Gene CG17598 in Drosophila melanogaster

Synonym: Dmel\CG17598, PP2C, Dmel_CG17598, CG17598

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PPM1H
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP134_AA protein Get Run
DmelP134_AA_83-506 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0034914 PP2C-like 84-506 1.5e-49 161.4 In-house 8-290 (295) alignment 
Range on Protein: 84-506
Range on HMM: 8-290/295.0
IIVPRDINLLPWGTGYAECVNSGKSEWNEDQGAFCRQVLSDPEHkhpdlpYTYFGIFDGHAGYGAALAASHQFHHILHEKLVDCLELLLPRdadatnggg
.. .. ...|.. . .. . . |... |||.  .....||. |.      ...||.|||| |. ||  ||. ....|.| |  .| || .          
llellllsslllllrvgvasdqGrrksneDavlvvlnllslled......lllfgvfDGhgGhaaaevasellvelllellekllllltls.........

egnklnptfphpiyfqrrvtkDELIIGALESAFFNMDSLIAQDCDR--YRDAGGCTACVSLFIDGKMYVANAGDSRAVLCQRRATperpqtntdsgiepd
                     .| |. ||..|| ..|  . . . .  ... .|.||.| |....|.||||.|||||||. .                  
.....................ledieealrkaflaadeellelallrpelagsGtTavvalirgnklyvanvGDSravllrngel...............

pleascypVPFSADHTP--ETERERLLNVArlkphlmgkhyvameyakrphikdmgqrilcrqgtmrgwtyktltmedlcmpvvnGEGKRSRLLGTLGVT
        |. . ||.|  |.||||.|.                                                         |    .|..|.| ||
........vqltvdhkpvnelererilsag.......................................................gavshgrvngvlavt

RGFGDHELLAINTGIQIKPFLTPHPDVRQRDLTQvvsipdednrdGDYGVLVMATDGLWDVSENDAVSRTVFQTLSkystEKHRYTMVAQELVARARGki
| .||..|. ... ....|.....|||....||            .|. .|..|.|||||| .|. . . | ..|.    . . ....|.||| .|    
RalGdfdlklllslllleplvsaePdvtvleltl...........edddfllLasDGlwdvlsneeivdivrslla....kgldleeaaeeLvdlAla..

ndsghwrladskaAATVDDISVIVIPV
             .   |.|.|.|. .
.............rgsrDNiTvvvvrl
subfamily_PPM1H_pd Subfamily PPM1H 85-507 1.8e-178 586.4 In-house 1-403 (404) alignment 
Range on Protein: 85-507
Range on HMM: 1-403/404.0
IVPRDINLLPWGTGYAECVNSGKSEWNEDQGAfCRQVLSDPEHKHPD-------------LPYTYFGIFDGHAGYGAALAASHQFHHILHEKLVDCLELL
.|||... ||| .||||..|.||||.||||.| ....|.. |.|. .             ||..|||.||||||.||||.||...|..|.||| |.||||
lvprelrrlPwaaGYaevinagkselneDqaa.akvlllkkekkeksvtskpkekseeeklplayfglfDGhaGsgaalvaskllhkhlkekledvlell

LPRDADATNGGGEGNKLNPTFPHPIYFQRRVTKDELIIGALESAFFNMDSLIAQDCDRYRDAGGCTACVSLFIDGKMYVANAGDSRAVLCQRRATperpq
| ..|.......| .| .|.....||......|.||.||||||||..||..||.....||..|||||.|.|...||.||||||||||.|......     
leksaeeeenteesskespssvseiyeekeiskeeLviGalesaflemDeqiarereayrikGGCtalvalvllgklYvanaGDsRailvrkdei.....

tntdsgiepdpleascypVPFSADHTPETERERLLNVARLKPHLMGKHYVAMEYAKRPHIKDMGQRILCRQGTMRGWTYKTLTMEDLCMPVVNGEGKRSR
                  .|.|||.||||||.||...|.|||.|.||.....|..|| ..||.|||.|.|. .|.||.|||...|||..|...||||..|
..................iplsadftPeteRqRlqelaflkPeLlgkeftrlefqkRlkkkdlgqrvlyRdqnmtGWayktveeeDlkfplisgegkkaR

