Gene CG15035 in Drosophila melanogaster

Synonym: Dmel\CG15035, Dmel_CG15035, CG15035

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PTC7
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP137_AA protein Get Run
DmelP137_AA_126-373 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0034914 PP2C-like 127-371 1.2e-28 92.9 In-house 30-288 (295) alignment 
Range on Protein: 127-371
Range on HMM: 30-288/295.0
NRGKFGEDAWFMSS-----SPQACIMGVADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNRPEILLERAYFDL--------LDQKCPIVGSCTAC
.| |  |||...        .. ...||.||.||..   |    .  .|.. .|..    .. .. .|  |..|.  .        |...  .....||.
GrrksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallrpelagsGtTav

ILALkrDDSTLYAANIGDSGFLVVRSGKVVCRSQEQQHQFNTPYQLASPPPGYDFD-----------------------------AVSDGPESAdTIQFP
.. .   ...|| ||.||| ....|.|..|. . .. . ... ..    . |. ..                             .||  |.   .... 
vali..rgnklyvanvGDSravllrngelvqltvdhkpvnelererilsaggavshgrvngvlavtRalGdfdlklllslllleplvsaePdvt.vlelt

MQLGDVILLATDGVYDNVPESFLVEVLTEMSGisNPVRLQMAANTVALMARTlsfspkhdspfsqnarkhdidawGGKPDDITVLLA
.. .|..|||.||..|..... .|......    .   |..||. .. .|                         .|. |.|||...
ledddfllLasDGlwdvlsneeivdivrslla..kgldleeaaeeLvdlAla.......................rgsrDNiTvvvv
PP2C_2 Protein phosphatase 2C 127-315 3.1e-10 32.7 Pfam-A 7-195 (212) alignment 
Range on Protein: 127-315
Range on HMM: 7-195/212.0
NRGKFGEDAWFMSSSPQACIMGVADGVGGWRnYGVDPGKFSMTLMRSCERMSHAPDFKPN---RPEILLERAY------FDLLDQKCPIVGSCTACILAL
..||. .||...... .. .. ||||.|  . ..    ..  . . .. . ... . ...     . ......      .    |....    |...||.
rkgkpcqDalaireasdgwllaVADGaGsak.rSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllav

kRDDSTLYAANIGDSGFLVV-RSGKVVCRSQEQQHQF-NTPYQLASPPPGYDFdavsdgpesaDTIQFPMQLGDVILLATDGVYDNVP-ESFLVEVLTEM
 ... ......|||.. .|. |.|.| . ........ |. . | |. .. ..          ........ || .|| |||| |..  |  . |.|.|.
.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeel..........rirrlklepgdalllmTDGvsdslrkeepfrellael

S
 
l
PP2C_2 Protein phosphatase 2C 127-315 3.1e-10 32.7 In-house 7-195 (212) alignment 
Range on Protein: 127-315
Range on HMM: 7-195/212.0
NRGKFGEDAWFMSSSPQACIMGVADGVGGWRnYGVDPGKFSMTLMRSCERMSHAPDFKPN---RPEILLERAY------FDLLDQKCPIVGSCTACILAL
..||. .||...... .. .. ||||.|  . ..    ..  . . .. . ... . ...     . ......      .    |....    |...||.
rkgkpcqDalaireasdgwllaVADGaGsak.rSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllav

kRDDSTLYAANIGDSGFLVV-RSGKVVCRSQEQQHQF-NTPYQLASPPPGYDFdavsdgpesaDTIQFPMQLGDVILLATDGVYDNVP-ESFLVEVLTEM
 ... ......|||.. .|. |.|.| . ........ |. . | |. .. ..          ........ || .|| |||| |..  |  . |.|.|.
.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeel..........rirrlklepgdalllmTDGvsdslrkeepfrellael

S
 
l
subfamily_PPTC7_pd Subfamily PPTC7 128-373 1.1e-108 355.4 In-house 7-251 (252) alignment 
Range on Protein: 128-373
Range on HMM: 7-251/252.0
RGKFGEDAWFMSSSPQACIMGVADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNRPEILLERAYFDLLDQKCPIVGSCTACILALKRDDSTLYAA
| |.||||.|.||. .|...||||||||||..|.||..||..||..||..|.........|. |||.|| .||..|.|..||.||||..|...|..|..|
rqkageDayfvsseksadvlgvADGVggWrsvGiDpsefsreLmkaceklskeskaeelkPvelleaayqelleekvpvlGssTacivvldksdkklesa

