Gene CG31469 in Drosophila melanogaster

Synonym: CG9599, Dmel\CG31469, Dmel_CG31469, CG31469

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC2
Superfamily CC2
Family LMWPTP
Subfamily LMWPTP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP057_AA protein Get Run
DmelP057_AA_0-152 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0046251 Phosphotyrosine protein phosphatases I 1-152 6.9e-44 140.0 In-house 6-157 (159) alignment 
Range on Protein: 1-152
Range on HMM: 6-157/159.0
MKVLFVCIGNTCRSPMAEAILKHLVVKRNLQD--WYVDSAGLRSWNVGLEPQARGQQLLKQHGLKTNHLGRMISAQDFYDFDYIFAMDNSNLLELEHMAA
.||||||.||.||||||||.|.||. ...|.|  ..|||||.....|| .|  | ...||..|....| .| ....||..||.|.|||.||| .| ..| 
kkvlfvCtgNicRSpmAeallrhlledaglsdllievdSaGtsalhvgeppdpravavlkelgidlshrarqlteedfeefdlilamddsnlrdllrlap

SltpSPTCKIQLLGSYIGRKE--DEIIEDPYFiQGMGGFNAAYLQILESCERFLQH
.   ... |. ||....|. |  .  ..|||. .|. .| ... .| | .| .|..
g...dargkvllllefagllellhwdvpDPyy.ggleaFeevldlieeaveallek
0053360 Phosphotyrosine protein phosphatases I 1-152 3.1e-42 134.4 In-house 6-155 (157) alignment 
Range on Protein: 1-152
Range on HMM: 6-155/157.0
MKVLFVCIGNTCRSPMAEAILKHLVVKRNLQD-WYVDSAGLRSWNVGLEPQARGQQLLKQHGLKTNHLGRMISAQDFYDFDYIFAMDNSNLLELEHMAAS
.||||||.||.||||||||.|.||. ...|.| ..|||||.....|| ..  | ...|...|....| .| ....|...||.|..||.||| || ... .
kkvLfvCtgNicRSpmAeallrhlleeaglgdrfevdSaGtsalhvggpvdpravevlaelgidlshrarqlteedleefdliltmddsnleellplfpg

LtPSPTCKIQLLGSYIGRkEDEIIEDPYfIQGMGGFNAAYLQILESCERFLQH
|  ... |. ||....|. ..  ..|||  .|. .| ... .| | .| .|..
l.leakgkvllllefagl.lhwdvpDPy.yggleafelvldlieeaveallel
0048765 Phosphotyrosine protein phosphatases I 1-152 3.6e-42 134.2 In-house 3-152 (154) alignment 
Range on Protein: 1-152
Range on HMM: 3-152/154.0
MKVLFVCIGNTCRSPMAEAILKHLVVKRNLQD-WYVDSAGLRSWNVGLEPQARGQQLLKQHGLKTNHLGRMISAQDFYDFDYIFAMDNSNLLELEHMAAS
.||||||.||.||||||||.|.||. ...|.| ..|||||.....|| ..  | ...|...|....| .| ....|...||.|..||.||| || ... .
kkvLfvCtgNicRSpmAeallrhlleeaglgdrvevdSaGtsayhvgepvdpravevlaelgidlshrarqlteedleefdliltmddsnleellplfpg

LtPSPTCKIQLLGSYIGRkEDEIIEDPYfIQGMGGFNAAYLQILESCERFLQH
|  ... |. ||....|. ..  ..|||  .|. .|.... .| | .| .|..
l.leakgkvllllefagl.lhwdvpDPy.yggleafeevldlieeaveallel
0042188 Phosphotyrosine protein phosphatases I 1-152 5.9e-38 120.4 In-house 5-142 (146) alignment 
Range on Protein: 1-152
Range on HMM: 5-142/146.0
MKVLFVCIGNTCRSPMAEAILKHLVvkrnlQD-WYVDSAGLRSWNVGLEPQARGQQLLKQHGLKTN-HLGRMISAQDFYDFDYIFAMDNSNLLELEHMAA
.||||||.||.||||||||.|.||.     .| ..|||||.....|| ..  | ...|...|.... |  | ....|. .||....||.||| .| ... 
kkvlfvCtgNicRSpmAeallrhll.....gdrvevdSAGtsayhvgepvdpravevlaelgidisghrarqlteedleefDlvltmddsnlrdllplfp