LLGTLGVTRGFGDHELLAINTGIQIKPFLTPHPDVRQRDLTQVVSIPDEdnrdgdygVLVMATDGLWDVSENDAVSRTVFQTLSKYS-TEKHRYTMVAQE
||.|.|||||.||||| ...|...|||||.|.|.||..||||| |..|.        ||..||||||||..|..|...| ..|||.. ..|.|||.||||
llatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDd........vlilatDGLWdvlsneevaeivrevlskvepedkkrytavaqe

LVARARGKINDSGhWRlADSKAAATVDDISVIVIPVC
|||.||||..|.| || .....||.||||||.|||..
LvaaarGklkdkg.Wr.lkeekaasvDDisvfviPlk
0049733 PP2C-like 99-505 3.7e-30 98.1 In-house 5-232 (235) alignment 
Range on Protein: 99-505
Range on HMM: 5-232/235.0
YAECVNSGK-SEWNEDQGAFcrqvlsdpehkhpdlPYTYFGIFDGHAGYGAALAASHQFHHILHEKLVDclelLLPRDadatngggegnklnptfphpiy
.. .   |.  ..|||  ..                ...|...||| |. |.  ||......|.| | .    ||. |                      
vgaasdigrvrkvneDavlv...............glllfavaDGhgghaagevasellvetllellle....lllld......................

fqrrvtkdelIIGALESAFFNMDSLIAQDCDRY--RDAGGCTACVSLFIDGKMYVANAGDSRAVLCQRRATperpqtntdsgiepdpleascypVPFSAD
          .. ||..||  ... . . . ..  .. .|.||.| |...||.||||.|||||.|...                          |. . |
..........leealrkaflaaneallelalaspelagmgtTavvalldggklyvanvGDsrayllrdgkl.......................vqlted

HTPETERERLLnvarlkphlmgkhyvameyakrphikdmgqrilcrqgtmrgwtyktltmedlcmpvVNGEGKRSRLLGTLGVTRGFGDHELLaintgiq
|.|  | ||                                                          .  .| . | .| | .|| .||..|        
hspvnelerqr........................................................iitaggavrvpgrlaltralGdlllk.......

ikpfltphpdvrqrdltqvVSIPDEDNRDGDygVLVMATDGLWDVSENDAVSRTVFQtlskystekHRYTMVAQELVARARGkindsghwrladskaAAT
                   . .   . ..||  .|..|.|||||| ... . ... .         . . ..|..|| .|.                . .
...................pdvtvlelepgd..flllasDGlwdvlsdeeivdllrs.........ldleeaaerlvelala...............rgg

VDDISVIVIP
 |.|.|.|. 
rDNiTvvvvr
subfamily_PPM1D_pd Subfamily PPM1D 120-480 7e-18 57.7 In-house 21-291 (309) alignment 
Range on Protein: 120-480
Range on HMM: 21-291/309.0
QVLSDPEHKHPDLPYTYFGIFDGHAGYGAALAASHQFHHILHEKlvdcLELLLPRDADAtngggegnklnptfphpiyfqrrvtkdeliIGALESAFFNM
.. ...|..  .| ......|||| |  ||  |...  . ....     ..|   ..|                               . |...||...
aivleeeesaeelevafvavfDGHGGkeAakfarehlwsvikkq....kkflssepedv..............................leAireaflat

DSLIAQ-------DCDRYRDAGGCTACVSLFIDGKMYVANAGDSRAVLCQRRAtperpqtnTDsgiepdpleASCYPVPFSADHTPETERERlLNVARLK
 . . .         . .    | || | .. . |.|||. |||..|| ..          ..          .  . .   || ||. .|.  ....| 
heamkkkleeWpktksgllstaGttasvviirreklyvahvGDsaivlgvkep........ke.........kklrakeltkdHkPespeek.erieelG

