Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0034914 | PP2C-like | 63-507 | 6.4e-56 | 182.3 | In-house | 6-290 (295) | alignment | ||
Range on Protein: 63-507
Range on HMM: 6-290/295.0
RPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVltvkkkagavtstpnrnsskrrsslpngeglqlkeNSESEGVSCHYWSLFDGHAGSGAAVVA
.|.| | .. |.. . .. . . |.. .|||. .. . | | ..... .|||| |. || ||
lpllellllsslllllrvgvasdqGrrksneDavlvvl...................................nllslledlllfgvfDGhgGhaaaeva
SRLLQHHITEQLQDIVDILKNSavlpptclgeepentpansrtltraaslrggvgapgspstpptrfftekkiphECLVIGALESAFKEMDLQIERERSS
|.|| ... |.|. .. .| .| . .. ||..||...| .. .. .
sellvelllellekllllltls.....................................................ledieealrkaflaadeellelall
--YNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTP--ETERQRLQYLAfmqphllgnefthlefprrvqrkelgkkmlyrdfnmtgw
. . .|.||.... .||||||.|||||...||||..... . .| |.||.|.. .
rpelagsGtTavvalirgnklyvanvGDSravllrngelvqltvdhkpvnelererilsag.......................................
ayktiededlkfpliyGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSkydHGSDDVLILATDGLWDVLSNEEVAEAITQFLPN
| ||. .. ||| |||.|||.. |.....|..|. |.|....|. ...||.|.||.|||||||||||... ....| .
................gavshgrvngvlavtRalGdfdlklllslllleplvsaePdvtvlelt...ledddfllLasDGlwdvlsneeivdivrsllak
CDPddphrYTLAAQDLVMRARGvlkdrgwrisndrLGSGDDISVYVIPL
... .. ||. || .| || |.|.| |. |
gld.....leeaaeeLvdlAla.............rgsrDNiTvvvvrl
|
|||||||||
subfamily_PPM1H_pd | Subfamily PPM1H | 67-508 | 1.2e-199 | 656.1 | In-house | 2-403 (404) | alignment | ||
Range on Protein: 67-508
Range on HMM: 2-403/404.0
ILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKK--AGAVTSTPnrnsskrrsslpngeglqlKENSESEGVSCHYWSLFDGHAGSGAAVVASR
...|.||||||.|||||||||||..|||||...||..||. . .|||.| ||.||.|.....|..|||||||||||.|||.
vprelrrlPwaaGYaevinagkselneDqaaakvlllkkekkeksvtskp...................kekseeeklplayfglfDGhaGsgaalvask
LLQHHITEQLQDIVDILKNSAVlpptclgEEPENTPANSrtltraaslrggvgaPGSPSTPPTRFfTEKKIPHECLVIGALESAFKEMDLQIERERSSYN
||..|..|.|.|....|.... ||.|||...| . |||...... .||.|..|.||||||||||.||| ||.|||..|.
llhkhlkekledvlellleksa.......eeeenteess...............kespssvseiy.eekeiskeeLviGalesaflemDeqiarereayr
ISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIE
|.||||||....||||||||||||||||..|..||||.|..|||||||||||.|||..|.|||.|||.|||..|...|.||...||||.|||||||||.|
ikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsadftPeteRqRlqelaflkPeLlgkeftrlefqkRlkkkdlgqrvlyRdqnmtGWayktve
DEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDP
.||||||||.|||||||..||||||||||||.|||.|.|..||||||..||||..||..... .||||||||||||||||||||||.....|....|.|.
eeDlkfplisgegkkaRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvepedk
HRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPLI
.||| .||.||..|||.|||.|||..... .|.|||||.||||.
krytavaqeLvaaarGklkdkgWrlkeekaasvDDisvfviPlk
|
|||||||||
0049733 | PP2C-like | 81-506 | 1.5e-37 | 122.2 | In-house | 6-232 (235) | alignment | ||
Range on Protein: 81-506
Range on HMM: 6-232/235.0
AEVINAGK-STHNEDQASCevltvkkkagavtstpnrnsskrrsslpngeglqlkensesegvSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDivd
. . |. ..||| . ..... ..||| |. |. |||.|| ... |.|..
gaasdigrvrkvneDavlv............................................glllfavaDGhgghaagevasellvetllellle...
