Synonym: Dmel\CG9801, Dmel_CG9801, CG9801
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_tipA_pd | Subfamily tipA | 271-354 | 3.1e-10 | 29.3 | In-house | 4-81 (296) | alignment | ||
Range on Protein: 271-354
Range on HMM: 4-81/296.0
EPMGNPIADCYGMVVRGDSAAMAMADGVNWGDGARLAARSAVHGCLDYLDRAvfgqalECRATTTQEVFVSLLRSLWEGHGCIL
. |.|||| . ..|. . . .|.||| ||| . ||..|. . .|.| .. . .| ... ||... . | |.
kregdpiadrftvqvyknrlivaladGcnWGkrPaeaatnasaafvdflsek......sseintvkdaGkfllsafeaahkkiv
|
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subfamily_CG9801_pd | Subfamily CG9801 | 274-467 | 1.4e-67 | 217.7 | In-house | 3-219 (252) | alignment | ||
Range on Protein: 274-467
Range on HMM: 3-219/252.0
GNPIADCYGMVVRGDSAAMAMADGVNWGDGARLAARSAVHGCLDYLDRAVFGQAlecraTTTQEVFVSLLRSLWEGHGCILEVGGAL-----STLTIAVV
|.||||....||| .....|.|||.|||.....|||||.....|||..|.. .. ||.|||. |||..|.|.| .|.|....| .||...|.
GdPiaDkftvvvrknrlilalaDGcnWGerpaeaarsasaafidylskalskei.....ttvqevgksllaaleeahksivegkselweaGtttLlggvl
LPLDG-----------------------APGKYVVCSCNVGDSLGYVYS-KKHGVRELTQASHdiSSMRDMRDALGALGP-ADGNKPELSNLTFSMTCIE
|.|. ...|.......|||.....|| ||..|...|.... |...|.|||.|.||| ....||.|.||....|..|
lelekeaekpesssqlgksevglsasnassskwgfvcasvGDckaflysakkkevtditkgnr..snlsDarDagGrLGPyveqgkPdLrnLklfftlve
SGDIVFLTSDGISDNFDPVVGKFA
..||..|.|||..||.||.. ...
eeDiillvsDGvhDnlDPqtlgkt
|
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subfamily_CG9081_pd | Subfamily CG9081 | 274-463 | 2.5e-61 | 197.3 | In-house | 2-192 (195) | alignment | ||
Range on Protein: 274-463
Range on HMM: 2-192/195.0
GNPIADCYGMVVRGDSAAMAMADGVNWGDGARLAARSAVHGCLDYLDRAVFGQALecrATTTQEVFVSLLRSLWEGHGCILEVGGALSTLTIAVVLPLDG
|.|.|| ...|.| ..| ||.||||||| |||||||||.|...||. .|. . .......| ||.|| | . .||| .|.|.||.|||| |..
gePvadvfavvarennaimaladGvnWGkkarlaarsavagavaylndklfklsa...kpnsrdlfklllesleeaqksilensgtlttlsiavvcelka
A---PGKYVVCSCNVGDSLGYVYSKKHG-VRELTQASHDISSMRDMRDALGALGPADGNKPELSNLTFSMTCIESGDIVFLTSDGISDNFDPVV
...... .||||. .|||.... |||.| |||. .||.|.. ||||||.|..|.|.||..|.. ...||||||||||.||||||||
nkkissqWglfvvsvGdspvfvyspdnksvrevtvashskdgirdvrlsGGalGpaiGtdpdlenlslsylpvaeGdivfltsdGvsdnfdPvv
|
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subfamily_Sponge-PPM-1_pd | Subfamily Sponge-PPM-1 | 274-465 | 1.4e-54 | 174.7 | In-house | 2-195 (199) | alignment | ||
Range on Protein: 274-465
Range on HMM: 2-195/199.0
GNPIADCYGMVVRGDSAAMAMADGVNWGDGARLAARSAVHGCLDYLDRAVFGqaLECRATTTQEVFVSLLRSLWEGHGCILEVGGALSTLTIAVVLPL--
|.|.|| ...|.| ..| ||.||||||| .|||||.||.| . |. .|. |... |...... || || | | .||| .|.|.||.|||| |
GepvadvfavvarennaimaiadGvnwGkkprlaarcavqgaiayisdnlfk..lsakptnsrtltklllesldeahksileheGtlttlsiavvcelkp
-DGAPGKYVVCSCNVGDSLGYVYSKK-HGVRELTQASHDISSMRDMRDALGALGPADGNKPELSNLTFSMTCIESGDIVFLTSDGISDNFDPVVGK
. . ...... |||| .||| . . |.| | | || .|..|.. |||||| |..|.|.||..|. .. ||||.||.|||||||.||| |
nsrsssrwglfvasvGdspvfvyspdtksvheatvachdkdGirtarlsGGalGpaiGtdpdlenlslsylpvaeGdivllttdGisdnfapvvlk
|
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0034914 | PP2C-like | 274-460 | 5.7e-09 | 28.5 | In-house | 32-245 (295) | alignment | ||
Range on Protein: 274-460
Range on HMM: 32-245/295.0
GNPIADCYGMVV-----RGDSAAMAMADGVNWGDGARLAARSAVHGCLDYLDRA--VFGQALECRATTTQEVFVSLLRSLWEGHGCILEVGGALSTLTIA
.. |.. .|. .| . ....||.. . |..|.. .|. |..| . || .. ...|... . |.| |. | .|...|
rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallrpelagsGtTavva
VVlpLDGapgkyVVCSCNVGDSLGYVYSKKhgvrELTQASHDISSMRDMR--------------------DALGALGPADGN--------------KPEL
.. .. . .||||| ...... ||.| ..| . .. . ||| | |..