PHLMGKHYVAMEYAKRPHikdmgqrilcrqgtmrgwtyktltmedlcmpvV--NGEgKRSRLLGTLGVTRGFGDHELLAINTGIQIkpfLTPHPDVRQRD
 ... |. |     |||.                                .  ||. .    .  | |.|  ||      ..|  .     |.||| .| 
GevaaksGvkRvvWkRpr................................lehngp.tvideiPFLavaRslGDlWsynaksgefv...vsPePdvkvrt

LTqvvsiPDEDNrdgdygVLVMATDGLWDVSENDAVSRTVFQTLSKYSTEKHRYTMVAQELVARARGKIN
|.     |.|..      ....|.||||.| . ... ..| .. .| ...... . ||. || .| .. .
ld.....pneek......fiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvkealqrwr
PP2Cc_SM00332 125-504 4.8e-42 137.2 In-house 35-274 (274) alignment 
Range on Protein: 125-504
Range on HMM: 35-274/274.0
PehkhPDLPYTYFGIFDGHAGYGAALAASHQFHHILHEKLVDCLELLlprdadatngggegnklnptfphpiyfqrrvtkDELIIGALESAFFNMDSLIA
     .    ..||.||||.|  .|  .| .....|.|.|   .. |                                 .. .  ||..|| ..|. | 
v....eeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel.................................eddveealkkaflstdeeil

QDCDRYRD---AGGCTACVSLFIDGKMYVANAGDSRAVLCQRRAtperpqtntdsgiepdpleascyPVPFSADHTP--ETERERLLNVARlkphlmgkh
.. .. ..     |.||.|.|. ....||||.||||||||. .                         |. | ||.|  |.||.|. . .          
eeeqskelenalsGstavvallkkedlyvanvGDSravlcrngk.......................avqlsvdhkpedederkRikkagg.........

yvameyakrphikdmgqrilcrqgtmrgwtyktltmedlcmpV-VNGegkrsRLLGTLGVTRGFGDHELLAINtgIQIKPFLTPHPDVRQRDLtqvvsip
                                          |  .|     |. |.| |.| ||||.| . .   . .|..|. ||| . .|       
..........................................vvekg.....rvngglavsrafGdhflkknk..klkepyitaepdvkvvtl.......

dednrDGDYGVLVMATDGLWDVSENDAVSRTVFQTLSKYstEKHRYTMVAQELVARARGKindsghwrladskaAATVDDISVIVI
     . .  .|..|.|||||| .|. |  .| ..|.|   ...... .|..|.. |. .                  |.|.|.|.
.....tsedeflilaSDGlwdvlsnqevvdivrkllakg..ktndpqeaaelldeeairr..............ggseDniTvvvv
subfamily_PP2D1_pd Subfamily PP2D1 130-165 1.1e-06 20.6 In-house 29-64 (492) alignment 
Range on Protein: 130-165
Range on HMM: 29-64/492.0
PDLPYTYFGIFDGHAGYGAALAASHQFHHILHEKLV
.| .  .|||.||. |  ||  |....|..| |.| 
ndvnscFfgiyDGynGataAeiaakelhevlleele
subfamily_PPM1G2_pd Subfamily PPM1G2 131-264 1.3e-17 56.7 In-house 49-145 (287) alignment 
Range on Protein: 131-264
Range on HMM: 49-145/287.0
DLPYTYFGIFDGHAGYGAALAASHQFHHILHEklvdclelllprdadatngggegnklnptfphpiyfqRRVTKDELIIGALESAFFNMDSLIAQDCDRY
|   ..|..|||| |  .|  |..........                                     ..  |.. .  .|. || ..|. . .|    
dkslalfavfDGhGGakvakyagkklikkiak.....................................kksfkegaleqilkdafletDeellkdeklk