I---LknsavlpptclgeepentpansrtltraaslrggvgapgspstpptrfftekkipheclVIGALESAFKEMDLQIERERSSY--NISGGCTALIV
.. ||..||.... .. .. .. .|.||...
lllld...........................................................leealrkaflaaneallelalaspelagmgtTavva
ICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTP--ETERQRlqylafmqphllgnefthlefprrvqrkelgkkmlyrdfnmtgwayktiededlkfpl
. |||||||.|||||...|.|...... . .| |.||||
lldggklyvanvGDsrayllrdgklvqltedhspvnelerqr..........................................................
IYGEGKKARVMATIGVTRGLGDHDLKvhdsniyikpflssapevriYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQflpncdpddpHRYTLAAQ
|. .| ||. . .|| |||..|| .|.. .. ..|.|.||.||||||||.||... ... . . ||.
iitaggavrvpgrlaltralGdlllk....................pdvtvlelepgdflllasDGlwdvlsdeeivdllrs..........ldleeaae
DLVMRARGvlkdrgwrisndrLGSGDDISVYVIP
|| .|. |. |.|.| |.
rlvelala.............rggrDNiTvvvvr
|
|||||||||
PP2Cc_SM00332 | 129-505 | 4.6e-45 | 147.1 | In-house | 35-274 (274) | alignment | |||
Range on Protein: 129-505
Range on HMM: 35-274/274.0
EglqlkensesEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVDILknsavlpptclgeepentpansrtltraaslrggvgapgspstpptr
| . .. ..||||.|| .| ..|. | ... |.|. | |
v..........eeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel...............................................
fftekkiphECLVIGALESAFKEMDLQIERERSSYNI---SGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTP--ETERQRLQYLAFmqp
| | ||..||...| .| | .| . . |.||.... ..|||||.|||||...|||.....| . .| |.||.|.. .
.........eddveealkkaflstdeeileeeqskelenalsGstavvallkkedlyvanvGDSravlcrngkavqlsvdhkpedederkRikkagg...
hllgnefthlefprrvqrkelgkkmlyrdfnmtgwayktiededlkfpliygEGKKARVMATIGVTRGLGDHDLKVHDsnIYIKPFLSSAPEVRIYDLsk
.| || .. |.| .|||.|| . .|.... |.| . .|
....................................................vvekgrvngglavsrafGdhflkknk..klkepyitaepdvkvvtl..
ydHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCdpdDPHRYTLAAQDLVMRARGVlkdrgwrisndrLGSGDDISVYVI
.|..||||.|||||||||.|| . ....| . .... ||..|.. |. || |.|.| |.
..tsedeflilaSDGlwdvlsnqevvdivrkllakg...ktndpqeaaelldeeairr............ggseDniTvvvv
|
|||||||||
subfamily_KAPP-like_pd | Subfamily KAPP-like | 135-176 | 6.6e-06 | 18.3 | In-house | 25-66 (266) | alignment | ||
Range on Protein: 135-176
Range on HMM: 25-66/266.0
ENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQD
|. |. ...|||||| |||. |..|... . ..|.
ekklsncsnialfavfdGhaGkGaadaakklfpkelekllks
|
|||||||||
subfamily_PPM1D_pd | Subfamily PPM1D | 136-456 | 5.7e-15 | 48.2 | In-house | 27-265 (309) | alignment | ||
Range on Protein: 136-456
Range on HMM: 27-265/309.0
NSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQlQDIVDIlKNSAVlpptclgeepentpansrtltraaslrggvgapgspstpptrfftekki
....| .. . ..|||| | || |.. | . |..| .... ....|
eesaeelevafvavfDGHGGkeAakfarehlwsvikkq.kkflss.epedv.................................................
pheclvIGALESAFKEMDLQIERERSSY-------NISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEiipmsseftpetERQRLQYLAFMQPHLLgn
. |...|| .. ......... | || .||. |||||. |||.... . . . ..|. .. |
......leAireaflatheamkkkleeWpktksgllstaGttasvviirreklyvahvGDsaivlgvkep............kekklrakeltkdHkP..
efTHLEFPRRVQrkEL-GKKMLYRDFNMTGWAYKTIEDEDLkfpliygegKKARVMATIGVTRGLGDHDLKVHDSNIYIkpfLSSAPEVRIYDLskyDHG
..| .|.. || |. . . . | . .| .. .. . . |.| ||| . |. .. | |.| . | |
..espeekerie..elGGevaaksGvkRvvWkRprlehngp.........tvideiPFLavaRslGDlWsynaksgefv...vsPePdvkvrtl...dpn
SDDVLILATDGLWDVLSNEEVAEAITQFL
.....|||.||||.||. |.. . ...