sltPSPTCKIQLLGSYIgrkedeIIEDPYfI-QgmGGFNAAYLQILESCERFLQH
   . .. |. ||....       ..|||       .| ... .| | ....|..
...gaakgkvllllefw......dvpDPy.ygg..eafeevldlieeavkallel
LMWPc_SSU72_ArsC 1-128 1.6e-32 103.0 In-house 1-113 (126) alignment 
Range on Protein: 1-128
Range on HMM: 1-113/126.0
MKVLFVCIGNTCRSPMAEAILKHLVVKrnlqDWYVDSAGLRSWNVGLEPQARGQQLLKQHGLKTNHLGRMISAQDFYDFDYIFAMDNSNLLELEHMAASL
.|||||| ||.||||||||.||..| |    .. |.|||. ....| ....| ..|||..|....|  | ....|. .||.|..||..|  |. ... . 
kkvlfvClgNicRSpmAeavlkkavkk....glnvsSaGtgaavpgksidsravellkengielkhkprqlqeedlkefdliltmdernkdevlellper

tpsPTCKIQLLgsyigrkeDEIIEDPYF
    | |..||        .  ..||| 
...atkkvhll........nldvkDpye
0047618 Phosphotyrosine protein phosphatases I 1-152 2e-31 99.0 In-house 2-135 (137) alignment 
Range on Protein: 1-152
Range on HMM: 2-135/137.0
MKVLFVCIGNTCRSPMAEAILKHLVVKRnlqdWYVDSAGLRSWNvglePQARGQQLLKQHGLKTN-HLGRMISAQDFYDFDYIFAMDNSNLLELEHMAAS
.||||||.||.||||||||.|.||. .|    ..|||||.....    .  | ...|...|.... |  . ....|...||....||.|.| .| ..| .
kkvlfvCtgNicRSpmAeallrhllgdr....vevdSAGtepag....vdpravevlaelgidisghrskqldeldlpefdlvltmddsalealpllapa

LTPSPTckiqllgsyigrkedeIIEDPYFIQG-----MGGFNAAYLQILESCERFLQH
 .                     ..|||...|     . .|  .. .| | .| .|..
alrlhw................dvpDPyygggteeekleafervldlieerveallel
0047572 Phosphotyrosine protein phosphatases I 1-150 4.8e-29 91.2 In-house 3-128 (130) alignment 
Range on Protein: 1-150
Range on HMM: 3-128/130.0
MKVLFVCIGNTCRSPMAEAILKHLVvkrnLQDWYVDSAGLRswnvGLEPQARGQQLLKQHGLKT-NHLGRMISAQDFYDFDYIFAMDNSNLLELEHMAAS
.||||||.||.||||||||.|.||.     ....|.|||..    | ..  | ...|...|... .|  . ........||....||.|.| .| ..| .
kkvlfvCtgNscRSpmAeallrhll....gdrvevySAGte....gsgvdpravevlaelgidisghrskqldelllpefdlvitmddsalealpllapa

LTPSPTckiqllgsyigrkedeIIEDPYfIQGMGGFNAAYLQILESCERFL
 .                     |.|||  .|. .| ... .| . .. .|
alrlhw................dipDPy.gggleafrevrdlierrvlall
LMWPc_SSU72 1-150 4.6e-26 82.3 In-house 1-135 (137) alignment 
Range on Protein: 1-150
Range on HMM: 1-135/137.0
MKVLFVCIGNTCRSPMAEAILKHLVVkrnlqDWYVDSAGLRSWNVGLEPQARGQQLLKQHGLKTNHLGRMISAQDFYDFDYIFAMDNSNLLELEHMAASL
.||||||..|..||..|||.||. .       . |.|||..|. .| ... . ..|.|..||....  . ...... .||.......... ..  .. . 
lkvlfVCasNinRSmeAeallkeale.....glevkSaGtgslvpgpsidkpaeelykenGlsikeapeklqeeelekfDlvitleervfdavvedlper

tpS----PTCKIqllgsyigrkeDEIIEDPYFIQgMGGFNAAYLQILESCERFL
  |    ... |           .  |.||.  . . ||.|.. .| |... .|
..selkrkvhvi...........nvdikDpheea.iegfkaildlieervkell
subfamily_LMWPTP_pd Subfamily LMWPTP 2-152 3.2e-65 208.6 In-house 3-151 (152) alignment 
Range on Protein: 2-152
Range on HMM: 3-151/152.0
KVLFVCIGNTCRSPMAEAILKHLVVKRNLQ-DWYVDSAGLRSWNVGLEPQARGQQLLKQHGLKTNHLGRMISAQDFYDFDYIFAMDNSNLLELEHMAASL
||||||.||.||||.|||.|..||.|..|. || ||||...|..|| ||..|....||.||||..| .|.|...|| .||||.|||.||| ||...|.. 
kvlfvClGniCrspiaEavlrklvekkglkedwkvdsaaissyhvGkepdkRalsilkkhglksshrarqitkedfsefdyilamDesnlkelkklakek