RDAGGCTACVSLFIDGKMYVANAGDSRAVLCQRR
 .  |.|| | | .. |.||||||||||||... 
desaGstavvvlikeeklyvanaGDsravlsskg
subfamily_PPM1A_pd Subfamily PPM1A 134-264 1.8e-15 50.1 In-house 42-145 (282) alignment 
Range on Protein: 134-264
Range on HMM: 42-145/282.0
YTYFGIFDGHAGYGAALAASHQFHHILHEklvdclelllprdadatngggegnklN----PtfphpiyFQRRVTKDELIIGALESAFFNMDSLIAQDCDR
 ..| .||||||  .|  ....... . |                          .             . . .... .  ||...|...|. | .. ..
wsfFavfDGHaGsevakyvkkhllenile..........................eeelke.......aaleasekdevkealrqgfLaldeairelstd

YR--DAGGCTACVSLFIDGKMYVANAGDSRAVLCQRR
..  |  |.|| . |  . ....||.||||||||. .
lktadksGsTavtvlvsekhliianlGDsRavlcrng
subfamily_PPM1L_pd Subfamily PPM1L 134-264 9.7e-11 34.4 In-house 35-136 (269) alignment 
Range on Protein: 134-264
Range on HMM: 35-136/269.0
YTYFGIFDGHAGYGAALAASHQFHHILHEKLVDClelllprdadatngggEGNKLNPTFphpiyfqrrVTKDELiigaLESAFFNMDSLIAQDCDRYRDA
 ..|..|||| |  ||  | . . . ...||..                 . .| | .          .. ..|    |.   . .|  . .   |  | 
esffavfdGhGGefaaefakdvlvkaiknkliel................dadkentep.........infskl....ltdeilsvdekllekakraedi

GGCTACVSLFIDGKMYVANAGDSRAVLCQRR
 |.|| ..|  . .. ||| |||| ||...|
aGttalialvqesdlivanvGdsrGvlydkr
subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 135-172 4e-06 18.9 In-house 34-70 (276) alignment 
Range on Protein: 135-172
Range on HMM: 34-70/276.0
TYFGIFDGHAGYGAALAASHQFHHILhEKLVDCLELLL
. |..|||||| ||| ||.. | ..| |||..  .  |
alfavfdGhaGkGaadaakklfpkel.ekllksgnysl
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 135-164 9.8e-06 18.0 In-house 37-66 (255) alignment 
Range on Protein: 135-164
Range on HMM: 37-66/255.0
TYFGIFDGHAGYGAALAASHQFHHILHEKL
 |. .||||.|  || .||.....|| |.|
dyyalfdGhgGraaakfaseelykilaell
PPM_PTC7_SpoIIE 136-463 2.1e-17 56.7 In-house 36-213 (230) alignment 
Range on Protein: 136-463
Range on HMM: 36-213/230.0
YFGIFDGHAGYGaaLAASHQFHHILHEKLVDCLElllprdadatngggegnklnptfphpiyfqrrvtKDELIIGALESAF-FNMDSLiaqdcdryRDAG
..|..||| |     .|. ... .|.|     ||                                  | | |...|. |.  ....          . .
vvgdvdGhGgra..alamgllrtalrelafagle..................................kpeeilrrlnlalaadlede........psss

GCTACVSLFIDGK--MYVANAGDSRAVLCQRRATperpqtntdsgiepdpleascypvpfsadhtpetererllnvarlkphlmgkhyvameyakrphik
|.||.| |.   .  .||||||||...|..  ..                                                                  
gaTavvalidpstgklyvanaGdsppllvrddgg..................................................................

dmgqrilcrqgtmrgwtykTLTMEDLCMPV-V---NGegkrsRLLGTLGVTRGFGDHELLAintgiqikpfltphpdvrqrdlT--QVVSIPDeDNRDGD
                   . .  ..  .. .   .|     |  |.| |.. .||  ||.                      |   | . || . ....
...................ererivagglpslGilpg.....rvfgvlavslapGdlllly......................tDGvveaepd.tsdgel