NIGDSGFLVVRSGKVVCRSQEQQHQFNTPYQLASPPPGYDFDAVSDGPESADTIQFPMQLGDVILLATDGVYDNVPESFLVEVLTEMSgISNPVRLQMAA
|.|||||||||.||||.||.||||.|||||||. .|.|.. ....| ||.||. .|... ||.|.|||||..||..|. ..|.|.|..  |.. .||..|
nlGDSgflvvRkgkvvfrskeqqhkfntPyQLsiapegregkvildkpeaadsksfavkkgDiivlatDGlfDNlledeileilkelk.eseksslqsla

NTVALMARTLSFSPKHDSPFSQNARKHDIDAWGGKPDDITVLLASV
...| .||.||..|...|||.|.|.|....|.|||||||||..|.|
kklaekarelsldpeyespfaqkakkngleasGGKpDDitvvvavv
0049733 PP2C-like 128-371 3e-33 108.2 In-house 13-231 (235) alignment 
Range on Protein: 128-371
Range on HMM: 13-231/235.0
R-GKFGEDAWFMssspQACIMGVADGVGGWRNYGVDPGKFSMTLMRSCERmshapdFKPNRPEILLERAYFDL--------LDQKCPIVGSCTACILALK
|  | .|||...    .  ...||||.||..  .|  . .  ||.. ...      . .  .| .|..|.  .        |...   .. .||... | 
rvrkvneDavlv....glllfavaDGhgghaagevasellvetllellle......lllldleealrkaflaaneallelalaspelagmgtTavvalld

rdDSTLYAANIGDSGFLVVRSGKVVCRSQEQQHQFNTPYQLASPPPGYD--------FDAVSDGPESADTIQFPMQLGDVILLATDGVYDNVPESFLVEV
  ...|| ||.||| ....|.||.|........ .....|    . |.           |. | . ..|. ..... ||..|||.||..|..... .|..
..ggklyvanvGDsrayllrdgklvqltedhspvnelerqriitaggavrvpgrlaltralGdlllkpdvtvlelepgdflllasDGlwdvlsdeeivdl

LTEmsgisnpVRLQMAANTVALMARTlsfspkhdspfsqnarkhdidawGGKPDDITVLLA
|..         |..||.... .|..                       .|..|.|||...
lrs.......ldleeaaerlvelala.......................rggrDNiTvvvv
PP2C_SIG_SM00331 129-372 2.2e-16 53.1 In-house 13-216 (217) alignment 
Range on Protein: 129-372
Range on HMM: 13-216/217.0
GK-FGEDAWFMSSSPQ-ACIMGVADGVGgwrnYGVDPGKFSMTLMRSCERMSHAPdfkpNRPEILLERAYFDLLDQKCPIVGSCTACILALKRDDSTLYA
.. ...|  .. . ..   .. ||||.|     |.. . .|  |    . ....     . .. .|.|.   . ..|    . .|.... ..  ...|. 
atqvsGDyydvvklnegrlllvvaDgmG....kGlaAaaassqlrtalrellseg....eelsqalkrlnraiyeekeekgmfaTlllalydfssgklsy

ANIGDSGFLVVRSGKVVCRSQEqqhqfNTPYQLASPPPGYdfdavsdgpesADTIQFPMQLGDVILLATDGVYDNVPES-----FLVEVLTEMSgisNPV
||.||| ....|.|| | . ..     .....|   |              .|. .. .. ||..||.|||. ... |       | |.|..     .  
anaGdsrpyllrdgklveilkd.....vegaplGlepevs...........vdirelelekgdllllytDGltearsekgfaeerleeiledlv...dse

RLQMAANTVALMARTLSFSPKhdspfsqnarkhdidawggkPDDITVLLAS
  ..|...|. . ...  |..                    .|||||..  
aqelaqkiveellelakgsng....................eDdiTvvvvk
PPM_PTC7_SpoIIE 135-304 1.2e-15 51.0 In-house 23-172 (230) alignment 
Range on Protein: 135-304
Range on HMM: 23-172/230.0
AWFMSSSPQACIMGVADGVGgwrnYGVDPgKFSMTLMR-SCERMShAPDFKpnRPEILLERAYFDL---LDQKcPIVGSCTACILALKRDDSTLYAANIG
|....||..     |.|..|     |..  .. |.|.|   ....  ...    || .|.|..  |   |. . |... .||... .  ....|| || |
ansekssggrlalvvgdvdG....hGgra.alamgllrtalrela.fagle..kpeeilrrlnlalaadlede.psssgaTavvalidpstgklyvanaG