eekfiilasDGlwnvltpedavsvvekee
|
|||||||||
subfamily_PPM1L_pd | Subfamily PPM1L | 136-314 | 2.1e-14 | 46.4 | In-house | 27-154 (269) | alignment | ||
Range on Protein: 136-314
Range on HMM: 27-154/269.0
NSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAVlpptclgeepentpansrtltraaslrggvgapgspstpptrfftekkI
. ...... .. ..|||| | || | .| . | ..|... .|. |
ediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentep................................................i
PHECLVIGALESAFKEMdlqIERERSSYNISgGCTALIVICLLGKLYVANAGDSRAIII-RNGEIIPMSSEFTPETERQR
.. |. . |. ... .|. .....|. |.|||| . .| ||| |||| ... ..|. ||.| . |. ..|
nfsklltdeilsvdekl...lekakraedia.GttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvker
|
|||||||||
subfamily_PPM1G2_pd | Subfamily PPM1G2 | 138-313 | 1.7e-17 | 56.3 | In-house | 46-161 (287) | alignment | ||
Range on Protein: 138-313
Range on HMM: 46-161/287.0
ESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEqlqdivdilknsavlpptclgeepentpansrtltraaslrggvgapgspstpptrffteKKIPH
.|. |. ....|||| |. .| |.. |.. |.. || .
ksddkslalfavfDGhGGakvakyagkklikkiak............................................................kksfk
ECLVIGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQ
| . .|. ||.|.| .. .... . | |.||..|. ||||||||||||.. .|.. .| . |..|
egaleqilkdafletDeellkdeklkdesaGstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeese
|
|||||||||
subfamily_PPM1A_pd | Subfamily PPM1A | 144-314 | 5.7e-15 | 48.4 | In-house | 42-164 (282) | alignment | ||
Range on Protein: 144-314
Range on HMM: 42-164/282.0
CHYWSLFDGHAGSGAAVVASRLLQHHITEqlqdivdilknsavlpptclgeepentpansrtltraaslrggvgapgspstppTRFF--TEKKIPHECLV
....||||||| .| .... |...|.| . . .... .. |
wsfFavfDGHaGsevakyvkkhllenile......................................................eeelkeaaleasekdev
IGALESAFKEMDLQIERERSSYNI--SGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPET--ERQR
||...| ..| .|... .... |.||. |. .|..||.|||||...|||. . .... |.. |..|
kealrqgfLaldeairelstdlktadksGsTavtvlvsekhliianlGDsRavlcrngkaaflteDHkpsrpkEkkR
|
|||||||||
subfamily_PDP_pd | Subfamily PDP | 147-296 | 2.3e-07 | 23.3 | In-house | 28-181 (398) | alignment | ||
Range on Protein: 147-296
Range on HMM: 28-181/398.0
WSLFDGHAGSGAAVVASRLLQHHITEQL---QDIVDI---LKNSAVLPP-TCLGEEPENTPANSRTLTRAASLRggvgapgspstppTRFFTEKKIPHEc
..||||.| .| |. | .... .| |..... |.... | . . ...... ..... . ...|. ... .. |
fgvfDGHggaacaeavskrLlkyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslsels.............kylqelleaeve.
LVIGALESAFKEMDLQIERERS------------SYNISGGCTALIVIcLLGKLYVANAGDSRAIIIRN
| ||..||...| .| | .|| |. | .| .|.|||.||.||.. ..
kvkealkkaFlklDkdistealkklkekslreallvalsGacallali.egtelhvAntGDcravlgvq
|
|||||||||
PP2C_2 | Protein phosphatase 2C | 149-463 | 3.2e-06 | 19.6 | Pfam-A | 29-202 (212) | alignment | ||
Range on Protein: 149-463
Range on HMM: 29-202/212.0
LFDGHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAvlpptclgeepENTPANsRTLTRAA---Slrggvgapgspstpptrfftekkipheclvigal
||. . ...||. . ..|.|..... . .. |.. .. ...... .
VADGaGsakrSdkGarlaveaagealeklleeeseqe...........eeallr.qieneilasvk..................................
esafkemDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRA-IIIRNGEIIPMSSEFTPETERQrlqyLAFMQPHLLGNEFthlefprrvqrkel
. | . .. . . ..| |.... |...... ||... .. |.||. ..... . | ... . |.... . |.
