |||. .  .|..|..||||..|||.| .|. .. | ||||||
vleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaat.aasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkdeekerGtrldgrn

LIDEWknqHTNSAQYVENRRELLNLSNH--TSRVLGLFAPYHMAYHLDASPAEQPTLEEMVQSAMEILERQSagRGYFLFVEGGRIDHGHHDTLALRAID
||.|.   . ...|||..|.|||. ...  .. .|||||. .....|.  ..|.|.|.||...|...|....  .|.||.|||.||||..|.. | .|..
lieea...kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvelerdekeePsLkemtevAiklLskne..kGFFLlVEGsrIDhaaHendavgals

ETAEFDKAVRFARSHT-STDDTLIVVSSDHSHTMSLAGYSSRKNDIFGINDGQLAADDLPYATLSYANGPGYDSNYlreggaVRRKNLRAINMKNKDFMF
|. |||.||. |  .. . ..||.|| .||||..|..||. |...|.|.   .   |  ..  ..|.||.|.. .         |.|. | .. .| . .
EvvefdeAvkaalefakkeketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygngegakved......garenvtaeealekiyrk

PSTVPLESETHGGDDVAVFASGPYAQLFTGVFEQHFIPHALGYASCL
 | |.|.||.|.|.|||||| || |.|..|| ||  |.. | .| .|
rsavgltseeHtgedvavfAygpkaelvrGvqeqteiakvlaaalel