TPSPtCKIQLLGSYIgRKEDEIIEDPYFiQGMGGFNAAYLQILESCERFLQH
. |  .|..|||.|  .|..|||||||. ...  |.|.| || |.|..||..
kesk.akvlllgeyd.kkgkeiiedpyy.gdekdFeavykqikecckaflkk
0051181 Phosphotyrosine protein phosphatases I 2-151 2.2e-31 98.7 In-house 1-123 (124) alignment 
Range on Protein: 2-151
Range on HMM: 1-123/124.0
KVLFVCIGNTCRSPMAEAILKHLVVKrnlqdWYVDSAGLrswNVGLEPQARGQQLLKQHGLKTNHLGRMISAQDFYDFDYIFAMDNSNLLELEHMAAslt
||||||.||.||||||||.|.||. .     ..|||||.   ..| ..  | ...|...|.....  . ....|. .||....||.|||  | ..|    
kvlfvCtgNicRSpmAeallrhllgd.....vevdSAGt...hpggpvdpravevlaelgidlslrskqldeldleefdlvltmddsnlcpllplap...

psptckiqllgsyigRKEDEIIEDPYfIQGMGGFNAAYLQILESCERFLQ
               . ..  ..|||  .|. .| ... .| | .| .|.
...............lllhwdvpDPy.yggleefeevldlieervealle
subfamily_Sponge-LMWPTP-like_pd Subfamily Sponge-LMWPTP-like 2-28 5.3e-07 19.4 In-house 2-28 (173) alignment 
Range on Protein: 2-28
Range on HMM: 2-28/173.0
KVLFVCIGNTCRSPMAEAILKHLVVKR
|.|||| ||.||||||  . ...  .|
kllfvcsgnscrspmamivaekmeaer
LMWPc Low molecular weight phosphotyrosine protein phosphatase 3-150 1.4e-36 116.5 Pfam-A 1-138 (138) alignment 
Range on Protein: 3-150
Range on HMM: 1-138/138.0
VLFVCIGNTCRSPMAEAILKHLVVKRNLQDWYVDSAGLRSWnVGLEPQARGQQLLKQHGLKTN-HLGRMISAQDFYDFDYIFAMDNSNLLELEHMAASlt
|||||.||.||||||||.|..|. |.  ... |||||.... || ... | ...||..|.... |..| .|.... .||.|...|.... ||...| .  
vlfvCtgNicRSpmAeallrallekalgdkvevdSAGteal.vgesvdpravevlkekgidisghrarqlseeelkefDliltldeeaarelcpvape..

pSPTCKIQLLGSyigrkeDEIIEDPYfIQGMGGFNAAYLQILESCERFL
   . |. |||.      .  |.|||  ...  |.. . .| |... .|
.kkeakvvllge......qwdipDPy.gkeeeefeevrdeieervkkll
LMWPc Low molecular weight phosphotyrosine protein phosphatase 3-150 1.4e-36 116.5 In-house 1-138 (138) alignment 
Range on Protein: 3-150
Range on HMM: 1-138/138.0
VLFVCIGNTCRSPMAEAILKHLVVKRNLQDWYVDSAGLRSWnVGLEPQARGQQLLKQHGLKTN-HLGRMISAQDFYDFDYIFAMDNSNLLELEHMAASlt
|||||.||.||||||||.|..|. |.  ... |||||.... || ... | ...||..|.... |..| .|.... .||.|...|.... ||...| .  
vlfvCtgNicRSpmAeallrallekalgdkvevdSAGteal.vgesvdpravevlkekgidisghrarqlseeelkefDliltldeeaarelcpvape..

pSPTCKIQLLGSyigrkeDEIIEDPYfIQGMGGFNAAYLQILESCERFL
   . |. |||.      .  |.|||  ...  |.. . .| |... .|
.kkeakvvllge......qwdipDPy.gkeeeefeevrdeieervkkll