YG---VLVMATDGLWDVSENDAVSRTVFQTLSKYstekhR
.|    |..|.|||||| ... ....| ..|.|.      
fgkdeflilasdglwdvlspqelvdlvrdelekp.....a
subfamily_PDP_pd Subfamily PDP 136-266 5.3e-08 25.4 In-house 27-184 (398) alignment 
Range on Protein: 136-266
Range on HMM: 27-184/398.0
YFGIFDGHAGYGAALAASHQFHHILHEKLVDCLEL-----LLPRDA---------DATNGGGEGNKLNPTFPHP-IYFQRRVT-KDELIIGALESAFFNM
 ||.||||.|. .| | |..  . .  .|..  .|      |. ..         . ...    .. . .. .   |.|. .  . | .  ||..|| ..
lfgvfDGHggaacaeavskrLlkyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslselskylqelleaevekvkealkkaFlkl

DSLIAQDCD------RYRD-----AGGCTACVSLFIDGKMYVANAGDSRAVLCQRRAT
|. |...          |.     . | .|...|  . ...|||.||.||||.... .
DkdistealkklkekslreallvalsGacallaliegtelhvAntGDcravlgvqeee
subfamily_KAPP-like_pd Subfamily KAPP-like 136-262 1.8e-07 23.5 In-house 36-132 (266) alignment 
Range on Protein: 136-262
Range on HMM: 36-132/266.0
YFGIFDGHAGYGAALAASHQFHHILHEKLVDclelllprdadatngggegnKLNPTFPHPIYFQRRVtkdeliigaLESAFFNMDSLIAQdcdryRDAGG
 |..|||||| ||| ||.. | ..|...|                        .    ..|| |...         || || ..|. . .      .  |
lfavfdGhaGkGaadaakklfpkelekllks....................tkqddGGdniydqskl.........lenafkevdaklkd.....feyeG

CTACVSLF-IDGK---MYVANAGDSRAVLCQ
.|| ..|   ||.   . ||| ||| | |..
atatlalvwsdGqqrylqvanvGdssaflsr
PPM_PTC7 198-304 2e-15 49.9 In-house 62-149 (259) alignment 
Range on Protein: 198-304
Range on HMM: 62-149/259.0
FQRRVTKDELIIGALESAFFN--MDSLIAQDCDR-YRDAGGCTACVSLFIDGKMYVANAGDSRAVLCQRRATPerpqtntdsgiepdpleascypVPFSA
 ... ...|. . ||  .| .  .|. . .. ..   . .|.|| | |... |.||||.||||||||... .                       .... 
erksfeeleklekalrksflaldtdeelksseantepstsGstAvvalitgsklyvAnvGDSravLcrsgnav......................kqlte

DHTPETERER
||.|. |.||
dHkpsnedEr
PP2C Protein phosphatase 2C 199-304 1.9e-14 46.9 Pfam-A 63-148 (255) alignment 
Range on Protein: 199-304
Range on HMM: 63-148/255.0
QRRVTKDELIIGALESAFFN-MDSLIAQDCDR-YRDAGGCTACVSLFIDGKMYVANAGDSRAVLCQRRATPerpqtntdsgiepdpleascypVPFSADH
|.  ...|.   || ..| . .|. .... ..   .  |.|| |.|. . |.||||.||||||||... .                       . .. ||
qksflelekvekalrksfladtdeelksskantepsksGstavvalirgkklyvAnvGDSravLcrkdnak......................keltedH

TPETERER
.|. |.||
kpsdedEr
PP2C Protein phosphatase 2C 199-304 1.9e-14 46.9 In-house 63-148 (255) alignment 
Range on Protein: 199-304
Range on HMM: 63-148/255.0
QRRVTKDELIIGALESAFFN-MDSLIAQDCDR-YRDAGGCTACVSLFIDGKMYVANAGDSRAVLCQRRATPerpqtntdsgiepdpleascypVPFSADH
|.  ...|.   || ..| . .|. .... ..   .  |.|| |.|. . |.||||.||||||||... .                       . .. ||
qksflelekvekalrksfladtdeelksskantepsksGstavvalirgkklyvAnvGDSravLcrkdnak......................keltedH