.......lkqeaeaqqeelkdyatTlllavitpgeivffqiGDgaivvrdrdgevqllgepdsgeyane....ttfltsedaeeel..............
gkkmlyrdfnmtgwayktiededlkfpliygegkkarvmatigvtrglgdhdlkvhdsniyikpflssapevriyDLSKYDHGSDDVLILATDGLWDVLS
.... . . | |.| |||..| |.
...........................................................................rirrlklepgdalllmTDGvsdslr
NEE-VAEAITQFLPNCDPDD
.|| ..| ....| . ....
keepfrellaelletleeeg
|
|||||||||
PP2C_2 | Protein phosphatase 2C | 149-463 | 3.2e-06 | 19.6 | In-house | 29-202 (212) | alignment | ||
Range on Protein: 149-463
Range on HMM: 29-202/212.0
LFDGHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAvlpptclgeepENTPANsRTLTRAA---Slrggvgapgspstpptrfftekkipheclvigal
||. . ...||. . ..|.|..... . .. |.. .. ...... .
VADGaGsakrSdkGarlaveaagealeklleeeseqe...........eeallr.qieneilasvk..................................
esafkemDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRA-IIIRNGEIIPMSSEFTPETERQrlqyLAFMQPHLLGNEFthlefprrvqrkel
. | . .. . . ..| |.... |...... ||... .. |.||. ..... . | ... . |.... . |.
.......lkqeaeaqqeelkdyatTlllavitpgeivffqiGDgaivvrdrdgevqllgepdsgeyane....ttfltsedaeeel..............
gkkmlyrdfnmtgwayktiededlkfpliygegkkarvmatigvtrglgdhdlkvhdsniyikpflssapevriyDLSKYDHGSDDVLILATDGLWDVLS
.... . . | |.| |||..| |.
...........................................................................rirrlklepgdalllmTDGvsdslr
NEE-VAEAITQFLPNCDPDD
.|| ..| ....| . ....
keepfrellaelletleeeg
|
|||||||||
PPM_PTC7 | 239-314 | 5.6e-16 | 51.7 | In-house | 69-149 (259) | alignment | |||
Range on Protein: 239-314
Range on HMM: 69-149/259.0
C-LVIGALESAFKEMDLQIERERSSYN---ISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEII-PMSSEFTPETERQR
. ... || .| ..|. .| ..|. | ...|.||.... ||||||.|||||...|.|... ... ..|. |. |
leklekalrksflaldtdeelksseantepstsGstAvvalitgsklyvAnvGDSravLcrsgnavkqltedHkpsnedEr
|
|||||||||
PP2C | Protein phosphatase 2C | 240-314 | 6.1e-14 | 45.2 | Pfam-A | 71-150 (255) | alignment | ||
Range on Protein: 240-314
Range on HMM: 71-150/255.0
LVIGALESAFKE-MDLQIERERSS-YNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEII-PMSSEFTPET--ERQR
.| || ..| . .| ...... . .. |.||.... ||||||.|||||...|..... .. .|. ||.|
kvekalrksfladtdeelksskantepsksGstavvalirgkklyvAnvGDSravLcrkdnakkeltedHkpsdedEreR
|
|||||||||
PP2C | Protein phosphatase 2C | 240-314 | 6.1e-14 | 45.2 | In-house | 71-150 (255) | alignment | ||
Range on Protein: 240-314
Range on HMM: 71-150/255.0
LVIGALESAFKE-MDLQIERERSS-YNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEII-PMSSEFTPET--ERQR
.| || ..| . .| ...... . .. |.||.... ||||||.|||||...|..... .. .|. ||.|
kvekalrksfladtdeelksskantepsksGstavvalirgkklyvAnvGDSravLcrkdnakkeltedHkpsdedEreR
|
|||||||||
subfamily_PPM1E_pd | Subfamily PPM1E | 240-314 | 1.1e-10 | 34.2 | In-house | 77-149 (265) | alignment | ||
Range on Protein: 240-314
Range on HMM: 77-149/265.0
LviGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQR
. ||..|||..| .. . . .. .|.|| .|. .|||| |||.|...|.||.. . . || |. .
a..ealkeafkltDerflqkaereklksGstavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEk
|
|||||||||
subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 240-316 | 4.8e-06 | 19.3 | In-house | 63-142 (292) | alignment | ||
Range on Protein: 240-316
Range on HMM: 63-142/292.0
LVIGALESAFKEMDLQIErerssYNISGGCTALIVICLLG-KLYVANAGDSRAIIIR-----NGEIIPMSSEFTPE--TERQRLQ
|. . |. | | .| |. . |.. .. . . .|..|| |||||.. | . |.||.| . || ||.|..