li..rgn.....klyvanvGDSravllrng....elvqltvdhkpvnelererilsaggavshgrvngvlavtRalGdfdlklllslllleplvsaePdv
SNLTFSmtcIESGDIVFLTSDGISDNFD
. |... .|..|.. | |||..|...
tvlelt...ledddfllLasDGlwdvls
|
|||||||||
0049733 | PP2C-like | 279-461 | 7.4e-14 | 44.9 | In-house | 20-194 (235) | alignment | ||
Range on Protein: 279-461
Range on HMM: 20-194/235.0
DCYGMvvrgDSAAMAMADGVNWGDGARLAARSAVHGCLDYLDRavfgqalecraTTTQEVFVSLLRSLWEGHGCI-------LEVGGALSTLTIAVVLpl
|.. . . . .|.|||.. . ....|.. .|. |..| . ... .. .| ..... . .. |. | .|...|..
Davlv....glllfavaDGhgghaagevasellvetllellle...........lllldleealrkaflaaneallelalaspelagmgtTavvalld..
dgapgKYVVCSCNVGDSLGYVYSKKhgvrELTQASHDISSMRDMRDA-----------------LGALGpA---DgnkpelsnLTFSMTCIESGDIVFLT
. .. .||||| |..... .|.| ..| | .... .. . ||| . .... .|.||...|.
.....ggklyvanvGDsrayllrdg....klvqltedhspvnelerqriitaggavrvpgrlaltralG.dlllk........pdvtvlelepgdfllla
SDGISDNFDP
|||..|....
sDGlwdvlsd
|
|||||||||
PP2C_2 | Protein phosphatase 2C | 279-461 | 3.7e-11 | 35.7 | Pfam-A | 14-183 (212) | alignment | ||
Range on Protein: 279-461
Range on HMM: 14-183/212.0
DCYGMVVRGDSAAMAMADGVNWGDGARLAARSAVHGCLDYLDRAVFGQALECRATTTQEVFVSLLRSL---WEGHGCILEVGGALSTLTIAVVLPldgap
| ... . | .|.|||. ... .|| ||. ...| . . .... ... ... .|.|. | . |. .||..||. |
DalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllavitp.....
gkYVVCSCNVGDSLGYVYSKKHGVRELTQ-ASHDISSMrdmrdalgaLGPADGNKPELSNLTFSMTcIESGDIVFLTSDGISDNFDP
. ......||. .|... . |. |.. .|...... . .. ...| . . ... |.|| ..|..||.||.. .
..geivffqiGDgaivvrdrdgevqllgepdsgeyane.........ttfltsedaeeelrirrlk.lepgdalllmTDGvsdslrk
|
|||||||||
PP2C_2 | Protein phosphatase 2C | 279-461 | 3.7e-11 | 35.7 | In-house | 14-183 (212) | alignment | ||
Range on Protein: 279-461
Range on HMM: 14-183/212.0
DCYGMVVRGDSAAMAMADGVNWGDGARLAARSAVHGCLDYLDRAVFGQALECRATTTQEVFVSLLRSL---WEGHGCILEVGGALSTLTIAVVLPldgap
| ... . | .|.|||. ... .|| ||. ...| . . .... ... ... .|.|. | . |. .||..||. |
DalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllavitp.....
gkYVVCSCNVGDSLGYVYSKKHGVRELTQ-ASHDISSMrdmrdalgaLGPADGNKPELSNLTFSMTcIESGDIVFLTSDGISDNFDP
. ......||. .|... . |. |.. .|...... . .. ...| . . ... |.|| ..|..||.||.. .
..geivffqiGDgaivvrdrdgevqllgepdsgeyane.........ttfltsedaeeelrirrlk.lepgdalllmTDGvsdslrk
|
|||||||||
PP2C_SIG_SM00331 | 279-458 | 2e-10 | 33.6 | In-house | 19-163 (217) | alignment | |||
Range on Protein: 279-458
Range on HMM: 19-163/217.0
DCYGMVVRGD-SAAMAMADGVNWGDGARLAARSAVHGCLDYLDRAvfgqalecraTTTQEVFVSLLRSLWEGhgciLEVGGALSTLTIAVVlplDGAPGK
| |..| .. . ... |||. | | .|...... .|.. ....... | | . | |..| ||..|.. | . ||
DyydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellseg..........eelsqalkrlnraiyee....keekgmfaTlllaly...dfssgk
YVVcsCNVGDSLGYVYSkKHGVRELTQAshdissmrdmrdalgALGPADGNKPELSnLTFSMTCIESGDIVFLTSDGISDN
. .|.||| |.. ... | ... .|.. | .||.| .. ... .| ||...| .||. ..
lsy..anaGdsrpyllr.dgklveilkd...............vegaplGlepevs.vdirelelekgdllllytDGltea
|
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subfamily_tipA_pd | Subfamily tipA | 375-465 | 5.4e-15 | 44.9 | In-house | 150-241 (296) | alignment | ||
Range on Protein: 375-465
Range on HMM: 150-241/296.0
PGKYVVCSCNVGDSLGYVYSKK-HGVRELTQASHdiSSMRDMRDALGALGPA-DGNKPELSNLTFSMTCIESGDIVFLTSDGISDNFDPVV-GK
. |.. . ||| . .||| . | ..|. | . | .|. | ||| . ||.| ||. .. .| ||..| |||. ||.|| ||
sskWgfvcasvGdckafllskkskevtditkgnr..snvddakdpGGrlGPyveqGkPdlrnlklffllceeediillvsdGvhdnldPktlgk
|