TPETERER
.|. |.||
kpsdedEr
subfamily_PPM1E_pd Subfamily PPM1E 200-264 1.6e-07 23.8 In-house 70-132 (265) alignment 
Range on Protein: 200-264
Range on HMM: 70-132/265.0
RRVTKDELiiGALESAFFNMDSLIAQDCDRYRDAGGCTACVSLFIDGKMYVANAGDSRAVLCQRR
 ....| .   ||..|| ..|. . | . | .  .|.|| | |    ..|||  |||.|.|.. .
eklkedpa..ealkeafkltDerflqkaereklksGstavvvliekdqlyvaWlGDsqallvrkg
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 213-269 1.9e-09 30.2 In-house 78-130 (255) alignment 
Range on Protein: 213-269
Range on HMM: 78-130/255.0
ESAFFNMDSLIaqdcDRYRDAGGCTACVSLFIDGKMYVANAGDSRAVLCQRRATPER
. |. ... .|    . .    |.|| . |.|. |.|.|| ||||.||||. .| .|
kkaykeistqi....serpkfiGttaasvliiedkvyianvGdsrvvlcqkdgtakr
subfamily_PPM1K_pd Subfamily PPM1K 227-263 5.7e-07 21.9 In-house 91-128 (263) alignment 
Range on Protein: 227-263
Range on HMM: 91-128/263.0
CDRYRDAGGCTACVSLFIDGK-MYVANAGDSRAVLCQR
 ..   . | || |||. ||. . .|. |||||.||..
aeaellssGttatvsllrdGtelvlaslGdsrailcrn
subfamily_PPM1G_pd Subfamily PPM1G 233-304 5.1e-11 35.2 In-house 295-343 (473) alignment 
Range on Protein: 233-304
Range on HMM: 295-343/473.0
AGGCTACVSLFIDGKMYVANAGDSRAVLCQRratperpqtntdsgiepdpleasCYPVPFSADHTPETERER
  |.||.| |  . |..||||||||.||..                           . .| || || | |.
dsGttAvvaLlkekklivAnaGDsRcvlsrn.......................GkAldlslDHkPeDevEl
subfamily_TAB1_pd Subfamily TAB1 233-275 4.8e-09 28.4 In-house 128-170 (333) alignment 
Range on Protein: 233-275
Range on HMM: 128-170/333.0
AGGCTACVSLFIDGKMYVANAGDSRAVLCQRRATPERPQTNTD
.|| || | | .  |.||||.|||||.|..|. . .  | ..|
sgGttAvvalifnnkLyVaNvGdsrAllvkrkesekvkqLsvd
subfamily_ILKAP_pd Subfamily ILKAP 234-304 1.9e-09 30.1 In-house 113-166 (293) alignment 
Range on Protein: 234-304
Range on HMM: 113-166/293.0
GGCTACVSLFIDGKMYVANAGDSRAVLCQRRATPERpqtntdsgiepdpleasCYPVPFSADHTPETERER
 |.|| | | .|  .|||| |||.|||...   ...                    |... |||| .. ||
dGstatvvlvldnvlyvanlGdskavlvrkkeegdk.................iasvvLtkdhtpvkyeer
subfamily_PP2D1_pd Subfamily PP2D1 362-554 4.2e-07 22.0 In-house 232-408 (492) alignment 
Range on Protein: 362-554
Range on HMM: 232-408/492.0
VVNGEGKRSRLLGTLGVTRGFGDHELLAINTGIQIKPfltphpDvrqrdlTQVVSIPDEDNrdgdygVLVMATDGLWDVSENDAVSRTVFQTLSKYSTEK
||  ..| ..  | |..||| | .  . ..  . ..|             |. | . ...       .||.|. |||.| ... |   | |||  |  . 
vvvkseknglvnGildttRGLGnyGdpkLkksvipeP......k......ttsvkldeaaq......flvlAsnGlWevlseeevlsLvkqtlaiyksrv