lllrildiaakldkltid.....aresattavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderaril
|
|||||||||
PPM_PTC7_SpoIIE | 241-457 | 1.2e-17 | 57.5 | In-house | 69-210 (230) | alignment | |||
Range on Protein: 241-457
Range on HMM: 69-210/230.0
VIGALESAFKEMDLQIERErssyNISGGCTALIVICLLGK--LYVANAGDSRAIIIRNGEIipmsseftpeterqrlqylafmqphllgnefthlefprr
. .|. .. ... ..| | ..|.|.||.... . |||||||||.....|...
peeilrrlnlalaadlede....psssgaTavvalidpstgklyvanaGdsppllvrddgg.......................................
vqrkelgkkmlyrdfnmtgwaykTIED-------------EdlkfpliygegkkaRVMATIGVTRGLGDHDLKVHDSNIyikpflssapEVRIYDLSKYD
..| . || . |.. || |. | . | . .. . .
.......................ererivagglpslGilpg..............rvfgvlavslapGdllllytDGvv..........eaepdtsdgel
HGSDDVLILATDGLWDVLSNEEVAEAITQFLP
| |. ||||.||||||||..|..... . |
fgkdeflilasdglwdvlspqelvdlvrdele
|
|||||||||
PP2C_SIG_SM00331 | 244-505 | 2.3e-12 | 40.0 | In-house | 65-215 (217) | alignment | |||
Range on Protein: 244-505
Range on HMM: 65-215/217.0
ALESAFKEMDLQIERErsSYNISGGCTALIVI--CLLGKLYVANAGDSRAIIIR-NGEIIPMSSeftpeterqrlqylafmqphllgnefthlefprrvq
.|..|.|... |..| . . ....|.|. . |||..||||||| ...| .... . ..
elsqalkrlnraiyee..keekgmfaTlllalydfssgklsyanaGdsrpyllrdgklveilkd....................................
rkelgkkmlyrdfnmtgwayktiededlkfpliygegkkarvmatigvtrglgdhdlkvhdsniYIKPFLSSAPEVRiYDLSKYDHGSDDVLILATDGLW
. |. |||. .| .. . .|.|.|.||||.
................................................................vegaplGlepevs.vdirelelekgdllllytDGlt
DVL-----SNEEVAEAITQFLpNCDPDDPHRytLAAQDLVMRARGVLKdrgwrisndrlgsGDDISVYVI
.. .|.. |...... .. ... .. ..|. .|.| . |||.| |.
earsekgfaeerleeiledlv.dseaqelaq..kiveellelakgsng.............eDdiTvvvv
|
|||||||||
subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 244-314 | 4.9e-07 | 22.3 | In-house | 76-143 (255) | alignment | ||
Range on Protein: 244-314
Range on HMM: 76-143/255.0
ALESAFKEMDLQIererSSYNISGGCTALIVICLLGKLYVANAGDSRAIII-RNGEIIPMSSEFTPETERQR
.|. |.||...|| | . . |.|| |. . | |.|| ||||... ..| .| . | |...
slkkaykeistqi....serpkfiGttaasvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseesee
|
|||||||||
subfamily_PPM1K_pd | Subfamily PPM1K | 245-314 | 2.2e-08 | 26.5 | In-house | 71-148 (263) | alignment | ||
Range on Protein: 245-314
Range on HMM: 71-148/263.0
LESAFKEMDLQIERERSSY-----NISGGCTALIVICLLG-KLYVANAGDSRAIIIRNGEIIPMSSEFTPETE--RQR
| ||.|.| ...| | | || ... | .| .|. ||||||. |||. .... .|| | ..|
lknafeeldkklkrylefsvaeaellssGttatvsllrdGtelvlaslGdsrailcrnGkakkltrdhdPeleeeker
|
|||||||||
subfamily_ILKAP_pd | Subfamily ILKAP | 248-298 | 7.6e-07 | 21.6 | In-house | 92-144 (293) | alignment | ||
Range on Protein: 248-298
Range on HMM: 92-144/293.0
AFKEMDLQIERE--RSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGE
.||. | . .. .. |.|| .|. | ||||| |||.|...|. |
sfkktdeefLklaskakPvWkdGstatvvlvldnvlyvanlGdskavlvrkke
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 252-313 | 2.8e-11 | 36.1 | In-house | 281-342 (473) | alignment | ||
Range on Protein: 252-313
Range on HMM: 281-342/473.0
MDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQ
. |. . |. . . |.|| ... ||.||||||||... |||. . .| . || |
eeldgseekeepGedsGttAvvaLlkekklivAnaGDsRcvlsrnGkAldlslDHkPeDevE
|
|||||||||
subfamily_TAB1_pd | Subfamily TAB1 | 262-296 | 1.3e-09 | 30.3 | In-house | 124-158 (333) | alignment | ||
Range on Protein: 262-296
Range on HMM: 124-158/333.0
SYNISGGCTALIVICLLGKLYVANAGDSRAIIIRN
.|||| ||.... . ||||||.|||||.....
