Gene PDP1 in Homo sapiens

Synonym: PDH, PDP, PDPC, PPM2C, PDP1

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PDPc
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP169_AA protein Get Run
HsapP169_AA_160-585 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PP2Cc_SM00332 161-582 2.7e-70 229.9 In-house 4-274 (274) alignment 
Range on Protein: 161-582
Range on HMM: 4-274/274.0
DGKNVSSILGFdSNQLPANAPIEDRRSAATCLQ--TRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLeienavesgrallpilqwhkhpndy
.|.| . . |. |.. ... ..||.    ..|.  ..... ||||||.| .... ||..|. ... .|  ... |                         
sgsnlglsygk.ssmqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel.........................

fskeasklyfnslrtywqelidlntgestDIDVKEALINAFKRLDNDISLEAQVGDPNSflnylvlrvAFSGATACVAHVDGVDLHVANTGDSRAMLGVQ
                             . ||.||| .||...|..|  |.|.  ..          | ||.||.||.... ||.|||.|||||.|. .
.............................eddveealkkaflstdeeileeeqskelen.........alsGstavvallkkedlyvanvGDSravlcrn

EEdgswsAVTLSNDHNAQNERELERLKLEHPkseaksVVKQDRLLGLLMPFRAFGDVKFKWSIdlqkrviesgpdqlndneytkfippnYHTPPYLTAEP
..     || ||.||....|.|..|.| ...      ||...|. | |.  |||||...|...                          ....||.||||
gk.....avqlsvdhkpedederkRikkagg......vvekgrvngglavsrafGdhflkknk..........................klkepyitaep

EVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMhhqqpiavggykvtlgqmhgllterrtkmsSVFEDQNAATHLIRHAVGNnefgtvdher
.|....|...|.||.||.||||. .. |.|| || . |. .                              .  . |.||..|...|  .          
dvkvvtltsedeflilaSDGlwdvlsnqevvdivrkllakg..............................ktndpqeaaelldeeairr..........

lskmlslpeelaRMYRDDITIIVV
            ....|.||..||
............ggseDniTvvvv
subfamily_PDP_pd Subfamily PDP 172-586 1.2e-174 574.1 In-house 1-398 (398) alignment 
Range on Protein: 172-586
Range on HMM: 1-398/398.0
DSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSL
|||||..|.|||||||.|..|...|.|.||||||.|.||..|||.||..|.|.|||....| |.|.|.|||.|||..|...||..|..|.||.||....|
dsnqLasNePiEDrrseakllesngvlfgvfDGHggaacaeavskrLlkyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslsel

RTYWQELIDLNTGestdiDVKEALINAFKRLDNDISLEAQVGDPNSFLNYlVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSN
..|.|||......     .||||| .||..||.||| ||.   ... |.. .|.||.|||.|..|...| .||||||||.||.||||||.|||.||.||.
skylqelleaeve.....kvkealkkaFlklDkdistealkklkekslre.allvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLsk

DHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESgpdqlndnEYTKFIPP-NYHTPPYLTAEPEVTYHRLRPQDK
|..|.||.|.||.| |||..|.|.|....|||| |.|.||||||..||| .|||.|.|.        .|.|...| .|.||||||||||||.|.||..||
dqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwseelqkkvlek........aylkvlepkdyktPPYltaePevtshklrendk

FLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSvfEDQNAATHLIRHAVGNNEFGtvDHERLSKMLSLPEELA
||||||||||.......||..|||.|.......|..|  .|.|| |..  |.||..|...  ||.||||||||||.|.||.|  |.|..|..||.|||||
FLvlatDGLwdllsneevvslVgehlakkkekepvkveeakltlkqvveelkerkrklkr..edknaAthLirhalggneag..dkekvsallsiPeela

RMYRDDITIIVVQFNS
||||||||..||.|||
RmyRDDitvtVvffns
0034914 PP2C-like 177-585 5.3e-56 182.6 In-house 31-291 (295) alignment 
Range on Protein: 177-585
Range on HMM: 31-291/295.0
PaNAPIEDRRSAATCL---QTRGMLLGVFDGHAGCACSQAVSERLFYYIAvsllphetlleI-----------Enavesgrallpilqwhkhpndyfske
  . . ||. .. ..|   .. ..|.|||||| |.|... .||.|.....                       .                          
r.rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelll...........ellekllllltls..........................