HRYTMVAQELVARARGKINDSGHWRLADSKAAATVDDI--SVIVIPVCQYYKEHVEWTQNYKRDLEHRRRQAQAHMAQEAVNVLNGVIAEEAHVV
..  .   .. . .     ..   .|. . . .. | .  |.| . . .  . ..     |..  | ..   . . ...  |  . .. .| .. 
raenvpdsdvttvgedylgEleakklsaryentgfdkfvtseidldaaegdesnlqklfsynelsevkedaddereglseanskkeityneedtd
PPM_PTC7 366-475 2e-10 33.5 In-house 162-250 (259) alignment 
Range on Protein: 366-475
Range on HMM: 162-250/259.0
EgKRSRLLGTLGVTRGFGDHELLAINTgiqikpfltphpdvrqrDLTQVVSIPDEDNRDGDYG--VLVMATDGLWDVSENDAVSRTVFQTLSKYstekhR
. ...|. |.| |.| |||.||    |                 . ..|.. ||   .. |.    |..|.|||||| ... .   | ..|||       
v.gngrvngvlavsRafGdfelkpket.................eeqlvsaePdisstkideedefliLasdGlwdvvsdqeavdlvrselskk.....d

YTMVAQELVARA
 ...|..||  |
pmeaaeklvdea
subfamily_PPM1A_pd Subfamily PPM1A 368-475 2.8e-09 29.7 In-house 173-264 (282) alignment 
Range on Protein: 368-475
Range on HMM: 173-264/282.0
KRSRLLGTLGVTRGFGDHELLAINTGIQIKPFLTPHPDVRQRDLTqvvsipDEDnrdgDygVLVMATDGLWDVSENDAVSRTVFQTLSKYstekHRYTMV
  ||. |.| |.| .||.|.   ..  . .  ....|.|.  . .      .||    |   ||.| ||.||| ... |   | ..|..     .  ..|
vvsRvnGaLAvsRalGDyeykeeeekkaeeqlvsaepevtsiers......eed....d..flvlacDGiwDvlsdeevvelvrkrleva....deleev

AQELVARA
|..|| .|
akalvdka
subfamily_PPM1G2_pd Subfamily PPM1G2 368-475 2e-06 19.9 In-house 173-264 (287) alignment 
Range on Protein: 368-475
Range on HMM: 173-264/287.0
KRSRLLGTLGVTRGFGDHELLAINTgiqikpfltphpdvRQRDLTQVVSIPD--EDNRDGDYGVLVMATDGLWDVSENDAVSRTVFQTLSKYstekHRYT
.  |  |.| . | .||.|    ..               . .  .|  .||   ...| |   ||.| ||.||| .|. |   | . |..     ..  
elnrvngnLalsralgDfefkknvk..............kkpeeqivtavPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsg....akld

MVAQELVARA
 ...||. ..
eiieelldkc
PP2C Protein phosphatase 2C 369-475 1.8e-11 37.1 Pfam-A 161-246 (255) alignment 
Range on Protein: 369-475
Range on HMM: 161-246/255.0
RSRLLGTLGVTRGFGDHELLAINtgiqiKPFLTPHPDVRqrdltqvvsipdEDNRDGDYGVLVMATDGLWDVSENDAVSRTVFQTLSKYStekhRYTMVA
  |. |.| |.| .||.||   .     ... ...|||.            . ... .   |..|.|||||| ... .   | ..||| .      ...|
ngrvngsLavsRalGdfelkpke.....eqlvsaePdvt............svklteedefliLasdGlwdvlsdqeavdlvrselskkk....spmeaa

QELVARA
.|||  |
eelvdea
PP2C Protein phosphatase 2C 369-475 1.8e-11 37.1 In-house 161-246 (255) alignment 
Range on Protein: 369-475
Range on HMM: 161-246/255.0
RSRLLGTLGVTRGFGDHELLAINtgiqiKPFLTPHPDVRqrdltqvvsipdEDNRDGDYGVLVMATDGLWDVSENDAVSRTVFQTLSKYStekhRYTMVA
  |. |.| |.| .||.||   .     ... ...|||.            . ... .   |..|.|||||| ... .   | ..||| .      ...|
ngrvngsLavsRalGdfelkpke.....eqlvsaePdvt............svklteedefliLasdGlwdvlsdqeavdlvrselskkk....spmeaa