eeeisgGttAvvalifnnkLyVaNvGdsrAllvkr
|
|||||||||
subfamily_PPTC7_pd | Subfamily PPTC7 | 263-306 | 5.1e-06 | 19.1 | In-house | 83-128 (252) | alignment | ||
Range on Protein: 263-306
Range on HMM: 83-128/252.0
YNISGGCTALIVICLLG--KLYVANAGDSRAIIIRNGEIIPMSSEF
.. |..||.||. ||..|| ||| ...|.|... |.|
vpvlGssTacivvldksdkklesanlGDSgflvvRkgkvvfrskeq
|
|||||||||
subfamily_PP2D1_pd | Subfamily PP2D1 | 276-314 | 3e-06 | 19.2 | In-house | 185-225 (492) | alignment | ||
Range on Protein: 276-314
Range on HMM: 185-225/492.0
CLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETE--RQR
|| ||.||||. .|...|.|. | . | ||. . |.|
eelgvlyianaGnvqAvLcreGkaiiLtreHtprnkkERtR
|
|||||||||
subfamily_PP2D1_pd | Subfamily PP2D1 | 373-457 | 4.6e-11 | 35.1 | In-house | 233-307 (492) | alignment | ||
Range on Protein: 373-457
Range on HMM: 233-307/492.0
IYGEGKKARVMATIGVTRGLGDH-DLKVHDSnIYIKPFLSSapeVRIydlSKydhgSDDVLILATDGLWDVLSNEEVAEAITQFLP
.. ..|...| ...||||| . |.|.. | . ..| . | | . . . .|.||. |||.|||.|||.. ..|.|.
vvkseknglvnGildttRGLGnyGdpkLkks.vipePktts...vkl...de....aaqflvlAsnGlWevlseeevlsLvkqtla
|
|||||||||
subfamily_ILKAP_pd | Subfamily ILKAP | 378-505 | 5.2e-08 | 25.4 | In-house | 177-290 (293) | alignment | ||
Range on Protein: 378-505
Range on HMM: 177-290/293.0
KKARVMATIGVTRGLGDHDLKVHDsniyikpfLSSAPEVRIYDLSKYdhgsDDVLILATDGLWDVLSNEEVAEAITQFLPNCdpddPHRYTLAAQDLVMR
.. ||. ..|.| .|| | ..| |.|. .|.. | ..|| ||||.|.|..||.. |.. | . . ... .. . .
rdgrvlGvlevsrsiGdgrfkrlG........vistPdvkkceLten....dlfvvlaCdGLwkvfsadevvkfilkvlede....eddrkikeeekksk
ARGVLKDRGWRISND--RLGSGDDISVYVI
. .. |.... . ||.|...| ..