asklyfnslrtywqelidlntgestDIDVKEALINAFKRLDNDISLEAQVGdpnsflnylvLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGvqeEDG
                         . |..|||..||...|...  .|.             ..|.||.||.||.. |  |.|||.|||||.|     .|
.........................ledieealrkaflaadeellelallr..........pelagsGtTavvalirgnklyvanvGDSravll...rng

swSAVTLSNDHNAQNERELERLKLEHPkseaksVVKQDRLLGLLMPFRAFGDVKFKWSidlqkrviesgpdqlndneytkfiPPNYHTPPYLTAEPEVTY
   .| |..||.  || | ||.. ...      .|  .|..|.|.  ||.||. .|..                        .......|...|||.||.
..elvqltvdhkpvnelererilsagg......avshgrvngvlavtRalGdfdlkll........................lslllleplvsaePdvtv

HRLR-PQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHqqpiavggykvtlgqmhgllterrtkmssvfeDQNAATHLIRHAVGnnefgtvdherlsk
..|  ..|.||.||.||||...  ...|.|| ..|.. ..                                 ..||..|...|.               
leltledddfllLasDGlwdvlsneeivdivrsllakgld................................leeaaeeLvdlAla..............

mlslpeelaRMYRDDITIIVVQFN
         |..||.||..||..|
.........rgsrDNiTvvvvrln
subfamily_PPM1A_pd Subfamily PPM1A 178-432 9.9e-20 64.0 In-house 22-209 (282) alignment 
Range on Protein: 178-432
Range on HMM: 22-209/282.0
ANAPIEDRRSAATCLQTR--GMLLGVFDGHAGCACSQAVSERLFYYIAVsllphetlleienavesgrallpilqwhkhpndyfskeasklyfnslrtyW
  .  ||. .....|...  . .  |||||||  ... |.. |   |                                                     
wrvemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenile..................................................e

QELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDP--NSflnylvlrvafsGATACVAHVDGVDLHVANTGDSRAMLGVQEedgswSAVTLSNDH
.|| . .. .|.. .||||| ..| .||..|. . .  .   .|            |.|| .. |    | .|| |||||.|  ..     .|. |..||
eelkeaaleasekdevkealrqgfLaldeairelstdlktadks............GsTavtvlvsekhliianlGDsRavlcrng.....kaaflteDH

NAQNERELERLKlehpksEAKSVVKQDRLLGLLMPFRAFGDVKFKW--SIDLQKRVIESGP
 .....| .|..      .|   |  .|. | |   ||.|| ..|   . . ... . . |
kpsrpkEkkRie......qAGGsvvvsRvnGaLAvsRalGDyeykeeeekkaeeqlvsaep
0049733 PP2C-like 183-585 9.3e-34 109.9 In-house 19-234 (235) alignment 
Range on Protein: 183-585
Range on HMM: 19-234/235.0
EDRRSAatclqtRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPhE-TLLeienavesgrallpilqwhkhpndyfskeasklyfnslrtywqelidl
||.  .       ..|..|.||| |.|... .||.|. ...  ||.   .|                                                 
eDavlv......glllfavaDGhgghaagevasellvetllellle.lllld................................................

ntgestdidVKEALINAFKRLDNDISLEAQVGDpnsflnylvlRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVqeedgSWSAVTLSNDHNAQNEREL
         ..|||..||..... .  .|.              .| .|.||.|| .||  |.||| |||||.|       .  .| |. ||.  || | 
.........leealrkaflaaneallelalasp..........elagmgtTavvalldggklyvanvGDsrayllr.....dgklvqltedhspvneler

ERLKLEHPKSeaksvvkqdRLLGLLMPFRAFGDVKFKwsidlqkrviesgpdqlndneytkfippnyhtppyltaePEVTYHRLRPQDkFLVLATDGLWE
.|.. ...           | .| |.  ||.||  .|                                       |.||...|.|.| ||.||.||||.
qriitaggav.........rvpgrlaltralGdlllk.......................................pdvtvlelepgd.flllasDGlwd