QELVARA
.|||  |
eelvdea
subfamily_PDP_pd Subfamily PDP 369-470 5.4e-07 22.0 In-house 222-327 (398) alignment 
Range on Protein: 369-470
Range on HMM: 222-327/398.0
RSRLLGTLGVTRGFGDHELLAINTgIQIKPFLT---PHPDVR----QRDLTQVVSIPDEDNRDGDyGVLVMATDGLWDVSENDAVSRTVFQTLSKYStEK
..||||.|  .| ||| ..   .  .| |.. .   ..  ..       ||    .     |  |   ||.|||||||. .|..| ..| . |.|   ||
ngRlLgeLqPlRAFGdvryKwsee.lqkkvlekaylkvlepkdyktPPYltaePevtshklrend.kFLvlatDGLwdllsneevvslVgehlakkk.ek

HRYTMVAQE
. ...  ..
epvkveeak
subfamily_PPM1E_pd Subfamily PPM1E 371-477 6.9e-07 21.7 In-house 166-248 (265) alignment 
Range on Protein: 371-477
Range on HMM: 166-248/265.0
RLLGTLGVTRGFGDHELlaintgiqiKPFLTPHPDVRQRDLtqvvsipdednrDGDYGVLVMATDGLWDVSENDAVSRTVFQTLSKystEKHRYTMVAQE
|  |.| |.|  || .|         ||... ..|| . .|            ||.  .|..|.|||||| ... | ..| . |..   ... ...||..
RvnGvLsvsRaiGDvkl.........kpyvsgeadvaevel............dgseeylilacDGlwDvvneeevvklveeflad...gaedlsevakl

LVARARG
||. |. 
lveaake
PPM_PTC7_SpoIIE_motif 429-504 1.2e-06 22.1 In-house 14-78 (81) alignment 
Range on Protein: 429-504
Range on HMM: 14-78/81.0
VLVMATDGLWDVSeNDAVSR----TVFQTLSKYstEKHRYTMVAQELVARARGkindsghwrladSKAAATVDDISVIVI
||...||||..   ..        .. .....   |...   .|..||....               .. . |||...|.
vllLyTDGltEar.dsdgelfgkeellrladra..egkslqeladklvdevle............ngsgereDDitllvl
PPM_PTC7_motif 431-476 4.2e-06 20.2 In-house 1-43 (51) alignment 
Range on Protein: 431-476
Range on HMM: 1-43/51.0
VMATDGLWDVSENDAVSRTVFQTLS-KYStekhRYTMVAQELVARAR
..|.|||||| ... .   | ..|| |.     .....|..|| .|.
iLAsDGLWDvlsdqeavdlvrdqlskkgl....spqeaAeklvdeal
MAS20 MAS20 protein import receptor 501-570 4.5e-06 13.1 Pfam-A 8-80 (121) alignment 
Range on Protein: 501-570
Range on HMM: 8-80/121.0
VIVIPVCQYYKEHVEWTQNYKRDLEHRRRQAQAH---MAQEAVNVLNGVIAEEAHVVEEEEEGEVVVHEARTS
....  | |. ..     .||. |..|||.....    .....  |.   | .....|| . || ........
alflgYCiYfDrkrrsdPdykkklrerRrkekkkkekaeasklpdlkdeeavqkffleeiqlGeellaqgdle
DUF2294 Uncharacterized conserved protein (DUF2294) 517-592 5.3e-06 12.6 Pfam-A 17-92 (118) alignment 
Range on Protein: 517-592
Range on HMM: 17-92/118.0
TQNYKRDLEHRRRQAQAHMAQ-EAVNVLNGVIAEEAHVVEEEEEGEVVVHEARTSHNQTKvPRRLDGTLDETLVVEL
.. .|  |...  ...... .  .. .|.||. ..   . |..||. .|...|..  ..   ..|.  . |.| |..
qklekellGrgpeeiktdivddmvivrlegvlTpaEkflaetkegrelvkqvRseLvesi.kekleelieeilgvkv