eevrfevacnrlaseavkrgssdnvtvllv
|
|||||||||
subfamily_PPM1A_pd | Subfamily PPM1A | 379-459 | 3.8e-15 | 49.0 | In-house | 174-250 (282) | alignment | ||
Range on Protein: 379-459
Range on HMM: 174-250/282.0
KARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKydhgSDDVLILATDGLWDVLSNEEVAEAITQFLPNC
. ||. .. |.| |||...| ... . .|. |||.. . |. .|| |.|| ||.|||||.|||.| ... |
vsRvnGaLAvsRalGDyeykeeeekkaeeqlvsaepevtsierse....eddflvlacDGiwDvlsdeevvelvrkrleva
|
|||||||||
PP2C | Protein phosphatase 2C | 379-458 | 2.1e-14 | 46.7 | Pfam-A | 161-231 (255) | alignment | ||
Range on Protein: 379-458
Range on HMM: 161-231/255.0
KARVMATIGVTRGLGDHDLKVHDsniyiKPFLSSAPEVRiydLSKYDHGsDDVLILATDGLWDVLSNEEVAEAITQFLPN
. || .. |.| |||..|| . ... |..|.|. | . |. ||||.||||||||..|... ....|
ngrvngsLavsRalGdfelkpke.....eqlvsaePdvt...svkltee.defliLasdGlwdvlsdqeavdlvrselsk
|
|||||||||
PP2C | Protein phosphatase 2C | 379-458 | 2.1e-14 | 46.7 | In-house | 161-231 (255) | alignment | ||
Range on Protein: 379-458
Range on HMM: 161-231/255.0
KARVMATIGVTRGLGDHDLKVHDsniyiKPFLSSAPEVRiydLSKYDHGsDDVLILATDGLWDVLSNEEVAEAITQFLPN
. || .. |.| |||..|| . ... |..|.|. | . |. ||||.||||||||..|... ....|
ngrvngsLavsRalGdfelkpke.....eqlvsaePdvt...svkltee.defliLasdGlwdvlsdqeavdlvrselsk
|
|||||||||
PPM_PTC7 | 379-457 | 5.8e-13 | 41.9 | In-house | 164-235 (259) | alignment | |||
Range on Protein: 379-457
Range on HMM: 164-235/259.0
KARVMATIGVTRGLGDHDLKVHDSniyIKPFLSSAPEVRiydLSKYDHGsDDVLILATDGLWDVLSNEEVAEAITQFLP
. || .. |.| .||..|| . .. .|..|.. | | |. ||||.||||||.|..|... ....|
ngrvngvlavsRafGdfelkpket...eeqlvsaePdis...stkidee.defliLasdGlwdvvsdqeavdlvrsels
|
|||||||||
subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 379-454 | 4.9e-09 | 28.8 | In-house | 159-222 (255) | alignment | ||
Range on Protein: 379-454
Range on HMM: 159-222/255.0
KARVMATIGVTRGLGDhdlkvhdsnIYIKPFLSSAPEVRIydlSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQ
.|| |. |.| ||| ....||. . |.. | . .| |||| ||.||..|.|| | . .
tsrvnGtlavsralGd.........sflePfvvpdPdlsq...sleiskkdkflilacdGiwdlisdeeaveivag
|
|||||||||
subfamily_PPM1G2_pd | Subfamily PPM1G2 | 379-454 | 5.5e-09 | 28.4 | In-house | 174-245 (287) | alignment | ||
Range on Protein: 379-454
Range on HMM: 174-245/287.0
KARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSkydhGSDDVLILATDGLWDVLSNEEVAEAITQ
|| .. . | |||. | ... |.| . .|. .|. |.|| ||.||||.|.|| . . .
lnrvngnLalsralgDfefkknvkkkpeeqivtavPDvlvkkld....eddeflvLaCDGiWDvltnkevvdlvre
|
|||||||||
subfamily_PPM1K_pd | Subfamily PPM1K | 379-454 | 1.1e-06 | 20.9 | In-house | 163-227 (263) | alignment | ||
Range on Protein: 379-454
Range on HMM: 163-227/263.0
KARVMATIGVTRGLGDHDLKVHDsnIYikpflsSAPEVRIYdlsKYDHGSDDVLILATDGLWDVLSNEEVAEAITQ
| .| . . .|| ||| ||| . . . || . | ||..| |.| |||. .|....|... ...
kplvngrlamtrslGdldlkryG..vi......atPetksl...kvdhaadsflvlitdgisfvvnsqelcdlvrl
|
|||||||||
subfamily_PPM1E_pd | Subfamily PPM1E | 380-459 | 6.8e-10 | 31.6 | In-house | 165-231 (265) | alignment | ||
Range on Protein: 380-459
Range on HMM: 165-231/265.0
ARVMATIGVTRGLGDHDLkvhdsniyiKPFLSSAPEVRIYDLSkydhGSDDVLILATDGLWDVLSNEEVAEAITQFLPNC
|| .. |.| .|| .| ||..|. ..| ..| ||...||||.||||||. .||| .....|| .