TMHRQDVVRIVGEylTGMhhqqpiavggykvtlgqmhgllterrtkmssvfedQNAATHLIRHAVGnnefgtvdherlskmlslpeelaRMYRDDITIIV
 .  ...|... .  . .                                   ..|| .|...|.                        |  ||.||..|
vlsdeeivdllrs..ldl...................................eeaaerlvelala.......................rggrDNiTvvv

VQFN
|...
vrld
subfamily_PPM1L_pd Subfamily PPM1L 183-418 3.7e-12 39.1 In-house 20-188 (269) alignment 
Range on Protein: 183-418
Range on HMM: 20-188/269.0
EDRRSAATCL--QTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAvesgrallpilqwhkhpndyfskeasklyfnslrtywqelid
|||   .. .  .|   ...||||| |   .. . ..|   |   |.  ..  | .                                            
edrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentep..........................................

lntgestdidvkealINAFKRLDNDIsLEAQvgdpNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLgvqeEDGSWSAVTLSNDHNAQNERE
               ||  | | ..| | ..    . .|. .      .|.|| .| |.. || ||| |||| .|     | .  |. || ||  |. .|
...............infsklltdei.lsvd....ekllekakraediaGttalialvqesdlivanvGdsrGvl....ydkrGkaiplsfdhkpqqvke

LERLKLEHPkseAKSVVKQDRLLGLLMPFRAFGDVKFK
  |.|         .     |. |.|   ||.||  .|
rkrikkaGG...fiafrGvwrvaGvlatsralGdyplk
subfamily_PPM1H_pd Subfamily PPM1H 193-385 1.1e-10 33.8 In-house 59-214 (404) alignment 
Range on Protein: 193-385
Range on HMM: 59-214/404.0
QTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAvesgrallpilqwhkhPNDYFSKEASKLYFNSLRTYWqelidLNTGESTDIDVK
.   .. |.|||||| . . . |. |   .   |     ||  ..|                 .. . .| ||   .| .. .      .   |..  |.
klplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksa................eeeenteesskespssvseiy.....eekeiskeeLvi

EALINAFKRLDNDISLEAQVgdpnsflnYLvlrvAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDgswsaVTLSNDHNAQNERE-LERLK
 || .||...|. |. | .         |        | ||.|| |    |.||| |||||.|  ..|      . ||.|.  . ||. | .| 
GalesaflemDeqiarerea........yr....ikGGCtalvalvllgklYvanaGDsRailvrkdei.....iplsadftPeteRqRlqela
subfamily_PPM1G2_pd Subfamily PPM1G2 197-499 1.9e-28 92.2 In-house 53-250 (287) alignment 
Range on Protein: 197-499
Range on HMM: 53-250/287.0
MLLGVFDGHAGCACSQAVSERLFYYIAVsllphetlleienavesgrallpilqwhkhpndyfskeasklyfnslrtywqelidlnTGESTDIDVKEALI
 |..||||| | .... ....|  .||                                                             . ..  ....|.
alfavfDGhGGakvakyagkklikkiak..........................................................kksfkegaleqilk

NAFKRLDNDISLEaqvgdpnsflnyLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEdgswsAVTLSNDHNAQNERELERLKlehpksEAKSV
.||...|...  .              |.   .|.|| |. .   .| |||.|||||.| .. .     . .|| ||  |.| | .|..      .|  .
dafletDeellkd............eklkdesaGstavvvlikeeklyvanaGDsravlsskgn.....vkalsfDhkPqeesekkrii......aagGf

VKQDRLLGLLMPFRAFGDVKFKWSIDlqkrviesgpdqlndneytkfIPPNYHtppYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYL
|. .|  | |   ||.|| .|| .                       ..|. .     ||.|.|. ..|...| ||||| ||.|. .. ..|| .| | |
velnrvngnLalsralgDfefkknvk.....................kkpeeq...ivtavPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerl

TGM
.  
vsg
Rod_C Rough deal protein C-terminal region 217-301 1.8e-06 12.8 Pfam-A 12-95 (551) alignment 
Range on Protein: 217-301
Range on HMM: 12-95/551.0
RLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELidlNTGESTDIDVKE--ALINAFKR
|| . . .   |  ..|. | .||. . ||.. .  |  .|.. ..|.|  .. |.   .|    .  ||. .  ||  ..... ..
RlPFhlllteqplkkilseelsvenfktllllvklmkvslDklymsavknvikelkpkllek...kkkeswhlqskevnkvlqsils
PP2C_SIG_SM00331 260-503 2.6e-08 26.7 In-house 45-188 (217) alignment 
Range on Protein: 260-503
Range on HMM: 45-188/217.0
SKEASKLYFNSLRTYWQELidlntgestdidvkEALINAFKRLDNDISLEaqvgdpnsflnylvLRVAFSGATACVAHV--DGVDLHVANTGDSRAMLGV
. .||.   . ||....|               |.| .|.|||.  |  |                .  ..||...|..   .  |..|| ||||  |  
Aaaassqlrtalrellseg..............eelsqalkrlnraiyee..............keekgmfaTlllalydfssgklsyanaGdsrpyllr

qeEDGSWSAVTLsndhnaqnerelerlklehpkseaksvvkqdrllgllmpfrafgdvkfkwsidlqkrviesgpdqlndneytkfippnyHTPPYLTAE
  ...    ..                                                                                 ... |  |
..dgklveilkd...............................................................................vegaplGle

PEV----TYHRLRPqDKFLVLATDGLWETM-----HRQDVVRIVGEYLtGMHHQQ
|||    .   | . . .|.|.||||.| .      .... .|. ... ....|.
pevsvdirelelek.gdllllytDGltearsekgfaeerleeiledlv.dseaqe
PPM_PTC7 261-494 1.5e-37 122.5 In-house 46-232 (259) alignment 
Range on Protein: 261-494
Range on HMM: 46-232/259.0
KEASKLYFNSLRTYWQELIDLNTGEstdiDVKEALINAFKRLDNDISLEAqvgD-PNsflnylVlRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQE
 ||.|.  ..| . ..| ......|    ....||...| .|| |..|.    .  |            ||.|| || . | .|.|||.|||||.|. ..
reaakyarehleeilkerksfeele....klekalrksflaldtdeelks...sean......t.epstsGstAvvalitgsklyvAnvGDSravLcrsg

EDGswsaVTLSNDHNAQNERELERLKLEHPKSEAKsvvKQDRLLGLLMPFRAFGDVKFKWSIDlqkrviesgpdqlndneytkfippnyhTPPYLTAEPE
..     ..|..||...||.| ||.. .. . . .   .. |. | |   |||||...|                               ......|||.
nav....kqltedHkpsnedEreRiegaggsvsnv...gngrvngvlavsRafGdfelkpket...........................eeqlvsaePd

VTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGE
.. . . ..|.||.||.||||. .  |..| .| .
isstkideedefliLasdGlwdvvsdqeavdlvrs
PP2C Protein phosphatase 2C 261-500 2.2e-37 122.0 Pfam-A 46-233 (255) alignment 
Range on Protein: 261-500
Range on HMM: 46-233/255.0
KEASKLYFNSLRTYWQELIDLNTGEstdiDVKEALINAFKRlDNDISLEAqvgDP-NsflnylVlRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQE
 ||.|.  ..|.. ..| ......|    .|..||...| . | | .|.    .  |            ||.|| || . | .|.|||.|||||.|. . 
reaakyarehleeilkeqksflele....kvekalrksfla.dtdeelks...skan......t.epsksGstavvalirgkklyvAnvGDSravLcrkd

EDGswsaVTLSNDHNAQNERELERLKLEHPKSEAksvvkQDRLLGLLMPFRAFGDVKFKWSIdlqkrviesgpdqlndneytkfippnyhtPPYLTAEPE
..     ..|..|| ...|.| ||.. .. . .      . |. | |   ||.||...|                                ... .|||.
nak....keltedHkpsdedEreRIeeaggsvsn.....ngrvngsLavsRalGdfelkpke.............................eqlvsaePd

VTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMH
|| ..| ..|.||.||.||||. .  |..| .| . |. ..
vtsvklteedefliLasdGlwdvlsdqeavdlvrselskkk
PP2C Protein phosphatase 2C 261-500 2.2e-37 122.0 In-house 46-233 (255) alignment 
Range on Protein: 261-500
Range on HMM: 46-233/255.0
KEASKLYFNSLRTYWQELIDLNTGEstdiDVKEALINAFKRlDNDISLEAqvgDP-NsflnylVlRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQE
 ||.|.  ..|.. ..| ......|    .|..||...| . | | .|.    .  |            ||.|| || . | .|.|||.|||||.|. . 
reaakyarehleeilkeqksflele....kvekalrksfla.dtdeelks...skan......t.epsksGstavvalirgkklyvAnvGDSravLcrkd

EDGswsaVTLSNDHNAQNERELERLKLEHPKSEAksvvkQDRLLGLLMPFRAFGDVKFKWSIdlqkrviesgpdqlndneytkfippnyhtPPYLTAEPE
..     ..|..|| ...|.| ||.. .. . .      . |. | |   ||.||...|                                ... .|||.
nak....keltedHkpsdedEreRIeeaggsvsn.....ngrvngsLavsRalGdfelkpke.............................eqlvsaePd

VTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMH
|| ..| ..|.||.||.||||. .  |..| .| . |. ..
vtsvklteedefliLasdGlwdvlsdqeavdlvrselskkk
subfamily_KAPP-like_pd Subfamily KAPP-like 261-388 3.1e-06 19.4 In-house 50-158 (266) alignment 
Range on Protein: 261-388
Range on HMM: 50-158/266.0
KEASKLYFNSLRTYWQElIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFlnYLVLRVAfsgatacvahvDGVDLHVANTGDSRAMLGVQEE
. |.||. . |  . ..  . . |     | .. | |||| .|. ..     |   .    || .             .   | ||| ||| |.|   .|
daakklfpkelekllks.tkqddGGdniydqskllenafkevdaklkdfeyeGatatl..alvwsdG...........qqrylqvanvGdssaflsrGne

dgswsAVTLSNDHNAQNERELERLKLEH
     .. || ||.|....|  |.| . 
.....slelskdhkakdpeekqrikddG
PPM_PTC7_SpoIIE 270-492 1.5e-19 63.7 In-house 53-205 (230) alignment 
Range on Protein: 270-492
Range on HMM: 53-205/230.0
SLRTYWQELIdLNTGEstdiDVKEALINAFKRLDNDISLEaqvgdpnsflnylvlrVAFSGATACVAHVDGVD--LHVANTGDSRAMLGVQeEDGswsav
 ||| ..||.  ...|    ...|.|.... .|. |.  |                .. |||||.||..|. .  |.||| |||...|  . ..|     
llrtalrela.fagle....kpeeilrrlnlalaadlede................psssgaTavvalidpstgklyvanaGdsppllvrd.dgg.....

tlsndhnaqnerelERLKLeHPKSEAKsV-VKQDRLLGLLMPFRAFGDVKFKWsidlqkrviesgpdqlndneytkfippnyhTPPYLTAEPEvTYHRLR
              ||  .  .   .  . .  .|  | |   .|.||. ..                               |  . .|||. | . . 
..............ereri.vagglps.lGilpgrvfgvlavslapGdlllly..............................tDGvveaepd.tsdgel

PQ-DKFLVLATDGLWETMHRQDVVRIV
.. |.||.||.||||. .  |..|..|
fgkdeflilasdglwdvlspqelvdlv
subfamily_ILKAP_pd Subfamily ILKAP 285-419 8.1e-14 44.4 In-house 79-198 (293) alignment 
Range on Protein: 285-419
Range on HMM: 79-198/293.0
ESTDIDVKEALINAFKRLDNDISLEAQVGDPNsflnYlvlRvafSGATA-CVAHVDGVdLHVANTGDSRAMLGVQEEDGS-WSAVTLSNDHNAQNERELE
 ... ..| .|...||. |..   .|. . |     .   .    |.|| .|  .| | |.||| |||.|.|  ..|.|.  ..|.|. ||.. .. | .
sakekeikkclvdsfkktdeefLklaskakPv....W...k...dGstatvvlvldnv.lyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerk

RLKlehpksEAKSVVKQDRLLGLLMPFRAFGDVKFKW
|..       | .||...|.||.|   |. || .|| 
riq......kaGgvvrdgrvlGvlevsrsiGdgrfkr
subfamily_PPM1D_pd Subfamily PPM1D 286-385 1.4e-10 33.8 In-house 70-165 (309) alignment 
Range on Protein: 286-385
Range on HMM: 70-165/309.0
STDIDVKEALINAFKRLDNDISLEAQvgdpnSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEE-DGSWSAVTLSNDHNAQNERELERL
| . || ||. .||  . . .  . .     .. .     .. .|.|| |  . . .|.||. |||...|||.|. . .. | .| .||  .. .| ||.
sepedvleAireaflatheamkkkle.....eWpktksgllstaGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekeri

K
.
e
subfamily_PPM1K_pd Subfamily PPM1K 288-418 2.9e-13 42.5 In-house 64-182 (263) alignment 
Range on Protein: 288-418
Range on HMM: 64-182/263.0
DIDVKEALINAFKRLDNDISLEAQVGDPNSflnylvlRVAFSGATACVAHV-DGVDLHVANTGDSRAMLGVQeedGSwsAVTLSNDHNAQNERELERLKL
. |... | |||. ||....  ..   ...           ||.|| |. . ||..| .|..|||||.|  .   |   |  |..||. . | | ||.| 
ekdleivlknafeeldkklkrylefsvaea.......ellssGttatvsllrdGtelvlaslGdsrailcrn...Gk..akkltrdhdPeleeekerika

EHPKSEAKSVvKQDRLLGLLMPFRAFGDVKFK
   . | .|.  . .. | |   |..||...|
agGsvewnsl.gkplvngrlamtrslGdldlk
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 325-415 7.2e-08 25.0 In-house 91-175 (255) alignment 
Range on Protein: 325-415
Range on HMM: 91-175/255.0
RVAFSGATACVAHVDGVDLHVANTGDSRAMLGvqEEDGswSAVTLSNDHNAQNERELERLKLEhpKSEAKSVVKQDRLLGLLMPFRAFGDV
|  | |.|| .. . .    .|| ||||..|.  . ||   |. || ||. ..|.| .|..         | |.  |. | |   ||.||.
rpkfiGttaasvliiedkvyianvGdsrvvlc..qkdg..takrlsldhkPseeseekrisel..GGtvvstvvtsrvnGtlavsralGds
subfamily_PPM1E_pd Subfamily PPM1E 328-419 1.2e-07 24.2 In-house 101-184 (265) alignment 
Range on Protein: 328-419
Range on HMM: 101-184/265.0
FSGATACVAHVDGVDLHVANTGDSRAMLGVQEEdgswsAVTLSNDHNAQNERELERLklEHPKSeAKSVVKQDRLLGLLMPFRAFGDVKFKW
 ||.|| |. ...  |.||  |||.|.|  . |     ||.| . |. ..|.| .|.  |.       |. . |  | |   || |||| | 
ksGstavvvliekdqlyvaWlGDsqallvrkge.....avqlmkpHkPeredEkkRi..eeagG.lvvvigawRvnGvLsvsRaiGDvklkp
subfamily_PPM1G_pd Subfamily PPM1G 329-497 2.3e-22 72.6 In-house 296-430 (473) alignment 
Range on Protein: 329-497
Range on HMM: 296-430/473.0
SGATACVAHVDGVDLHVANTGDSRAMLGVQeedgsWSAVTLSNDHNAQNERELERLKlehpksEA-KSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRv
||.||.|| . . .| ||| ||||..|  .       |. || ||  ..| ||||..      .|   | .. |. | |   ||.||  .|   .|... 
sGttAvvaLlkekklivAnaGDsRcvlsrn.....GkAldlslDHkPeDevEleRie......kAGGkvdedgRvnGGLnlsRAlGDhaYkkneeLplk.

iesgpDQLndneytkfippnyhtppyLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLT
     .|.                  ..| |..  . | ..|.|||||.||.| .|. |.||  | . |.
.....eqm..................isAlPDikvltlteedeFlvlAcDGiWnvmesqevvdfvraklk
subfamily_TAB1_pd Subfamily TAB1 329-418 1.8e-14 46.3 In-house 129-213 (333) alignment 
Range on Protein: 329-418
Range on HMM: 129-213/333.0
SGATACVAHVDGVDLHVANTGDSRAMLGVQEEdgSWSAVTLSNDHNAQNERELERLKLEHPKSEaksVVKQDRLLGLLMPFRAFGDVKFK
 |.|| || .   .|.||| |||||.|  ..|  |   . || ||. .|| ||.|||      |    .|. ..||  .. |. || | |
gGttAvvalifnnkLyVaNvGdsrAllvkrke..sekvkqLsvdHttdNedEllRlkdLGldie...qikrnkrlgskentRsiGdykvk
subfamily_PPM1E_pd Subfamily PPM1E 450-500 8.5e-09 28.0 In-house 182-232 (265) alignment 
Range on Protein: 450-500
Range on HMM: 182-232/265.0
TPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMH
. ||...|..|.  .|  ....|.||.||||.......||..| |.|.  .
lkpyvsgeadvaeveldgseeylilacDGlwDvvneeevvklveefladga
subfamily_PPM1H_pd Subfamily PPM1H 450-502 1.7e-08 26.6 In-house 301-357 (404) alignment 
Range on Protein: 450-502
Range on HMM: 301-357/404.0
TPPYLTAEPEVTYHRLR----PQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQ
  |.|...|||.   |.     .|. |.|||||||. .  ..| .|| | |. ....
ikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvepe
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 451-493 3.3e-06 19.6 In-house 178-221 (255) alignment 
Range on Protein: 451-493
Range on HMM: 178-221/255.0
PPYLTAEPEVT-YHRLRPQDKFLVLATDGLWETMHRQDVVRIVG
 |.....|...   .   .||||.|| ||.|. .  .. | || 
ePfvvpdPdlsqsleiskkdkflilacdGiwdlisdeeaveiva
subfamily_PPM1A_pd Subfamily PPM1A 454-584 3e-09 29.6 In-house 205-280 (282) alignment 
Range on Protein: 454-584
Range on HMM: 205-280/282.0
LTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIavggykvtlgqmhgllterrtkmssvfedqnaathlirhavgnnefgt
..||||||  .   .|.||||| ||.|...  ..|| .| . |.  .. . .                                                
vsaepevtsierseeddflvlacDGiwDvlsdeevvelvrkrlevadeleev................................................

vdherlSKMLsLPEELARMYRDDITIIVVQF
      .| | . . | .  || ....|| |
......akal.vdkalekgsrDNlsvlvvlf
subfamily_ILKAP_pd Subfamily ILKAP 454-503 1.1e-07 24.3 In-house 201-250 (293) alignment 
Range on Protein: 454-503
Range on HMM: 201-250/293.0
LTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQ
... |.|.  .| . |.|.||| ||||.... ..||. . . |   ....
vistPdvkkceLtendlfvvlaCdGLwkvfsadevvkfilkvledeeddr
subfamily_PPM1D_pd Subfamily PPM1D 456-496 9.4e-08 24.5 In-house 224-265 (309) alignment 
Range on Protein: 456-496
Range on HMM: 224-265/309.0
AEPEVTYHRLRPQDK-FLVLATDGLWETMHRQDVVRIVGEYL
 ||.|. ..| |... |..||.||||. .  .|.|..| .. 
PePdvkvrtldpneekfiilasDGlwnvltpedavsvvekee
subfamily_PP2D1_pd Subfamily PP2D1 456-562 7e-07 21.3 In-house 266-371 (492) alignment 
Range on Protein: 456-562
Range on HMM: 266-371/492.0
AEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMH-HQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNaaTHLIRHAVGNNEFGTV
 ||..|   |  ...|||||. |||| .  ..|. .| . |. .. . .   | . .||    ..|     .|.|  .|..    . .  .. . . .  
pePkttsvkldeaaqflvlAsnGlWevlseeevlsLvkqtlaiyksrvraenvpdsdvttvgedylgEleakklsaryentg..fdkfvtseidldaaeg

DHERLSKM
|.  | |.
desnlqkl
Subfamily Dicty-PPM1L-like 466-503 4.8e-06 18.6 In-house 233-270 (305) alignment 
Range on Protein: 466-503
Range on HMM: 233-270/305.0
RPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQ
...|.||||||||||| .. ||||  | | |    .|.
kanDqflvlatdGlwevlsyqdvveevkellrdkssqk