DSGFLVVRSG-KvvcrsqeqqhqfnT---------PYqLASPPPgydfdavsdgpESADTIQFPMQLGDVILLATDGVYDNVPE
|| .|.||.. .             .         |. |.  |              ... ..... ||..||.|||| .. |.
dsppllvrddgg.............ererivagglps.lGilpg...........rvfgvlavslapGdllllytDGvveaepd
SpoIIE Stage II sporulation protein E (SpoIIE) 145-373 1.6e-13 42.9 Pfam-A 5-192 (193) alignment 
Range on Protein: 145-373
Range on HMM: 5-192/193.0
CIMGVADGVGgwrnYGVDPGKFSMTLMRSCERMShAPDFKpnrPEILLERAYFDL---LDQKcpiVGSCTACILALKRDDSTLYAANIGDSGFLVVRSGK
  ..|.|.||     |..   ... |    .... . . .   |. .|||..  |   |...   .  .||... .  .. .|. ||.|.. .|.||. .
lalvvgDvvG....hGleAalimgllrsalrela.tagle...paevlerlnealarnleee...erfatavlaeydpstgkleyanaGhpppllvrpdg

vvcRSQEQQHQFNTPyqLASPPPgydfdavsdgpESADTIQFPMQLGDVILLATDGVYDNV-PESFLVEVLTEMSGISNPVRLQMAANTVALMARTLSfs
   . ... .... |  |   |            . ... ..... ||..||.||||...  |.. | .    .. ...  . ....   ||....|.  
...gtkfllvstglp..lGilpe...........adyeeaelqlepgdllllyTDGvtEardpdgelfgkerllallaeaegesleelldalveelle..

pkhdspfsqnarkhdidaW--GGKPDDITVLLASV
                     |.. ||||.|.. |
..................lgsgeleDDitllvlrv
SpoIIE Stage II sporulation protein E (SpoIIE) 145-373 1.6e-13 42.9 In-house 5-192 (193) alignment 
Range on Protein: 145-373
Range on HMM: 5-192/193.0
CIMGVADGVGgwrnYGVDPGKFSMTLMRSCERMShAPDFKpnrPEILLERAYFDL---LDQKcpiVGSCTACILALKRDDSTLYAANIGDSGFLVVRSGK
  ..|.|.||     |..   ... |    .... . . .   |. .|||..  |   |...   .  .||... .  .. .|. ||.|.. .|.||. .
lalvvgDvvG....hGleAalimgllrsalrela.tagle...paevlerlnealarnleee...erfatavlaeydpstgkleyanaGhpppllvrpdg

vvcRSQEQQHQFNTPyqLASPPPgydfdavsdgpESADTIQFPMQLGDVILLATDGVYDNV-PESFLVEVLTEMSGISNPVRLQMAANTVALMARTLSfs
   . ... .... |  |   |            . ... ..... ||..||.||||...  |.. | .    .. ...  . ....   ||....|.  
...gtkfllvstglp..lGilpe...........adyeeaelqlepgdllllyTDGvtEardpdgelfgkerllallaeaegesleelldalveelle..

pkhdspfsqnarkhdidaW--GGKPDDITVLLASV
                     |.. ||||.|.. |
..................lgsgeleDDitllvlrv
PPM_PTC7 203-251 1.8e-07 23.9 In-house 97-135 (259) alignment 
Range on Protein: 203-251
Range on HMM: 97-135/259.0
KCPIVGSCTACILALKRDdstLYAANIGDSGFLVVRSGKVVcrsqeqqH
..  .||.  ..|  . .   || ||.|||.....|||..|       .
epstsGstAvvalitgsk...lyvAnvGDSravLcrsgnav.......k
PPM_PTC7_SpoIIE_motif 278-373 6.5e-08 26.2 In-house 2-80 (81) alignment 
Range on Protein: 278-373
Range on HMM: 2-80/81.0
ADTIQFPMQLGDVILLATDGVYDNV-PESFLVEVLTEMSGIS--NPVRLQMAANTVALMARTlsfspkhdspfsqnarkhdidaW--GGKPDDITVLLAS
.|. .|... |||.||.|||....  ... |... . .. ..     .|| .| ..   ..                          |.. ||||.|.. 
ydeaefqLkpgdvllLyTDGltEardsdgelfgkeellrladraegkslqeladklvdevle......................ngsgereDDitllvlr

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