wRvnGvLsvsRaiGDvkl.........kpyvsgeadvaeveld....gseeylilacDGlwDvvneeevvklveefladg
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 380-457 | 3.7e-07 | 22.5 | In-house | 357-430 (473) | alignment | ||
Range on Protein: 380-457
Range on HMM: 357-430/473.0
ARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKydhgSDDVLILATDGLWDVLSNEEVAEAITQFLP
|| . . | |||| | . .| |.... | . |. |.||.||.|.|.. .|| . ... |
gRvnGGLnlsRAlGDhaYkkneeLplkeqmisAlPDikvltlte....edeFlvlAcDGiWnvmesqevvdfvraklk
|
|||||||||
subfamily_PPM1L_pd | Subfamily PPM1L | 381-456 | 2.1e-09 | 30.0 | In-house | 171-236 (269) | alignment | ||
Range on Protein: 381-456
Range on HMM: 171-236/269.0
RVMATIGVTRGLGDHDLKvhDSNIYIkpflsSAPEVRIYDLSKYDhgsDDVLILATDGLWDVLSNEEVAEAITQFL
|| . ..| |||. || | |. | . |.. .|| ... . ||||.||||| .|||| . | . |
rvaGvlatsralGdyplk..dknlvi.....adpdiltfdlddhk...peflilasdGlwdtfsneeavrfikerl
|
|||||||||
subfamily_Dicty-PPM-1_pd | Subfamily Dicty-PPM-1 | 384-454 | 9.6e-07 | 20.9 | In-house | 179-240 (276) | alignment | ||
Range on Protein: 384-454
Range on HMM: 179-240/276.0
ATIGVTRGLGDHDLKVHDSNIYIKPFLSSApevriYDLSKYdhgsDDVLILATDGLWDVLSNEEVAEAITQ
. |.| |||| .| . . .|..|. . |. . |. ||.|.||||||.| .. | .
nGlavsralGdhfikelniGlisepyvsnr.....illtpf....dkflivasdGlwdvisGkdaiekvks
|
|||||||||
subfamily_KAPP-like_pd | Subfamily KAPP-like | 384-454 | 9.7e-07 | 21.1 | In-house | 169-230 (266) | alignment | ||
Range on Protein: 384-454
Range on HMM: 169-230/266.0
ATIGVTRGLGDHDLKVHDSNIYIKPFLSSApevriYDLSKYdhgsDDVLILATDGLWDVLSNEEVAEAITQ
. |.| |||| .| . . .|..|. . |. . |. ||.|.||||||.| .. | .
nGlavsralGdhfikelniGlisepyvsnr.....illtpf....dkflivasdGlwdvisGkdaiekvks
|
|||||||||
subfamily_PDP_pd | Subfamily PDP | 403-465 | 7.3e-11 | 34.8 | In-house | 263-321 (398) | alignment | ||
Range on Protein: 403-465
Range on HMM: 263-321/398.0
NIYIKPFLSSAPEVRIYDLSKydhgSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPH
. . |.|.. ||| . |.. .| |.||||||||.||||||.. ....| . . ..|
dyktPPYltaePevtshklre....ndkFLvlatDGLwdllsneevvslVgehlakkkekepv
|
|||||||||
subfamily_PPTC7_pd | Subfamily PPTC7 | 425-483 | 4.2e-07 | 22.6 | In-house | 163-217 (252) | alignment | ||
Range on Protein: 425-483
Range on HMM: 163-217/252.0
DHGSDDVLILATDGLWDVLSNEEVAEAITQFLpncdPDDPHRYTLAAQDLVMRARGVLK
. ..|...||||||.| |...|..|.... .... .|..|...|| . .
avkkgDiivlatDGlfDNlledeileilkelk....eseksslqslakklaekarelsl
|
|||||||||
PPM_PTC7_SpoIIE_motif | 428-505 | 6.6e-07 | 22.9 | In-house | 11-78 (81) | alignment | |||
Range on Protein: 428-505
Range on HMM: 11-78/81.0
SDDVLILATDGLWDVL-------SNEEVAeaitQFLPNCdpdDPHRYTLAAQDLVMRARGvlkdrgwrisNDRLGSGDDISVYVI
.|||.|.||||.. ..||.. ...... . .. ..|. || ... |.. .. |||.. |.
pgdvllLyTDGltEardsdgelfgkeell....rladra...egkslqeladklvdevle..........ngsgereDDitllvl
|
|||||||||
PPM_PTC7_motif | 433-476 | 1.9e-08 | 27.7 | In-house | 1-40 (51) | alignment | |||
Range on Protein: 433-476
Range on HMM: 1-40/51.0
ILATDGLWDVLSNEEVAEAITQFLP-NCDpddphRYTLAAQDLVM
|||.||||||||..|. . ....| . . ... ||..||
iLAsDGLWDvlsdqeavdlvrdqlskkgl.....spqeaAeklvd
|